There are 11 ways to get from Waterville to Louisville by bus, plane, bus (Flixbus), train, car, taxi, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus to Portland, fly to Louisville International Airport
best- Take the bus from Waterville to City of Portlandbus
- Fly from Portland (PWM) to Louisville International Airport (SDF)plane PWM - SDF
10h 31m$188–877Bus
cheapest- Take the bus from Colby College Museum of Art to Boston, MA - South Stationbus
- Take the bus from South Station to Port Authority Bus Terminalbus
- Take the bus from Port Authority Bus Terminal to Wilson & Ferrell Shell Station - Columbusbus
- Take the bus from N Wilson Rd & Ferrell Pl - Columbus to Louisville, KY Bus Stationbus
29h 23m$162–324Bus via Columbus
- Take the bus from Colby College Museum of Art to Boston, MA - South Stationbus
- Take the bus from Boston to New York City Chinatownbus
- Take the bus from New York, NY to Columbus, OHbus Nyc
- Take the bus from Columbus - Downtown - Mound St to Louisville, KY Bus Stationbus
25h 57m$209–289Bus, train via Toledo
- Take the bus from Colby College Museum of Art to Boston, MA - South Stationbus
- Take the train from Boston to Toledotrain
- Take the bus from Toledo to Indianapolis, INbus
- Take the bus from Indianapolis Union Station to Louisville, KYbus
30h 42m$191–874Drive 1,109.6 mi
- Drive from Waterville to Louisvillecar 1,109.6 mi
19h 50m$203–293Bus to Boston Logan Airport, fly to Louisville International Airport
- Take the bus from Colby College Museum of Art to Logan International Airportbus
- Fly from Boston Logan Airport (BOS) to Louisville International Airport (SDF)plane BOS - SDF
8h 54m$214–617Bus to Bangor, fly to Louisville International Airport
- Take the bus from Waterville to Bangor Park & Ridebus
- Fly from Bangor (BGR) to Louisville International Airport (SDF)plane BGR - SDF
9h 52m$163–777Fly Augusta State Airport to Louisville International Airport
- Fly from Augusta State Airport (AUG) to Louisville International Airport (SDF)plane AUG - SDF
8h 53m$174–639Taxi to Rockland, fly to Louisville International Airport
- Take the taxi from Waterville to Rockland (RKD)taxi
- Fly from Rockland (RKD) to Louisville International Airport (SDF)plane RKD - SDF
11h 39m$314–1,110Bus to Boston Logan Airport, fly to Covington, bus
- Take the bus from Colby College Museum of Art to Logan International Airportbus
- Fly from Boston Logan Airport (BOS) to Covington (CVG)plane BOS - CVG
- Take the bus from Cincinnati - Downtown to Louisville, KY Bus Stationbus
11h 39m$184–861Bus, train
- Take the bus from Colby College Museum of Art to Boston, MA - South Stationbus
- Take the train from Boston to Ny Moynihan Train Hall At Penn Stationtrain
- Take the train from Ny Moynihan Train Hall At Penn Station to Indianapolistrain
- Take the bus from Indianapolis Union Station to Louisville, KYbus
35h 31m$220–1,129
Portland (PWM) to Louisville International Airport (SDF) flights
Questions & Answers
The cheapest way to get from Waterville to Louisville is to bus which costs $160 - $330 and takes 29h 23m.
The fastest way to get from Waterville to Louisville is to fly which takes 8h 53m and costs $170 - $650.
The distance between Waterville and Louisville is 989 miles. The road distance is 1116.1 miles.
The best way to get from Waterville to Louisville without a car is to bus via Columbus which takes 25h 57m and costs $200 - $290.
It takes approximately 10h 31m to get from Waterville to Louisville, including transfers.
The best way to get from Waterville to Louisville is to bus via Columbus which takes 25h 57m and costs $200 - $290. Alternatively, you can fly, which costs $170 - $650 and takes 8h 53m.
Yes, the driving distance between Waterville to Louisville is 1116 miles. It takes approximately 19h 50m to drive from Waterville to Louisville.
There are 596+ hotels available in Louisville.
What companies run services between Waterville, ME, USA and Louisville, KY, USA?
You can take a vehicle from Waterville to Louisville, KY Bus Station via Colby College Museum of Art, Boston, MA - South Station, Boston, New York City Chinatown, New York, NY, Columbus, OH, and Columbus - Downtown - Mound St in around 25h 57m. Alternatively, Cape Air, Southwest Airlines, and two other airlines fly from Augusta State Airport (AUG) to Louisville International Airport (SDF) twice daily.
