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How to get fromWesley Chapel to Key Westby bus, plane, ferry, train, car or shuttle

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There are 7 ways to get from Wesley Chapel to Key West by bus, plane, ferry, train, car, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Tampa, fly

    best
    1. Take the bus from SR 54 & Saddlebrook Way to Wiregrass Park and Ridebus bus
    2. Fly from Tampa (TPA) to Key West International Airport (EYW)plane plane TPA - EYW
    5h 6m
    $130–386

  2. Drive 398.4 mi

    cheapest
    1. Drive from Wesley Chapel to Key Westcar car 398.4 mi
    8h 12m
    $73–105

  3. Bus, ferry via Marco Island

    1. Take the bus from University of South Florida Tampa to Naples, FLbus bus Tampa / ...
    2. Take the ferry from Marco Island, FL to Key West, FLferry ferry Key West
    11h 33m
    $188–316

  4. Train, bus

    1. Take the train from Tampa to Delray Beach Amtraktrain train
    2. Take the train from Delray Beach Station to Miami Airport Stationtrain train
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    4. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus bus Lks
    13h 26m
    $119–226

  5. Drive to Orlando Sanford, fly

    1. Drive from Wesley Chapel to Orlando-Sanford-Airport-SFBcar car
    2. Fly from Orlando Sanford (SFB) to Key West International Airport (EYW)plane plane SFB - EYW
    3h 36m
    $84–439

  6. Bus, shuttle, line 300 bus to Saint Petersburg–Clearwater International Airport, fly

    1. Take the bus from SR 54 & Saddlebrook Way to Wiregrass Park and Ridebus bus
    2. Take a shuttle bus from Gate Gas Station Wesley Chapel to Tampa International Airport - Red Terminalshuttle bus
    3. Take the bus from TPA RENTAL CAR FACILITY westbound to Psta 34Th St Layby - Platform - Dbus bus
    4. Fly from Saint Petersburg–Clearwater International Airport (PIE) to Key West International Airport (EYW)plane plane PIE - EYW
    7h 14m
    $102–452

  7. Bus, ferry

    1. Take the bus from Tampa Bus Station to Fort Myers Bus Stopbus bus FlixBus 2421
    2. Take the ferry from Fort Myers Beach, FL to Key West, FLferry ferry Fort Myers Beach
    13h 5m
    $186–206

Tampa (TPA) to Key West International Airport (EYW) flights

Calendar12Weekly Planes
Duration2h 22mAverage Duration
Ticket$56Cheapest Price
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Questions & Answers

What companies run services between Wesley Chapel, FL, USA and Key West, FL, USA?

There is no direct connection from Wesley Chapel to Key West. However, you can take the bus to Wiregrass Park and Ride, take the bus to SR 56 & Cypress Ridge Blvd, walk to Gate Gas Station Wesley Chapel, take the shuttle to Tampa International Airport - Red Terminal, walk to Tampa (TPA) airport, fly to Key West International Airport (EYW), then take the taxi to Key West. Alternatively, you can take a bus from SR 54 & Saddlebrook Way to Key West, FL via Wiregrass Park n Ride, University Area Transit Center, UATC to Mall/ Library, University of South Florida Tampa, Naples, FL, and Marco Island, FL in around 11h 33m.

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