There are 12 ways to get from Waterville to Poughkeepsie by bus, train, car, plane, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus, train
best- Take the bus from Colby College Museum of Art to Boston, MA - South Station
- Take the train from Boston to Ny Moynihan Train Hall At Penn Station
- Take the train from Ny Moynihan Train Hall At Penn Station to Poughkeepsie Amtrak Station
10h 56m$108–889Drive 350.8 mi
cheapest- Drive from Waterville to Poughkeepsie350.8 mi
6h 43m$64–93Bus, train via New York
- Take the bus from Colby College Museum of Art to Boston, MA - South Station
- Take the bus from Boston to New York Midtown
- Take the train from Grand Central Terminal to Poughkeepsie
11h 48m$99–179Bus to Bangor, fly to Laguardia Airport, train
- Take the bus from Waterville to Bangor Park & Ride
- Fly from Bangor (BGR) to Laguardia Airport (LGA)BGR - LGA
- Take the train from 125th Street - Harlem to Poughkeepsie
7h 28m$97–408Bus, train #2
- Take the bus from Colby College Museum of Art to Boston, MA - South Station
- Take the train from Boston to Pittsfield Amtrak Station
- Take the train from Pittsfield Amtrak Station to Poughkeepsie Amtrak Station
12h 3m$82–224Bus, train via Portland
- Take the bus from Augusta Transportation Center to Portland Transportation Center
- Take the train from Portland to Boston
- Take the train from Boston to Ny Moynihan Train Hall At Penn Station
- Take the train from Ny Moynihan Train Hall At Penn Station to Poughkeepsie Amtrak Station
12h 22m$175–989Bus
- Take the bus from Colby College Museum of Art to Boston, MA - South Station
- Take the bus from Boston to White Plains Bus Station
- Take the bus from TransCenter to Metro North StationWpp
12h 22m$89–143Bus to Portland, fly to Laguardia Airport, train
- Take the bus from Waterville to City of Portland
- Fly from Portland (PWM) to Laguardia Airport (LGA)PWM - LGA
- Take the train from 125th Street - Harlem to Poughkeepsie
8h 26m$107–438Bus to Portland, fly to John F. Kennedy International Airport, train
- Take the bus from Waterville to City of Portland
- Fly from Portland (PWM) to John F. Kennedy International Airport (JFK)PWM - JFK
- Take the train from Ny Moynihan Train Hall At Penn Station to Poughkeepsie Amtrak Station
8h 36m$136–529Bus to Portland, fly to Newark Liberty International Airport, train
- Take the bus from Waterville to City of Portland
- Fly from Portland (PWM) to Newark Liberty International Airport (EWR)PWM - EWR
- Take the train from Ny Moynihan Train Hall At Penn Station to Poughkeepsie Amtrak Station
8h 56m$478–828Bus to Bangor, fly to Newark Liberty International Airport, train
- Take the bus from Waterville to Bangor Park & Ride
- Fly from Bangor (BGR) to Newark Liberty International Airport (EWR)BGR - EWR
- Take the train from Ny Moynihan Train Hall At Penn Station to Poughkeepsie Amtrak Station
8h 9m$128–458Bus to Bangor, fly to John F. Kennedy International Airport, train
- Take the bus from Waterville to Bangor Park & Ride
- Fly from Bangor (BGR) to John F. Kennedy International Airport (JFK)BGR - JFK
- Take the train from Ny Moynihan Train Hall At Penn Station to Poughkeepsie Amtrak Station
7h 57m$126–489
Bangor (BGR) to Laguardia Airport (LGA) flights
Questions & Answers
The cheapest way to get from Waterville to Poughkeepsie is to drive which costs $60 - $95 and takes 6h 43m.
The fastest way to get from Waterville to Poughkeepsie is to drive which takes 6h 43m and costs $60 - $95.
The distance between Waterville and Poughkeepsie is 492 miles. The road distance is 352.9 miles.
The best way to get from Waterville to Poughkeepsie without a car is to bus and train which takes 10h 56m and costs $100 - $900.
It takes approximately 10h 56m to get from Waterville to Poughkeepsie, including transfers.
Yes, the driving distance between Waterville to Poughkeepsie is 353 miles. It takes approximately 6h 43m to drive from Waterville to Poughkeepsie.
There are 120+ hotels available in Poughkeepsie.
What companies run services between Waterville, ME, USA and Poughkeepsie, NY, USA?
You can take a vehicle from Waterville to Metro North Station via Colby College Museum of Art, Boston, MA - South Station, Boston, White Plains Bus Station, and TransCenter in around 12h 22m.