- Website
- delta.com
Flights from Portland to Louisville International Airport via Detroit
- Ave. Duration
- 6h 1m
- When
- Tuesday, Wednesday, and Saturday
- Estimated price
- $150–800
Flights from Boston Logan Airport to Louisville International Airport
- Ave. Duration
- 2h 47m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $100–600
Flights from Boston Logan Airport to Louisville International Airport via Detroit
- Ave. Duration
- 5h 16m
- When
- Tuesday, Wednesday, and Saturday
- Estimated price
- $110–650
Flights from Bangor to Louisville International Airport via New York La Guardia
- Ave. Duration
- 6h 40m
- When
- Monday to Friday
- Estimated price
- $130–700
Flights from Boston Logan Airport to Covington
- Ave. Duration
- 2h 40m
- When
- Every day
- Estimated price
- $130–750
Flights from Boston Logan Airport to Covington via Detroit
- Ave. Duration
- 4h 47m
- When
- Every day
- Estimated price
- $140–800
Flights from Boston Logan Airport to Covington via New York La Guardia
- Ave. Duration
- 4h 52m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $130–750
- Website
- aa.com
Flights from Boston Logan Airport to Louisville International Airport
- Ave. Duration
- 3h
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $100–600
Flights from Boston Logan Airport to Louisville International Airport via Reagan Washington
- Ave. Duration
- 5h 3m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $110–600
Flights from Bangor to Louisville International Airport via Reagan Washington
- Ave. Duration
- 7h 38m
- When
- Every day
- Estimated price
- $130–700
Flights from Bangor to Louisville International Airport via Charlotte
- Ave. Duration
- 6h 50m
- When
- Every day
- Estimated price
- $150–750
Flights from Bangor to Louisville International Airport via Philadelphia
- Ave. Duration
- 8h 37m
- When
- Every day
- Estimated price
- $130–700
Flights from Rockland to Louisville International Airport via Boston Logan Airport
- Ave. Duration
- 17h 49m
- When
- Monday, Tuesday, Wednesday, Thursday, Saturday, and Sunday
- Estimated price
- $180–950
Flights from Boston Logan Airport to Covington
- Ave. Duration
- 2h 50m
- When
- Every day
- Estimated price
- $130–750
Flights from Boston Logan Airport to Covington via Reagan Washington
- Ave. Duration
- 4h 39m
- When
- Saturday
- Estimated price
- $140–750
- Website
- united.com
Flights from Portland to Louisville International Airport via Washington Dulles
- Ave. Duration
- 5h 10m
- When
- Every day
- Estimated price
- $150–800
Flights from Boston Logan Airport to Louisville International Airport via Washington Dulles
- Ave. Duration
- 5h 20m
- When
- Every day
- Estimated price
- $110–600
Flights from Bangor to Louisville International Airport via Newark
- Ave. Duration
- 6h 1m
- When
- Wednesday
- Estimated price
- $130–700
Flights from Augusta State Airport to Louisville International Airport via Boston Logan Airport, Washington Dulles
- Ave. Duration
- 8h 20m
- When
- Every day
- Estimated price
- $100–550
Flights from Rockland to Louisville International Airport via Boston Logan Airport, Washington Dulles
- Ave. Duration
- 8h 58m
- When
- Every day
- Estimated price
- $180–950
Flights from Boston Logan Airport to Covington via Washington Dulles
- Ave. Duration
- 4h 46m
- When
- Every day
- Estimated price
- $130–750
Flights from Boston Logan Airport to Covington via Montreal
- Ave. Duration
- 4h 55m
- When
- Every day
- Estimated price
- $150–800
- Website
- southwest.com
Flights from Portland to Louisville International Airport via Baltimore
- Ave. Duration
- 6h 50m
- When
- Monday, Thursday, and Friday
- Estimated price
- $150–800
Flights from Boston Logan Airport to Louisville International Airport via Baltimore
- Ave. Duration
- 4h 40m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $110–600
Flights from Augusta State Airport to Louisville International Airport via Boston Logan Airport, Baltimore
- Ave. Duration
- 7h 26m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $100–550
Flights from Rockland to Louisville International Airport via Boston Logan Airport, Baltimore
- Ave. Duration
- 12h
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $180–950
Flights from Boston Logan Airport to Covington via Baltimore
- Ave. Duration
