There are 6 ways to get from Buffalo to Myrtle Beach by plane, bus (Flixbus, Greyhound), train, bus, car, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Buffalo Niagara International Airport
best- Fly from Buffalo Niagara International Airport (BUF) to Myrtle Beach (MYR)plane BUF - MYR
5h 21m$134–793Bus
- Take the bus from Buffalo to Newark Penn Stationbus
- Take the bus from Newark Penn Station to Raleigh Bus Stationbus
- Take the bus from Raleigh Bus Station to Wilmington Cape Fear Public Transitbus
- Take the bus from Wilmington Cape Fear Public Transit to Myrtle Beach Bus Stationbus
25h 5m$146–273Train, bus
- Take the train from Buffalo to Ny Moynihan Train Hall At Penn Stationtrain
- Take the train from Ny Moynihan Train Hall At Penn Station to Charleston Amtrak Stationtrain
- Take the bus from Charleston Bus Station to Myrtle Beach Bus Stationbus
26h 20m$197–407Drive 760 mi
- Drive from Buffalo to Myrtle Beachcar 760 mi
15h 37m$139–201Bus to Rochester, fly
- Take the bus from Buffalo, NY to Rochester, NYbus
- Fly from Rochester (ROC) to Myrtle Beach (MYR)plane ROC - MYR
5h 31m$164–748Bus via Chesapeake
- Take the bus from Buffalo to New Yorkbus
- Take the bus from Times Square – 37th St. to Norfolk, VA - Best Squarebus
- Take the bus from Norfolk to Myrtle Beach Bus Stationbus
26h 6m$157–433
Buffalo to Myrtle Beach by bus
Questions & Answers
The cheapest way to get from Buffalo to Myrtle Beach is to drive which costs $130 - $200 and takes 15h 37m.
The fastest way to get from Buffalo to Myrtle Beach is to fly which takes 5h 21m and costs $130 - $800.
No, there is no direct bus from Buffalo to Myrtle Beach station. However, there are services departing from Buffalo and arriving at Myrtle Beach Bus Station via Newark Penn Station, Raleigh Bus Station and Wilmington Cape Fear Public Transit. The journey, including transfers, takes approximately 25h 5m.
The distance between Buffalo and Myrtle Beach is 656 miles. The road distance is 764.4 miles.
The best way to get from Buffalo to Myrtle Beach without a car is to bus which takes 25h 5m and costs $140 - $280.
It takes approximately 5h 21m to get from Buffalo to Myrtle Beach, including transfers.
Buffalo to Myrtle Beach bus services, operated by Flixbus USA, depart from Buffalo station.
The best way to get from Buffalo to Myrtle Beach is to fly which takes 5h 21m and costs $130 - $800. Alternatively, you can bus, which costs $140 - $280 and takes 25h 5m.
Buffalo to Myrtle Beach bus services, operated by Flixbus USA, arrive at Newark Penn Station.
Yes, the driving distance between Buffalo to Myrtle Beach is 764 miles. It takes approximately 15h 37m to drive from Buffalo to Myrtle Beach.
What companies run services between Buffalo, NY, USA and Myrtle Beach, SC, USA?
Southwest Airlines, American Airlines, and Delta fly from Buffalo Niagara International Airport (BUF) to Myrtle Beach (MYR) every 3 hours. Alternatively, you can take a bus from Buffalo to Myrtle Beach Bus Station via Newark Penn Station, Raleigh Bus Station, and Wilmington Cape Fear Public Transit in around 25h 5m.
