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How to get fromBuffalo to Myrtle Beachby plane, bus (Flixbus, Greyhound), train, bus, car or bus (Greyhound)

Find Transport to Myrtle Beach

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There are 6 ways to get from Buffalo to Myrtle Beach by plane, bus (Flixbus, Greyhound), train, bus, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Buffalo Niagara International Airport

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Myrtle Beach (MYR)plane plane BUF - MYR
    5h 21m
    $134–793
  2. Bus

    1. Take the bus from Buffalo to Newark Penn Stationbus bus
    2. Take the bus from Newark Penn Station to Raleigh Bus Stationbus bus
    3. Take the bus from Raleigh Bus Station to Wilmington Cape Fear Public Transitbus bus
    4. Take the bus from Wilmington Cape Fear Public Transit to Myrtle Beach Bus Stationbus bus
    25h 5m
    $146–273
  3. Train, bus

    1. Take the train from Buffalo to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Charleston Amtrak Stationtrain train
    3. Take the bus from Charleston Bus Station to Myrtle Beach Bus Stationbus bus
    26h 20m
    $197–407
  4. Drive 760 mi

    1. Drive from Buffalo to Myrtle Beachcar car 760 mi
    15h 37m
    $139–201
  5. Bus to Rochester, fly

    1. Take the bus from Buffalo, NY to Rochester, NYbus bus
    2. Fly from Rochester (ROC) to Myrtle Beach (MYR)plane plane ROC - MYR
    5h 31m
    $164–748
  6. Bus via Chesapeake

    1. Take the bus from Buffalo to New Yorkbus bus
    2. Take the bus from Times Square – 37th St. to Norfolk, VA - Best Squarebus bus
    3. Take the bus from Norfolk to Myrtle Beach Bus Stationbus bus
    26h 6m
    $157–433

Buffalo to Myrtle Beach by bus

Calendar7Weekly Buses
Duration25h 5mAverage Duration
Ticket$146Cheapest Price
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Questions & Answers

What companies run services between Buffalo, NY, USA and Myrtle Beach, SC, USA?

Southwest Airlines, American Airlines, and Delta fly from Buffalo Niagara International Airport (BUF) to Myrtle Beach (MYR) every 3 hours. Alternatively, you can take a bus from Buffalo to Myrtle Beach Bus Station via Newark Penn Station, Raleigh Bus Station, and Wilmington Cape Fear Public Transit in around 25h 5m.

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