There are 6 ways to get from Wellesley to Buffalo by train, plane, bus (Greyhound), train (Amtrak), car, bus, or bus (Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train, fly to Buffalo Niagara International Airport
best- Take the train from Wellesley Square to Back Baytrain
- Fly from Boston Logan Airport (BOS) to Buffalo Niagara International Airport (BUF)plane BOS - BUF
4h 46m$94–596Bus (Greyhound)
cheapest- Take the bus from Boston to Buffalobus Greyhound US0171
13h 8m$74–154Train (Amtrak)
- Take the train from Framingham Amtrak to Buffalo Depew Stationtrain Lake Shore Limited
13h 38m$143–457Drive 441.2 mi
- Drive from Wellesley to Buffalocar 441.2 mi
7h 44m$81–117Fly to Rochester, bus
- Fly from Boston Logan Airport (BOS) to Rochester (ROC)plane BOS - ROC
- Take the bus from Rochester Bus Stop to Buffalobus
6h 27m$126–660Bus via Ithaca
- Take the bus from Boston to Ithacabus FlixBus 2691
- Take the bus from Ithaca to Buffalobus Adt N806
14h 15m$84–153
Wellesley to Buffalo by train and bus (Greyhound)
Questions & Answers
The cheapest way to get from Wellesley to Buffalo is to bus which costs $70 - $160 and takes 13h 8m.
The fastest way to get from Wellesley to Buffalo is to train and fly which takes 4h 46m and costs $90 - $600.
No, there is no direct bus from Wellesley to Buffalo. However, there are services departing from Framingham and arriving at Buffalo via Boston. The journey, including transfers, takes approximately 13h 8m.
No, there is no direct train from Wellesley to Buffalo. However, there are services departing from Wellesley Square and arriving at Buffalo via Framingham Amtrak and Buffalo Depew Station. The journey, including transfers, takes approximately 13h 38m.
The distance between Wellesley and Buffalo is 429 miles. The road distance is 443.8 miles.
The best way to get from Wellesley to Buffalo without a car is to bus which takes 13h 8m and costs $70 - $160.
It takes approximately 4h 46m to get from Wellesley to Buffalo, including transfers.
Wellesley to Buffalo bus services, operated by Greyhound USA, depart from Boston station.
Wellesley to Buffalo train services, operated by Amtrak, depart from Framingham Amtrak station.
The best way to get from Wellesley to Buffalo is to bus which takes 13h 8m and costs $70 - $160. Alternatively, you can train, which costs $140 - $460 and takes 13h 38m.
What companies run services between Wellesley, MA, USA and Buffalo, NY, USA?
Greyhound USA operates a bus from Boston to Buffalo once daily. Tickets cost $70–140 and the journey takes 10h 5m. Alternatively, Amtrak operates a train from Framingham Amtrak to Buffalo Depew Station once daily. Tickets cost $140–310 and the journey takes 11h 4m.
- Website
- aa.com
Flights from Boston Logan Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 46m
- When
- Every day
- Estimated price
- $80–550
Flights from Boston Logan Airport to Buffalo Niagara International Airport via Philadelphia
- Ave. Duration
- 3h 58m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $100–600
Flights from Boston Logan Airport to Buffalo Niagara International Airport via New York La Guardia
- Ave. Duration
- 4h 3m
- When
- Saturday
- Estimated price
- $90–550
Flights from Boston Logan Airport to Rochester
- Ave. Duration
- 1h 33m
- When
- Every day
- Estimated price
- $85–600
- Website
- southwest.com
Flights from Boston Logan Airport to Buffalo Niagara International Airport via Baltimore
- Ave. Duration
- 3h 48m
- When
- Tuesday, Wednesday, Saturday, and Sunday
- Estimated price
- $110–600
Flights from Boston Logan Airport to Rochester via Baltimore
- Ave. Duration
- 3h 51m
- When
- Every day
- Estimated price
- $120–700
- Website
- jetblue.com
Flights from Boston Logan Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 34m
- When
- Every day
- Estimated price
- $80–550
- Website
- united.com
Flights from Boston Logan Airport to Buffalo Niagara International Airport via Newark
- Ave. Duration
- 3h 55m
- When
- Every day
- Estimated price
- $90–550
Flights from Boston Logan Airport to Buffalo Niagara International Airport via Washington Dulles
- Ave. Duration
- 4h 3m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $110–650
Flights from Boston Logan Airport to Rochester via Washington Dulles
- Ave. Duration
- 3h 53m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $130–700
- Website
- delta.com
Flights from Boston Logan Airport to Buffalo Niagara International Airport via New York La Guardia
- Ave. Duration
- 3h 47m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $90–550
Flights from Boston Logan Airport to Rochester via New York La Guardia
- Ave. Duration
- 3h 47m
- When
- Monday to Friday
- Estimated price
- $100–600
Train from Wellesley Square to Back Bay
- Ave. Duration
- 35 min
- Frequency
- Hourly
- Estimated price
- $2–8
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $2–8
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Framingham Amtrak to Buffalo Depew Station
- Ave. Duration
- 11h 4m
- Frequency
- Once daily
- Estimated price
- $140–310
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- Greyhound
Bus from Boston to Buffalo
- Ave. Duration
- 10h 5m
- Frequency
- Once daily
- Estimated price
- $70–140
- Website
- Greyhound
Bus from Rochester Bus Stop to Buffalo
- Ave. Duration
- 1h 20m
- Frequency
- 5 times a day
- Estimated price
- $11–21
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Rochester Bus Stop to Buffalo
- Ave. Duration
- 1h 30m
- Frequency
- Every 4 hours
- Estimated price
- $11–19
- Schedules at
- Flixbus USA
Bus from Boston to Ithaca
- Ave. Duration
- 7h 44m
- Frequency
- 3 times a week
- Estimated price
- $55–100
- Schedules at
- Flixbus USA
Bus from Ithaca to Buffalo
- Ave. Duration
- 3h 45m
- Frequency
- Twice daily
- Estimated price
- $26–45
- Schedules at
- Flixbus USA
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More Questions & Answers
Wellesley to Buffalo bus services, operated by Greyhound USA, arrive at Buffalo station.
Wellesley to Buffalo train services, operated by Amtrak, arrive at Buffalo Depew Station.
Yes, the driving distance between Wellesley to Buffalo is 444 miles. It takes approximately 7h 44m to drive from Wellesley to Buffalo.
There are 246+ hotels available in Buffalo.













