The average bus between Amsterdam and Melsele takes 4h 7m and the fastest bus takes 2h 56m. There is a bus service every few hours from Amsterdam to Melsele. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 2 hours between Amsterdam and Melsele. The earliest departure is at 6:15 AM in the morning, and the last departure from Amsterdam is at 11:30 PM which arrives into Melsele at 7:04 AM. All services require a transfer at Antwerp - Rooseveltplaats and take an average of 4h 7m. The schedules shown below are for the next available departures.


3h 31m • 2 changes


4h 11m • 2 changes


4h 33m • 2 changes


3h 20m • 2 changes


3h 31m • 2 changes


4h 11m • 2 changes


3h 31m • 2 changes


3h 31m • 2 changes


4h 31m • 2 changes


3h 31m • 2 changes


3h 46m • 2 changes


3h 31m • 2 changes


4h 26m • 2 changes


4h 31m • 2 changes


3h 41m • 2 changes


3h 45m • 2 changes
Want to know about travelling from Amsterdam to Melsele? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Amsterdam to Melsele. However, there are services departing from Amsterdam station and arriving at Melsele station via Antwerp - Rooseveltplaats. The journey, including transfers, takes approximately 4h 7m.
Amsterdam to Melsele bus services, operated by FlixBus, depart from Amsterdam City Center - Sloterdijk station.
Amsterdam to Melsele bus services, operated by FlixBus, arrive at Antwerp - Rooseveltplaats station.
The distance between Amsterdam and Melsele is 134.8 km. The road distance is 177 km.
BlaBlaCar Bus operates a bus from Amsterdam City Center - Sloterdijk to Antwerp - Rooseveltplaats every 4 hours. Tickets cost €12–23 and the journey takes 2h 30m. FlixBus also services this route hourly.