The average bus between Amsterdam and Melsele takes 4h 17m and the fastest bus takes 3h 16m. There is a bus service every few hours from Amsterdam to Melsele. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between Amsterdam and Melsele. The earliest departure is at 6:15 AM in the morning, and the last departure from Amsterdam is at 11:30 PM which arrives into Melsele at 6:06 AM. All services require a transfer at Antwerp Rooseveltplaats and take an average of 4h 17m. The schedules shown below are for the next available departures.


4h 46m • 2 changes


3h 46m • 2 changes


4h 6m • 2 changes


3h 46m • 2 changes


4h 26m • 2 changes


4h 51m • 2 changes


3h 41m • 2 changes


4h • 2 changes


4h 54m • 2 changes


3h 54m • 2 changes


4h • 2 changes


3h 46m • 2 changes


4h 46m • 2 changes


3h 46m • 2 changes


4h 6m • 2 changes


4h 41m • 2 changes
Want to know about travelling from Amsterdam to Melsele? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Amsterdam to Melsele. However, there are services departing from Amsterdam station and arriving at Melsele station via Antwerp Rooseveltplaats. The journey, including transfers, takes approximately 4h 17m.
Amsterdam to Melsele bus services, operated by FlixBus, depart from Amsterdam Sloterdijk station.
Amsterdam to Melsele bus services, operated by FlixBus, arrive at Antwerp Rooseveltplaats station.
The distance between Amsterdam and Melsele is 134.8 km. The road distance is 182 km.
FlixBus operates a bus from Amsterdam Sloterdijk to Antwerp Rooseveltplaats hourly. Tickets cost €11–19 and the journey takes 2h 20m. BlaBlaCar Bus also services this route every 3 hours.