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How to get fromUNION STATION station to Santa Fe Depotby plane, bus (Greyhound, Amtrak), train (Amtrak), car, train or bus

Find Transport to Santa Fe Depot

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There are 5 ways to get from UNION STATION station to Santa Fe Depot by plane, bus (Greyhound, Amtrak), train (Amtrak), car, train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to San Diego International Airport (SAN)planeSTL - SAN
    5h 54m
    $364–488
  2. Train, bus

    cheapest
    1. Take the train from St. Louis to Yuma Amtraktrain
    2. Take the bus from 3rd Street @ Gila Street to William Brook Ave @ B Streetbus95
    3. Take the bus from San Luis Río Colorado to Mexicalibus
    4. Take the bus from Mexicali to Tijuanabus
    2d 14h
    $206–707
  3. Bus

    1. Take the bus from St Louis Bus Station to Los Angeles Union StationbusGreyhound US1210
    2. Take the bus from Los Angeles to San DiegobusAmtrak Thruway Connecting Service
    43h 50m
  4. Train (Amtrak)

    1. Take the train from St. Louis to Kansas Citytrain
    2. Take the train from Kansas City to Fullerton Amtrak Stationtrain
    3. Take the train from Fullerton Amtrak Station to San Diegotrain
    45h 1m
    $218–729
  5. Drive 1,797.9 mi

    1. Drive from UNION STATION station to Santa Fe Depotcar1,797.9 mi
    29h 3m
    $329–474

Lambert–St. Louis International Airport (STL) to San Diego International Airport (SAN) flights

Calendar60Weekly Planes
Duration5h 17mAverage Duration
Ticket$203Cheapest Price
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Questions & Answers

What companies run services between UNION STATION station, MO, USA and Santa Fe Depot, San Diego County, CA, USA?

Southwest Airlines, United Airlines, and American Airlines fly from Lambert–St. Louis International Airport (STL) to San Diego International Airport (SAN) every 3 hours. Alternatively, you can take a vehicle from UNION STATION station to San Diego via St Louis Bus Station, Los Angeles Union Station, and Los Angeles in around 43h 50m.

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