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How to get fromBuffalo to Myrtle Beachby plane, bus (Greyhound, Flixbus), train, bus or car

Find Transport to Myrtle Beach

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There are 6 ways to get from Buffalo to Myrtle Beach by plane, bus (Greyhound, Flixbus), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Buffalo Niagara International Airport

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Myrtle Beach (MYR)plane plane BUF - MYR
    5h 21m
    $124–743

  2. Bus

    cheapest
    1. Take the bus from Buffalo, NY to Akron, OHbus bus
    2. Take the bus from Akron, OH to Charleston, WVbus bus
    3. Take the bus from Charleston, WV to Charlotte Bus Stationbus bus
    4. Take the bus from Charlotte Bus Station to Florence Bus Stationbus bus
    5. Take the bus from Florence to Myrtle Beach, SCbus bus
    21h 20m
    $111–341

  3. Train, bus

    1. Take the train from Buffalo to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Charleston Amtrak Stationtrain train
    3. Take the bus from Charleston Bus Station to Myrtle Beach Bus Stationbus bus
    26h 20m
    $205–579

  4. Drive 760.5 mi

    1. Drive from Buffalo to Myrtle Beachcar car 760.5 mi
    15h 29m
    $139–201

  5. Bus to Rochester, fly

    1. Take the bus from Buffalo, NY to Rochester, NYbus bus
    2. Fly from Rochester (ROC) to Myrtle Beach (MYR)plane plane ROC - MYR
    5h 31m
    $164–518

  6. Bus via Chesapeake

    1. Take the bus from Buffalo to Pittsburghbus bus
    2. Take the bus from Pittsburgh Intermodal Station to Washington Union Stationbus bus
    3. Take the bus from Washington Union Station to Norfolkbus bus
    4. Take the bus from Norfolk to Myrtle Beach Bus Stationbus bus
    29h 15m
    $154–420

Buffalo to Myrtle Beach by bus

Calendar7Weekly Buses
Duration21h 20mAverage Duration
Ticket$111Cheapest Price
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Questions & Answers

What companies run services between Buffalo, NY, USA and Myrtle Beach, SC, USA?

Southwest Airlines, American Airlines, and Delta fly from Buffalo Niagara International Airport (BUF) to Myrtle Beach (MYR) every 4 hours. Alternatively, you can take a bus from Buffalo, NY to Myrtle Beach, SC via Akron, OH, Charleston, WV, Charlotte Bus Station, Florence Bus Station, and Florence in around 21h 20m.

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