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How to get fromTwentyone Hotel, Rome to Milanby train, bus, car, subway, plane or train (Trenitalia)

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There are 6 ways to get from Twentyone Hotel, Rome to Milan by train, bus, car, subway, plane, or train (Trenitalia)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train via Lepanto

    best
    1. Take the train from Roma Termini to Milano Centraletrain train 9950 / ...
    3h 29m
    €76–152
  2. Bus

    cheapest
    1. Take the bus from Roma, Autostazione Tiburtina to Florence Villa Constanza Bus Stationbus bus 510 / ...
    2. Take the bus from Florence Villa Constanza Bus Station to Milano, San Donato M3bus bus N528 / ...
    8h 49m
    €38–77
  3. Drive 571.7 km

    1. Drive from Twentyone Hotel, Rome to Milancar car 571.7 km
    5h 18m
    €90–129
  4. Subway, fly

    1. Take the subway from Lepanto to Terminisubway subway
    2. Fly from Fiumicino International Airport (FCO) to Milan Linate Airport (LIN)plane plane FCO - LIN
    3h 18m
    €52–152
  5. Train

    1. Take the train from Roma Termini to Milano Centraletrain train Fr / ...
    4h 9m
    €72–167
  6. Train via Milan Rogoredo

    1. Take the train from Roma Termini to Milan Rogoredotrain train 9962
    4h 40m
    €72–152

Twentyone Hotel, Rome to Milan by foot and bus

Calendar62Weekly Services
Duration8h 49mAverage Duration
Ticket€38Cheapest Price
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Questions & Answers

What companies run services between Twentyone Hotel, Rome, Italy and Milan, Italy?

ItaloTreno operates a train from Roma Termini to Milano Centrale every 30 minutes. Tickets cost €75–150 and the journey takes 3h 5m. Alternatively, you can take a vehicle from Twentyone Hotel, Rome to Milano, San Donato M3 via P.Le Flaminio, Roma, Autostazione Tiburtina, and Florence Villa Constanza Bus Station in around 8h 49m.

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