There are 8 ways to get from Wiscasset to Hyannis by bus (Amtrak), train, bus, car, plane, or taxi
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Amtrak Thruway, bus via Boston
best- Take the bus from Wiscasset to South StationBangor
- Take the bus from Boston South Buses to Hyannis Transportation CenterHyannis - South Shore to Logan Airport
6h 12m$67–95Drive 220.2 mi
cheapest- Drive from Wiscasset to Hyannis220.2 mi
4h 10m$41–58Train, bus
- Take the train from Brunswick Amtrak Station to BostonDowneaster
- Take the bus from Boston South Station to Hyannis Transportation CenterBoston
6h 39m$114–159Fly Augusta State Airport to Barnstable Municipal Airport
- Fly from Augusta State Airport (AUG) to Barnstable Municipal Airport (HYA)AUG - HYA
6h 55m$226–582Amtrak Thruway, bus
- Take the bus from Wiscasset to South StationBangor
- Take the bus from Boston South Station to Hyannis Transportation CenterBoston
6h 15m$50–100Bus
- Take the bus from Wiscasset to Portland Transportation Center
- Take the bus from Portland, ME to Logan International Airport
- Take the bus from Logan International Airport to Hyannis Transportation Center
6h 39m$71–130Fly Augusta State Airport to Boston Logan Airport, bus
- Fly from Augusta State Airport (AUG) to Boston Logan Airport (BOS)AUG - BOS
- Take the bus from Logan International Airport to Hyannis Transportation Center
4h 53m$196–249Taxi to Rockland, fly to Boston Logan Airport, bus
- Take the taxi from Wiscasset to Rockland (RKD)
- Fly from Rockland (RKD) to Boston Logan Airport (BOS)RKD - BOS
- Take the bus from Logan International Airport to Hyannis Transportation Center
5h 8m$270–384
Augusta State Airport (AUG) to Barnstable Municipal Airport (HYA) flights
Questions & Answers
The cheapest way to get from Wiscasset to Hyannis is to drive which costs $40 - $60 and takes 4h 10m.
The fastest way to get from Wiscasset to Hyannis is to drive which takes 4h 10m and costs $40 - $60.
The distance between Wiscasset and Hyannis is 226 miles. The road distance is 221.5 miles.
The best way to get from Wiscasset to Hyannis without a car is to Amtrak Thruway and bus via Boston which takes 6h 12m and costs $65 - $95.
It takes approximately 6h 12m to get from Wiscasset to Hyannis, including transfers.
The best way to get from Wiscasset to Hyannis is to Amtrak Thruway and bus via Boston which takes 6h 12m and costs $65 - $95. Alternatively, you can fly, which costs $220 - $600 and takes 6h 55m.
Yes, the driving distance between Wiscasset to Hyannis is 221 miles. It takes approximately 4h 10m to drive from Wiscasset to Hyannis.
There are 819+ hotels available in Hyannis.
What companies run services between Wiscasset, ME, USA and Hyannis, MA, USA?
You can take a vehicle from Wiscasset to Hyannis Transportation Center via Wiscasset, South Station, and Boston South Buses in around 6h 12m. Alternatively, Cape Air flies from Augusta State Airport (AUG) to Barnstable Municipal Airport (HYA) twice daily.
Transport is disrupted due to the Russia-Ukraine war. Read more
- Website
- capeair.com
Flights from Augusta State Airport to Barnstable Municipal Airport via Boston Logan Airport
- Ave. Duration
- 6h 37m
- When
- Every day
- Estimated price
- $140–480
Flights from Augusta State Airport to Barnstable Municipal Airport via Boston Logan Airport, Nantucket
- Ave. Duration
- 6h 11m
- When
- Sunday
- Estimated price
- $160–550
Flights from Augusta State Airport to Barnstable Municipal Airport via Boston Logan Airport, Martha's Vineyard
- Ave. Duration
- 8h 10m
- When
- Friday
- Estimated price
- $150–550
Flights from Augusta State Airport to Boston Logan Airport
- Ave. Duration
- 1h 26m
- When
- Every day
- Estimated price
- $85–110
Flights from Rockland to Boston Logan Airport
- Ave. Duration
- 1h 28m
- When
- Every day
- Estimated price
- $120–200
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Brunswick Amtrak Station to Boston
- Ave. Duration
- 3h 20m
- Frequency
- Every 4 hours
- Estimated price
- $37–41
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Amtrak Thruway
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Wiscasset to South Station
- Ave. Duration
- 3h 35m
- Frequency
- Once daily
- Estimated price
- $28–45
- Website
- https://www.amtrak.com/home.html
- Adult
- $28–45
Bus from Wiscasset to Portland Transportation Center
- Ave. Duration
- 1h 40m
- Frequency
- Once daily
- Estimated price
- $10–45
- Website
- https://www.amtrak.com/home.html
- Adult
- $10–45
- Phone
- +1 800 639 3317
- info@concordcoachlines.com
- Website
- concordcoachlines.com
Bus from Wiscasset to South Station
- Ave. Duration
- 3h 35m
- Frequency
- Once daily
- Estimated price
- $30–45
- Website
- https://concordcoachlines.com
Bus from Wiscasset to Portland Transportation Center
- Ave. Duration
- 1h 10m
- Frequency
- Once daily
- Estimated price
- $9–13
- Website
- https://concordcoachlines.com
Bus from Portland, ME to Logan International Airport
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- $22–30
- Website
- https://concordcoachlines.com
- Phone
- +1 (508) 746-0378
- info@p-b.com
- Website
- p-b.com
Bus from Boston South Buses to Hyannis Transportation Center
- Ave. Duration
- 1h 50m
- Frequency
- Hourly
- Estimated price
- $27–35
- Website
- https://www.p-b.com
- One Way - Adult
- $27–35
Bus from Logan International Airport to Hyannis Transportation Center
- Ave. Duration
- 2h 15m
- Frequency
- Hourly
- Estimated price
- $28–40
- Website
- https://www.p-b.com
- One Way - Adult
- $28–40
- Phone
- 1-800-343-9999
- Website
- peterpanbus.com
Bus from Boston South Station to Hyannis Transportation Center
- Ave. Duration
- 1h 35m
- Frequency
- Every 3 hours
- Estimated price
- $10–40
- Website
- https://peterpanbus.com
- Adult
- $10–40
- Ave. Duration
- 49 min
- Estimated price
- $120–150
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide













