There are 11 ways to get from Wetzlar to Rome by train, plane, bus, night train, car, or car train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train to Frankfurt, fly to Fiumicino International Airport
best- Take the train from Gießen Bahnhof to Frankfurttrain
- Fly from Frankfurt (FRA) to Fiumicino International Airport (FCO)plane FRA - FCO
6h 48m€63–206Train
- Take the train from Gießen Bahnhof to Frankfurttrain
- Take the train from Frankfurt to Basel SBBtrain 12 / ...
- Take the train from Basel SBB to Luganotrain Ec
- Take the train from Lugano to Milano Centraletrain
- Take the train from Milano Centrale to Roma Terminitrain
15h 6m€186–505Bus
- Take the bus from Gießen to Frankfurtbus
- Take the bus from Mühlheim am Main to Roma Prenestina A1bus
15h 45m€117–181Train, night train
- Take the train from Gießen Bahnhof to Frankfurttrain
- Take the train from Frankfurt to München Hbftrain 41 / ...
- Take the nighttrain from Muenchen Hbf to Roma Tiburtinanighttrain Nj
21h 43m€132–340Train, train to Düsseldorf International Airport, fly to Fiumicino International Airport
- Take the train from Wetzlar Bahnhof to Koblenz Hauptbahnhoftrain
- Take the train from Koblenz Hbf to Duesseldorf Hbftrain
- Fly from Düsseldorf International Airport (DUS) to Fiumicino International Airport (FCO)plane DUS - FCO
8h 22m€112–361Train, train to Cologne Bonn Airport, fly to Fiumicino International Airport
- Take the train from Wetzlar Bahnhof to Limburgtrain
- Take the train from Limburg to Siegburg Bftrain
- Fly from Cologne Bonn Airport (CGN) to Fiumicino International Airport (FCO)plane CGN - FCO
7h 53m€99–304Train to Frankfurt, fly to Florence Peretola Airport, train
- Take the train from Gießen Bahnhof to Frankfurttrain
- Fly from Frankfurt (FRA) to Florence Peretola Airport (FLR)plane FRA - FLR
- Take the train from Firenze S.M.N. to Roma Terminitrain
8h 3m€165–437Train, train to Stuttgart Airport, fly to Fiumicino International Airport
- Take the train from Gießen Bahnhof to Frankfurttrain
- Take the train from Frankfurt to Hauptbahnhoftrain
- Fly from Stuttgart Airport (STR) to Fiumicino International Airport (FCO)plane STR - FCO
8h 41m€119–311Drive, car train
- Drive from Wetzlar to Fuldacar
- Take the cartrain from Fulda to Villach Hbfcartrain
- Drive from Villach Hbf to Romecar
17h 46m€229–321Train, bus
- Take the train from Gießen Bahnhof to Frankfurttrain Re30
- Take the bus from Frankfurt central train station to Roma, Autostazione Tiburtinabus N77
23h 55m€122–230Drive 1,288.7 km
- Drive from Wetzlar to Romecar 1,288.7 km
12h 2m€209–301
Wetzlar to Rome by bus, train, and night train
Comparing Your Travel Options
The cheapest way to get from Wetzlar to Rome is to train and fly which costs €60 - €210 and takes 6h 48m.
The fastest way to get from Wetzlar to Rome is to train and fly which takes 6h 48m and costs €60 - €210.
No, there is no direct bus from Wetzlar to Rome. However, there are services departing from Wetzlar Bahnhof/ZOB and arriving at Roma Prenestina A1 via Gießen Berliner Platz, Gießen and Mühlheim am Main. The journey, including transfers, takes approximately 15h 45m.
No, there is no direct train from Wetzlar to Rome. However, there are services departing from Wetzlar Bahnhof and arriving at Roma Termini via Gießen Bahnhof, Frankfurt, Basel SBB, Lugano and Milano Centrale. The journey, including transfers, takes approximately 15h 6m.
The distance between Wetzlar and Rome is 1082 km. The road distance is 1288.7 km.
The best way to get from Wetzlar to Rome without a car is to train which takes 15h 6m and costs €180 - €550.
It takes approximately 6h 48m to get from Wetzlar to Rome, including transfers.
Wetzlar to Rome bus services, operated by Ecolines, depart from Gießen station.
