There are 9 ways to get from Tuscaloosa to South Carolina by bus, plane, train or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Bus, fly to Greenville/Spartanburg  •  6 h 33 min

  1. Take the bus from Tuscaloosa, Al to Birmingham, Al
  2. Fly from Birmingham (BHM) to Greenville/Spartanburg (GSP) BHM - GSP

$224 - $1,073

Cheapest option

Bus  •  12 h 5 min

  1. Take the bus from Tuscaloosa, Al to Atlanta, Ga 1522 / ...
  2. Take the bus from Atlanta, Ga to Florence, SC Atlanta

$65 - $123

7 alternative options

Bus, fly to Columbia  •  6 h 21 min

  1. Take the bus from Tuscaloosa, Al to Birmingham, Al
  2. Fly from Birmingham (BHM) to Columbia (CAE) BHM - CAE

$248 - $1,258

Bus, fly to Charlotte  •  5 h 15 min

  1. Take the bus from Tuscaloosa, Al to Birmingham, Al
  2. Fly from Birmingham (BHM) to Charlotte (CLT) BHM - CLT

$239 - $968

Bus, fly to Charleston  •  7 h 16 min

  1. Take the bus from Tuscaloosa, Al to Birmingham, Al
  2. Fly from Birmingham (BHM) to Charleston (CHS) BHM - CHS

$236 - $1,231

Bus via Birmingham, Al  •  10 h 43 min

  1. Take the bus from Tuscaloosa, Al to Birmingham, Al
  2. Take the bus from Birmingham, Al to Atlanta, Ga
  3. Take the bus from Atlanta, GA to Florence, SC

$70 - $139

Bus via Columbia, SC  •  12 h 37 min

  1. Take the bus from Tuscaloosa, Al to Birmingham, Al
  2. Take the bus from Birmingham, AL to Atlanta, GA - W Peachtree St @ Civic Center MARTA Station
  3. Take the bus from Atlanta GA to Columbia, SC
  4. Take the bus from Columbia, SC to Florence, SC

$67 - $117

Train  •  20 h 40 min

  1. Take the train from Tuscaloosa Amtrak to Greensboro Galyon Transportation Center
  2. Take the train from Greensboro Galyon Transportation Center to Selma-Smithfield Amtrak
  3. Take the train from Selma-Smithfield Amtrak to Florence Amtrak

$144 - $375

Drive  •  8 h 11 min

  1. Drive from Tuscaloosa to Florence 495.7 miles

$45 - $70

Questions & Answers

The cheapest way to get from Tuscaloosa to South Carolina is to drive which costs $45 - $70 and takes 8 h 11 min.

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The quickest way to get from Tuscaloosa to South Carolina is to bus and fly which costs $230 - $1,000 and takes 5 h 15 min.

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No, there is no direct bus from Tuscaloosa to South Carolina. However, there are services departing from Tuscaloosa, Al and arriving at Florence, SC via Birmingham, Al, Peachtree St @ Alabama St and Atlanta, GA. The journey, including transfers, takes approximately 10 h 43 min.

More details

No, there is no direct train from Tuscaloosa to South Carolina. However, there are services departing from Tuscaloosa Amtrak and arriving at Florence Amtrak via Greensboro Galyon Transportation Center and Selma-Smithfield Amtrak. The journey, including transfers, takes approximately 20 h 40 min.

More details

The distance between Tuscaloosa and South Carolina is 415 miles. The road distance is 495.7 miles.

Get driving directions

The best way to get from Tuscaloosa to South Carolina without a car is to bus which takes 10 h 43 min and costs $70 - $140.

More details

It takes approximately 6 h 33 min to get from Tuscaloosa to South Carolina, including transfers.

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Tuscaloosa to South Carolina bus services, operated by Greyhound USA, depart from Tuscaloosa, Al station.

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Tuscaloosa to South Carolina train services, operated by Amtrak, depart from Tuscaloosa Amtrak station.

More details

The best way to get from Tuscaloosa to South Carolina is to bus which takes 10 h 43 min and costs $70 - $140. Alternatively, you can train, which costs $140 - $380 and takes 20 h 40 min.

Mode details

Map of how to get from Tuscaloosa to South Carolina.
Launch map view
  • Distance: 414.9 miles
  • Duration: 6 h 33 min

What companies run services between Tuscaloosa, AL, USA and South Carolina, USA?

