There are 8 ways to get from Yuma to Santa Ana by train, bus, bus (Flixbus, Amtrak), car, plane, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train, line 59 bus
best- Take the train from Yuma Amtrak to Pomona Amtraktrain Texas Eagle / ...
- Take the bus from Ring-Brea Mall to The Depot At Santa Ana Dock 3bus 59
6h 16m$52–119Bus via Tijuana
cheapest- Take the bus from 3rd Street @ Gila Street to William Brook Ave @ B Streetbus 95
- Take the bus from San Luis Río Colorado to Tijuanabus
- Take the bus from Tijuana - Plaza El Mexicano to Santa Anabus
10h 35m$38–117Bus
- Take the bus from Yuma County Area Transit to Los Angeles Downtownbus FlixBus 2054
- Take the bus from Los Angeles to Santa Anabus Amtrak Thruway Connecting Service
8h 2m$43–74Drive 247.5 mi
- Drive from Yuma to Santa Anacar 247.5 mi
4h 8m$46–66Fly Yuma International Airport to John Wayne Airport Orange County
- Fly from Yuma International Airport (YUM) to John Wayne Airport Orange County (SNA)plane YUM - SNA
5h$100–477Bus to Phoenix, fly to John Wayne Airport Orange County
- Take the bus from Yuma County Area Transit to Phoenix Bus Stationbus
- Fly from Phoenix (PHX) to John Wayne Airport Orange County (SNA)plane PHX - SNA
5h 32m$321–552Fly Yuma International Airport to Los Angeles International Airport, train
- Fly from Yuma International Airport (YUM) to Los Angeles International Airport (LAX)plane YUM - LAX
- Take the train from L.A. Union Station to Santa Anatrain
8h 8m$56–287Bus to Imperial County Airport, fly to Los Angeles International Airport, train
- Take the bus from Winterhaven Dr @ Jimbo's Towing to 7th Street @ State Streetbus
- Fly from Imperial County Airport (IPL) to Los Angeles International Airport (LAX)plane IPL - LAX
- Take the train from L.A. Union Station to Santa Anatrain
6h 41m$117–201
Yuma to Santa Ana by train and bus
Questions & Answers
The cheapest way to get from Yuma to Santa Ana is to bus which costs $40 - $75 and takes 8h 2m.
The fastest way to get from Yuma to Santa Ana is to drive which takes 4h 8m and costs $45 - $70.
No, there is no direct bus from Yuma to Santa Ana. However, there are services departing from Yuma County Area Transit and arriving at Santa Ana via Los Angeles. The journey, including transfers, takes approximately 8h 2m.
The distance between Yuma and Santa Ana is 250 miles. The road distance is 249 miles.
The best way to get from Yuma to Santa Ana without a car is to train and line 59 bus which takes 6h 16m and costs $50 - $120.
It takes approximately 6h 16m to get from Yuma to Santa Ana, including transfers.
Yuma to Santa Ana bus services, operated by Flixbus USA, depart from Yuma County Area Transit station.
The best way to get from Yuma to Santa Ana is to bus which takes 8h 2m and costs $40 - $75. Alternatively, you can fly, which costs $100 - $480 and takes 5h.
Yuma to Santa Ana bus services, operated by Flixbus USA, arrive at Los Angeles Downtown station.
Santa Ana is 1h behind Yuma. It is currently 6:27 AM in Yuma and 5:27 AM in Santa Ana.
What companies run services between Yuma, AZ, USA and Santa Ana, CA, USA?
You can take a bus from Yuma County Area Transit to Santa Ana via Los Angeles Downtown and Los Angeles in around 8h 2m. Alternatively, American Airlines and Alaska Airlines, Inc. fly from Yuma International Airport (YUM) to John Wayne Airport Orange County (SNA) every 4 hours.
