There are 8 ways to get from Tuscaloosa to South Carolina by train, plane, bus, night bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Train to Birmingham, fly to Columbia  •  6 h 41 min

  1. Take the train from Tuscaloosa Amtrak to Birmingham Amtrak
  2. Fly from Birmingham (BHM) to Columbia (CAE) BHM - CAE

$261 - $1,280

Cheapest option

Bus  •  13 h 45 min

  1. Take the bus from Tuscaloosa, Al to Birmingham, Al
  2. Take the bus from Birmingham, Al to Atlanta, Ga
  3. Take the bus from Atlanta, GA to Florence

$75 - $144

6 alternative options

Train to Birmingham, fly to Greenville/Spartanburg  •  6 h 34 min

  1. Take the train from Tuscaloosa Amtrak to Birmingham Amtrak
  2. Fly from Birmingham (BHM) to Greenville/Spartanburg (GSP) BHM - GSP

$237 - $1,095

Train to Birmingham, fly to Charlotte  •  5 h 28 min

  1. Take the train from Tuscaloosa Amtrak to Birmingham Amtrak
  2. Fly from Birmingham (BHM) to Charlotte (CLT) BHM - CLT

$252 - $990

Train to Birmingham, fly to Charleston  •  7 h 27 min

  1. Take the train from Tuscaloosa Amtrak to Birmingham Amtrak
  2. Fly from Birmingham (BHM) to Charleston (CHS) BHM - CHS

$249 - $1,253

Bus, bus to Montgomery, fly to Charlotte  •  6 h 40 min

  1. Take the bus from Tuscaloosa, Al to Birmingham, Al
  2. Take the bus from Birmingham, Al to Montgomery, Al
  3. Fly from Montgomery (MGM) to Charlotte (CLT) MGM - CLT

$294 - $1,167

Bus, night bus, train  •  13 h 55 min

  1. Take the bus from Tuscaloosa, Al to Birmingham, Al
  2. Take the bus from Birmingham, Al to Atlanta, Ga
  3. Take the night bus from Atlanta, Ga to Savannah, Ga
  4. Take the train from Savannah Amtrak to Florence Amtrak

$103 - $248

Drive  •  8 h 11 min

  1. Drive from Tuscaloosa to Florence 495.7 miles

$45 - $70

Questions & Answers

The cheapest way to get from Tuscaloosa to South Carolina is to drive which costs $45 - $70 and takes 8 h 11 min.

More details

The quickest way to get from Tuscaloosa to South Carolina is to train and fly which takes 5 h 28 min and costs $250 - $1,000.

More details

The distance between Tuscaloosa and South Carolina is 664 km. The road distance is 793 km.

Get driving directions

It takes approximately 6 h 41 min to get from Tuscaloosa to South Carolina, including transfers.

More details

No, there is no direct bus from Tuscaloosa to South Carolina. However, there are services departing from Tuscaloosa, Al and arriving at Florence via Birmingham, Al, Peachtree St @ Alabama St and Atlanta, GA. The journey, including transfers, takes approximately 13 h 45 min.

More details

What companies run services between Tuscaloosa, AL, USA and South Carolina, USA?

You can take a bus from Tuscaloosa to Florence via Birmingham, Al, Atlanta, Ga, Peachtree St @ Alabama St, Peachtree St Sw @ Brotherton Transportation Mall, and Atlanta, GA in around 13 h 45 min.

Airlines
Delta
Website
delta.com
Flights from Birmingham to Columbia via Atlanta
Ave. Duration
3 h 48 min
When
Every day
Estimated price
$210 - $1,200
Flights from Birmingham to Columbia via New York La Guardia
Ave. Duration
5 h 41 min
When
Tuesday and Wednesday
Estimated price
$330 - $1,500
Flights from Birmingham to Greenville/Spartanburg via Atlanta
Ave. Duration
3 h 34 min
When
Every day
Estimated price
$180 - $1,000
Flights from Birmingham to Greenville/Spartanburg via Detroit
Ave. Duration
5 h 53 min
When
Every day
Estimated price
$250 - $1,200
Flights from Birmingham to Greenville/Spartanburg via New York La Guardia
Ave. Duration
6 h 9 min
When
Monday, Thursday, Friday and Sunday
Estimated price
$280 - $1,300
Flights from Birmingham to Charlotte via Atlanta
Ave. Duration
3 h 39 min
When
Every day
Estimated price
$150 - $850
Flights from Birmingham to Charleston via Atlanta
Ave. Duration
3 h 34 min
When
Every day
Estimated price
$220 - $1,200
Flights from Birmingham to Charleston via Detroit
Ave. Duration
5 h 26 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$310 - $1,500
Flights from Montgomery to Charlotte via Atlanta
Ave. Duration
3 h 45 min
When
Every day
Estimated price
$180 - $1,000
American Airlines
Website
aa.com
Flights from Birmingham to Columbia via Charlotte
Ave. Duration
3 h 49 min
When
Every day
Estimated price
$240 - $1,300
Flights from Birmingham to Columbia via Philadelphia
Ave. Duration
5 h 36 min
When
Every day
Estimated price
$340 - $1,500
Flights from Birmingham to Columbia via Dallas/Ft.Worth
Ave. Duration
6 h 5 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$360 - $1,500
Flights from Birmingham to Columbia via Reagan Washington
Ave. Duration
6 h 45 min
When
Saturday
Estimated price
$310 - $1,400
Flights from Birmingham to Greenville/Spartanburg via Charlotte
Ave. Duration
4 h 27 min
When
Every day
Estimated price
$200 - $1,100
Flights from Birmingham to Greenville/Spartanburg via Reagan Washington
Ave. Duration
5 h 25 min
When
Saturday
Estimated price
$260 - $1,200
Flights from Birmingham to Greenville/Spartanburg via Chicago O'Hare
Ave. Duration
6 h 20 min
When
Every day
Estimated price
$270 - $1,200
Flights from Birmingham to Greenville/Spartanburg via Dallas/Ft.Worth
Ave. Duration
6 h 22 min
When
Every day
Estimated price
$300 - $1,300
Flights from Birmingham to Charlotte
Ave. Duration
1 h 37 min
When
Every day
Estimated price
$170 - $900
Flights from Birmingham to Charleston via Charlotte
Ave. Duration
3 h 36 min
When
Every day
Estimated price
$250 - $1,300
Flights from Birmingham to Charleston via Reagan Washington
Ave. Duration
4 h 52 min
When
Saturday
Estimated price
$310 - $1,400
Flights from Birmingham to Charleston via Miami
Ave. Duration
4 h 54 min
When
Every day
Estimated price
$320 - $1,400
Flights from Birmingham to Charleston via Philadelphia
Ave. Duration
5 h 28 min
When
Every day
Estimated price
$340 - $1,400
Flights from Montgomery to Charlotte
Ave. Duration
1 h 39 min
When
Every day
Estimated price
$190 - $1,000
United Airlines
Website
united.com
Flights from Birmingham to Columbia via Chicago O'Hare
Ave. Duration
5 h 39 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$340 - $1,500
Flights from Birmingham to Columbia via Houston
Ave. Duration
5 h 39 min
When
Every day
Estimated price
$360 - $1,600
Flights from Birmingham to Greenville/Spartanburg via Houston
Ave. Duration
5 h 15 min
When
Every day
Estimated price
$300 - $1,300
Flights from Birmingham to Greenville/Spartanburg via Chicago O'Hare
Ave. Duration
5 h 28 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$280 - $1,300
Flights from Birmingham to Charleston via Houston
Ave. Duration
5 h 26 min
When
Monday to Saturday
Estimated price
$360 - $1,600
Flights from Birmingham to Charleston via Chicago O'Hare
Ave. Duration
5 h 40 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$350 - $1,600
Southwest Airlines
Website
southwest.com
Flights from Birmingham to Charleston via Baltimore
Ave. Duration
4 h 58 min
When
Every day
Estimated price
$360 - $1,400
Flights from Birmingham to Charleston via Chicago Midway
Ave. Duration
5 h 20 min
When
Saturday
Estimated price
$380 - $1,500
Train operators
Amtrak
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Tuscaloosa Amtrak to Birmingham Amtrak
Ave. Duration
1 h 31 min
Frequency
Once daily
Estimated price
$24 - $50
Website
amtrak.com
Coach Seat
$24 - $40
Flexi Coach Seat
$40 - $65
Business Coach Seat
$35 - $50
Room
$140 - $200
Train from Savannah Amtrak to Florence Amtrak
Ave. Duration
3 h 14 min
Frequency
3 times a day
Estimated price
$40 - $100
Website
amtrak.com
Coach Seat
$40 - $60
Flexi Coach Seat
$70 - $110
Business Coach Seat
$70 - $100
Room
$200 - $280
Bus operators
Greyhound USA
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Tuscaloosa, Al to Birmingham, Al
Ave. Duration
1 h 5 min
Frequency
Hourly
Estimated price
$12 - $26
Website
greyhound.com
Economy
$12 - $17
Flexible
$21 - $26
Bus from Birmingham, Al to Montgomery, Al
Ave. Duration
1 h 40 min
Frequency
Hourly
Estimated price
$15 - $35
Website
greyhound.com
Economy
$15 - $23
Flexible
$27 - $35
Bus from Birmingham, Al to Atlanta, Ga
Ave. Duration
2 h 30 min
Frequency
Hourly
Estimated price
$20 - $50
Website
greyhound.com
Economy
$20 - $30
Flexible
$35 - $50
Night bus from Atlanta, Ga to Savannah, Ga
Ave. Duration
4 h 20 min
Frequency
Hourly
Estimated price
$29 - $70
Website
greyhound.com
Economy
$29 - $45
Flexible
$50 - $70

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