There are 8 ways to get from Wisconsin to Des Moines by plane, bus (Greyhound, Flixbus), car, bus, train, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from General Mitchell International Airport
best- Fly from General Mitchell International Airport (MKE) to Des Moines (DSM)MKE - DSM
5h 36m$169–973Drive 354.8 mi
cheapest- Drive from Milwaukee to Des Moines354.8 mi
6h 21m$65–94Bus
- Take the bus from Milwaukee Intermodal Station to Chicago Bus StationGreyhound US0150S / ...
- Take the bus from Chicago to Des MoinesChicago
9h 55m$76–227Bus to Chicago O'Hare International Airport, fly
- Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departures
- Fly from Chicago O'Hare International Airport (ORD) to Des Moines (DSM)ORD - DSM
4h 25m$132–559Bus to Minneapolis–Saint Paul International Airport, fly
- Take the bus from Eau Claire Amtrak Bus Stop to Mall of America - IKEA - Bloomington
- Fly from Minneapolis–Saint Paul International Airport (MSP) to Des Moines (DSM)MSP - DSM
4h 54m$145–759Train to Chicago Midway International Airport, fly
- Take the train from Kenosha to Chicago OTC
- Fly from Chicago Midway International Airport (MDW) to Des Moines (DSM)MDW - DSM
5h 18m$118–683Bus via Chicago O'Hare Airport (ORD)
- Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 DeparturesWisconsin Coach Lines
- Take the bus from Chicago Bus Station to Des MoinesGreyhound US0123 / ...
10h 14m$82–143Train, bus
- Take the train from Milwaukee to Chicago Union Station
- Take the train from Chicago Union Station to Galesburg Amtrak Station
- Take the bus from Galesburg to Burlington
- Take the bus from Burlington to Des Moines
11h 20m$117–271
Wisconsin to Des Moines by bus
Questions & Answers
The cheapest way to get from Wisconsin to Des Moines is to drive which costs $65 - $95 and takes 6h 21m.
The fastest way to get from Wisconsin to Des Moines is to bus and fly which takes 4h 25m and costs $130 - $600.
No, there is no direct bus from Wisconsin station to Des Moines. However, there are services departing from Milwaukee Intermodal Station and arriving at Des Moines via Chicago. The journey, including transfers, takes approximately 9h 55m.
The distance between Wisconsin and Des Moines is 325 miles. The road distance is 356.9 miles.
The best way to get from Wisconsin to Des Moines without a car is to bus which takes 9h 55m and costs $75 - $230.
It takes approximately 5h 36m to get from Wisconsin to Des Moines, including transfers.
Wisconsin to Des Moines bus services, operated by Greyhound USA, depart from Milwaukee Intermodal Station.
The best way to get from Wisconsin to Des Moines is to fly which takes 5h 36m and costs $160 - $1,000. Alternatively, you can bus, which costs $75 - $230 and takes 9h 55m.
Wisconsin to Des Moines bus services, operated by Greyhound USA, arrive at Chicago Bus Station.
Yes, the driving distance between Wisconsin to Des Moines is 357 miles. It takes approximately 6h 21m to drive from Wisconsin to Des Moines.
What companies run services between Wisconsin, USA and Des Moines, IA, USA?
United Airlines, Delta, and two other airlines fly from General Mitchell International Airport (MKE) to Des Moines (DSM) hourly. Alternatively, you can take a bus from Milwaukee Intermodal Station to Des Moines via Chicago in around 9h 55m.