Wetzlar to Rome train services, operated by Deutsche Bahn Regio (DB Regional), depart from Gießen Bahnhof station.
The best way to get from Wetzlar to Rome is to train which takes 15h 6m and costs €180 - €550. Alternatively, you can bus, which costs €110 - €190 and takes 15h 45m.
What companies run services between Wetzlar, Germany and Rome, Italy?
You can take a train from Wetzlar Bahnhof to Roma Termini via Gießen Bahnhof, Frankfurt, Basel SBB, Lugano, and Milano Centrale in around 15h 6m. Alternatively, you can take a bus from Wetzlar Bahnhof/ZOB to Roma Prenestina A1 via Gießen Stadttheater, Gießen Berliner Platz, Gießen An der Automeile, Gießen, Frankfurt, Frankfurt, Mühlheim, and Mühlheim am Main in around 15h 45m.
- Website
- lufthansa.com
Flights from Frankfurt to Fiumicino International Airport
- Ave. Duration
- 1h 53m
- When
- Every day
- Estimated price
- €70–130
Flights from Frankfurt to Fiumicino International Airport via Munich
- Ave. Duration
- 3h 50m
- When
- Every day
- Estimated price
- €70–130
Flights from Düsseldorf International Airport to Fiumicino International Airport via Munich
- Ave. Duration
- 3h 46m
- When
- Every day
- Estimated price
- €55–300
Flights from Düsseldorf International Airport to Fiumicino International Airport via Frankfurt
- Ave. Duration
- 4h 5m
- When
- Every day
- Estimated price
- €80–300
Flights from Cologne Bonn Airport to Fiumicino International Airport via Munich
- Ave. Duration
- 4h 22m
- When
- Monday, Friday, Sunday, Thursday, and Saturday
- Estimated price
- €95–240
Flights from Frankfurt to Florence Peretola Airport
- Ave. Duration
- 1h 36m
- When
- Every day
- Estimated price
- €100–550
Flights from Frankfurt to Florence Peretola Airport via Munich
- Ave. Duration
- 3h 6m
- When
- Every day
- Estimated price
- €170–550
Flights from Stuttgart Airport to Fiumicino International Airport via Munich
- Ave. Duration
- 3h 50m
- When
- Monday to Saturday
- Estimated price
- €80–300
- Website
- ita-airways.com
Flights from Frankfurt to Fiumicino International Airport
- Ave. Duration
- 1h 53m
- When
- Every day
- Estimated price
- €70–130
Flights from Frankfurt to Fiumicino International Airport via Milan Linate
- Ave. Duration
- 3h 17m
- When
- Every day
- Estimated price
- €75–420
Flights from Düsseldorf International Airport to Fiumicino International Airport via Milan Linate
- Ave. Duration
- 3h 45m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €65–190
Flights from Düsseldorf International Airport to Fiumicino International Airport via Munich
- Ave. Duration
- 4h 5m
- When
- Monday to Thursday
- Estimated price
- €85–300
Flights from Cologne Bonn Airport to Fiumicino International Airport
- Ave. Duration
- 2h
- When
- Every day
- Estimated price
- €80–200
Flights from Cologne Bonn Airport to Fiumicino International Airport via Bologna
- Ave. Duration
- 4h 5m
- When
- Monday, Friday, and Sunday
- Estimated price
- €80–200
Flights from Frankfurt to Florence Peretola Airport
- Ave. Duration
- 1h 36m
- When
- Every day
- Estimated price
- €100–550
Flights from Stuttgart Airport to Fiumicino International Airport
- Ave. Duration
- 1h 37m
- When
- Every day
- Estimated price
- €70–150
- Website
- eurowings.com
Flights from Düsseldorf International Airport to Fiumicino International Airport
- Ave. Duration
- 2h 5m
- When
- Every day
- Estimated price
- €65–190
Flights from Cologne Bonn Airport to Fiumicino International Airport
- Ave. Duration
- 2h
- When
- Every day
- Estimated price
- €80–200
Flights from Stuttgart Airport to Fiumicino International Airport
- Ave. Duration
- 1h 37m
- When
- Every day
- Estimated price
- €70–150
- Website
- airdolomiti.it
Flights from Frankfurt to Florence Peretola Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- €160–550
- Website
- condor.com
Flights from Frankfurt to Fiumicino International Airport
