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How to get fromTupelo to Indianaby bus (Greyhound, Flixbus), car, plane, bus (Greyhound), bus or train

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There are 8 ways to get from Tupelo to Indiana by bus (Greyhound, Flixbus), car, plane, bus (Greyhound), bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Tupelo to Memphis Bus Stationbus
    2. Take the bus from Memphis Bus Station to Nashville Bus Stationbus
    3. Take the bus from Nashville Bus Station to Indianapolisbus
    13h 19m
    $119–302

  2. Fly Tupelo Regional Airport to Indianapolis

    cheapest
    1. Fly from Tupelo Regional Airport (TUP) to Indianapolis (IND)planeTUP - IND
    8h 24m
    $78–391

  3. Drive 463.5 mi

    1. Drive from Tupelo to Indianapoliscar463.5 mi
    9h 40m
    $85–123

  4. Bus via St. Louis

    1. Take the bus from Tupelo to Memphis Bus Stationbus
    2. Take the bus from Memphis Bus Station to St Louis Bus Stationbus
    3. Take the bus from St Louis Bus Station to Indianapolis Union Stationbus
    13h 34m
    $119–252

  5. Bus #2

    1. Take the bus from Tupelo to Memphis Bus StationbusGreyhound US0610
    2. Take the bus from Tornado Bus Co - West Memphis to IndianapolisbusMemphis
    14h 51m
    $149–306

  6. Fly Tupelo Regional Airport to Nashville, bus

    1. Fly from Tupelo Regional Airport (TUP) to Nashville (BNA)planeTUP - BNA
    2. Take the bus from Nashville Bus Station to Evansville Bus Stationbus
    6h 18m
    $168–241

  7. Bus to Memphis, fly to Chicago Midway International Airport, train

    1. Take the bus from Tupelo to Memphis Bus Stationbus
    2. Fly from Memphis (MEM) to Chicago Midway International Airport (MDW)planeMEM - MDW
    3. Take the train from Van Buren St. to Gary Metro Centertrain
    7h 29m
    $134–577

  8. Bus to Memphis, fly to Chicago O'Hare International Airport, train

    1. Take the bus from Tupelo to Memphis Bus Stationbus
    2. Fly from Memphis (MEM) to Chicago O'Hare International Airport (ORD)planeMEM - ORD
    3. Take the train from Van Buren St. to Gary Metro Centertrain
    8h 3m
    $199–577

Tupelo Regional Airport (TUP) to Indianapolis (IND) flights

Calendar17Weekly Planes
Duration8h 48mAverage Duration
Ticket$63Cheapest Price
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Questions & Answers

What companies run services between Tupelo, MS, USA and Indiana, USA?

You can take a vehicle from Tupelo to Indianapolis via Tupelo, Memphis Bus Station, and Nashville Bus Station in around 13h 19m. Alternatively, Corporate Flight Management Inc, Southwest Airlines, and two other airlines fly from Tupelo Regional Airport (TUP) to Indianapolis (IND) twice daily.

Airlines
Train operators
Bus operators

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