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How to get fromWayne State University to Chicagoby train (Amtrak), bus (Greyhound, Flixbus), car, plane, bus (Flixbus), bus or train

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There are 9 ways to get from Wayne State University to Chicago by train (Amtrak), bus (Greyhound, Flixbus), car, plane, bus (Flixbus), bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Amtrak)

    best
    1. Take the train from Detroit to Chicago Union StationtrainWolverine
    5h 21m
    $40–130

  2. Bus

    cheapest
    1. Take the bus from Detroit Bus Station to Chicago Bus StationbusGreyhound US0160
    7h 29m
    $32–76

  3. Drive 279.5 mi

    1. Drive from Wayne State University to Chicagocar279.5 mi
    4h 34m
    $51–74

  4. Drive to Capital Region International Airport, fly to Chicago O'Hare International Airport

    1. Drive from Wayne State University to Capital Region International Airport (LAN)car
    2. Fly from Capital Region International Airport (LAN) to Chicago O'Hare International Airport (ORD)planeLAN - ORD
    3h 43m
    $59–349

  5. Bus via Chicago (Flixbus)

    1. Take the bus from Detroit Bus Station to ChicagobusFlixBus 2552
    9h 6m
    $44–102

  6. Line 16 bus to Detroit, fly to Chicago Midway International Airport

    1. Take the bus from Cass & Kirby to Grand River & Times Sqbus
    2. Fly from Detroit (DTW) to Chicago Midway International Airport (MDW)planeDTW - MDW
    4h 29m
    $50–338

  7. Line 16 bus to Detroit, fly to Chicago O'Hare International Airport

    1. Take the bus from Cass & Kirby to Grand River & Times Sqbus
    2. Fly from Detroit (DTW) to Chicago O'Hare International Airport (ORD)planeDTW - ORD
    4h 51m
    $116–358

  8. Bus to Bishop International Airport, fly to Chicago O'Hare International Airport

    1. Take the bus from Detroit Bus Station to Flintbus
    2. Fly from Bishop International Airport (FNT) to Chicago O'Hare International Airport (ORD)planeFNT - ORD
    6h 3m
    $76–308

  9. Fly Detroit to South Bend, train

    1. Fly from Detroit (DTW) to South Bend (SBN)planeDTW - SBN
    2. Take the train from South Bend Airport to Van Buren St.train
    6h 43m
    $62–368

Wayne State University to Chicago by foot and train (Amtrak)

Calendar21Weekly Services
Duration5h 21mAverage Duration
Ticket$40Cheapest Price
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Questions & Answers

What companies run services between Wayne State University, MI, USA and Chicago, IL, USA?

Amtrak operates a train from Detroit to Chicago Union Station 3 times a day. Tickets cost $40–130 and the journey takes 5h 6m. Alternatively, Greyhound USA operates a bus from Detroit Bus Station to Chicago Bus Station 3 times a day. Tickets cost $30–60 and the journey takes 6h 5m. Flixbus USA also services this route twice daily.

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