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How to get fromWisconsin to Missouriby plane, train (Amtrak), bus (Greyhound, Flixbus), car, bus or train

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There are 9 ways to get from Wisconsin to Missouri by plane, train (Amtrak), bus (Greyhound, Flixbus), car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly General Mitchell International Airport to Lambert–St. Louis International Airport

    best
    1. Fly from General Mitchell International Airport (MKE) to Lambert–St. Louis International Airport (STL)planeMKE - STL
    3h 30m
    $255–455
  2. Bus

    cheapest
    1. Take the bus from Milwaukee Intermodal Station to Chicago Bus Stationbus
    2. Take the bus from Chicago Bus Station to Des Moinesbus
    3. Take the bus from Des Moines to Kansas Citybus
    13h 49m
    $84–257
  3. Train (Amtrak)

    1. Take the train from Milwaukee to Chicago Union StationtrainHiawatha Service / ...
    2. Take the train from Chicago Union Station to Kansas CitytrainSouthwest Chief / ...
    10h 3m
    $88–221
  4. Drive 546.8 mi

    1. Drive from Milwaukee to Kansas Citycar546.8 mi
    9h 30m
    $100–145
  5. Fly General Mitchell International Airport to Kansas City

    1. Fly from General Mitchell International Airport (MKE) to Kansas City (MCI)planeMKE - MCI
    4h 32m
    $282–652
  6. Bus to Chicago O'Hare International Airport, fly to Columbia Regional Airport

    1. Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus
    2. Fly from Chicago O'Hare International Airport (ORD) to Columbia Regional Airport (COU)planeORD - COU
    4h 31m
    $125–383
  7. Bus to Chicago O'Hare International Airport, fly to Lambert–St. Louis International Airport

    1. Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus
    2. Fly from Chicago O'Hare International Airport (ORD) to Lambert–St. Louis International Airport (STL)planeORD - STL
    4h 52m
    $208–541
  8. Bus to Chicago O'Hare International Airport, fly to Springfield-Branson National Airport

    1. Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus
    2. Fly from Chicago O'Hare International Airport (ORD) to Springfield-Branson National Airport (SGF)planeORD - SGF
    4h 44m
    $101–358
  9. Train to Chicago Midway International Airport, fly to Lambert–St. Louis International Airport

    1. Take the train from Kenosha to Chicago OTCtrain
    2. Fly from Chicago Midway International Airport (MDW) to Lambert–St. Louis International Airport (STL)planeMDW - STL
    5h 34m
    $84–565

Wisconsin to Missouri by train and tram (Amtrak)

Calendar14Weekly Services
Duration10h 3mAverage Duration
Ticket$88Cheapest Price
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Questions & Answers

What companies run services between Wisconsin, USA and Missouri, USA?

Southwest Airlines flies from General Mitchell International Airport (MKE) to Lambert–St. Louis International Airport (STL) twice daily. Alternatively, you can take a train from Milwaukee to Metro Center via Chicago Union Station, Kansas City, and Union Station in around 10h 3m.

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