- Website
- aa.com
Flights from Buffalo Niagara International Airport to Myrtle Beach via Charlotte
- Ave. Duration
- 5h 6m
- When
- Every day
- Estimated price
- $120–700
Flights from Buffalo Niagara International Airport to Myrtle Beach via Reagan Washington
- Ave. Duration
- 4h 24m
- When
- Thursday and Sunday
- Estimated price
- $120–700
Flights from Buffalo Niagara International Airport to Myrtle Beach via Philadelphia
- Ave. Duration
- 5h 43m
- When
- Every day
- Estimated price
- $130–700
Flights from Buffalo Niagara International Airport to Myrtle Beach via New York La Guardia
- Ave. Duration
- 8h 46m
- When
- Friday
- Estimated price
- $140–750
Flights from Rochester to Myrtle Beach via Philadelphia
- Ave. Duration
- 4h 40m
- When
- Every day
- Estimated price
- $95–550
Flights from Rochester to Myrtle Beach via Charlotte
- Ave. Duration
- 4h 40m
- When
- Tuesday and Wednesday
- Estimated price
- $95–550
Flights from Rochester to Myrtle Beach via Reagan Washington
- Ave. Duration
- 4h 48m
- When
- Thursday and Sunday
- Estimated price
- $90–500
- Website
- southwest.com
Flights from Buffalo Niagara International Airport to Myrtle Beach via Baltimore
- Ave. Duration
- 4h 31m
- When
- Monday to Saturday
- Estimated price
- $120–700
Flights from Rochester to Myrtle Beach via Baltimore
- Ave. Duration
- 4h 17m
- When
- Monday to Saturday
- Estimated price
- $90–500
- Website
- delta.com
Flights from Buffalo Niagara International Airport to Myrtle Beach via Atlanta
- Ave. Duration
- 6h 16m
- When
- Every day
- Estimated price
- $160–800
Flights from Buffalo Niagara International Airport to Myrtle Beach via New York La Guardia
- Ave. Duration
- 5h 34m
- When
- Every day
- Estimated price
- $140–750
Flights from Buffalo Niagara International Airport to Myrtle Beach via Detroit
- Ave. Duration
- 5h 56m
- When
- Every day
- Estimated price
- $140–750
Flights from Rochester to Myrtle Beach via New York La Guardia
- Ave. Duration
- 5h 10m
- When
- Saturday and Sunday
- Estimated price
- $100–550
- Website
- flybreeze.com
Flights from Rochester to Myrtle Beach
- Ave. Duration
- 2h 5m
- When
- Thursday and Sunday
- Estimated price
- $160–650
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Buffalo to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 8h 27m
- Frequency
- 3 times a day
- Estimated price
- $65–130
- Website
- https://www.amtrak.com/home.html
Train from Ny Moynihan Train Hall At Penn Station to Charleston Amtrak Station
- Ave. Duration
- 13h 28m
- Frequency
- Twice daily
- Estimated price
- $120–270
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Buffalo to Newark Penn Station
- Ave. Duration
- 7h 45m
- Frequency
- 5 times a day
- Estimated price
- $50–85
- Schedules at
- flixbus.com
Bus from Newark Penn Station to Raleigh Bus Station
- Ave. Duration
- 10h 20m
- Frequency
- Once daily
- Estimated price
- $55–130
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Buffalo to Newark Penn Station
- Ave. Duration
- 8h 15m
- Frequency
- Once daily
- Estimated price
- $50–85
- Website
- https://www.greyhound.com/
Bus from Newark Penn Station to Raleigh Bus Station
- Ave. Duration
- 9h 40m
- Frequency
- 3 times a day
- Estimated price
- $60–120
- Website
- https://www.greyhound.com/
Bus from Raleigh Bus Station to Wilmington Cape Fear Public Transit
- Ave. Duration
- 3h 5m
- Frequency
- Twice daily
- Estimated price
- $23–40
- Website
- https://www.greyhound.com/
Bus from Wilmington Cape Fear Public Transit to Myrtle Beach Bus Station
- Ave. Duration
- 1h 35m
- Frequency
- Once daily
- Estimated price
- $15–21
- Website
- https://www.greyhound.com/
Bus from Charleston Bus Station to Myrtle Beach Bus Station
- Ave. Duration
- 2h 25m
- Frequency
- Once daily
- Estimated price
- $12–14
- Website
- https://www.greyhound.com/
Bus from Norfolk to Myrtle Beach Bus Station
- Ave. Duration
- 9h 5m
- Frequency
- Once daily
- Estimated price
- $45–100
- Website
- https://www.greyhound.com/
- Phone
- +1-844-800-6828
- pr@ourbus.com
- Website
- ourbus.com
Bus from Buffalo, NY to Rochester, NY
- Ave. Duration
- 1h 5m
- Frequency
- Once daily
- Estimated price
- $20–55
- Website
- https://www.ourbus.com
- Phone
- +1 800-858-8555
- Website
- trailways.com
Bus from Buffalo to New York
- Ave. Duration
- 7h 55m
- Frequency
- 3 times a day
- Estimated price
- $60–280
- Website
- https://trailways.com
- Schedules at
- https://trailways.com/schedules/
- Saver
- $60–260
- Flexible
- $110–280
- Phone
- +1 757-456-5555
- Website
- sprinterbus.net
Bus from Times Square – 37th St. to Norfolk, VA - Best Square
- Ave. Duration
- 7h
- Frequency
- Once daily
- Estimated price
- $50–60
- Website
- https://www.sprinterbus.net
- Passenger
- $50–60
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