• Our partners include:

  • Greyhound USA
  • VIA Rail
  • Amtrak
  • Acela Express
  • Megabus
  • SuperShuttle
  • Booking.com
  • Skyscanner
  • Airbnb
  • Expedia

There are 9 ways to get from Washington to Mayo Clinic by plane, shuttle, train, bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly Reagan Washington to Rochester  •  6h 54m

  1. Fly from Reagan Washington (DCA) to Rochester (RST) DCA - RST

$200 - $864

Cheapest option

Bus  •  29h 28m

  1. Take the bus from Washington, Dc to Chicago, Il
  2. Take the bus from Chicago, Il to Milwaukee, Wi
  3. Take the bus from Milwaukee to Rochester, MN 966

$145 - $300

7 alternative options

Fly Reagan Washington to Minneapolis, shuttle  •  6h 6m

  1. Fly from Reagan Washington (DCA) to Minneapolis (MSP) DCA - MSP
  2. Take a shuttle bus from Terminal 2 MSP to 2nd Street Rochester

$155 - $521

Train to Baltimore, fly to Minneapolis, shuttle  •  6h 20m

  1. Take the train from Washington Union Station to BWI Marshall Airport Amtrak Station
  2. Fly from Baltimore (BWI) to Minneapolis (MSP) BWI - MSP
  3. Take a shuttle bus from Terminal 2 MSP to 2nd Street Rochester

$178 - $578

Fly Washington Dulles to Minneapolis, shuttle  •  6h 53m

  1. Fly from Washington Dulles (IAD) to Minneapolis (MSP) IAD - MSP
  2. Take a shuttle bus from Terminal 2 MSP to 2nd Street Rochester

$161 - $478

Fly Reagan Washington to La Crosse, bus  •  8h 32m

  1. Fly from Reagan Washington (DCA) to La Crosse (LSE) DCA - LSE
  2. Take the bus from La Crosse, WI to Rochester, MN

$218 - $1,004

Train, bus  •  26h 10m

  1. Take the train from Washington Union Station to Chicago Union Station
  2. Take the train from Chicago Union Station to Winona Amtrak Station
  3. Take the bus from Winona Amtrak Station to Rochester, MN

$189 - $505

Train, bus via Madison - Langdon & N Park  •  28h 14m

  1. Take the train from Washington Union Station to Chicago Union Station
  2. Take the bus from Chicago to Madison - Langdon & N Park
  3. Take the bus from Madison to Rochester, MN 966

$173 - $401

Drive  •  17h 24m

  1. Drive from Washington to Mayo Clinic 1050 miles

$100 - $150

Questions & Answers

The cheapest way to get from Washington to Mayo Clinic is to drive which costs $100 - $150 and takes 17h 24m.

More details

The quickest way to get from Washington to Mayo Clinic is to fly and shuttle which costs $150 - $550 and takes 6h 6m.

More details

No, there is no direct bus from Washington to Mayo Clinic. However, there are services departing from Washington, Dc and arriving at Rochester, MN via Chicago, Il and Milwaukee. The journey, including transfers, takes approximately 29h 28m.

More details

The distance between Washington and Mayo Clinic is 877 miles. The road distance is 1050 miles.

Get driving directions

The best way to get from Washington to Mayo Clinic without a car is to train and bus which takes 26h 10m and costs $180 - $550.

More details

It takes approximately 6h 54m to get from Washington to Mayo Clinic, including transfers.

More details

Washington to Mayo Clinic bus services, operated by Greyhound USA, depart from Washington, Dc station.

More details

The best way to get from Washington to Mayo Clinic is to fly which takes 6h 54m and costs $200 - $900. Alternatively, you can bus, which costs $140 - $300 and takes 29h 28m.

Mode details

There is no direct flight from Reagan Washington Airport to Rochester Airport. The quickest flight takes 4h 29m and has one stopover.

Search flights

Washington to Mayo Clinic bus services, operated by Jefferson Lines, arrive at Rochester, MN station.

More details

Map of how to get from Washington to Mayo Clinic.
Launch map view
  • Distance: 877.3 miles
  • Duration: 6h 54m

What companies run services between Washington, DC, USA and Mayo Clinic, MN, USA?

American Airlines, United Airlines and Delta fly from Washington to Mayo Clinic hourly. Alternatively, you can take a bus from Washington to Mayo Clinic via Chicago, Il, Milwaukee, Wi, Milwaukee, and Rochester, MN in around 29h 28m.

