The average bus between Cardiff and Slough takes 3h 49m and the fastest bus takes 3h 4m. There is a bus service every few hours from Cardiff to Slough. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between Cardiff and Slough. The earliest departure is at 1:40 AM at night, and the last departure from Cardiff is at 11:40 PM which arrives into Slough at 3:24 AM. All services require a transfer, and take on average 3h 49m. The schedules shown below are for the next available departures.

4h 49m • 1 change

4h 24m • 1 change
Arrives next day

3h 45m • 1 change

3h 13m • 1 change

3h 53m • 1 change

3h 38m • 1 change

4h 8m • 1 change

3h 13m • 1 change

3h 53m • 1 change

3h 38m • 1 change

4h 8m • 1 change

3h 13m • 1 change

3h 53m • 1 change

3h 38m • 1 change

4h 8m • 1 change
Want to know about travelling from Cardiff to Slough? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Cardiff to Slough. However, there are services departing from Cardiff station and arriving at Slough station via Heathrow Central Bus Station station. The journey, including transfers, takes approximately 3h 49m.
Cardiff to Slough bus services, operated by National Express, depart from Sophia Gardens station.
Cardiff to Slough bus services, operated by National Express, arrive at Heathrow Central Bus Station.
Book your Cardiff to Slough bus tickets online with National Express and First Berkshire & The Thames Valley.
The distance between Cardiff and Slough is 178.9 km. The road distance is 232 km.
National Express operates a bus from Sophia Gardens to Heathrow Central Bus Station hourly. Tickets cost £26–65 and the journey takes 2h 50m.