- Website
- delta.com
Flights from Bangor to Laguardia Airport
- Ave. Duration
- 1h 46m
- When
- Every day
- Estimated price
- $45–300
Flights from Portland to Laguardia Airport
- Ave. Duration
- 1h 34m
- When
- Every day
- Estimated price
- $50–330
Flights from Portland to John F. Kennedy International Airport
- Ave. Duration
- 1h 34m
- When
- Every day
- Estimated price
- $55–360
Flights from Bangor to John F. Kennedy International Airport
- Ave. Duration
- 1h 50m
- When
- Every day
- Estimated price
- $50–320
- Website
- united.com
Flights from Portland to Newark Liberty International Airport
- Ave. Duration
- 1h 41m
- When
- Every day
- Estimated price
- $45–310
Flights from Bangor to Newark Liberty International Airport
- Ave. Duration
- 1h 58m
- When
- Every day
- Estimated price
- $45–280
- Website
- aa.com
Flights from Bangor to Laguardia Airport
- Ave. Duration
- 1h 34m
- When
- Every day
- Estimated price
- $45–300
Flights from Portland to Laguardia Airport
- Ave. Duration
- 1h 23m
- When
- Every day
- Estimated price
- $50–330
- Website
- jetblue.com
Flights from Portland to John F. Kennedy International Airport
- Ave. Duration
- 1h 20m
- When
- Tuesday and Sunday
- Estimated price
- $55–360
Rome2Rio's guide to Amtrak Northeast Regional
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Boston to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 4h 2m
- Frequency
- Every 3 hours
- Estimated price
- $30–300
- Website
- https://www.amtrak.com/home.html
- Schedules at
- https://www.amtrak.com/northeast-regional-train
- Coach
- $30–300
- Business Class
- $95–360
Rome2Rio's guide to Amtrak Acela
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Boston to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 3h 41m
- Frequency
- Every 4 hours
- Estimated price
- $50–750
- Schedules at
- https://www.amtrak.com/acela-train
- Website
- https://www.amtrak.com/home.html
- Business Class
- $50–490
- First Class
- $200–750
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Ny Moynihan Train Hall At Penn Station to Poughkeepsie Amtrak Station
- Ave. Duration
- 1h 25m
- Frequency
- Every 2 hours
- Estimated price
- $30–75
- Website
- https://www.amtrak.com/home.html
Train from Boston to Pittsfield Amtrak Station
- Ave. Duration
- 3h 52m
- Frequency
- Once daily
- Estimated price
- $19–85
- Website
- https://www.amtrak.com/home.html
- Coach Seat - Advance Purchase
- $23–40
- Coach Seat short notice purchase
- $19–85
- Business - advance purchase
- $26–140
- Business Class
- $40–220
Train from Pittsfield Amtrak Station to Poughkeepsie Amtrak Station
- Ave. Duration
- 2h 22m
- Frequency
- Once a week
- Estimated price
- $15–75
- Website
- https://www.amtrak.com/home.html
- Coach Seat - Advance Purchase
- $21–35
- Coach Seat short notice purchase
- $15–75
- Business - advance purchase
- $20–120
- Business Class
- $35–200
Train from Portland to Boston
- Ave. Duration
- 2h 32m
- Frequency
- Every 4 hours
- Estimated price
- $34–39
- Website
- https://www.amtrak.com/home.html
- Phone
- 877.690.5114
- Website
- mta.info
Train from Grand Central Terminal to Poughkeepsie
- Ave. Duration
- 1h 50m
- Frequency
- Hourly
- Estimated price
- $18–27
- Website
- https://www.mta.info/agency/metro-north-railroad
- Schedules at
- https://www.mta.info/schedules
- Off-Peak
- $18–20
- Peak
- $23–27
Train from 125th Street - Harlem to Poughkeepsie
- Ave. Duration
- 1h 39m
- Frequency
- Hourly
- Estimated price
- $17–26
- Website
- https://www.mta.info/agency/metro-north-railroad
- Schedules at
- https://www.mta.info/schedules
- Off-Peak
- $17–19
- Peak
- $23–26
- Phone
- +1 800 639 3317
- info@concordcoachlines.com
- Website
- concordcoachlines.com
Bus from Colby College Museum of Art to Boston, MA - South Station
- Ave. Duration
- 3h 45m
- Frequency
- Twice a week
- Estimated price
- $40–55
- Website
- https://concordcoachlines.com
Bus from Augusta Transportation Center to Portland Transportation Center
- Ave. Duration
- 1h 15m
- Frequency
- Every 2 hours
- Estimated price
- $13–17
- Website
- https://concordcoachlines.com
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Boston to New York Midtown
- Ave. Duration
- 4h 25m
- Frequency
- Every 2 hours
- Estimated price
- $30–85
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Waterville to Bangor Park & Ride
- Ave. Duration
- 54 min
- Frequency
- Once daily
- Estimated price
- $24–55
- Website
- https://www.greyhound.com/
Bus from Boston to White Plains Bus Station
- Ave. Duration
- 4h 45m
- Frequency
- Once daily
- Estimated price
- $40–70
- Website
- https://www.greyhound.com/
Bus from Waterville to City of Portland
- Ave. Duration
- 2h
- Frequency
- Once daily
- Estimated price
- $27–60
- Website
- https://www.greyhound.com/
Rome2Rio's guide to Amtrak Thruway
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Augusta Transportation Center to Portland Transportation Center
- Ave. Duration
- 1h 15m
- Frequency
- 5 times a day
- Estimated price
- $13–45
- Website
- https://www.amtrak.com/home.html
- Adult
- $13–45
- Phone
- +1 800-624-4217
- info@leprechaunlines.com
- Website
- leprechaunlines.com
Bus from TransCenter to Metro North Station
- Ave. Duration
- 1h 48m
- Frequency
- 5 times a day
- Estimated price
- $1–9
- Schedules at
- leprechaunlines.com
- Newburgh - Beacon Shuttle
- $1
- Newburgh Local
- $2
- White Plains Commuter
- $7–9
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