There are 11 ways to get from Wisconsin to South Carolina by plane, train, bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly Milwaukee to Charlotte  •  4 h 13 min

  1. Fly from Milwaukee (MKE) to Charlotte (CLT) MKE - CLT

$217 - $692

Cheapest option

Bus Megabus  •  25 h 25 min

  1. Take the bus from Milwaukee, WI to Chicago
  2. Take the bus from Chicago to Marta Civic Center Station - Nb
  3. Take the bus from Atlanta GA to Columbia, SC
  4. Take the bus from Columbia, SC to Florence, SC

$112 - $173

9 alternative options

Fly Madison to Charlotte  •  5 h

  1. Fly from Madison (MSN) to Charlotte (CLT) MSN - CLT

$249 - $944

Train to Chicago O'Hare, fly to Greenville/Spartanburg  •  5 h 36 min

  1. Take the train from Kenosha to Clybourn
  2. Fly from Chicago O'Hare (ORD) to Greenville/Spartanburg (GSP) ORD - GSP

$182 - $610

Train to Chicago O'Hare, fly to Columbia  •  5 h 44 min

  1. Take the train from Kenosha to Clybourn
  2. Fly from Chicago O'Hare (ORD) to Columbia (CAE) ORD - CAE

$246 - $595

Train to Chicago Midway, fly to Charleston  •  6 h 38 min

  1. Take the train from Kenosha to Chicago OTC
  2. Fly from Chicago Midway (MDW) to Charleston (CHS) MDW - CHS

$183 - $618

Train to Chicago O'Hare, fly to Charleston  •  6 h 47 min

  1. Take the train from Kenosha to Clybourn
  2. Fly from Chicago O'Hare (ORD) to Charleston (CHS) ORD - CHS

$154 - $488

Bus Greyhound USA  •  24 h 39 min

  1. Take the bus from Milwaukee, Wi to Chicago, Il
  2. Take the bus from Chicago, Il to Atlanta, Ga
  3. Take the bus from Atlanta, GA to Florence, SC

$123 - $277

Train  •  28 h 34 min

  1. Take the train from Milwaukee Intermodal Station to Chicago Union Station
  2. Take the train from Chicago Union Station to Washington Union Station
  3. Take the train from Washington Union Station to Florence Amtrak

$193 - $549

Train via Alexandria Amtrak  •  34 h 4 min

  1. Take the train from Milwaukee Intermodal Station to Chicago Union Station
  2. Take the train from Chicago Union Station to Alexandria Amtrak
  3. Take the train from Alexandria Amtrak to Florence Amtrak

$208 - $579

Drive  •  16 h 19 min

  1. Drive from Milwaukee to Florence 975.5 miles

$95 - $140

Questions & Answers

No, there is no direct bus from Wisconsin to South Carolina. However, there are services departing from Milwaukee, Wi and arriving at Florence, SC via Chicago, Il, Peachtree St @ Alabama St and Atlanta, GA. The journey, including transfers, takes approximately 24 h 39 min.

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No, there is no direct train from Wisconsin station to South Carolina. However, there are services departing from Milwaukee Intermodal Station and arriving at Florence Amtrak via Chicago Union Station and Washington Union Station. The journey, including transfers, takes approximately 28 h 34 min.

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The distance between Wisconsin and South Carolina is 897 miles. The road distance is 975.5 miles.

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The best way to get from Wisconsin to South Carolina without a car is to bus which takes 24 h 39 min and costs .

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It takes approximately 4 h 13 min to get from Wisconsin to South Carolina, including transfers.

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Wisconsin to South Carolina bus services, operated by Greyhound USA, depart from Milwaukee, Wi station.

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Wisconsin to South Carolina train services, operated by Amtrak, arrive at Milwaukee Intermodal Station.

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The best way to get from Wisconsin to South Carolina is to fly which takes 4 h 13 min and costs . Alternatively, you can bus, which costs and takes 24 h 39 min, you could also train, which costs and takes 28 h 34 min.

Mode details

The quickest flight from Milwaukee Airport to Charlotte Airport is the direct flight which takes 2 h 12 min.

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Wisconsin to South Carolina bus services, operated by South Eastern Stages, arrive at Florence, SC station.

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Map of how to get from Wisconsin to South Carolina.
Launch map view
  • Distance: 896.9 miles
  • Duration: 4 h 13 min

What companies run services between Wisconsin, USA and South Carolina, USA?

American Airlines, United Airlines and two other airlines fly from Milwaukee to Rock Hill hourly. Alternatively, you can take a bus from Milwaukee to Florence via Chicago, Il, Atlanta, Ga, Peachtree St @ Alabama St, Peachtree St Sw @ Brotherton Transportation Mall, and Atlanta, GA in around 24 h 39 min.

