There are 6 ways to get from Washington University in St. Louis to Chicago by plane, bus, train or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly to Chicago Midway  •  3 h 16 min

  1. Fly from St. Louis (STL) to Chicago Midway (MDW) STL - MDW

$124 - $306

Cheapest option

Bus Megabus  •  6 h 55 min

  1. Take the bus from St Louis, MO to Chicago, IL via St Louis

$32 - $42

4 alternative options

Fly to Chicago O'Hare  •  3 h 42 min

  1. Fly from St. Louis (STL) to Chicago O'Hare (ORD) STL - ORD

$90 - $248

Train  •  7 h

  1. Take the train from St. Louis Gateway Station Amtrak to Chicago Union Station Amtrak Lincoln Service / ...

$52 - $132

Bus Greyhound USA  •  9 h 39 min

  1. Take the bus from St Louis Lambert Fld to Chicago, Il 1364

$40 - $95

Drive  •  4 h 56 min

  1. Drive from Washington University in St. Louis to Chicago 305.1 miles

$29 - $45

Questions & Answers

The cheapest way to get from Washington University in St. Louis to Chicago is to drive which costs $29 - $45 and takes 4 h 56 min.

More details

The quickest way to get from Washington University in St. Louis to Chicago is to fly which costs $120 - $310 and takes 3 h 16 min.

More details

The distance between Washington University in St. Louis and Chicago is 265 miles. The road distance is 305.1 miles.

Get driving directions

It takes approximately 3 h 16 min to get from Washington University in St. Louis to Chicago, including transfers.

More details

No, there is no direct train from Washington University in St. Louis station to Chicago station. However, there are services departing from SKINKER station and arriving at Chicago Union Station Amtrak via St. Louis Gateway Station Amtrak. The journey, including transfers, takes approximately 7 h.

More details

What companies run services between Washington University in St. Louis, MO, USA and Chicago, IL, USA?

Southwest Airlines flies from Washington University in St. Louis to Chicago every 4 hours. Alternatively, Megabus operates a bus from Washington University in St. Louis to Chicago twice daily. Tickets cost $29 - $40 and the journey takes 5 h 30 min.

Airlines
Southwest Airlines
Website
southwest.com
Flights from St. Louis to Chicago Midway
Ave. Duration
1 h 3 min
When
Every day
Estimated price
$160 - $550
United Airlines
Website
united.com
Flights from St. Louis to Chicago O'Hare
Ave. Duration
1 h 22 min
When
Every day
Estimated price
$120 - $650
American Airlines
Website
aa.com
Flights from St. Louis to Chicago O'Hare
Ave. Duration
1 h 24 min
When
Every day
Estimated price
$120 - $550
Train operators
Amtrak
Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from St. Louis Gateway Station Amtrak to Chicago Union Station Amtrak
Ave. Duration
5 h 40 min
Frequency
Every 4 hours
Estimated price
$50 - $130
Website
amtrak.com
Coach Seat
$50 - $75
Flexi Coach Seat
$90 - $130
Business Coach Seat
$90 - $130
Room
$230 - $320
Bus operators
Greyhound USA
Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from St Louis Lambert Fld to Chicago, Il
Ave. Duration
8 h 30 min
Frequency
Hourly
Estimated price
$35 - $90
Website
greyhound.com
Economy
$35 - $60
Flexible
$65 - $90

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Trips from Washington University in St. Louis