There are 6 ways to get from Wellesley to Buffalo by train, plane, bus (Greyhound), train (Amtrak), car, bus, or bus (Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train, fly to Buffalo Niagara International Airport
best- Take the train from Wellesley Square to Back Baytrain
- Fly from Boston Logan Airport (BOS) to Buffalo Niagara International Airport (BUF)plane BOS - BUF
5h 2m$97–545Bus (Greyhound)
cheapest- Take the bus from Boston to Buffalobus Greyhound US0171
13h 9m$69–143Train (Amtrak)
- Take the train from Framingham Amtrak to Buffalo Depew Stationtrain Lake Shore Limited
13h 39m$123–427Drive 441.2 mi
- Drive from Wellesley to Buffalocar 441.2 mi
7h 44m$81–117Fly to Rochester, bus
- Fly from Boston Logan Airport (BOS) to Rochester (ROC)plane BOS - ROC
- Take the bus from Rochester Bus Stop to Buffalobus
6h 26m$135–659Bus via Ithaca
- Take the bus from Boston to Ithacabus FlixBus 2691
- Take the bus from Ithaca to Buffalobus Adt N806
14h 15m$76–133
Wellesley to Buffalo by train and bus (Greyhound)
Questions & Answers
The cheapest way to get from Wellesley to Buffalo is to bus which costs $65 - $150 and takes 13h 9m.
The fastest way to get from Wellesley to Buffalo is to train and fly which takes 5h 2m and costs $95 - $550.
No, there is no direct bus from Wellesley to Buffalo. However, there are services departing from Framingham and arriving at Buffalo via Boston. The journey, including transfers, takes approximately 13h 9m.
No, there is no direct train from Wellesley to Buffalo. However, there are services departing from Wellesley Square and arriving at Buffalo via Framingham Amtrak and Buffalo Depew Station. The journey, including transfers, takes approximately 13h 39m.
The distance between Wellesley and Buffalo is 425 miles. The road distance is 443.8 miles.
The best way to get from Wellesley to Buffalo without a car is to bus which takes 13h 9m and costs $65 - $150.
It takes approximately 5h 2m to get from Wellesley to Buffalo, including transfers.
Wellesley to Buffalo bus services, operated by Greyhound USA, depart from Boston station.
Wellesley to Buffalo train services, operated by Amtrak, depart from Framingham Amtrak station.
The best way to get from Wellesley to Buffalo is to bus which takes 13h 9m and costs $65 - $150. Alternatively, you can train, which costs $120 - $430 and takes 13h 39m.
What companies run services between Wellesley, MA, USA and Buffalo, NY, USA?
Greyhound USA operates a bus from Boston to Buffalo once daily. Tickets cost $65–130 and the journey takes 10h 5m. Alternatively, Amtrak operates a train from Framingham Amtrak to Buffalo Depew Station once daily. Tickets cost $120–280 and the journey takes 11h 4m.
- Website
- aa.com
Flights from Boston Logan Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 43m
- When
- Every day
- Estimated price
- $80–500
Flights from Boston Logan Airport to Rochester
- Ave. Duration
- 1h 32m
- When
- Every day
- Estimated price
- $95–600
- Website
- southwest.com
Flights from Boston Logan Airport to Buffalo Niagara International Airport via Baltimore
- Ave. Duration
- 3h 45m
- When
- Tuesday, Wednesday, and Saturday
- Estimated price
- $100–600
Flights from Boston Logan Airport to Rochester via Baltimore
- Ave. Duration
- 3h 45m
- When
- Saturday, Monday, Thursday, and Friday
- Estimated price
- $130–750
- Website
- jetblue.com
Flights from Boston Logan Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 42m
- When
- Every day
- Estimated price
- $80–500
- Website
- united.com
Flights from Boston Logan Airport to Buffalo Niagara International Airport via Newark
- Ave. Duration
- 3h 52m
- When
- Every day
- Estimated price
- $85–550
- Website
- delta.com
Flights from Boston Logan Airport to Rochester via New York La Guardia
- Ave. Duration
- 3h 48m
- When
- Monday to Friday
- Estimated price
- $100–650
Train from Wellesley Square to Back Bay
- Ave. Duration
- 35 min
- Frequency
- Hourly
- Estimated price
- $2–8
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $2–8
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Framingham Amtrak to Buffalo Depew Station
- Ave. Duration
- 11h 4m
- Frequency
- Once daily
- Estimated price
- $120–280
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- Greyhound
Bus from Boston to Buffalo
- Ave. Duration
- 10h 5m
- Frequency
- Once daily
- Estimated price
- $65–130
- Website
- Greyhound
Bus from Rochester Bus Stop to Buffalo
- Ave. Duration
- 1h 20m
- Frequency
- 5 times a day
- Estimated price
- $10–20
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Rochester Bus Stop to Buffalo
- Ave. Duration
- 1h 30m
- Frequency
- 5 times a day
- Estimated price
- $10–17
- Schedules at
- Flixbus USA
Bus from Boston to Ithaca
- Ave. Duration
- 7h 44m
- Frequency
- 3 times a week
- Estimated price
- $50–85
- Schedules at
- Flixbus USA
Bus from Ithaca to Buffalo
- Ave. Duration
- 3h 45m
- Frequency
- Once daily
- Estimated price
- $23–40
- Schedules at
- Flixbus USA
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More Questions & Answers
Wellesley to Buffalo bus services, operated by Greyhound USA, arrive at Buffalo station.
Wellesley to Buffalo train services, operated by Amtrak, arrive at Buffalo Depew Station.
Yes, the driving distance between Wellesley to Buffalo is 444 miles. It takes approximately 7h 44m to drive from Wellesley to Buffalo.
There are 264+ hotels available in Buffalo.













