There are 3 ways to get from Varadero to Cayo Santa María by bus, train or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Bus  •  6 h 32 min

  1. Take the bus from Varadero to Santa Clara Viazul
  2. Take the bus from Santa Clara to Cayo Santa María Viazul

$25 - $43

2 alternative options

Train, bus  •  9 h 52 min

  1. Take the train from Matanzas to Santa Clara La Habana/Cienfuegos / ...
  2. Take the bus from Santa Clara to Cayo Santa María Viazul

$44 - $64

Drive  •  4 h 22 min

  1. Drive from Varadero to Cayo Santa María 202.8 miles

Questions & Answers

The distance between Varadero and Cayo Santa María is 233 km. The road distance is 324.4 km.

Get driving directions

The best way to get from Varadero to Cayo Santa María without a car is to bus which takes 6 h 32 min and costs .

More details

It takes approximately 6 h 32 min to get from Varadero to Cayo Santa María, including transfers.

More details

Yes, the driving distance between Varadero to Cayo Santa María is 324 km. It takes approximately 4 h 22 min to drive from Varadero to Cayo Santa María.

Get driving directions

There are six+ hotels available in Cayo Santa María. Prices start at $100 USD per night.

More details

Map of how to get from Varadero to Cayo Santa María.
Launch map view
  • Distance: 145.5 miles
  • Duration: 6 h 32 min

What companies run services between Varadero, Cuba and Cayo Santa María, Sancti Spíritus, Cuba?

You can take a bus from Varadero to Cayo Santa María via Varadero and Santa Clara in around 6 h 32 min.

Train operators
Ferrocarriles de Cuba
Website
en.wikipedia.org
Train from Matanzas to Santa Clara
Ave. Duration
5 h 51 min
Frequency
On demand
Estimated price
$5 - $9
Schedules at
seat61.com
Bus operators
Viazul
Phone
+ 53 (07) 8836092
Email
sales@viazul.com
Website
viazul.com
Bus from Varadero to Santa Clara
Ave. Duration
3 h 5 min
Frequency
Once daily
Estimated price
$11 - $17
Schedules at
viazul.com
Bus from Santa Clara to Cayo Santa María
Ave. Duration
2 h 25 min
Frequency
Once daily
Estimated price
$7 - $17
Schedules at
viazul.com

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