• Our partners include:

  • Booking.com
  • Skyscanner
  • Airbnb
  • Expedia
  • Uber
  • Rentalcars.com

There are 7 ways to get from Uyuni to Santiago by bus, plane or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Bus to Calama, fly  •  12 h 11 min

  1. Take the bus from Uyuni to Calama
  2. Fly from Calama (CJC) to Santiago (SCL) CJC - SCL

$88 - $552

Cheapest option

Bus Turbus  •  29 h 59 min

  1. Take the bus from Uyuni to Calama Uyuni
  2. Take the bus from Calama to Santiago Alameda Calama

$45 - $97

5 alternative options

Fly from Uyuni  •  7 h 7 min

  1. Fly from Uyuni (UYU) to Santiago (SCL) UYU - SCL

$521 - $4,157

Bus, bus to Antofagasta, fly  •  15 h 24 min

  1. Take the bus from Uyuni to Calama
  2. Take the bus from Calama to Antofagasta
  3. Fly from Antofagasta (ANF) to Santiago (SCL) ANF - SCL

$83 - $516

Bus Pluss Chile  •  30 h 35 min

  1. Take the bus from Uyuni to Calama Uyuni
  2. Take the bus from Calama to Santiago - San Borja Santiago - Calama

$45 - $102

Bus via San Pedro de Atacama  •  33 h 42 min

  1. Take the bus from Uyuni to San Pedro de Atacama Uyuni
  2. Take the bus from San Pedro de Atacama to Santiago Alameda San Pedro

$56 - $104

Drive  •  27 h 31 min

  1. Drive from Uyuni to Santiago 1220.3 miles

$200 - $300

Questions & Answers

The cheapest way to get from Uyuni to Santiago is to bus which costs $45 - $110 and takes 30 h 35 min.

More details

The quickest way to get from Uyuni to Santiago is to fly which costs $500 - $4,200 and takes 7 h 7 min.

More details

No, there is no direct bus from Uyuni to Santiago. However, there are services departing from Uyuni and arriving at Santiago Alameda via Calama. The journey, including transfers, takes approximately 29 h 59 min.

More details

The distance between Uyuni and Santiago is 1493 km. The road distance is 1952.5 km.

Get driving directions

The best way to get from Uyuni to Santiago without a car is to bus which takes 29 h 59 min and costs $45 - $100.

More details

It takes approximately 12 h 11 min to get from Uyuni to Santiago, including transfers.

More details

Uyuni to Santiago bus services, operated by Cruz del Norte, depart from Uyuni station.

More details

The best way to get from Uyuni to Santiago is to fly which takes 7 h 7 min and costs $500 - $4,200. Alternatively, you can bus, which costs $45 - $100 and takes 29 h 59 min.

Mode details

The quickest flight from Calama Airport to Santiago Airport is the direct flight which takes 2 h 1 min.

Search flights

Uyuni to Santiago bus services, operated by Turbus, arrive at Santiago Alameda station.

More details

Map of how to get from Uyuni to Santiago.
Launch map view
  • Distance: 933.4 miles
  • Duration: 12 h 11 min

What companies run services between Uyuni, Potosí, Bolivia and Santiago, Chile?

Amaszonas, LATAM Chile and Boliviana de Aviación fly from Uyuni to Santiago 6 times a week. Alternatively, you can take a bus from Uyuni to Santiago via Calama and Calama in around 29 h 59 min.