- Website
- aa.com
Flights from General Mitchell International Airport to Des Moines via Chicago O'Hare International Airport
- Ave. Duration
- 4h 36m
- When
- Every day
- Estimated price
- $150–950
Flights from Chicago O'Hare International Airport to Des Moines
- Ave. Duration
- 1h 31m
- When
- Every day
- Estimated price
- $80–500
- Website
- delta.com
Flights from General Mitchell International Airport to Des Moines via Minneapolis–Saint Paul International Airport
- Ave. Duration
- 4h 51m
- When
- Every day
- Estimated price
- $180–1,100
Flights from General Mitchell International Airport to Des Moines via Atlanta
- Ave. Duration
- 7h 10m
- When
- Monday, Tuesday, Friday, Saturday, and Sunday
- Estimated price
- $330–1,500
Flights from General Mitchell International Airport to Des Moines via Detroit
- Ave. Duration
- 7h 29m
- When
- Every day
- Estimated price
- $220–1,200
Flights from Minneapolis–Saint Paul International Airport to Des Moines
- Ave. Duration
- 1h 23m
- When
- Every day
- Estimated price
- $100–700
- Website
- united.com
Flights from General Mitchell International Airport to Des Moines via Chicago O'Hare International Airport
- Ave. Duration
- 5h 4m
- When
- Every day
- Estimated price
- $150–950
Flights from General Mitchell International Airport to Des Moines via Denver
- Ave. Duration
- 7h 52m
- When
- Every day
- Estimated price
- $340–1,600
Flights from Chicago O'Hare International Airport to Des Moines
- Ave. Duration
- 1h 36m
- When
- Every day
- Estimated price
- $80–500
- Website
- southwest.com
Flights from General Mitchell International Airport to Des Moines via Denver
- Ave. Duration
- 5h 50m
- When
- Monday, Tuesday, Friday, Saturday, and Sunday
- Estimated price
- $340–1,600
Flights from General Mitchell International Airport to Des Moines via St. Louis
- Ave. Duration
- 5h 27m
- When
- Wednesday and Thursday
- Estimated price
- $190–1,100
Flights from General Mitchell International Airport to Des Moines via Chicago Midway International Airport
- Ave. Duration
- 6h 20m
- When
- Monday, Thursday, and Friday
- Estimated price
- $150–950
Flights from Chicago Midway International Airport to Des Moines
- Ave. Duration
- 1h 25m
- When
- Monday, Thursday, and Friday
- Estimated price
- $95–650
Flights from Chicago Midway International Airport to Des Moines via St. Louis
- Ave. Duration
- 3h 40m
- When
- Saturday
- Estimated price
- $120–700
- Phone
- +1 312-322-6777
- Website
- metra.com
Train from Kenosha to Chicago OTC
- Ave. Duration
- 1h 42m
- Frequency
- Every 3 hours
- Estimated price
- $3–7
- Website
- https://metra.com
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Milwaukee to Chicago Union Station
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- $22–45
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to Galesburg Amtrak Station
- Ave. Duration
- 2h 36m
- Frequency
- 4 times a day
- Estimated price
- $30–100
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Milwaukee Intermodal Station to Chicago Bus Station
- Ave. Duration
- 1h 45m
- Frequency
- 3 times a day
- Estimated price
- $20–70
- Website
- https://www.greyhound.com/
Bus from Chicago Bus Station to Des Moines
- Ave. Duration
- 6h 34m
- Frequency
- 3 times a day
- Estimated price
- $45–100
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Milwaukee Intermodal Station to Chicago Bus Station
- Ave. Duration
- 2h 15m
- Frequency
- 3 times a day
- Estimated price
- $20–35
- Schedules at
- flixbus.com
- Phone
- +1 (319) 753-2864
- info@burlingtontrailways.com
- Website
- burlingtontrailways.com
Bus from Chicago to Des Moines
- Ave. Duration
- 7h 10m
- Frequency
- Twice daily
- Estimated price
- $55–160
- Website
- https://burlingtontrailways.com
- Saver Fares
- $65–95
- Flexible Fares
- $90–130
- Saver Fare
- $55–110
- Flex Fare
- $75–160
Bus from Galesburg to Burlington
- Ave. Duration
- 1h 10m
- Frequency
- Once daily
- Estimated price
- $25–50
- Website
- https://burlingtontrailways.com
- Saver Fares
- $25–40
- Flexible Fares
- $30–50
Bus from Burlington to Des Moines
- Ave. Duration
- 3h 5m
- Frequency
- Once daily
- Estimated price
- $40–80
- Website
- https://burlingtontrailways.com
- Saver Fares
- $40–60
- Flexible Fares
- $50–80
- Phone
- (866) 912 6224
- questions@coachusa.com
- Website
- coachusa.com
Bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departures
- Ave. Duration
- 1h 50m
- Frequency
- Every 2 hours
- Estimated price
- $35–38
- Schedules at
- coachusa.com
- Phone
- +1 414-266-4409
- ticketinfo@badgerbus.com
- Website
- badgerbus.com
Bus from Eau Claire Amtrak Bus Stop to Mall of America - IKEA - Bloomington
- Ave. Duration
- 1h 50m
- Frequency
- Twice a week
- Estimated price
- $26–35
- Website
- https://badgerbus.com
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