There are 9 ways to get from Wisconsin to Missouri by plane, train (Amtrak), bus (Greyhound, Flixbus), car, bus, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly General Mitchell International Airport to Lambert–St. Louis International Airport
best- Fly from General Mitchell International Airport (MKE) to Lambert–St. Louis International Airport (STL)plane MKE - STL
3h 28m$135–955Bus
cheapest- Take the bus from Milwaukee Intermodal Station to Chicago Bus Stationbus
- Take the bus from Chicago Bus Station to St Louis Bus Stationbus
- Take the bus from St Louis Bus Station to Kansas City Bus Stationbus
13h 40m$92–177Train (Amtrak)
- Take the train from Milwaukee to Chicago Union Stationtrain Hiawatha Service / ...
- Take the train from Chicago Union Station to Kansas Citytrain Southwest Chief / ...
10h 4m$133–310Drive 546.8 mi
- Drive from Milwaukee to Kansas Citycar 546.8 mi
9h 34m$100–145Bus to Chicago O'Hare International Airport, fly to Lambert–St. Louis International Airport
- Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus
- Fly from Chicago O'Hare International Airport (ORD) to Lambert–St. Louis International Airport (STL)plane ORD - STL
4h 49m$301–594Bus to Chicago O'Hare International Airport, fly to Columbia Regional Airport
- Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus
- Fly from Chicago O'Hare International Airport (ORD) to Columbia Regional Airport (COU)plane ORD - COU
4h 37m$128–376Fly General Mitchell International Airport to Kansas City
- Fly from General Mitchell International Airport (MKE) to Kansas City (MCI)plane MKE - MCI
4h 35m$132–852Bus to Chicago O'Hare International Airport, fly to Springfield-Branson National Airport
- Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus
- Fly from Chicago O'Hare International Airport (ORD) to Springfield-Branson National Airport (SGF)plane ORD - SGF
4h 52m$99–361Train to Chicago Midway International Airport, fly to Lambert–St. Louis International Airport
- Take the train from Kenosha to Chicago OTCtrain
- Fly from Chicago Midway International Airport (MDW) to Lambert–St. Louis International Airport (STL)plane MDW - STL
5h 34m$97–666
Wisconsin to Missouri by train and tram (Amtrak)
Questions & Answers
The cheapest way to get from Wisconsin to Missouri is to bus which costs $90 - $180 and takes 13h 40m.
The fastest way to get from Wisconsin to Missouri is to fly which takes 3h 28m and costs $130 - $1,000.
No, there is no direct bus from Wisconsin station to Missouri station. However, there are services departing from Milwaukee Intermodal Station and arriving at Kansas City Bus Station via Chicago Bus Station and St Louis Bus Station. The journey, including transfers, takes approximately 13h 40m.
No, there is no direct train from Wisconsin to Missouri. However, there are services departing from Milwaukee and arriving at Metro Center via Chicago Union Station and Union Station. The journey, including transfers, takes approximately 10h 4m.
The distance between Wisconsin and Missouri is 341 miles. The road distance is 550 miles.
The best way to get from Wisconsin to Missouri without a car is to train which takes 10h 4m and costs $130 - $310.
It takes approximately 3h 28m to get from Wisconsin to Missouri, including transfers.
Wisconsin to Missouri bus services, operated by Greyhound USA, depart from Milwaukee Intermodal Station.
Wisconsin to Missouri train services, operated by Amtrak, depart from Milwaukee station.
The best way to get from Wisconsin to Missouri is to fly which takes 3h 28m and costs $130 - $1,000. Alternatively, you can train, which costs $130 - $310 and takes 10h 4m, you could also bus, which costs $90 - $180 and takes 13h 40m.
What companies run services between Wisconsin, USA and Missouri, USA?
Southwest Airlines, United Airlines, and American Airlines fly from General Mitchell International Airport (MKE) to Lambert–St. Louis International Airport (STL) every 4 hours. Alternatively, you can take a train from Milwaukee to Metro Center via Chicago Union Station, Kansas City, and Union Station in around 10h 4m.