Airlines
Delta
Website
delta.com
Flights from Reagan Washington to Rochester via Minneapolis
Ave. Duration
5h 11m
When
Every day
Estimated price
$180 - $900
Flights from Reagan Washington to Rochester via Atlanta
Ave. Duration
6h 12m
When
Every day
Estimated price
$210 - $950
Flights from Reagan Washington to Minneapolis
Ave. Duration
2h 51m
When
Every day
Estimated price
$190 - $950
Flights from Reagan Washington to Minneapolis via Detroit
Ave. Duration
4h 45m
When
Every day
Estimated price
$190 - $950
Flights from Baltimore to Minneapolis
Ave. Duration
2h 53m
When
Every day
Estimated price
$150 - $550
Flights from Baltimore to Minneapolis via Detroit
Ave. Duration
4h 41m
When
Saturday and Sunday
Estimated price
$150 - $550
Flights from Baltimore to Minneapolis via Covington
Ave. Duration
4h 59m
When
Monday to Friday
Estimated price
$150 - $550
Flights from Washington Dulles to Minneapolis
Ave. Duration
2h 55m
When
Every day
Estimated price
$190 - $900
Flights from Washington Dulles to Minneapolis via Detroit
Ave. Duration
5h 27m
When
Every day
Estimated price
$190 - $900
Flights from Washington Dulles to Minneapolis via Atlanta
Ave. Duration
5h 30m
When
Every day
Estimated price
$190 - $900
Flights from Reagan Washington to La Crosse via Detroit
Ave. Duration
4h 29m
When
Saturday
Estimated price
$180 - $950
Flights from Reagan Washington to La Crosse via Minneapolis
Ave. Duration
5h 27m
When
Every day
Estimated price
$200 - $950
American Airlines
Website
aa.com
Flights from Reagan Washington to Rochester via Chicago O'Hare
Ave. Duration
5h 15m
When
Every day
Estimated price
$190 - $850
Flights from Reagan Washington to Rochester via Norfolk, Chicago O'Hare
Ave. Duration
6h 52m
When
Monday to Friday
Estimated price
$200 - $900
Flights from Reagan Washington to Rochester via Nashville, Chicago O'Hare
Ave. Duration
6h 57m
When
Monday to Friday
Estimated price
$210 - $900
Flights from Reagan Washington to Rochester via Detroit, Chicago O'Hare
Ave. Duration
7h 2m
When
Monday to Friday
Estimated price
$190 - $850
Flights from Reagan Washington to Rochester via Charlotte, Chicago O'Hare
Ave. Duration
7h 2m
When
Saturday
Estimated price
$210 - $900
Flights from Reagan Washington to Minneapolis
Ave. Duration
2h 59m
When
Every day
Estimated price
$190 - $850
Flights from Reagan Washington to Minneapolis via Chicago O'Hare
Ave. Duration
4h 45m
When
Every day
Estimated price
$190 - $850
Flights from Baltimore to Minneapolis via Chicago O'Hare
Ave. Duration
4h 55m
When
Monday, Thursday, Friday, Saturday and Sunday
Estimated price
$180 - $650
Flights from Washington Dulles to Minneapolis via Charlotte
Ave. Duration
5h 24m
When
Tuesday, Wednesday, Thursday, Friday, Saturday and Sunday
Estimated price
$220 - $900
Flights from Reagan Washington to La Crosse via Chicago O'Hare
Ave. Duration
4h 43m
When
Every day
Estimated price
$200 - $950
Flights from Reagan Washington to La Crosse via Buffalo, Chicago O'Hare
Ave. Duration
6h 53m
When
Sunday
Estimated price
$210 - $950
Flights from Reagan Washington to La Crosse via Nashville, Chicago O'Hare
Ave. Duration
7h 13m
When
Monday, Wednesday, Thursday, Friday, Saturday and Sunday
Estimated price
$230 - $1,000
Flights from Reagan Washington to La Crosse via Rochester, Chicago O'Hare
Ave. Duration
7h 23m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$220 - $950
Flights from Reagan Washington to La Crosse via Cleveland, Chicago O'Hare
Ave. Duration
7h 40m
When
Every day
Estimated price
$200 - $950
Flights from Reagan Washington to La Crosse via Lansing, Chicago O'Hare
Ave. Duration
7h 23m
When
Monday, Wednesday, Thursday, Friday, Saturday and Sunday
Estimated price
$200 - $950
Flights from Reagan Washington to La Crosse via Detroit, Chicago O'Hare
Ave. Duration
7h 34m
When
Every day
Estimated price
$200 - $950
Flights from Reagan Washington to La Crosse via Columbus, Chicago O'Hare
Ave. Duration
7h 34m
When
Saturday
Estimated price
$200 - $950
Flights from Reagan Washington to La Crosse via Charlotte, Chicago O'Hare
Ave. Duration
8h 28m
When
Monday, Wednesday, Thursday, Friday and Sunday
Estimated price
$220 - $1,000
United Airlines
Website
united.com
Flights from Reagan Washington to Rochester via Chicago O'Hare
Ave. Duration
4h 58m
When
Every day
Estimated price
$200 - $900
Flights from Reagan Washington to Minneapolis via Chicago O'Hare
Ave. Duration
4h 43m
When
Monday to Friday
Estimated price
$250 - $1,000
Flights from Baltimore to Minneapolis via Chicago O'Hare
Ave. Duration
4h 39m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$230 - $900
Flights from Baltimore to Minneapolis via Toronto
Ave. Duration
4h 41m
When
Monday to Friday
Estimated price
$210 - $800
Flights from Washington Dulles to Minneapolis
Ave. Duration
2h 48m
When
Every day
Estimated price
$190 - $850
Flights from Washington Dulles to Minneapolis via Chicago O'Hare
Ave. Duration
5h 19m
When
Every day
Estimated price
$190 - $850
Flights from Washington Dulles to Minneapolis via Newark
Ave. Duration
5h 49m
When
Every day
Estimated price
$190 - $850
Southwest Airlines
Website
southwest.com
Flights from Reagan Washington to Minneapolis via Chicago Midway
Ave. Duration
4h 37m
When
Saturday and Sunday
Estimated price
$220 - $850
Flights from Reagan Washington to Minneapolis via St. Louis
Ave. Duration
4h 40m
When
Monday to Friday
Estimated price
$220 - $850
Flights from Baltimore to Minneapolis
Ave. Duration
2h 47m
When
Every day
Estimated price
$160 - $600
Flights from Baltimore to Minneapolis via Chicago Midway
Ave. Duration
4h 40m
When
Every day
Estimated price
$160 - $600
Air Canada
Website
aircanada.com
Flights from Baltimore to Minneapolis via Toronto
Ave. Duration
4h 41m
When
Monday to Friday
Estimated price
$210 - $800
Flights from Washington Dulles to Minneapolis via Chicago O'Hare
Ave. Duration
5h 19m
When
Every day
Estimated price
$190 - $850
Spirit Airlines
Website
spirit.com
Flights from Baltimore to Minneapolis
Ave. Duration
3h
When
Every day
Estimated price
$150 - $550
Train operators
Amtrak Acela Express

