There are 8 ways to get from Zephyrhills to Key West by bus, plane, ferry, car, taxi, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus, line 275 bus, line 400 bus to Tampa, fly
best- Take the bus from Zephyrhills Downtown Transfer Station to Wiregrass Park and Ride
- Take the bus from Wiregrass Park n Ride to University Area Transit Center
- Take the bus from University Area Transit Center to Kennedy Blvd @ Pierce St MetroRapid
- Fly from Tampa (TPA) to Key West International Airport (EYW)TPA - EYW
6h 18m$124–506Bus, line 275 bus, line 300 bus to Saint Petersburg–Clearwater International Airport, fly
cheapest- Take the bus from Zephyrhills Downtown Transfer Station to Wiregrass Park and Ride
- Take the bus from Wiregrass Park n Ride to Marion Transit Center
- Take the bus from Marion Transit Parking Lot to Psta 34Th St Layby - Platform - B
- Fly from Saint Petersburg–Clearwater International Airport (PIE) to Key West International Airport (EYW)PIE - EYW
7h 56m$70–212Bus, ferry
- Take the bus from Dade City to Fort MyersHouston
- Take the ferry from Fort Myers Beach, FL to Key West, FLFort Myers Beach
10h 49m$216–246Drive 389.9 mi
- Drive from Zephyrhills to Key West389.9 mi
7h 55m$72–103Drive to Orlando Sanford, fly
- Drive from Zephyrhills to Orlando Sanford (SFB)
- Fly from Orlando Sanford (SFB) to Key West International Airport (EYW)SFB - EYW
3h 11m$83–537Taxi, train, train to Orlando, fly
- Take the taxi from Zephyrhills to Lakeland Amtrak Station
- Take the train from Lakeland Amtrak Station to Kissimmee Amtrak Station
- Take the train from Kissimmee to Sand Lake Road
- Fly from Orlando (MCO) to Key West International Airport (EYW)MCO - EYW
5h 15m$244–720Bus to Sarasota–Bradenton International Airport, fly
- Take the bus from Dade City to Bradenton
- Fly from Sarasota–Bradenton International Airport (SRQ) to Key West International Airport (EYW)SRQ - EYW
10h 47m$470–678Train, bus
- Take the train from Lakeland to Delray Beach Amtrak
- Take the train from Delray Beach Station to Miami Airport Station
- Take the bus from Miami Airport Station to Big Pine Key
- Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd StreetLks
12h 57m$163–265
Tampa (TPA) to Key West International Airport (EYW) flights
Questions & Answers
The cheapest way to get from Zephyrhills to Key West is to drive which costs $70 - $110 and takes 7h 55m.
The fastest way to get from Zephyrhills to Key West is to drive and fly which takes 3h 11m and costs $80 - $550.
The distance between Zephyrhills and Key West is 295 miles. The road distance is 392.2 miles.
The best way to get from Zephyrhills to Key West without a car is to bus and ferry which takes 10h 49m and costs $210 - $250.
It takes approximately 6h 18m to get from Zephyrhills to Key West, including transfers.
Yes, the driving distance between Zephyrhills to Key West is 392 miles. It takes approximately 7h 55m to drive from Zephyrhills to Key West.
There are 816+ hotels available in Key West.
What companies run services between Zephyrhills, FL, USA and Key West, FL, USA?
There is no direct connection from Zephyrhills to Key West. However, you can take the bus to Wiregrass Park and Ride, take the line 275 bus to University Area Transit Center, take the line 400 bus to Kennedy Blvd @ Pierce St MetroRapid, walk to Downtown Tampa, take the taxi to Tampa Airport, walk to Tampa (TPA) airport, fly to Key West International Airport (EYW), then take the taxi to Key West. Alternatively, you can take a bus from Zephyrhills Downtown Transfer Station to Key West, FL via 5th St & Martin Luther King Blvd, Dade City, Fort Myers, and Fort Myers Beach, FL in around 10h 49m.
