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How to get fromTupelo to Durhamby car, plane, bus (Greyhound, Flixbus), bus, or train

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There are 8 ways to get from Tupelo to Durham by car, plane, bus (Greyhound, Flixbus), bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Golden Triangle Regional Airport, fly

    best
    1. Drive from Tupelo to Golden Triangle Regional Airport (GTR)car car
    2. Fly from Golden Triangle Regional Airport (GTR) to Raleigh-Durham International Airport (RDU)plane plane GTR - RDU
    6h 10m
    $97–472

  2. Bus via Atlanta

    1. Take the bus from Tupelo to Atlanta Bus Stationbus bus Greyhound US0610
    2. Take the bus from Atlanta Downtown to Durhambus bus FlixBus N2470
    13h 48m
    $109–177

  3. Drive  655.3 mi

    1. Drive from Tupelo to Durhamcar car 655.3 mi
    11h 11m
    $120–173

  4. Drive to Birmingham–Shuttlesworth International Airport, fly

    1. Drive from Tupelo to Birmingham-Airport-BHMcar car
    2. Fly from Birmingham–Shuttlesworth International Airport (BHM) to Raleigh-Durham International Airport (RDU)plane plane BHM - RDU
    5h 26m
    $105–501

  5. Bus to Memphis, fly

    1. Take the bus from Tupelo to Memphis Bus Stationbus bus
    2. Fly from Memphis (MEM) to Raleigh-Durham International Airport (RDU)plane plane MEM - RDU
    7h 26m
    $133–646

  6. Fly from Tupelo Regional Airport

    1. Fly from Tupelo Regional Airport (TUP) to Raleigh-Durham International Airport (RDU)plane plane TUP - RDU
    5h 17m
    $101–473

  7. Bus

    1. Take the bus from Tupelo to Atlanta Bus Stationbus bus Greyhound US0610
    2. Take the bus from Atlanta Bus Station to Durhambus bus FlixBus N2471 / ...
    13h 54m
    $106–184

  8. Bus, train

    1. Take the bus from Tupelo to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Downtown to Charlotte Bus Stationbus bus
    3. Take the train from Charlotte Amtrak Station to Durham Amtrak Stationtrain train
    15h 10m
    $128–233

Golden Triangle Regional Airport (GTR) to Raleigh-Durham International Airport (RDU) flights

Calendar21Weekly Planes
Duration5h 4mAverage Duration
Ticket$80Cheapest Price
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Questions & Answers

Map of how to get from Tupelo to Durham.ExpandLaunch map view
  • Distance: 659.9 mi
  • Duration: 6h 10m

What companies run services between Tupelo, MS, USA and Durham, NC, USA?

You can take a vehicle from Tupelo to Durham via Tupelo, Atlanta Bus Station, Garnett Station, Civic Center Station, and Atlanta Downtown in around 13h 48m. Alternatively, Corporate Flight Management Inc, Southwest Airlines, and American Airlines fly from Tupelo Regional Airport (TUP) to Raleigh-Durham International Airport (RDU) twice daily.

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