There are 10 ways to get from Wetzlar to Rome by train, plane, train (Trenitalia), bus, night train, car, or car train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train to Frankfurt, fly to Fiumicino International Airport
best- Take the train from Wetzlar Bahnhof to Frankfurttrain
- Fly from Frankfurt (FRA) to Fiumicino International Airport (FCO)plane FRA - FCO
5h 41m€74–208Train
- Take the train from Wetzlar Bahnhof to Frankfurttrain 34
- Take the train from Frankfurt to Basel SBBtrain 20 / ...
- Take the train from Basel SBB to Luganotrain Ec
- Take the train from Lugano to Milano Centraletrain
- Take the train from Milano Centrale to Roma Terminitrain Fr / ...
13h 48m€221–460Train, bus
- Take the train from Gießen Bahnhof to Frankfurttrain Re30
- Take the bus from Frankfurt central train station to Roma, Autostazione Tiburtinabus N77
23h 21m€93–168Train, night train
- Take the train from Gießen Bahnhof to Frankfurttrain
- Take the train from Frankfurt to München Hbftrain 41 / ...
- Take the night train from Muenchen Hbf to Roma Tiburtinanighttrain Nj
20h 53m€153–383Train, train to Cologne Bonn Airport, fly to Fiumicino International Airport
- Take the train from Wetzlar Bahnhof to Siegen Hbftrain
- Take the train from Siegen Hbf to Troisdorf Bftrain
- Fly from Cologne Bonn Airport (CGN) to Fiumicino International Airport (FCO)plane CGN - FCO
7h 24m€104–275Train, train to Stuttgart Airport, fly to Fiumicino International Airport
- Take the train from Wetzlar Bahnhof to Frankfurttrain
- Take the train from Frankfurt to Hauptbahnhoftrain
- Fly from Stuttgart Airport (STR) to Fiumicino International Airport (FCO)plane STR - FCO
7h 34m€137–302Train to Frankfurt, fly to Florence Peretola Airport, train
- Take the train from Wetzlar Bahnhof to Frankfurttrain
- Fly from Frankfurt (FRA) to Florence Peretola Airport (FLR)plane FRA - FLR
- Take the train from Firenze Santa Maria Novella to Roma Terminitrain
7h 11m€178–394Train, train to Düsseldorf International Airport, fly to Fiumicino International Airport
- Take the train from Wetzlar Bahnhof to Siegen Hbftrain
- Take the train from Siegen Hbf to Köln Messe/Deutz Bftrain
- Take the train from Koeln Messe/Deutz to Duesseldorf Flughafentrain
- Fly from Düsseldorf International Airport (DUS) to Fiumicino International Airport (FCO)plane DUS - FCO
8h 30m€122–267Drive 1,288.5 km
- Drive from Wetzlar to Romecar 1,288.5 km
12h 2m€199–287Drive, car train
- Drive from Wetzlar to Fuldacar
- Take the car train from Fulda to Villach Hbfcartrain
- Drive from Villach Hbf to Romecar
13h 14m€224–1,000
Wetzlar to Rome by train
Questions & Answers
The cheapest way to get from Wetzlar to Rome is to train and fly which costs €70 - €210 and takes 5h 41m.
The fastest way to get from Wetzlar to Rome is to train and fly which takes 5h 41m and costs €70 - €210.
No, there is no direct train from Wetzlar to Rome. However, there are services departing from Wetzlar Bahnhof and arriving at Roma Termini via Frankfurt, Basel SBB, Lugano and Milano Centrale. The journey, including transfers, takes approximately 13h 48m.
The distance between Wetzlar and Rome is 1078 km. The road distance is 1288.5 km.
The best way to get from Wetzlar to Rome without a car is to train which takes 13h 48m and costs €220 - €460.
It takes approximately 5h 41m to get from Wetzlar to Rome, including transfers.
Wetzlar to Rome train services, operated by Deutsche Bahn Intercity (DB IC), depart from Wetzlar Bahnhof station.
Wetzlar to Rome train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Frankfurt station.
Yes, the driving distance between Wetzlar to Rome is 1288 km. It takes approximately 12h 2m to drive from Wetzlar to Rome.
Book your Wetzlar to Rome train tickets online with Omio.
What companies run services between Wetzlar, Germany and Rome, Italy?
You can take a train from Wetzlar Bahnhof to Roma Termini via Frankfurt, Basel SBB, Lugano, and Milano Centrale in around 13h 48m.