- Website
- allegiantair.com
Flights from Orlando Sanford to Key West International Airport
- Ave. Duration
- 1h 10m
- When
- Thursday and Sunday
- Estimated price
- $55–400
Flights from Saint Petersburg–Clearwater International Airport to Key West International Airport
- Ave. Duration
- 1h 1m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $50–190
Flights from Sarasota–Bradenton International Airport to Key West International Airport via Knoxville
- Ave. Duration
- 6h 46m
- When
- Monday
- Estimated price
- $240–900
Flights from Sarasota–Bradenton International Airport to Key West International Airport via Covington
- Ave. Duration
- 6h 48m
- When
- Monday
- Estimated price
- $260–950
- Website
- aa.com
Flights from Tampa to Key West International Airport via Miami
- Ave. Duration
- 3h 14m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $45–300
Flights from Sarasota–Bradenton International Airport to Key West International Airport via Miami
- Ave. Duration
- 5h 14m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $70–470
Flights from Sarasota–Bradenton International Airport to Key West International Airport via Charlotte
- Ave. Duration
- 6h 25m
- When
- Every day
- Estimated price
- $150–750
- Website
- flybreeze.com
Flights from Tampa to Key West International Airport
- Ave. Duration
- 1h 7m
- When
- Every day
- Estimated price
- $110–500
Flights from Orlando to Key West International Airport
- Ave. Duration
- 1h 15m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $110–600
- Website
- delta.com
Flights from Sarasota–Bradenton International Airport to Key West International Airport via Atlanta
- Ave. Duration
- 5h 45m
- When
- Every day
- Estimated price
- $130–700
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Lakeland Amtrak Station to Kissimmee Amtrak Station
- Ave. Duration
- 42 min
- Frequency
- Once daily
- Estimated price
- $17–18
- Website
- https://www.amtrak.com/home.html
Train from Lakeland to Delray Beach Amtrak
- Ave. Duration
- 3h 34m
- Frequency
- Once daily
- Estimated price
- $23–90
- Website
- https://www.amtrak.com/home.html
- Coach Seat - Advance Purchase
- $25–50
- Coach Seat short notice purchase
- $23–90
- Business - advance purchase
- $30–160
- Business Class
- $50–230
- Phone
- +1 855-724-5411
- info@sunrail.com
- Website
- sunrail.com
Train from Kissimmee to Sand Lake Road
- Ave. Duration
- 20 min
- Frequency
- Hourly
- Estimated price
- $2–4
- Website
- https://sunrail.com
- Phone
- +1 800-874-7245
- Website
- tri-rail.com
Train from Delray Beach Station to Miami Airport Station
- Ave. Duration
- 1h 24m
- Frequency
- Hourly
- Estimated price
- $5–9
- Website
- https://www.tri-rail.com
- Weekend | Holiday
- $5
- Weekday
- $6–9
- Phone
- +1 727-834-3322
- info@gopasco.com
- Website
- pascocountyfl.net
Bus from Zephyrhills Downtown Transfer Station to Wiregrass Park and Ride
- Ave. Duration
- 50 min
- Frequency
- Every 2 hours
- Estimated price
- $2
- Website
- https://www.pascocountyfl.net/services/gopasco/index.php
- Phone
- +1 813-254-4278
- Website
- gohart.org
Bus from Wiregrass Park n Ride to University Area Transit Center
- Ave. Duration
- 39 min
- Frequency
- Hourly
- Estimated price
- $2
- Website
- HART
Bus from University Area Transit Center to Kennedy Blvd @ Pierce St MetroRapid
- Ave. Duration
- 41 min
- Frequency
- Every 30 minutes
- Website
- HART
Bus from Wiregrass Park n Ride to Marion Transit Center
- Ave. Duration
- 1h 21m
- Frequency
- Every 2 hours
- Estimated price
- $2
- Website
- HART
- Phone
- +1 800-923-1799
- contactus@omexusa.net
- Website
- omnibusexpress.com
Bus from Dade City to Fort Myers
- Ave. Duration
- 3h 52m
- Frequency
- Once daily
- Estimated price
- $55–70
- Schedules at
- omnibusexpress.com
Bus from Dade City to Bradenton
- Ave. Duration
- 1h 40m
- Frequency
- Once daily
- Estimated price
- $45–60
- Schedules at
- omnibusexpress.com
- Phone
- +1 727-540-1900
- ride@psta.net
- Website
- psta.net
Bus from Marion Transit Parking Lot to Psta 34Th St Layby - Platform - B
- Ave. Duration
- 50 min
- Frequency
- Every 4 hours
- Estimated price
- $3
- Schedules at
- psta.net
- Adult
- $3
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 35m
- Frequency
- Twice daily
- Estimated price
- $21–29
- Website
- https://www.greyhound.com/
- Phone
- +1 (305) 600-1455
- Website
- cityofkeywest-fl.gov
Bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Street
- Ave. Duration
- 1h 9m
- Frequency
- Every 3 hours
- Estimated price
- $2–4
- Schedules at
- https://www.cityofkeywest-fl.gov/595/Schedules-and-Route-Maps
- Phone
- +1 239-463-5733
- Website
- keywestexpress.net
Ferry from Fort Myers Beach, FL to Key West, FL
- Ave. Duration
- 4h
- Frequency
- Once daily
- Estimated price
- $130
- Website
- https://www.keywestexpress.net
- Ave. Duration
- 35 min
- Estimated price
- $110–140
Wesley Chapel Taxi
- Phone
- +1-813-995-7030
- Website
- wesleychapeltaxi.com
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide


















