There are 4 ways to get from Varadero to Cayo Santa María by bus, train, car or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Bus  •  6 h 32 min

  1. Take the bus from Varadero to Santa Clara Viazul
  2. Take the bus from Santa Clara to Cayo Santa María Viazul

$26 - $43

3 alternative options

Train, bus  •  6 h 59 min

  1. Take the train from Matanzas to Santa Clara Cienfuegos/La Habana
  2. Take the bus from Santa Clara to Cayo Santa María Viazul

Drive  •  4 h 22 min

  1. Drive from Varadero to Cayo Santa María 202.8 miles

Fly, bus  •  9 h 37 min

  1. Fly from Varadero (VRA) to Santa Clara (SNU) VRA - SNU
  2. Take the bus from Santa Clara to Cayo Santa María

$450 - $3,647

Questions & Answers

The cheapest way to get from Varadero to Cayo Santa María is to bus which costs $26 - $45 and takes 6 h 32 min.

More details

The quickest way to get from Varadero to Cayo Santa María is to bus which costs $26 - $45 and takes 6 h 32 min.

More details

The distance between Varadero and Cayo Santa María is 233 km. The road distance is 324.4 km.

Get driving directions

It takes approximately 6 h 32 min to get from Varadero to Cayo Santa María, including transfers.

More details

What companies run services between Varadero, Cuba and Cayo Santa María, Sancti Spíritus, Cuba?

You can take a bus from Varadero to Cayo Santa María via Varadero and Santa Clara in around 6 h 32 min.

Airlines
Sunwing Airlines
Website
sunwing.ca
Flights from Varadero to Santa Clara via Cayo
Ave. Duration
6 h 22 min
When
Thursday
Estimated price
$35 - $240
American Airlines
Website
aa.com
Flights from Varadero to Santa Clara via Miami
Ave. Duration
4 h 20 min
When
Every day
Estimated price
$150 - $800
Train operators
Ferrocarriles de Cuba
Website
en.wikipedia.org
Train from Matanzas to Santa Clara
Ave. Duration
2 h 58 min
Frequency
On demand
Schedules at
seat61.com
Bus operators
Viazul
Phone
+ 53 (07) 8836092
Email
sales@viazul.com
Website
viazul.com
Bus from Varadero to Santa Clara
Ave. Duration
3 h 5 min
Frequency
Once daily
Estimated price
$12 - $17
Schedules at
viazul.com
Bus from Santa Clara to Cayo Santa María
Ave. Duration
2 h 25 min
Frequency
Once daily
Estimated price
$7 - $17
Schedules at
viazul.com

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