- Website
- lufthansa.com
Flights from Frankfurt to Fiumicino International Airport
- Ave. Duration
- 1h 52m
- When
- Every day
- Estimated price
- €65–360
Flights from Frankfurt to Fiumicino International Airport via Munich
- Ave. Duration
- 3h 51m
- When
- Every day
- Estimated price
- €45–260
Flights from Frankfurt to Fiumicino International Airport via Venice
- Ave. Duration
- 3h 45m
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €80–190
Flights from Cologne Bonn Airport to Fiumicino International Airport via Munich
- Ave. Duration
- 3h 51m
- When
- Every day
- Estimated price
- €90–290
Flights from Stuttgart Airport to Fiumicino International Airport via Munich
- Ave. Duration
- 3h 55m
- When
- Monday to Saturday
- Estimated price
- €80–330
Flights from Frankfurt to Florence Peretola Airport
- Ave. Duration
- 1h 36m
- When
- Every day
- Estimated price
- €100–360
Flights from Frankfurt to Florence Peretola Airport via Munich
- Ave. Duration
- 3h 18m
- When
- Every day
- Estimated price
- €110–360
Flights from Düsseldorf International Airport to Fiumicino International Airport via Munich
- Ave. Duration
- 4h 26m
- When
- Every day
- Estimated price
- €75–320
- Website
- ita-airways.com
Flights from Frankfurt to Fiumicino International Airport
- Ave. Duration
- 1h 52m
- When
- Every day
- Estimated price
- €65–360
Flights from Frankfurt to Fiumicino International Airport via Milan Linate
- Ave. Duration
- 3h 30m
- When
- Monday to Friday
- Estimated price
- €80–190
Flights from Frankfurt to Fiumicino International Airport via Venice
- Ave. Duration
- 3h 42m
- When
- Every day
- Estimated price
- €80–190
Flights from Cologne Bonn Airport to Fiumicino International Airport
- Ave. Duration
- 1h 55m
- When
- Monday, Wednesday, Friday, and Sunday
- Estimated price
- €65–200
Flights from Stuttgart Airport to Fiumicino International Airport
- Ave. Duration
- 1h 40m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €65–180
Flights from Stuttgart Airport to Fiumicino International Airport via Milan Linate
- Ave. Duration
- 3h 50m
- When
- Monday to Friday
- Estimated price
- €130–270
Flights from Frankfurt to Florence Peretola Airport
- Ave. Duration
- 1h 36m
- When
- Every day
- Estimated price
- €100–360
Flights from Düsseldorf International Airport to Fiumicino International Airport via Milan Linate
- Ave. Duration
- 4h 10m
- When
- Monday to Saturday
- Estimated price
- €70–180
- Website
- eurowings.com
Flights from Cologne Bonn Airport to Fiumicino International Airport
- Ave. Duration
- 1h 55m
- When
- Monday, Wednesday, Friday, and Sunday
- Estimated price
- €65–200
Flights from Stuttgart Airport to Fiumicino International Airport
- Ave. Duration
- 1h 40m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €65–180
Flights from Düsseldorf International Airport to Fiumicino International Airport
- Ave. Duration
- 2h 5m
- When
- Every day
- Estimated price
- €60–170
- Website
- airdolomiti.it
Flights from Frankfurt to Florence Peretola Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- €110–360
- Website
- ryanair.com
Flights from Cologne Bonn Airport to Fiumicino International Airport
- Ave. Duration
- 2h
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €55–150
- Website
- swiss.com
Flights from Stuttgart Airport to Fiumicino International Airport via Zurich
- Ave. Duration
- 3h 40m
- When
- Monday, Tuesday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- €75–300
Flights from Frankfurt to Florence Peretola Airport via Zurich
- Ave. Duration
- 3h 57m
- When
- Every day
- Estimated price
- €120–250
- Website
- easyjet.com
Flights from Frankfurt to Fiumicino International Airport
- Ave. Duration
- 1h 50m
- When
- Every day
- Estimated price
- €35–130
- Website
- condor.com
Flights from Frankfurt to Fiumicino International Airport
- Ave. Duration
- 1h 50m
- When
- Every day
- Estimated price
- €50–210
- Website
- luxair.lu
Flights from Frankfurt to Florence Peretola Airport via Luxembourg
- Ave. Duration
- 4h 5m
- When
- Sunday
- Estimated price
- €85–420
- Phone
- +49 30 311 682904
- Website
- bahn.de
Train from Wetzlar Bahnhof to Frankfurt
- Ave. Duration
- 51 min
- Frequency
- 3 times a day
- Estimated price
- €27–30
- Website
- https://int.bahn.de/en
