There are 6 ways to get from Waltham to Buffalo by plane, bus (Greyhound, Flixbus), train (Amtrak), car, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Buffalo Niagara International Airport
best- Fly from Boston Logan Airport (BOS) to Buffalo Niagara International Airport (BUF)plane BOS - BUF
4h 59m$141–1,017Bus via BNIA Driveway & BNIA Terminal
cheapest- Take the bus from Boston, MA to Syracuse, NYbus OurBus
- Take the bus from Syracuse, NY to Buffalo, NYbus OurBus
13h 12m$50–167Bus
- Take the bus from Boston to Syracuse Bus Stationbus Greyhound US0270
- Take the bus from Syracuse Bus Station to Buffalobus FlixBus 2686 / ...
12h 3m$72–159Train (Amtrak)
- Take the train from Boston to Buffalo Depew Stationtrain Lake Shore Limited
14h 5m$96–389Drive 445.5 mi
- Drive from Waltham to Buffalocar 445.5 mi
7h 45m$82–118Fly to Rochester, bus
- Fly from Boston Logan Airport (BOS) to Rochester (ROC)plane BOS - ROC
- Take the bus from Rochester, NY to Buffalo, NYbus
7h$201–662
Waltham to Buffalo by bus
Questions & Answers
The cheapest way to get from Waltham to Buffalo is to bus via BNIA Driveway & BNIA Terminal which costs $45 - $170 and takes 13h 12m.
The fastest way to get from Waltham to Buffalo is to fly which takes 4h 59m and costs $140 - $1,100.
No, there is no direct bus from Waltham station to Buffalo. However, there are services departing from Carter St opp Commuter Rail Station and arriving at Buffalo via Boston and Syracuse Bus Station. The journey, including transfers, takes approximately 12h 3m.
The distance between Waltham and Buffalo is 423 miles. The road distance is 448.1 miles.
The best way to get from Waltham to Buffalo without a car is to bus which takes 12h 3m and costs $70 - $160.
It takes approximately 4h 59m to get from Waltham to Buffalo, including transfers.
Waltham to Buffalo bus services, operated by Greyhound USA, depart from Boston station.
The best way to get from Waltham to Buffalo is to fly which takes 4h 59m and costs $140 - $1,100. Alternatively, you can bus, which costs $70 - $160 and takes 12h 3m, you could also train, which costs $95 - $390 and takes 14h 5m.
Waltham to Buffalo bus services, operated by Greyhound USA, arrive at Syracuse Bus Station.
Yes, the driving distance between Waltham to Buffalo is 448 miles. It takes approximately 7h 45m to drive from Waltham to Buffalo.
What companies run services between Waltham, MA, USA and Buffalo, NY, USA?
American Airlines, JetBlue Airways, and three other airlines fly from Boston Logan Airport (BOS) to Buffalo Niagara International Airport (BUF) every 3 hours. Alternatively, you can take a bus from Carter St opp Commuter Rail Station to Buffalo via Lincoln St @ Essex St, Boston, and Syracuse Bus Station in around 12h 3m.
- Website
- delta.com
Flights from Boston Logan Airport to Buffalo Niagara International Airport via New York La Guardia
- Ave. Duration
- 4h
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $140–900
Flights from Boston Logan Airport to Rochester via New York La Guardia
- Ave. Duration
- 4h 3m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $80–550
Flights from Boston Logan Airport to Rochester via New York JFK
- Ave. Duration
- 4h 3m
- When
- Every day
- Estimated price
- $80–550
- Website
- jetblue.com
Flights from Boston Logan Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 41m
- When
- Every day
- Estimated price
- $130–900
Flights from Boston Logan Airport to Buffalo Niagara International Airport via New York JFK
- Ave. Duration
- 3h 59m
- When
- Every day
- Estimated price
- $150–900
Flights from Boston Logan Airport to Rochester via New York JFK
- Ave. Duration
- 3h 59m
- When
- Every day
- Estimated price
- $80–550
- Website
- aa.com
Flights from Boston Logan Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 47m
- When
- Sunday
- Estimated price
- $130–900
Flights from Boston Logan Airport to Buffalo Niagara International Airport via New York La Guardia
- Ave. Duration
- 4h 3m
- When
- Sunday
- Estimated price
- $140–900
Flights from Boston Logan Airport to Buffalo Niagara International Airport via Reagan Washington
- Ave. Duration
- 4h 16m
- When
- Friday
- Estimated price
- $180–1,000
Flights from Boston Logan Airport to Rochester
- Ave. Duration
- 1h 41m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $70–480
- Website
- southwest.com
Flights from Boston Logan Airport to Buffalo Niagara International Airport via Baltimore
- Ave. Duration
- 3h 50m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $170–1,000
Flights from Boston Logan Airport to Rochester via Baltimore
- Ave. Duration
- 4h 5m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $100–600
- Website
- united.com
Flights from Boston Logan Airport to Buffalo Niagara International Airport via Newark
- Ave. Duration
- 4h 15m
- When
- Every day
- Estimated price
- $140–900
Flights from Boston Logan Airport to Rochester via Newark
- Ave. Duration
- 4h 2m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $80–550
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Boston to Buffalo Depew Station
- Ave. Duration
- 11h 32m
- Frequency
- Once daily
- Estimated price
- $85–310
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Boston to Syracuse Bus Station
- Ave. Duration
- 6h 40m
- Frequency
- Once daily
- Estimated price
- $45–110
- Website
- https://www.greyhound.com/
Bus from Syracuse Bus Station to Buffalo
- Ave. Duration
- 3h 20m
- Frequency
- 4 times a day
- Estimated price
- $27–45
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Boston to Syracuse Bus Station
- Ave. Duration
- 6h 45m
- Frequency
- 5 times a week
- Estimated price
- $45–110
- Schedules at
- flixbus.com
Bus from Syracuse Bus Station to Buffalo
- Ave. Duration
- 2h 55m
- Frequency
- Every 4 hours
- Estimated price
- $26–40
- Schedules at
- flixbus.com
- Phone
- +1 800-858-8555
- Website
- trailways.com
Bus from Syracuse Bus Station to Buffalo
- Ave. Duration
- 3h 10m
- Frequency
- 4 times a day
- Estimated price
- $25–35
- Website
- https://trailways.com
- Schedules at
- https://trailways.com/schedules/
- Phone
- +1-844-800-6828
- pr@ourbus.com
- Website
- ourbus.com
Bus from Rochester, NY to Buffalo, NY
- Ave. Duration
- 1h
- Frequency
- Once daily
- Estimated price
- $20–55
- Website
- https://www.ourbus.com
Bus from Boston, MA to Syracuse, NY
- Ave. Duration
- 6h 25m
- Frequency
- Twice a week
- Estimated price
- $20–90
- Website
- https://www.ourbus.com
Bus from Syracuse, NY to Buffalo, NY
- Ave. Duration
- 2h 45m
- Frequency
- 4 times a week
- Estimated price
- $20–65
- Website
- https://www.ourbus.com
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