There are 9 ways to get from Wisconsin to Missouri by plane, train (Amtrak), bus (Greyhound, Flixbus), car, bus, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly General Mitchell International Airport to Lambert–St. Louis International Airport
best- Fly from General Mitchell International Airport (MKE) to Lambert–St. Louis International Airport (STL)MKE - STL
3h 30m$255–455Bus
cheapest- Take the bus from Milwaukee Intermodal Station to Chicago Bus Station
- Take the bus from Chicago Bus Station to Des Moines
- Take the bus from Des Moines to Kansas City
13h 49m$84–257Train (Amtrak)
- Take the train from Milwaukee to Chicago Union StationHiawatha Service / ...
- Take the train from Chicago Union Station to Kansas CitySouthwest Chief / ...
10h 3m$88–221Drive 546.8 mi
- Drive from Milwaukee to Kansas City546.8 mi
9h 30m$100–145Fly General Mitchell International Airport to Kansas City
- Fly from General Mitchell International Airport (MKE) to Kansas City (MCI)MKE - MCI
4h 32m$282–652Bus to Chicago O'Hare International Airport, fly to Columbia Regional Airport
- Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departures
- Fly from Chicago O'Hare International Airport (ORD) to Columbia Regional Airport (COU)ORD - COU
4h 31m$125–383Bus to Chicago O'Hare International Airport, fly to Lambert–St. Louis International Airport
- Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departures
- Fly from Chicago O'Hare International Airport (ORD) to Lambert–St. Louis International Airport (STL)ORD - STL
4h 52m$208–541Bus to Chicago O'Hare International Airport, fly to Springfield-Branson National Airport
- Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departures
- Fly from Chicago O'Hare International Airport (ORD) to Springfield-Branson National Airport (SGF)ORD - SGF
4h 44m$101–358Train to Chicago Midway International Airport, fly to Lambert–St. Louis International Airport
- Take the train from Kenosha to Chicago OTC
- Fly from Chicago Midway International Airport (MDW) to Lambert–St. Louis International Airport (STL)MDW - STL
5h 34m$84–565
Wisconsin to Missouri by train and tram (Amtrak)
Questions & Answers
The cheapest way to get from Wisconsin to Missouri is to drive which costs $100 - $150 and takes 9h 30m.
The fastest way to get from Wisconsin to Missouri is to fly which takes 3h 30m and costs $250 - $460.
No, there is no direct bus from Wisconsin station to Missouri. However, there are services departing from Milwaukee Intermodal Station and arriving at Kansas City via Chicago Bus Station and Des Moines. The journey, including transfers, takes approximately 13h 49m.
No, there is no direct train from Wisconsin to Missouri. However, there are services departing from Milwaukee and arriving at Metro Center via Chicago Union Station and Union Station. The journey, including transfers, takes approximately 10h 3m.
The distance between Wisconsin and Missouri is 341 miles. The road distance is 550 miles.
The best way to get from Wisconsin to Missouri without a car is to train which takes 10h 3m and costs $85 - $230.
It takes approximately 3h 30m to get from Wisconsin to Missouri, including transfers.
Wisconsin to Missouri bus services, operated by Greyhound USA, depart from Milwaukee Intermodal Station.
Wisconsin to Missouri train services, operated by Amtrak, depart from Milwaukee station.
The best way to get from Wisconsin to Missouri is to fly which takes 3h 30m and costs $250 - $460. Alternatively, you can train, which costs $85 - $230 and takes 10h 3m, you could also bus, which costs $80 - $260 and takes 13h 49m.
What companies run services between Wisconsin, USA and Missouri, USA?
Southwest Airlines flies from General Mitchell International Airport (MKE) to Lambert–St. Louis International Airport (STL) twice daily. Alternatively, you can take a train from Milwaukee to Metro Center via Chicago Union Station, Kansas City, and Union Station in around 10h 3m.
- Website
- southwest.com
Flights from General Mitchell International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 22m
- When
- Every day
- Estimated price
- $120–800
Flights from General Mitchell International Airport to Lambert–St. Louis International Airport via Chicago Midway International Airport
- Ave. Duration
- 3h 10m
- When
- Monday and Friday
- Estimated price
- $120–800
Flights from General Mitchell International Airport to Kansas City
- Ave. Duration
- 1h 31m
- When
- Every day
- Estimated price
- $120–750
Flights from General Mitchell International Airport to Kansas City via Chicago Midway International Airport
- Ave. Duration
- 3h 57m
- When
- Monday, Thursday, and Friday
- Estimated price
- $130–800
Flights from Chicago Midway International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 14m
- When
- Every day
- Estimated price
- $75–550
- Website
- aa.com
Flights from Chicago O'Hare International Airport to Columbia Regional Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- $40–280
Flights from Chicago O'Hare International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 24m
- When
- Every day
- Estimated price
- $65–420
Flights from Chicago O'Hare International Airport to Springfield-Branson National Airport
- Ave. Duration
- 1h 50m
- When
- Every day
- Estimated price
- $50–300
- Website
- united.com
Flights from General Mitchell International Airport to Kansas City via Chicago O'Hare International Airport
- Ave. Duration
- 3h 54m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $130–800
Flights from Chicago O'Hare International Airport to Columbia Regional Airport
- Ave. Duration
- 1h 36m
- When
- Every day
- Estimated price
- $40–280
Flights from Chicago O'Hare International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 31m
- When
- Every day
- Estimated price
- $65–420
Flights from Chicago O'Hare International Airport to Springfield-Branson National Airport
- Ave. Duration
- 1h 55m
- When
- Every day
- Estimated price
- $50–300
- Website
- gojetairlines.com
Flights from Chicago O'Hare International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 28m
- When
- Every day
- Estimated price
- $65–420
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Milwaukee to Chicago Union Station
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- $22–45
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to Kansas City
- Ave. Duration
- 7h 23m
- Frequency
- Twice daily
- Estimated price
- $65–180
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 312-322-6777
- Website
- metra.com
Train from Kenosha to Chicago OTC
- Ave. Duration
- 1h 42m
- Frequency
- Every 3 hours
- Estimated price
- $3–7
- Website
- https://metra.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Milwaukee Intermodal Station to Chicago Bus Station
- Ave. Duration
- 1h 45m
- Frequency
- 3 times a day
- Estimated price
- $20–70
- Website
- https://www.greyhound.com/
Bus from Chicago Bus Station to Des Moines
- Ave. Duration
- 6h 34m
- Frequency
- 3 times a day
- Estimated price
- $45–100
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Milwaukee Intermodal Station to Chicago Bus Station
- Ave. Duration
- 2h 15m
- Frequency
- 3 times a day
- Estimated price
- $20–35
- Schedules at
- flixbus.com
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Des Moines to Kansas City
- Ave. Duration
- 3h 30m
- Frequency
- Twice daily
- Estimated price
- $18–90
- Book at
- https://www.jeffersonlines.com
- Phone
- (866) 912 6224
- questions@coachusa.com
- Website
- coachusa.com
Bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departures
- Ave. Duration
- 1h 50m
- Frequency
- Every 2 hours
- Estimated price
- $35–38
- Schedules at
- coachusa.com
Want to know more about travelling around United States
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More Questions & Answers
Wisconsin to Missouri bus services, operated by Greyhound USA, arrive at Chicago Bus Station.
Wisconsin to Missouri train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between Wisconsin to Missouri is 550 miles. It takes approximately 9h 30m to drive from Wisconsin to Missouri.
There are 341+ hotels available in Missouri.