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak Acela Express
Contact Details
Phone
+1 215-856-7924
Website
amtrak.com
Train from Washington Union Station to BWI Marshall Airport Amtrak Station
Ave. Duration
21m
Frequency
Hourly
Estimated price
$55 - $150
Website
amtrak.com
Business Seat
$55 - $140
First Class Seat
$120 - $150
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 215-856-7924
Website
amtrak.com
Train from Washington Union Station to Chicago Union Station
Ave. Duration
17h 40m
Frequency
Once daily
Estimated price
$100 - $310
Website
amtrak.com
Coach Seat
$100 - $160
Flexi Coach Seat
$190 - $280
Business Coach Seat
$220 - $310
Room
$440 - $600
Train from Chicago Union Station to Winona Amtrak Station
Ave. Duration
5h 26m
Frequency
3 times a day
Estimated price
$50 - $140
Website
amtrak.com
Coach Seat
$50 - $80
Flexi Coach Seat
$95 - $140
Business Coach Seat
$95 - $140
Room
$240 - $340
Bus operators
Groome Transportation
Phone
(800) 280-9270
Website
groometransportation.com
Shuttle from Terminal 2 MSP to 2nd Street Rochester
Ave. Duration
1h 25m
Frequency
Hourly
Estimated price
$30 - $45
Schedules at
groometransportation.com
Bus from Winona Amtrak Station to Rochester, MN
Ave. Duration
1h 20m
Frequency
Every 3 hours
Estimated price
$25 - $45
Schedules at
groometransportation.com
Jefferson Lines
Phone
800-451-5333
Email
info@jeffersonlines.com
Website
jeffersonlines.com
Bus from La Crosse, WI to Rochester, MN
Ave. Duration
1h 35m
Frequency
Once daily
Estimated price
$22 - $35
Book at
jeffersonlines.com
Bus from Madison to Rochester, MN
Ave. Duration
4h 45m
Frequency
Once daily
Estimated price
$45 - $65
Book at
jeffersonlines.com
Bus from Milwaukee to Rochester, MN
Ave. Duration
6h 10m
Frequency
Once daily
Estimated price
$55 - $80
Book at
jeffersonlines.com
Amtrak Thruway

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak Thruway
Contact Details
Phone
+1 215-856-7924
Website
amtrak.com
Bus from Winona Amtrak Station to Rochester, MN
Ave. Duration
1h 20m
Frequency
Every 4 hours
Estimated price
$18 - $26
Website
amtrak.com
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Washington, Dc to Chicago, Il
Ave. Duration
18h 50m
Frequency
Twice daily
Estimated price
$75 - $190
Website
greyhound.com
Economy
$75 - $120
Flexible
$140 - $190
Bus from Chicago, Il to Milwaukee, Wi
Ave. Duration
2h 20m
Frequency
Every 4 hours
Estimated price
$15 - $35
Website
greyhound.com
Economy
$15 - $23
Flexible
$28 - $35

Want to know more about travelling around United States

Rome2rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

More Questions & Answers

Yes, the driving distance between Washington to Mayo Clinic is 1050 miles. It takes approximately 17h 24m to drive from Washington to Mayo Clinic.

Get driving directions

United Airlines, Delta and American Airlines offer flights from Reagan Washington Airport to Rochester Airport.

Search flights

There are 57+ hotels available in Mayo Clinic. Prices start at $72 USD per night.

More details

The best way to get from Washington to Reagan Washington Airport is to subway which takes 15m and costs $2 - $4.

More details