You can take a bus from Tuscaloosa to Florence via Birmingham, Al, Atlanta, Ga, Peachtree St @ Alabama St, Peachtree St Sw @ Brotherton Transportation Mall, and Atlanta, GA in around 10 h 43 min. Alternatively, you can take a train from Tuscaloosa to Florence via Greensboro Galyon Transportation Center and Selma-Smithfield Amtrak in around 20 h 40 min.

Airlines
American Airlines
Website
aa.com
Flights from Birmingham to Greenville/Spartanburg via Charlotte
Ave. Duration
4 h 16 min
When
Every day
Estimated price
$200 - $1,100
Flights from Birmingham to Greenville/Spartanburg via Reagan Washington
Ave. Duration
5 h 30 min
When
Saturday
Estimated price
$260 - $1,200
Flights from Birmingham to Greenville/Spartanburg via Chicago O'Hare
Ave. Duration
6 h 25 min
When
Every day
Estimated price
$270 - $1,200
Flights from Birmingham to Greenville/Spartanburg via Dallas/Ft.Worth
Ave. Duration
6 h 28 min
When
Every day
Estimated price
$300 - $1,300
Flights from Birmingham to Columbia via Charlotte
Ave. Duration
3 h 54 min
When
Every day
Estimated price
$240 - $1,300
Flights from Birmingham to Columbia via Philadelphia
Ave. Duration
5 h 53 min
When
Every day
Estimated price
$340 - $1,500
Flights from Birmingham to Columbia via Dallas/Ft.Worth
Ave. Duration
6 h 39 min
When
Every day
Estimated price
$360 - $1,500
Flights from Birmingham to Columbia via Reagan Washington
Ave. Duration
6 h 45 min
When
Saturday and Sunday
Estimated price
$310 - $1,400
Flights from Birmingham to Charlotte
Ave. Duration
1 h 36 min
When
Every day
Estimated price
$170 - $900
Flights from Birmingham to Charleston via Charlotte
Ave. Duration
3 h 57 min
When
Every day
Estimated price
$250 - $1,300
Flights from Birmingham to Charleston via Reagan Washington
Ave. Duration
5 h 5 min
When
Saturday
Estimated price
$310 - $1,400
Flights from Birmingham to Charleston via Miami
Ave. Duration
4 h 55 min
When
Every day
Estimated price
$320 - $1,400
Delta
Website
delta.com
Flights from Birmingham to Greenville/Spartanburg via Atlanta
Ave. Duration
3 h 35 min
When
Every day
Estimated price
$180 - $1,000
Flights from Birmingham to Greenville/Spartanburg via New York La Guardia
Ave. Duration
5 h 57 min
When
Monday, Wednesday, Thursday, Friday and Sunday
Estimated price
$280 - $1,300
Flights from Birmingham to Greenville/Spartanburg via Detroit
Ave. Duration
6 h 9 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$250 - $1,200
Flights from Birmingham to Columbia via Atlanta
Ave. Duration
3 h 48 min
When
Every day
Estimated price
$210 - $1,200
Flights from Birmingham to Charlotte via Atlanta
Ave. Duration
3 h 39 min
When
Every day
Estimated price
$150 - $850
Flights from Birmingham to Charleston via Atlanta
Ave. Duration
3 h 33 min
When
Every day
Estimated price
$220 - $1,200
Flights from Birmingham to Charleston via Detroit
Ave. Duration
5 h 26 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$310 - $1,500
United Airlines
Website
united.com
Flights from Birmingham to Columbia via Chicago O'Hare
Ave. Duration
5 h 5 min
When
Every day
Estimated price
$340 - $1,500
Flights from Birmingham to Columbia via Houston
Ave. Duration
5 h 49 min
When
Every day
Estimated price
$360 - $1,600
Flights from Birmingham to Charleston via Houston
Ave. Duration
5 h 13 min
When
Every day
Estimated price
$360 - $1,600
Flights from Birmingham to Charleston via Chicago O'Hare
Ave. Duration
5 h 25 min
When
Every day
Estimated price
$350 - $1,600
Southwest Airlines
Website
southwest.com
Flights from Birmingham to Charleston via Baltimore
Ave. Duration
4 h 25 min
When
Sunday
Estimated price
$360 - $1,400
Flights from Birmingham to Charleston via Chicago Midway
