From Wicklow Train Station train to Wexford, Wexford Station then bus to Waterford, Clock Tower The Quay. 3 h 14 min 37€. From Wicklow, Wicklow Grand Hotel bus to Dublin, walk to Dublin City South, Burgh Quay, then bus to Days Hotel Merchants Quay Waterford. 4 h 32 min 21€. From Wicklow drive to Waterford. 1 h 31 min 17€.
No, there is no direct bus from Wicklow to Waterford. However, there are services departing from Wicklow, Wicklow Grand Hotel and arriving at Days Hotel Merchants Quay Waterford via Dublin City South, Burgh Quay. The journey, including transfers, takes approximately 4 h 32 min.