There are 10 ways to get from Wisconsin to Des Moines by bus, plane, bus (Greyhound, Flixbus), train, car, or bus (Flixbus, Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus to Chicago O'Hare International Airport, fly to Des Moines
best- Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus
- Fly from Chicago O'Hare International Airport (ORD) to Des Moines (DSM)plane ORD - DSM
4h 26m$96–334Drive 354.8 mi
cheapest- Drive from Milwaukee to Des Moinescar 354.8 mi
6h 23m$65–94Bus
- Take the bus from Milwaukee Intermodal Station to Chicago Bus Stationbus Greyhound US0150
- Take the bus from Chicago Bus Station to Des Moinesbus Greyhound US0123S / ...
9h 5m$69–113Train, bus via Saint Paul
- Take the train from Milwaukee to St. Paul-Minneapolistrain Borealis / ...
- Take the bus from Saint Paul Union Depot to Des Moinesbus Greyhound US0156
11h 22m$219–340Bus to Minneapolis–Saint Paul International Airport, fly to Des Moines
- Take the bus from Eau Claire Amtrak Bus Stop to Mall of America - IKEA - Bloomingtonbus
- Fly from Minneapolis–Saint Paul International Airport (MSP) to Des Moines (DSM)plane MSP - DSM
4h 37m$97–433Train to Chicago Midway International Airport, fly to Des Moines
- Take the train from Kenosha to Chicago OTCtrain
- Fly from Chicago Midway International Airport (MDW) to Des Moines (DSM)plane MDW - DSM
5h 12m$87–436Bus to Chicago O'Hare International Airport, fly to Fort Dodge Municipal Airport, drive
- Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus
- Fly from Chicago O'Hare International Airport (ORD) to Fort Dodge Municipal Airport (FOD)plane ORD - FOD
- Drive from Fort Dodge Municipal Airport (FOD) to Des Moinescar
6h 15m$94–336Train, bus
- Take the train from Milwaukee to Chicago Union Stationtrain Hiawatha Service / ...
- Take the bus from Chicago Bus Station to Des Moinesbus Greyhound US0123S / ...
9h 8m$102–162Bus via Airport
- Take the bus from Milwaukee Mitchell Airport to Chicago Bus Stationbus FlixBus 2548 / ...
- Take the bus from Chicago Bus Station to Des Moinesbus Greyhound US0123S / ...
10h 52m$69–111Train, bus #2
- Take the train from Milwaukee to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Galesburg Amtrak Stationtrain
- Take the bus from Galesburg to Des Moinesbus
11h$167–267
Wisconsin to Des Moines by bus
Comparing Your Travel Options
The cheapest way to get from Wisconsin to Des Moines is to drive which costs $65 - $95 and takes 6h 23m.
The fastest way to get from Wisconsin to Des Moines is to bus and fly which takes 4h 26m and costs $95 - $340.
No, there is no direct bus from Wisconsin station to Des Moines. However, there are services departing from Milwaukee Intermodal Station and arriving at Des Moines via Chicago Bus Station. The journey, including transfers, takes approximately 9h 5m.
The distance between Wisconsin and Des Moines is 388 miles. The road distance is 356.9 miles.
The best way to get from Wisconsin to Des Moines without a car is to bus which takes 9h 5m and costs $65 - $120.
It takes approximately 4h 26m to get from Wisconsin to Des Moines, including transfers.
Wisconsin to Des Moines bus services, operated by Greyhound USA, depart from Milwaukee Intermodal Station.
Wisconsin to Des Moines bus services, operated by Greyhound USA, arrive at Chicago Bus Station.
Yes, the driving distance between Wisconsin to Des Moines is 357 miles. It takes approximately 6h 23m to drive from Wisconsin to Des Moines.
Book your Wisconsin to Des Moines bus tickets online with Omio and FlixBus.
What companies run services between Wisconsin, USA and Des Moines, IA, USA?
You can take a bus from Milwaukee Intermodal Station to Des Moines via Chicago Bus Station in around 9h 5m.