- Website
- southwest.com
Flights from General Mitchell International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- $130–950
Flights from General Mitchell International Airport to Lambert–St. Louis International Airport via Chicago Midway International Airport
- Ave. Duration
- 3h 32m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $140–950
Flights from General Mitchell International Airport to Kansas City
- Ave. Duration
- 1h 31m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $130–850
Flights from General Mitchell International Airport to Kansas City via Lambert–St. Louis International Airport
- Ave. Duration
- 3h 15m
- When
- Sunday
- Estimated price
- $150–900
Flights from Chicago Midway International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 14m
- When
- Every day
- Estimated price
- $85–650
- Website
- united.com
Flights from General Mitchell International Airport to Lambert–St. Louis International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 3h 34m
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $140–950
Flights from Chicago O'Hare International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 31m
- When
- Every day
- Estimated price
- $65–460
Flights from Chicago O'Hare International Airport to Columbia Regional Airport
- Ave. Duration
- 1h 38m
- When
- Every day
- Estimated price
- $40–270
Flights from Chicago O'Hare International Airport to Springfield-Branson National Airport
- Ave. Duration
- 1h 53m
- When
- Every day
- Estimated price
- $45–300
- Website
- aa.com
Flights from General Mitchell International Airport to Lambert–St. Louis International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 3h 37m
- When
- Every day
- Estimated price
- $140–950
Flights from Chicago O'Hare International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 24m
- When
- Every day
- Estimated price
- $65–460
Flights from Chicago O'Hare International Airport to Columbia Regional Airport
- Ave. Duration
- 1h 32m
- When
- Every day
- Estimated price
- $40–270
Flights from Chicago O'Hare International Airport to Springfield-Branson National Airport
- Ave. Duration
- 1h 53m
- When
- Every day
- Estimated price
- $45–300
- Website
- gojetairlines.com
Flights from Chicago O'Hare International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 36m
- When
- Every day
- Estimated price
- $65–460
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Milwaukee to Chicago Union Station
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- $23–50
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to Kansas City
- Ave. Duration
- 7h 23m
- Frequency
- Twice daily
- Estimated price
- $110–260
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 312-696-3872
- Website
- metra.com
Train from Kenosha to Chicago OTC
- Ave. Duration
- 1h 42m
- Frequency
- Every 3 hours
- Estimated price
- $6–8
- Website
- https://metra.com
- Adult
- $6–8
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Milwaukee Intermodal Station to Chicago Bus Station
- Ave. Duration
- 1h 45m
- Frequency
- 4 times a day
- Estimated price
- $14–28
- Website
- https://www.greyhound.com/
Bus from St Louis Bus Station to Kansas City Bus Station
- Ave. Duration
- 4h
- Frequency
- 4 times a day
- Estimated price
- $40–80
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Milwaukee Intermodal Station to Chicago Bus Station
- Ave. Duration
- 1h 50m
- Frequency
- 3 times a day
- Estimated price
- $11–20
- Schedules at
- flixbus.com
Bus from Chicago Bus Station to St Louis Bus Station
- Ave. Duration
- 5h 55m
- Frequency
- 3 times a day
- Estimated price
- $40–70
- Schedules at
- flixbus.com
- Phone
- (866) 912 6224
- questions@coachusa.com
- Website
- coachusa.com
Bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departures
- Ave. Duration
- 1h 50m
- Frequency
- Hourly
- Estimated price
- $38–42
- Website
- https://www.coachusa.com/wisconsin-coach?gad_source=1&gclid=CjwKCAiAt4C-BhBcEiwA8Kp0Cc3RRg_kOdc3CzsoiFSe4BX-r10-kIOeuDNMfsAKsG5uubvoAmxcrRoC5LwQAvD_BwE
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More Questions & Answers
Wisconsin to Missouri bus services, operated by Greyhound USA, arrive at Chicago Bus Station.
Wisconsin to Missouri train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between Wisconsin to Missouri is 550 miles. It takes approximately 9h 34m to drive from Wisconsin to Missouri.
Book your Wisconsin to Missouri bus tickets online with Omio and FlixBus.
There are 1294+ hotels available in Missouri.









