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How to get fromTupelo to Indianaby plane, bus, bus (Greyhound, Flixbus, Amtrak), car, train, bus (Greyhound, Flixbus), or bus (Greyhound)

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There are 9 ways to get from Tupelo to Indiana by plane, bus, bus (Greyhound, Flixbus, Amtrak), car, train, bus (Greyhound, Flixbus), or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Tupelo Regional Airport to Nashville, bus

    best
    1. Fly from Tupelo Regional Airport (TUP) to Nashville (BNA)plane plane TUP - BNA
    2. Take the bus from Nashville Bus Station to Evansville Bus Stationbus bus
    5h 52m
    $96–229

  2. Drive  464.4 mi

    cheapest
    1. Drive from Tupelo to Indianapoliscar car 464.4 mi
    9h 33m
    $85–123

  3. Bus

    1. Take the bus from Tupelo to Memphis Bus Stationbus bus
    2. Take the bus from Memphis Bus Station to Nashville Bus Stationbus bus
    3. Take the bus from Nashville Bus Station to Indianapolis Union Stationbus bus
    13h 39m
    $102–150

  4. Fly Tupelo Regional Airport to Indianapolis

    1. Fly from Tupelo Regional Airport (TUP) to Indianapolis (IND)plane plane TUP - IND
    4h 59m
    $97–509

  5. Bus to Memphis, fly to Chicago Midway International Airport, train

    1. Take the bus from Tupelo to Memphis Bus Stationbus bus
    2. Fly from Memphis (MEM) to Chicago Midway International Airport (MDW)plane plane MEM - MDW
    3. Take the train from Van Buren St. to Gary Metro Centertrain train
    7h 28m
    $108–476

  6. Bus to Memphis, fly to Chicago O'Hare International Airport, train

    1. Take the bus from Tupelo to Memphis Bus Stationbus bus
    2. Fly from Memphis (MEM) to Chicago O'Hare International Airport (ORD)plane plane MEM - ORD
    3. Take the train from Van Buren St. to Gary Metro Centertrain train
    8h 4m
    $93–386

  7. Bus via St. Louis

    1. Take the bus from Tupelo to Memphis Bus Stationbus bus
    2. Take the bus from Memphis Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Indianapolis Union Stationbus bus
    13h 54m
    $107–180

  8. Bus via Indianapolis

    1. Take the bus from Tupelo to Memphis Bus Stationbus bus
    2. Take the bus from Memphis Bus Station to Nashville Bus Stationbus bus
    3. Take the bus from Nashville Bus Station to Indianapolisbus bus
    14h 39m
    $102–170

  9. Bus #2

    1. Take the bus from Tupelo to Memphis Bus Stationbus bus Greyhound US0610
    2. Take the bus from Tornado Bus Co - West Memphis to Indianapolisbus bus Memphis
    14h 47m
    $160–198

Tupelo Regional Airport (TUP) to Nashville (BNA) flights

Calendar7Weekly Planes
Duration1h 5mAverage Duration
Ticket$56Cheapest Price
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Comparing Your Travel Options

Map of how to get from Tupelo to Indiana.ExpandLaunch map view
  • Distance: 339.3 mi
  • Duration: 5h 52m

What companies run services between Tupelo, MS, USA and Indiana, USA?

You can take a vehicle from Tupelo to Indianapolis Union Station via Tupelo, Memphis Bus Station, and Nashville Bus Station in around 13h 39m. Alternatively, Corporate Flight Management Inc, Southwest Airlines, and two other airlines fly from Tupelo Regional Airport (TUP) to Indianapolis (IND) twice daily.

Airlines
Train operators
Bus operators

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