Airlines
American Airlines
Website
aa.com
Flights from Milwaukee to Charlotte
Ave. Duration
2 h 16 min
When
Every day
Estimated price
$180 - $700
Flights from Milwaukee to Charlotte via Chicago O'Hare
Ave. Duration
4 h 4 min
When
Every day
Estimated price
$180 - $700
Flights from Madison to Charlotte
Ave. Duration
2 h 20 min
When
Every day
Estimated price
$180 - $850
Flights from Madison to Charlotte via Chicago O'Hare
Ave. Duration
4 h 14 min
When
Every day
Estimated price
$180 - $850
Flights from Chicago O'Hare to Greenville/Spartanburg
Ave. Duration
1 h 48 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$280 - $800
Flights from Chicago O'Hare to Greenville/Spartanburg via Charlotte
Ave. Duration
3 h 47 min
When
Every day
Estimated price
$280 - $800
Flights from Chicago O'Hare to Columbia via Charlotte
Ave. Duration
4 h 7 min
When
Every day
Estimated price
$400 - $1,100
Flights from Chicago O'Hare to Columbia via Reagan Washington
Ave. Duration
4 h 35 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$400 - $1,100
Flights from Chicago O'Hare to Charleston
Ave. Duration
2 h 29 min
When
Monday, Wednesday, Thursday, Friday, Saturday and Sunday
Estimated price
$290 - $1,200
Flights from Chicago O'Hare to Charleston via Charlotte
Ave. Duration
4 h 7 min
When
Every day
Estimated price
$290 - $1,200
Flights from Chicago O'Hare to Charleston via Reagan Washington
Ave. Duration
4 h 21 min
When
Sunday
Estimated price
$290 - $1,200
Delta
Website
delta.com
Flights from Milwaukee to Charlotte via Atlanta
Ave. Duration
4 h 14 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$160 - $750
Flights from Milwaukee to Charlotte via Detroit
Ave. Duration
4 h 13 min
When
Every day
Estimated price
$160 - $750
Flights from Madison to Charlotte via Detroit
Ave. Duration
4 h 22 min
When
Every day
Estimated price
$170 - $850
Flights from Madison to Charlotte via Atlanta
Ave. Duration
4 h 16 min
When
Every day
Estimated price
$180 - $900
Flights from Chicago O'Hare to Greenville/Spartanburg via Atlanta
Ave. Duration
3 h 51 min
When
Every day
Estimated price
$260 - $1,300
Flights from Chicago O'Hare to Greenville/Spartanburg via Detroit
Ave. Duration
4 h
When
Saturday
Estimated price
$260 - $1,300
Flights from Chicago O'Hare to Columbia via Atlanta
Ave. Duration
4 h 16 min
When
Every day
Estimated price
$420 - $1,000
Flights from Chicago Midway to Charleston via Atlanta
Ave. Duration
4 h 39 min
When
Every day
Estimated price
$280 - $1,400
Flights from Chicago Midway to Charleston via Detroit
Ave. Duration
4 h 31 min
When
Every day
Estimated price
$280 - $1,400
Flights from Chicago O'Hare to Charleston via Atlanta
Ave. Duration
4 h 9 min
When
Every day
Estimated price
$320 - $1,400
United Airlines
Website
united.com
Flights from Milwaukee to Charlotte via Chicago O'Hare
Ave. Duration
4 h 5 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$140 - $1,200
Flights from Madison to Charlotte via Chicago O'Hare
Ave. Duration
4 h 8 min
When
Every day
Estimated price
$190 - $900
Flights from Chicago O'Hare to Greenville/Spartanburg
Ave. Duration
1 h 55 min
When
Every day
Estimated price
$280 - $1,100
Flights from Chicago O'Hare to Columbia
Ave. Duration
2 h 2 min
When
Every day
Estimated price
$320 - $900
Flights from Chicago O'Hare to Columbia via Washington Dulles
Ave. Duration
4 h 11 min
When
Every day
Estimated price
$320 - $900
Flights from Chicago O'Hare to Charleston
Ave. Duration
2 h 22 min
When
Every day
Estimated price
$300 - $1,100
Southwest Airlines
Website
southwest.com
Flights from Chicago Midway to Charleston
Ave. Duration
2 h 1 min
When
Every day
Estimated price
$350 - $1,600
Flights from Chicago Midway to Charleston via Nashville
Ave. Duration
3 h 42 min
When
Saturday and Sunday
Estimated price
$350 - $1,600
Flights from Chicago Midway to Charleston via St. Louis
Ave. Duration
4 h 25 min
When
Sunday
Estimated price
$350 - $1,600
Flights from Chicago Midway to Charleston via Baltimore
Ave. Duration
4 h 32 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$350 - $1,600
Frontier Airlines
Website
flyfrontier.com
