The average bus between Cape Cod and Chicago takes 32h 4m and the fastest bus takes 26h 39m. There is at least one bus per day from Cape Cod to Chicago. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run once daily between Cape Cod and Chicago. The earliest departure is at 11:46 AM in the morning, and the last departure from Cape Cod is at 6:46 PM which arrives into Chicago at 6:10 AM. All services require a transfer at Hyannis Transportation Center and take an average of 32h 4m. The schedules shown below are for the next available departures.
Arrives next day



25h 39m • 3 changes
Arrives +2 days



35h 24m • 3 changes
Arrives next day



25h 39m • 3 changes
Arrives +2 days



35h 24m • 3 changes
Want to know about travelling from Cape Cod to Chicago? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Cape Cod to Chicago. However, there are services departing from Cape Cod station and arriving at Chicago station via Boston South Buses. The journey, including transfers, takes approximately 32h 4m.
Cape Cod to Chicago bus services, operated by Cape Cod Regional Transit Authority, depart from Hyannis Transportation Center station.
Cape Cod to Chicago bus services, operated by Cape Cod Regional Transit Authority, arrive at Chicago Bus Station.
The distance between Cape Cod and Chicago is 1,442.8 km. The road distance is 1,894 km.
You can take a bus from Town Hall Lawton Bus Shelter to Chicago Bus Station via Hyannis Transportation Center, Boston, Bus Terminal South Station, Boston, and New York Midtown in around 25h 54m.