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Altamonte Springs to Florida Keys buses

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Trip Overview

The average bus between Altamonte Springs and Florida Keys takes 15h 42m and the fastest bus takes 13h 19m. The bus service runs several times per day from Altamonte Springs to Florida Keys. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

15h 42m
Duration
389 mi
Distance
$78
Average price
Twice daily
Frequency

Altamonte Springs to Florida Keys bus times

Buses run twice daily between Altamonte Springs and Florida Keys. The earliest departure is at 6:15 PM in the evening, and the last departure from Altamonte Springs is at 10:55 PM which arrives into Florida Keys at 12:15 PM. All services require a transfer at N Garland Ave & W Amelia St and take an average of 15h 42m. The schedules shown below are for the next available departures.

Departing Saturday, November 7, 2026

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    Arrives next day

    Lynx Central Florida TransportLynx Central Florida TransportFlixbus USAGreyhound USAKey West Transit16h 24m • 4 changes

Departing Sunday, November 8, 2026

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    Arrives next day

    Lynx Central Florida TransportLynx Central Florida TransportFlixbus USAGreyhound USAKey West Transit14h 59m • 4 changes
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    Arrives next day

    Lynx Central Florida TransportLynx Central Florida TransportFlixbus USAGreyhound USAKey West Transit17h 24m • 4 changes

Departing Monday, November 9, 2026

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    Arrives next day

    Lynx Central Florida TransportLynx Central Florida TransportFlixbus USAGreyhound USAKey West Transit13h 19m • 4 changes

Departing Tuesday, November 10, 2026

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    Arrives next day

    Lynx Central Florida TransportLynx Central Florida TransportFlixbus USAGreyhound USAKey West Transit17h 59m • 4 changes
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    Arrives next day

    Lynx Central Florida TransportLynx Central Florida TransportFlixbus USAGreyhound USAKey West Transit16h 14m • 4 changes

Departing Wednesday, November 11, 2026

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    Arrives next day

    Lynx Central Florida TransportLynx Central Florida TransportFlixbus USAGreyhound USAKey West Transit17h 59m • 4 changes
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    Arrives next day

    Lynx Central Florida TransportLynx Central Florida TransportFlixbus USAGreyhound USAKey West Transit16h 14m • 4 changes

Departing Thursday, November 12, 2026

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    Arrives next day

    Lynx Central Florida TransportLynx Central Florida TransportFlixbus USAGreyhound USAKey West Transit13h 19m • 4 changes

Departing Friday, November 13, 2026

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    Arrives next day

    Lynx Central Florida TransportLynx Central Florida TransportFlixbus USAGreyhound USAKey West Transit13h 19m • 4 changes

Frequently asked questions

Want to know about travelling from Altamonte Springs to Florida Keys? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Altamonte Springs to Florida Keys.ExpandLaunch map view
  • Distance: 388.8 mi
  • Duration: 15h 42m

What companies run services between Altamonte Springs, FL, USA and Florida Keys, FL, USA?

You can take a bus from E Altamonte Dr & Station St to Florida Keys via N Garland Ave & W Amelia St, Florida Mall, Orlando, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 12h 42m.

Operators