Airlines
LATAM Chile
Website
latam.com
Flights from Calama to Santiago
Ave. Duration
2 h 1 min
When
Every day
Estimated price
$190 - $850
Flights from Uyuni to Santiago via La Paz, Iquique
Ave. Duration
7 h
When
Friday
Estimated price
$260 - $1,100
Flights from Antofagasta to Santiago
Ave. Duration
1 h 50 min
When
Every day
Estimated price
$210 - $800
Sky Airline
Website
skyairline.com
Flights from Calama to Santiago
Ave. Duration
2 h 5 min
When
Every day
Estimated price
$80 - $430
Flights from Antofagasta to Santiago
Ave. Duration
1 h 55 min
When
Every day
Estimated price
$50 - $410
JetSMART
Website
jetsmart.com
Flights from Calama to Santiago
Ave. Duration
2 h 1 min
When
Every day
Estimated price
$65 - $400
Flights from Antofagasta to Santiago
Ave. Duration
1 h 50 min
When
Every day
Estimated price
$50 - $330
Bus operators
Cruz del Norte
Phone
+56 (9) 82248119
Email
ventas@turisticointernacionalcruzdelnorte.com
Website
turisticointernacionalcruzdelnorte.com
Bus from Uyuni to Calama
Ave. Duration
8 h
Frequency
Once daily
Estimated price
$15 - $35
Schedules at
turisticointernacionalcruzdelnorte.com
Book at
ticketsbolivia.com.bo
Bus from Uyuni to San Pedro de Atacama
Ave. Duration
10 h 30 min
Frequency
Once daily
Estimated price
$18 - $35
Schedules at
turisticointernacionalcruzdelnorte.com
Book at
ticketsbolivia.com.bo
Pullman Bus
Phone
600 320 3200
Website
pullman.cl
Bus from Calama to Antofagasta
Ave. Duration
2 h 50 min
Frequency
Every 3 hours
Estimated price
$8 - $11
Schedules at
pullman.cl
Bus from Calama to Santiago
Ave. Duration
22 h 10 min
Frequency
5 times a day
Estimated price
$40 - $70
Schedules at
pullman.cl
Pluss Chile
Phone
+56 (2) 26419926
Email
info@plusschile.cl
Website
plusschile.cl
Bus from Calama to Antofagasta
Ave. Duration
3 h 23 min
Frequency
Every 2 hours
Schedules at
plusschile.cl
Book at
altanetpasajes.cl
Bus from Calama to Santiago - San Borja
Ave. Duration
22 h
Frequency
Every 2 hours
Estimated price
$50
Schedules at
plusschile.cl
Book at
altanetpasajes.cl
Ciktur
Phone
951690977
Email
servicioalcliente@ciktur.cl
Website
ciktur.cl
Bus from Calama to Antofagasta
Ave. Duration
5 h
Frequency
Every 4 hours
Schedules at
ciktur.cl
Book at
altanetpasajes.cl
Bus from Calama to Santiago
Ave. Duration
23 h 30 min
Frequency
Every 4 hours
Estimated price
$52
Schedules at
ciktur.cl
Book at
altanetpasajes.cl
Expreso Norte
Website
expresonorte.cl
Bus from Calama to Antofagasta
Ave. Duration
3 h
Frequency
Twice daily
Estimated price
$13 - $19
Schedules at
expresonorte.cl
Bus from Calama to Santiago - San Borja
Ave. Duration
21 h
Frequency
Twice daily
Estimated price
$30 - $70
Schedules at
expresonorte.cl
Semi Cama
$33
Cama
$67
Atacama VIP
Phone
+56 02 720 5206
Website
avip.cl
Bus from Calama to Antofagasta
Ave. Duration
3 h 27 min
Frequency
Once daily
Schedules at
viajaenbus.cl
Turbus
Phone
+56 22 822 7500
Email
atencion_clientes@turbus.cl
Website
turbus.cl
Bus from Calama to Santiago Alameda
Ave. Duration
20 h 55 min
Frequency
5 times a day
Estimated price
$30 - $65
Schedules at
turbus.cl
2nd Class
$30 - $65
Premium
$65 - $100
1st Class
$85 - $130
Bus from San Pedro de Atacama to Santiago Alameda
Ave. Duration
21 h 40 min
Frequency
3 times a day
Estimated price
$35 - $70
Schedules at
turbus.cl
2nd Class
$35 - $70
Premium
$70 - $110
1st Class
$90 - $140

Want to know more about travelling around the world?

Rome2rio's Travel Guide series provide vital information for the global traveller. Read our range of informative guides on popular transport routes and companies - including South Korea: Travelling from Seoul to Busan , Italian Lakes: Getting around by train and Flying into Beijing? - to help you get the most out of your next trip.

More Questions & Answers

Santiago is 1 h ahead of Uyuni. It is currently 4:51 PM in Uyuni and 5:51 PM in Santiago.

Yes, the driving distance between Uyuni to Santiago is 1953 km. It takes approximately 27 h 31 min to drive from Uyuni to Santiago.

Get driving directions

JetSMART, Sky Airline and LATAM Chile offer flights from Calama Airport to Santiago Airport.

Search flights

There are 2145+ hotels available in Santiago. Prices start at $44 USD per night.

More details

The best way to get from Uyuni to Uyuni Airport is to taxi which takes 7 min and costs $10 - $13.

More details