Ave. Duration
4 h 53 min
When
Monday to Saturday
Estimated price
$380 - $1,500
Train operators
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Tuscaloosa Amtrak to Greensboro Galyon Transportation Center
Ave. Duration
13 h 53 min
Frequency
Once daily
Estimated price
$80 - $230
Website
amtrak.com
Coach Seat
$80 - $130
Flexi Coach Seat
$140 - $220
Business Coach Seat
$160 - $230
Room
$350 - $490
Train from Greensboro Galyon Transportation Center to Selma-Smithfield Amtrak
Ave. Duration
2 h 22 min
Frequency
Once daily
Estimated price
$30 - $70
Website
amtrak.com
Coach Seat
$30 - $45
Flexi Coach Seat
$55 - $80
Business Coach Seat
$45 - $70
Room
$160 - $230
Train from Selma-Smithfield Amtrak to Florence Amtrak
Ave. Duration
2 h 25 min
Frequency
Once daily
Estimated price
$30 - $75
Website
amtrak.com
Coach Seat
$30 - $50
Flexi Coach Seat
$55 - $85
Business Coach Seat
$50 - $75
Room
$170 - $240
Bus operators
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Tuscaloosa, Al to Birmingham, Al
Ave. Duration
1 h 5 min
Frequency
Hourly
Estimated price
$12 - $26
Website
greyhound.com
Economy
$12 - $17
Flexible
$21 - $26
Bus from Birmingham, Al to Atlanta, Ga
Ave. Duration
2 h 30 min
Frequency
Hourly
Estimated price
$20 - $50
Website
greyhound.com
Economy
$20 - $30
Flexible
$35 - $50
Bus from Tuscaloosa, Al to Atlanta, Ga
Ave. Duration
4 h 10 min
Frequency
Hourly
Estimated price
$25 - $60
Website
greyhound.com
Economy
$25 - $40
Flexible
$45 - $60
South Eastern Stages
Phone
+1 877.836.7607 / 404.591.2750
Email
info@sestages.com
Website
southeasternstages.com
Bus from Atlanta, GA to Florence, SC
Ave. Duration
5 h 30 min
Frequency
Once daily
Estimated price
$35 - $60
Schedules at
southeasternstages.com
Bus from Atlanta, Ga to Florence, SC
Ave. Duration
6 h 55 min
Frequency
3 times a day
Estimated price
$40 - $65
Schedules at
southeasternstages.com
Bus from Columbia, SC to Florence, SC
Ave. Duration
1 h 20 min
Frequency
Once daily
Estimated price
$19 - $30
Schedules at
southeasternstages.com
Megabus
Phone
877-462-6342
Website
us.megabus.com
Bus from Birmingham, AL to Atlanta, GA - W Peachtree St @ Civic Center MARTA Station
Ave. Duration
2 h 45 min
Frequency
Twice daily
Estimated price
$15 - $26
Book at
megabus.com
Bus from Atlanta GA to Columbia, SC
Ave. Duration
4 h 15 min
Frequency
Twice daily
Estimated price
$21 - $35
Book at
megabus.com

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More Questions & Answers

There is no direct flight from Birmingham Airport to Greenville/Spartanburg Airport. The quickest flight takes 3 h 7 min and has one stopover.

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Tuscaloosa to South Carolina bus services, operated by South Eastern Stages, arrive at Florence, SC station.

More details

South Carolina is 1 h ahead of Tuscaloosa. It is currently 4:09 PM in Tuscaloosa and 5:09 PM in South Carolina.

Tuscaloosa to South Carolina train services, operated by Amtrak, arrive at Florence Amtrak station.

More details

Yes, the driving distance between Tuscaloosa to South Carolina is 496 miles. It takes approximately 8 h 11 min to drive from Tuscaloosa to South Carolina.

Get driving directions

Delta and American Airlines offer flights from Birmingham Airport to Greenville/Spartanburg Airport.

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Book your Tuscaloosa to South Carolina train tickets online with Rome2rio.

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There are 16+ hotels available in South Carolina. Prices start at $52 USD per night.

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