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How to get fromWeslaco to Des Moinesby plane, bus (Greyhound), car, bus or bus (Flixbus)

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There are 6 ways to get from Weslaco to Des Moines by plane, bus (Greyhound), car, bus, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Mcallen Miller International Airport

    best
    1. Fly from Mcallen Miller International Airport (MFE) to Des Moines (DSM)planeMFE - DSM
    6h 20m
    $224–1,030

  2. Bus via Dallas

    cheapest
    1. Take the bus from McAllen Central Station to Dallasbus
    2. Take the bus from Dallas Bus Station to Kansas City Bus Stationbus
    3. Take the bus from Kansas City to Des Moinesbus
    27h 11m
    $173–355

  3. Drive 1,185.1 mi

    1. Drive from Weslaco to Des Moinescar1,185.1 mi
    20h 19m
    $217–313

  4. Fly from Rio Grande Valley International Airport

    1. Fly from Rio Grande Valley International Airport (HRL) to Des Moines (DSM)planeHRL - DSM
    7h 33m
    $191–875

  5. Bus to Brownsville-South Padre Island International Airport, fly

    1. Take the bus from STC Mid Valley Campus to La Plaza at Brownsvillebus
    2. Fly from Brownsville-South Padre Island International Airport (BRO) to Des Moines (DSM)planeBRO - DSM
    8h
    $221–1,025

  6. Bus

    1. Take the bus from McAllen Central Station to San Marcosbus
    2. Take the bus from San Marcos to Omahabus
    3. Take the bus from Omaha to Des Moinesbus
    32h 25m

Mcallen Miller International Airport (MFE) to Des Moines (DSM) flights

Calendar44Weekly Planes
Duration6h 26mAverage Duration
Ticket$202Cheapest Price
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Questions & Answers

What companies run services between Weslaco, TX, USA and Des Moines, IA, USA?

American Airlines, United Airlines, and Allegiant Air fly from Mcallen Miller International Airport (MFE) to Des Moines (DSM) every 4 hours. Alternatively, you can take a bus from STC Mid Valley Campus to Des Moines via McAllen Central Station, Dallas, Jefferson @ Marsalis - E - Ns, Commerce @ Austin - E - Ns, Dallas Bus Station, and Kansas City in around 27h 11m.

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