- Ave. Duration
- 1h 50m
- When
- Monday to Friday
- Estimated price
- €70–160
Flights from Frankfurt to Florence Peretola Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- €130–320
- Website
- ryanair.com
Flights from Cologne Bonn Airport to Fiumicino International Airport
- Ave. Duration
- 2h
- When
- Every day
- Estimated price
- €65–210
- Website
- swiss.com
Flights from Frankfurt to Florence Peretola Airport via Zurich
- Ave. Duration
- 3h 10m
- When
- Every day
- Estimated price
- €85–350
Flights from Stuttgart Airport to Fiumicino International Airport via Zurich
- Ave. Duration
- 3h 15m
- When
- Every day
- Estimated price
- €70–290
- Website
- easyjet.com
Flights from Frankfurt to Fiumicino International Airport
- Ave. Duration
- 1h 50m
- When
- Every day
- Estimated price
- €45–120
- Website
- lufthansa-city.com
Flights from Düsseldorf International Airport to Fiumicino International Airport via Munich
- Ave. Duration
- 3h 30m
- When
- Friday
- Estimated price
- €55–300
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Gießen Bahnhof to Frankfurt
- Ave. Duration
- 58 min
- Frequency
- Every 2 hours
- Estimated price
- €12–50
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Gießen Bahnhof to Frankfurt
- Ave. Duration
- 58 min
- Frequency
- Every 2 hours
- Estimated price
- €12–50
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Gießen Bahnhof to Frankfurt
- Ave. Duration
- 58 min
- Frequency
- Every 2 hours
- Estimated price
- €12–50
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Wetzlar Bahnhof to Koblenz Hauptbahnhof
- Ave. Duration
- 1h 34m
- Frequency
- Every 4 hours
- Estimated price
- €19–80
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Wetzlar Bahnhof to Limburg
- Ave. Duration
- 42 min
- Frequency
- Every 4 hours
- Estimated price
- €9–40
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Gießen Bahnhof to Frankfurt
- Ave. Duration
- 58 min
- Frequency
- Every 2 hours
- Estimated price
- €12–50
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Gießen Bahnhof to Frankfurt
- Ave. Duration
- 58 min
- Frequency
- Every 2 hours
- Estimated price
- €12–50
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Gießen Bahnhof to Frankfurt
- Ave. Duration
- 58 min
- Frequency
- Every 2 hours
- Estimated price
- €12–50
- Website
- Deutsche Bahn Regio (DB Regional)
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Gießen Bahnhof to Frankfurt
- Ave. Duration
- 44 min
- Frequency
- Once daily
- Estimated price
- €11–25
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Gießen Bahnhof to Frankfurt
- Ave. Duration
- 44 min
- Frequency
- Once daily
- Estimated price
- €11–25
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Frankfurt to Basel SBB
- Ave. Duration
- 2h 58m
- Frequency
- Hourly
- Estimated price
- €55–130
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Gießen Bahnhof to Frankfurt
- Ave. Duration
- 44 min
- Frequency
- Once daily
- Estimated price
- €11–25
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Frankfurt to München Hbf
- Ave. Duration
- 3h 15m
- Frequency
- Hourly
- Estimated price
- €65–150
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Koblenz Hbf to Duesseldorf Hbf
- Ave. Duration
- 1h 20m
- Frequency
- Hourly
- Estimated price
- €22–50
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Limburg to Siegburg Bf
- Ave. Duration
- 31 min
- Frequency
- Every 2 hours
- Estimated price
- €14–35
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Gießen Bahnhof to Frankfurt
- Ave. Duration
- 44 min
- Frequency
- Once daily
- Estimated price
- €11–25
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Gießen Bahnhof to Frankfurt
- Ave. Duration
- 44 min
- Frequency
- Once daily
- Estimated price
- €11–25
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Frankfurt to Hauptbahnhof
- Ave. Duration
- 1h 18m
- Frequency
- Hourly