- 4h 30m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $130–750
- Website
- aircanada.com
Flights from Boston Logan Airport to Covington via Montreal
- Ave. Duration
- 4h 55m
- When
- Every day
- Estimated price
- $150–800
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Boston to Toledo
- Ave. Duration
- 17h 23m
- Frequency
- Once daily
- Estimated price
- $100–700
- Website
- https://www.amtrak.com/home.html
Train from Ny Moynihan Train Hall At Penn Station to Indianapolis
- Ave. Duration
- 22h 35m
- Frequency
- 3 times a week
- Estimated price
- $120–270
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Amtrak Northeast Regional
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Boston to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 4h 2m
- Frequency
- Every 3 hours
- Estimated price
- $30–300
- Website
- https://www.amtrak.com/home
- Schedules at
- https://www.amtrak.com/northeast-regional-train
- Coach
- $30–300
- Business Class
- $95–360
Rome2Rio's guide to Amtrak Acela
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Boston to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 3h 41m
- Frequency
- Every 4 hours
- Estimated price
- $50–750
- Schedules at
- https://www.amtrak.com/acela-train
- Website
- https://www.amtrak.com/home.html
- Business Class
- $50–490
- First Class
- $200–750
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Waterville to City of Portland
- Ave. Duration
- 2h
- Frequency
- Once daily
- Estimated price
- $27–60
- Website
- https://www.greyhound.com/
Bus from Waterville to Bangor Park & Ride
- Ave. Duration
- 54 min
- Frequency
- Once daily
- Estimated price
- $24–55
- Website
- https://www.greyhound.com/
Bus from South Station to Port Authority Bus Terminal
- Ave. Duration
- 4h 45m
- Frequency
- Hourly
- Estimated price
- $30–55
- Website
- https://www.greyhound.com/
Bus from Port Authority Bus Terminal to Wilson & Ferrell Shell Station - Columbus
- Ave. Duration
- 14h 10m
- Frequency
- 3 times a day
- Estimated price
- $65–140
- Website
- https://www.greyhound.com/
- Phone
- +1 800 639 3317
- info@concordcoachlines.com
- Website
- concordcoachlines.com
Bus from Colby College Museum of Art to Boston, MA - South Station
- Ave. Duration
- 3h 45m
- Frequency
- Twice a week
- Estimated price
- $40–55
- Website
- https://concordcoachlines.com
Bus from Colby College Museum of Art to Logan International Airport
- Ave. Duration
- 3h 45m
- Frequency
- Twice a week
- Estimated price
- $35–55
- Website
- https://concordcoachlines.com
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Boston to New York City Chinatown
- Ave. Duration
- 5h
- Frequency
- Every 4 hours
- Estimated price
- $30–55
- Schedules at
- flixbus.com
- Phone
- +1 917.398.0398
- Website
- skyhorsebus.com
Bus from New York, NY to Columbus, OH
- Ave. Duration
- 9h 31m
- Frequency
- Once daily
- Estimated price
- $110
- Schedules at
- https://www.gotobus.com/jaguar-bus/
- Phone
- +1 888-378-3823
- info@baronsbus.com
- Website
- baronsbus.com
Bus from Columbus - Downtown - Mound St to Louisville, KY Bus Station
- Ave. Duration
- 4h 26m
- Frequency
- Once daily
- Estimated price
- $21–60
- Website
- https://baronsbus.com
Bus from Toledo to Indianapolis, IN
- Ave. Duration
- 4h 5m
- Frequency
- Once daily
- Estimated price
- $21–65
- Website
- https://baronsbus.com
Bus from Cincinnati - Downtown to Louisville, KY Bus Station
- Ave. Duration
- 2h 4m
- Frequency
- Once daily
- Estimated price
- $9–45
- Website
- https://baronsbus.com
Bus from N Wilson Rd & Ferrell Pl - Columbus to Louisville, KY Bus Station
- Ave. Duration
- 4h 18m
- Frequency
- Once daily
- Estimated price
- $20–60
- Website
- https://baronsbus.com
Rome2Rio's guide to Amtrak Thruway
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Indianapolis Union Station to Louisville, KY
- Ave. Duration
- 2h 25m
- Frequency
- Twice daily
- Estimated price
- $22–45
- Website
- https://www.amtrak.com/home.html
- Adult
- $22–45
- Phone
- 1-800-343-9999
- Website
- peterpanbus.com
Bus from South Station to Port Authority Bus Terminal
- Ave. Duration
- 4h 35m
- Frequency
- Every 2 hours
- Estimated price
- $29–60
- Website
- https://peterpanbus.com
- Adult
- $29–60
- Ave. Duration
- 1h 30m
- Estimated price
- $130–160
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