Train from Frankfurt to Basel SBB
- Ave. Duration
- 3h 1m
- Frequency
- Hourly
- Estimated price
- €55–65
- Website
- https://int.bahn.de/en
Train from Gießen Bahnhof to Frankfurt
- Ave. Duration
- 40 min
- Frequency
- Every 4 hours
- Estimated price
- €25–29
- Website
- https://int.bahn.de/en
Train from Frankfurt to München Hbf
- Ave. Duration
- 3h 15m
- Frequency
- Hourly
- Estimated price
- €65–75
- Website
- https://int.bahn.de/en
Train from Wetzlar Bahnhof to Siegen Hbf
- Ave. Duration
- 40 min
- Frequency
- Every 4 hours
- Estimated price
- €25–28
- Website
- https://int.bahn.de/en
Train from Frankfurt to Hauptbahnhof
- Ave. Duration
- 1h 18m
- Frequency
- Hourly
- Estimated price
- €40–45
- Website
- https://int.bahn.de/en
Train from Koeln Messe/Deutz to Duesseldorf Flughafen
- Ave. Duration
- 48 min
- Frequency
- Once daily
- Estimated price
- €23–26
- Website
- https://int.bahn.de/en
- Phone
- +41 848 446 688
- Website
- sbb.ch
Train from Frankfurt to Basel SBB
- Ave. Duration
- 2h 48m
- Frequency
- Twice a week
- Estimated price
- €110–200
- Website
- https://www.sbb.ch/en
Train from Basel SBB to Lugano
- Ave. Duration
- 2h 54m
- Frequency
- Every 3 hours
- Estimated price
- €85–160
- Website
- https://www.sbb.ch/en
Train from Lugano to Milano Centrale
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €24–45
- Website
- https://www.sbb.ch/en
- Phone
- +49 (0) 7531 915109
- info@sbb-deutschland.de
- Website
- sbb-deutschland.de
Train from Basel SBB to Lugano
- Ave. Duration
- 3h 21m
- Frequency
- Once daily
- Estimated price
- €20–25
- Schedules at
- sbb-deutschland.de
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Milano Centrale to Roma Termini
- Ave. Duration
- 3h 12m
- Frequency
- Every 30 minutes
- Estimated price
- €80–160
- Schedules at
- trenitalia.com
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Milano Centrale to Roma Termini
- Ave. Duration
- 3h 39m
- Frequency
- Hourly
- Estimated price
- €40–95
- Website
- https://www.italotreno.it/en
- Smart Economy
- €70–95
- Smart Flex
- €75–95
Train from Firenze Santa Maria Novella to Roma Termini
- Ave. Duration
- 1h 32m
- Frequency
- Hourly
- Estimated price
- €45–60
- Website
- https://www.italotreno.it/en
- Smart Economy
- €45–60
- Smart Flex
- €45–60
- Phone
- +49 30 2970
- Website
- bahn.de
Train from Gießen Bahnhof to Frankfurt
- Ave. Duration
- 45 min
- Frequency
- Hourly
- Estimated price
- €13–19
- Website
- https://int.bahn.de/en
Train from Siegen Hbf to Troisdorf Bf
- Ave. Duration
- 1h 8m
- Frequency
- Hourly
- Estimated price
- €15–21
- Website
- https://int.bahn.de/en
Train from Siegen Hbf to Köln Messe/Deutz Bf
- Ave. Duration
- 1h 24m
- Frequency
- Hourly
- Estimated price
- €17–24
- Website
- https://int.bahn.de/en
- Phone
- +43 51717
- Website
- nightjet.com
Night train from Muenchen Hbf to Roma Tiburtina
- Ave. Duration
- 13h 58m
- Frequency
- Once daily
- Estimated price
- €75–280
- Website
- https://www.nightjet.com/en/#/home
- Sleeper Carriage
- €260–280
- Couchette Carriage
- €160–190
- Seating Carriage
- €75–100
- Phone
- 0221 13 999 444
- Website
- nationalexpress.de
Train from Koeln Messe/Deutz to Duesseldorf Flughafen
- Ave. Duration
- 34 min
- Frequency
- Every 30 minutes
- Estimated price
- €10–15
- Schedules at
- nationalexpress.de
- Phone
- +49 (0) 221 800 20 820
- info@urlaubs-express.de
- Website
- urlaubs-express.de
Car train from Fulda to Villach Hbf
- Ave. Duration
- 4h 29m
- Frequency
- Once daily
- Estimated price
- €100–800
- Website
- https://urlaubs-express.de/?lang=en
- Car Single Bed
- €390–430
- Car Compartment
- €700–800
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Frankfurt central train station to Roma, Autostazione Tiburtina
- Ave. Duration
- 20h 5m
- Frequency
- Once daily
- Estimated price
- €80–140
- Website
- https://www.flixbus.co.uk
Want to know more about travelling around Italy
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Italy Travel Guides
Read the travel guide
Heading to Europe? Read this before you buy a Eurail Pass
Read the travel guide
Getting to Rome from the airport
Read the travel guide
More Questions & Answers
There are 21498+ hotels available in Rome.









