- Estimated price
- €30–70
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Gießen Bahnhof to Frankfurt
- Ave. Duration
- 44 min
- Frequency
- Once daily
- Estimated price
- €11–25
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Basel SBB to Lugano
- Ave. Duration
- 2h 54m
- Frequency
- Every 3 hours
- Estimated price
- €90–150
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Lugano to Milano Centrale
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €28–45
- Website
- Swiss Federal Railways (SBB CFF FFS)
- Phone
- +49 (0) 7531 915109
- info@sbb-deutschland.de
- Website
- SBB GmbH
Train from Basel SBB to Lugano
- Ave. Duration
- 3h 21m
- Frequency
- Once daily
- Estimated price
- €20–25
- Schedules at
- SBB GmbH
- Phone
- +39 06 8937 1892
- Website
- Italo Treno
Train from Milano Centrale to Roma Termini
- Ave. Duration
- 3h 5m
- Frequency
- Every 30 minutes
- Estimated price
- €70–120
- Website
- Italo Treno
- Phone
- +43 (0) 51717
- Website
- Nightjet
Night train from Muenchen Hbf to Roma Tiburtina
- Ave. Duration
- 14h 6m
- Frequency
- Twice daily
- Estimated price
- €55–140
- Website
- Nightjet
- Sleeper Carriage
- €110–140
- Couchette Carriage
- €85–100
- Seating Carriage
- €55–65
- Phone
- +49 221 13 999 444
- Website
- National Express
Train from Koblenz Hbf to Duesseldorf Hbf
- Ave. Duration
- 1h 43m
- Frequency
- Hourly
- Schedules at
- National Express
- Phone
- +31 30 751 5155
- Website
- Nederlandse Spoorwegen (NS)
Train from Koblenz Hbf to Duesseldorf Hbf
- Ave. Duration
- 1h 31m
- Frequency
- Once daily
- Estimated price
- €14–28
- Website
- Nederlandse Spoorwegen (NS)
- Phone
- +32 70 79 79 79
- Website
- Belgian Railways
Train from Limburg to Siegburg Bf
- Ave. Duration
- 31 min
- Frequency
- 3 times a week
- Estimated price
- €15–23
- Website
- Belgian Railways
- Phone
- +39 06 5210550
- Website
- Trenitalia Frecce
Train from Firenze S.M.N. to Roma Termini
- Ave. Duration
- 1h 36m
- Frequency
- Every 20 minutes
- Estimated price
- €35–65
- Website
- Trenitalia Frecce
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Firenze S.M.N. to Roma Termini
- Ave. Duration
- 3h 51m
- Frequency
- Every 4 hours
- Estimated price
- €30–45
- Website
- Trenitalia
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Firenze S.M.N. to Roma Termini
- Ave. Duration
- 2h 40m
- Frequency
- Twice daily
- Estimated price
- €28–55
- Website
- Trenitalia Intercity
- Phone
- +49 (0) 221 800 20 820
- info@urlaubs-express.de
- Website
- Urlaubs-Express (UEX)
Car train from Fulda to Villach Hbf
- Ave. Duration
- 9h 1m
- Frequency
- Once a week
- Estimated price
- €95–120
- Website
- Urlaubs-Express (UEX)
- Phone
- +371 67 214 512
- info@ecolines.lv
- Website
- ecolines.net
Bus from Gießen to Frankfurt
- Ave. Duration
- 50 min
- Frequency
- 6 times a week
- Estimated price
- €4–8
- Schedules at
- ecolines.net
- Phone
- +39 0362 185 0590
- info@onebus.it
- Website
- Onebus
Bus from Mühlheim am Main to Roma Prenestina A1
- Ave. Duration
- 10h 55m
- Frequency
- Once a week
- Estimated price
- €110–160
- Website
- Onebus
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- Flixbus
Bus from Frankfurt central train station to Roma, Autostazione Tiburtina
- Ave. Duration
- 20h 5m
- Frequency
- Once daily
- Estimated price
- €110–180
- Website
- Flixbus
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Booking & Getting There
Wetzlar to Rome bus services, operated by Ecolines, arrive at Frankfurt station.
Wetzlar to Rome train services, operated by Deutsche Bahn Regio (DB Regional), arrive at Frankfurt station.
Yes, the driving distance between Wetzlar to Rome is 1289 km. It takes approximately 12h 2m to drive from Wetzlar to Rome.
Book your Wetzlar to Rome train tickets online with Omio.
Book your Wetzlar to Rome bus tickets online with Omio.
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