- Website
- united.com
Flights from Chicago O'Hare International Airport to Des Moines
- Ave. Duration
- 1h 31m
- When
- Every day
- Estimated price
- $40–270
Flights from Chicago O'Hare International Airport to Fort Dodge Municipal Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- $40–270
- Website
- southwest.com
Flights from Chicago Midway International Airport to Des Moines
- Ave. Duration
- 1h 24m
- When
- Every day
- Estimated price
- $60–400
- Website
- aa.com
Flights from Chicago O'Hare International Airport to Des Moines
- Ave. Duration
- 1h 37m
- When
- Every day
- Estimated price
- $40–270
- Website
- delta.com
Flights from Minneapolis–Saint Paul International Airport to Des Moines
- Ave. Duration
- 1h 16m
- When
- Every day
- Estimated price
- $50–370
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Milwaukee to St. Paul-Minneapolis
- Ave. Duration
- 5h 52m
- Frequency
- 3 times a day
- Estimated price
- $170–280
- Website
- Amtrak
Train from Milwaukee to Chicago Union Station
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- $45–75
- Website
- Amtrak
Train from Milwaukee to Chicago Union Station
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- $45–75
- Website
- Amtrak
Train from Chicago Union Station to Galesburg Amtrak Station
- Ave. Duration
- 2h 36m
- Frequency
- 4 times a day
- Estimated price
- $85–140
- Website
- Amtrak
- Phone
- +1 312-696-3872
- Website
- Metra
Train from Kenosha to Chicago OTC
- Ave. Duration
- 1h 42m
- Frequency
- Every 3 hours
- Estimated price
- $6–8
- Website
- Metra
- Adult
- $6–8
- Phone
- (866) 912 6224
- questions@coachusa.com
- Website
- coachusa.com
Bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departures
- Ave. Duration
- 1h 50m
- Frequency
- Hourly
- Estimated price
- $38–42
- Website
- coachusa.com
Bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departures
- Ave. Duration
- 1h 50m
- Frequency
- Hourly
- Estimated price
- $38–42
- Website
- coachusa.com
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- Greyhound
Bus from Milwaukee Intermodal Station to Chicago Bus Station
- Ave. Duration
- 1h 35m
- Frequency
- 4 times a day
- Estimated price
- $15–23
- Website
- Greyhound
Bus from Chicago Bus Station to Des Moines
- Ave. Duration
- 6h 30m
- Frequency
- 3 times a day
- Estimated price
- $55–90
- Website
- Greyhound
Bus from Saint Paul Union Depot to Des Moines
- Ave. Duration
- 4h 30m
- Frequency
- Once daily
- Estimated price
- $40–65
- Website
- Greyhound
Bus from Chicago Bus Station to Des Moines
- Ave. Duration
- 6h 30m
- Frequency
- 3 times a day
- Estimated price
- $55–90
- Website
- Greyhound
Bus from Chicago Bus Station to Des Moines
- Ave. Duration
- 6h 30m
- Frequency
- 3 times a day
- Estimated price
- $55–90
- Website
- Greyhound
Bus from Galesburg to Des Moines
- Ave. Duration
- 4h 55m
- Frequency
- Once daily
- Estimated price
- $35–55
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Milwaukee Intermodal Station to Chicago Bus Station
- Ave. Duration
- 2h 15m
- Frequency
- 3 times a day
- Estimated price
- $13–21
- Schedules at
- Flixbus USA
Bus from Milwaukee Mitchell Airport to Chicago Bus Station
- Ave. Duration
- 1h 55m
- Frequency
- 3 times a day
- Estimated price
- $12–19
- Schedules at
- Flixbus USA
- Phone
- +1 414-266-4409
- ticketinfo@badgerbus.com
- Website
- Badger Bus
Bus from Eau Claire Amtrak Bus Stop to Mall of America - IKEA - Bloomington
- Ave. Duration
- 1h 50m
- Frequency
- Twice a week
- Estimated price
- $26–35
- Website
- Badger Bus
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Booking & Getting There
There are 196+ hotels available in Des Moines.










