The average bus between Brookline and Buffalo takes 12h 52m and the fastest bus takes 10h 30m. There is at least one bus per day from Brookline to Buffalo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run once daily between Brookline and Buffalo. The earliest departure is at 11:55 AM in the morning, and the last departure from Brookline is at 7:43 PM which arrives into Buffalo at 10:35 PM. All services require a transfer at Lincoln St @ Essex St and take an average of 12h 52m. The schedules shown below are for the next available departures.
Want to know about travelling from Brookline to Buffalo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Brookline to Buffalo. However, there are services departing from Brookline station and arriving at Buffalo station via Buffalo. The journey, including transfers, takes approximately 12h 52m.
Brookline to Buffalo bus services, operated by MBTA, depart from Boston station.
Brookline to Buffalo bus services, operated by MBTA, arrive at Buffalo station.
Book your Brookline to Buffalo bus tickets online with MBTA and Greyhound USA.
The distance between Brookline and Buffalo is 637.6 km. The road distance is 767 km.
Greyhound USA operates a bus from Boston to Buffalo once daily. Tickets cost $75–120 and the journey takes 10h 5m.