- Website
- aa.com
Flights from Yuma International Airport to John Wayne Airport Orange County via Phoenix
- Ave. Duration
- 4h 31m
- When
- Every day
- Estimated price
- $70–440
Flights from Yuma International Airport to John Wayne Airport Orange County via Dallas/Ft.Worth
- Ave. Duration
- 7h 27m
- When
- Every day
- Estimated price
- $200–900
Flights from Phoenix to John Wayne Airport Orange County
- Ave. Duration
- 1h 32m
- When
- Every day
- Estimated price
- $65–430
Flights from Yuma International Airport to Los Angeles International Airport via Phoenix
- Ave. Duration
- 4h 14m
- When
- Every day
- Estimated price
- $40–260
Flights from Yuma International Airport to Los Angeles International Airport via Dallas/Ft.Worth
- Ave. Duration
- 7h 6m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $110–500
Flights from Yuma International Airport to Los Angeles International Airport via Phoenix, Las Vegas
- Ave. Duration
- 7h 31m
- When
- Every day
- Estimated price
- $45–280
- Website
- southwest.com
Flights from Phoenix to John Wayne Airport Orange County
- Ave. Duration
- 1h 23m
- When
- Every day
- Estimated price
- $65–430
- Website
- alaskaair.com
Flights from Yuma International Airport to John Wayne Airport Orange County via Phoenix
- Ave. Duration
- 4h 28m
- When
- Every day
- Estimated price
- $70–440
Flights from Yuma International Airport to John Wayne Airport Orange County via Phoenix, Tucson
- Ave. Duration
- 6h 32m
- When
- Every day
- Estimated price
- $85–490
Flights from Phoenix to John Wayne Airport Orange County
- Ave. Duration
- 1h 32m
- When
- Every day
- Estimated price
- $65–430
- Website
- iflysouthern.com
Flights from Imperial County Airport to Los Angeles International Airport
- Ave. Duration
- 1h 31m
- When
- Every day
- Estimated price
- $90–160
- Website
- flyfrontier.com
Flights from Phoenix to John Wayne Airport Orange County
- Ave. Duration
- 1h 27m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $65–430
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Yuma Amtrak to Pomona Amtrak
- Ave. Duration
- 3h 15m
- Frequency
- 6 times a week
- Estimated price
- $45–120
- Website
- https://www.amtrak.com/home.html
- Phone
- (800) 371-LINK (5465)
- Website
- metrolinktrains.com
Train from L.A. Union Station to Santa Ana
- Ave. Duration
- 55 min
- Frequency
- Every 3 hours
- Estimated price
- $8–12
- Website
- https://metrolinktrains.com
- Phone
- +1 714-560-6282
- Website
- octa.net
Bus from Ring-Brea Mall to The Depot At Santa Ana Dock 3
- Ave. Duration
- 1h 4m
- Frequency
- Hourly
- Estimated price
- $1–2
- Schedules at
- octa.net
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Yuma County Area Transit to Los Angeles Downtown
- Ave. Duration
- 5h 50m
- Frequency
- 6 times a week
- Estimated price
- $30–60
- Schedules at
- flixbus.com
Bus from Yuma County Area Transit to Phoenix Bus Station
- Ave. Duration
- 2h 55m
- Frequency
- 6 times a week
- Estimated price
- $21–40
- Schedules at
- flixbus.com
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Los Angeles to Santa Ana
- Ave. Duration
- 1h 5m
- Frequency
- Once daily
- Estimated price
- $10–18
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 928-783-2235
- Website
- ycipta.org
Bus from 3rd Street @ Gila Street to William Brook Ave @ B Street
- Ave. Duration
- 1h 10m
- Frequency
- Hourly
- Estimated price
- $1–2
- Website
- https://www.ycipta.org/
- Youth 5-18 w/ Student ID, Seniors 65+, Disabled
- $1
- Adults 19-64
- $2
Bus from Winterhaven Dr @ Jimbo's Towing to 7th Street @ State Street
- Ave. Duration
- 1h 16m
- Frequency
- 6 times a week
- Estimated price
- $1–2
- Website
- https://www.ycipta.org/
- Youth 5-18 w/ Student ID, Seniors 65+, Disabled
- $1
- Adults 19-64
- $2
- Phone
- +52 55 4440 3187
- servicioalcliente@geb.mx
- Website
- autobuseselite.com.mx
Bus from San Luis Río Colorado to Tijuana
- Ave. Duration
- 3h 24m
- Frequency
- 4 times a day
- Estimated price
- $28–45
- Schedules at
- autobuseselite.com.mx
- Book at
- autobuseselite.com.mx
- Phone
- +52 55 5141 4300
- contacto@odm.com.mx
- Website
- odm.com.mx
Bus from San Luis Río Colorado to Tijuana
- Ave. Duration
- 4h
- Frequency
- Every 30 minutes
- Estimated price
- $35–55
- Schedules at
- odm.com.mx
- Book at
- odm.com.mx
- Phone
- +52 55 4440 3187
- servicioalcliente@geb.mx
- Website
- chihuahuenses.com.mx
Bus from San Luis Río Colorado to Tijuana
- Ave. Duration
- 3h 25m
- Frequency
- Twice daily
- Estimated price
- $30–50
- Schedules at
- chihuahuenses.com.mx
- Book at
- chihuahuenses.com.mx
- Phone
- +52 644 410 2444
- atencionaclientes@tufesa.com.mx
- Website
- tufesa.com.mx
Bus from San Luis Río Colorado to Tijuana
- Ave. Duration
- 4h 10m
- Frequency
- Every 4 hours
- Estimated price
- $16–29
- Schedules at
- tufesa.com.mx
- Book at
- tufesa.com.mx
- Plus
- $16–28
- Titanium
- $18–29
- Phone
- +52 664 299 0487
- servicios@acnautobuses.com
- Website
- acnautobuses.com
Bus from San Luis Río Colorado to Tijuana
- Ave. Duration
- 5h
- Frequency
- Once daily
- Estimated price
- $50–80
- Schedules at
- acnautobuses.com
- Book at
- acnautobuses.com
- Phone
- +1-800-231-2222
- ifsr@greyhound.com
- Website
- greyhound.com.mx
Bus from Tijuana - Plaza El Mexicano to Santa Ana
- Ave. Duration
- 4h 20m
- Frequency
- 3 times a day
- Estimated price
- $21–35
- Schedules at
- greyhound.com.mx
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More Questions & Answers
Yes, the driving distance between Yuma to Santa Ana is 249 miles. It takes approximately 4h 8m to drive from Yuma to Santa Ana.
Book your Yuma to Santa Ana bus tickets online with Omio.
There are 1491+ hotels available in Santa Ana.

