Flights from Chicago O'Hare to Charleston
Ave. Duration
2 h 17 min
When
Monday and Friday
Estimated price
$110 - $550
Train operators
Metra
Phone
+1 312-322-6777
Website
metrarail.com
Train from Kenosha to Clybourn
Ave. Duration
1 h 26 min
Frequency
Every 4 hours
Estimated price
$8 - $11
Schedules at
metrarail.com
Train from Kenosha to Chicago OTC
Ave. Duration
1 h 40 min
Frequency
Every 4 hours
Estimated price
$8 - $11
Schedules at
metrarail.com
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Milwaukee Intermodal Station to Chicago Union Station
Ave. Duration
1 h 29 min
Frequency
Every 4 hours
Estimated price
$28 - $60
Website
amtrak.com
Coach Seat
$28 - $45
Flexi Coach Seat
$50 - $75
Business Coach Seat
$40 - $60
Room
$150 - $220
Train from Chicago Union Station to Washington Union Station
Ave. Duration
17 h 25 min
Frequency
Once daily
Estimated price
$100 - $310
Website
amtrak.com
Coach Seat
$100 - $160
Flexi Coach Seat
$190 - $280
Business Coach Seat
$220 - $310
Room
$440 - $600
Train from Washington Union Station to Florence Amtrak
Ave. Duration
7 h 40 min
Frequency
Twice daily
Estimated price
$65 - $180
Website
amtrak.com
Coach Seat
$65 - $100
Flexi Coach Seat
$110 - $170
Business Coach Seat
$120 - $180
Room
$280 - $400
Train from Chicago Union Station to Alexandria Amtrak
Ave. Duration
23 h 14 min
Frequency
4 times a week
Estimated price
$120 - $350
Website
amtrak.com
Coach Seat
$120 - $180
Flexi Coach Seat
$210 - $310
Business Coach Seat
$250 - $350
Room
$490 - $700
Train from Alexandria Amtrak to Florence Amtrak
Ave. Duration
7 h 21 min
Frequency
Twice daily
Estimated price
$60 - $170
Website
amtrak.com
Coach Seat
$60 - $95
Flexi Coach Seat
$110 - $170
Business Coach Seat
$120 - $170
Room
$280 - $390
Bus operators
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Milwaukee, Wi to Chicago, Il
Ave. Duration
1 h 55 min
Frequency
Every 20 minutes
Estimated price
$15 - $35
Website
greyhound.com
Economy
$15 - $23
Flexible
$27 - $35
Bus from Chicago, Il to Atlanta, Ga
Ave. Duration
15 h 45 min
Frequency
Hourly
Estimated price
$70 - $180
Website
greyhound.com
Economy
$70 - $120
Flexible
$130 - $180
South Eastern Stages
Phone
+1 877.836.7607 / 404.591.2750
Email
info@sestages.com
Website
southeasternstages.com
Bus from Atlanta, GA to Florence, SC
Ave. Duration
5 h 30 min
Frequency
Once daily
Estimated price
$35 - $60
Schedules at
southeasternstages.com
Bus from Columbia, SC to Florence, SC
Ave. Duration
1 h 20 min
Frequency
Once daily
Estimated price
$19 - $30
Schedules at
southeasternstages.com
Megabus
Phone
877-462-6342
Website
us.megabus.com
Bus from Milwaukee, WI to Chicago
Ave. Duration
1 h 40 min
Frequency
4 times a day
Estimated price
$10 - $21
Book at
megabus.com
Bus from Chicago to Marta Civic Center Station - Nb
Ave. Duration
14 h 5 min
Frequency
Twice daily
Estimated price
$60 - $85
Book at
megabus.com
Bus from Atlanta GA to Columbia, SC
Ave. Duration
4 h 15 min
Frequency
Twice daily
Estimated price
$21 - $35
Book at
megabus.com

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More Questions & Answers

South Carolina is 1 h ahead of Wisconsin. It is currently 11:39 PM in Wisconsin and 12:39 AM in South Carolina.

Wisconsin to South Carolina train services, operated by Amtrak, arrive at Florence Amtrak station.

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Yes, the driving distance between Wisconsin to South Carolina is 976 miles. It takes approximately 16 h 19 min to drive from Wisconsin to South Carolina.

Get driving directions

United Airlines, American Airlines and Delta offer flights from Milwaukee Airport to Charlotte Airport.

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Book your Wisconsin to South Carolina train tickets online with Rome2rio.

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There are 17+ hotels available in South Carolina. Prices start at $51 USD per night.

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The best way to get from Wisconsin to Milwaukee Airport is to bus which takes 28 min and costs .

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