There are 7 ways to get from Tupelo to Durham by car, plane, bus (Greyhound, Flixbus), bus, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Drive to Golden Triangle Regional Airport, fly
best- Drive from Tupelo to Golden Triangle Regional Airport (GTR)car
- Fly from Golden Triangle Regional Airport (GTR) to Raleigh-Durham International Airport (RDU)plane GTR - RDU
6h 22m$76–399Bus via Atlanta
- Take the bus from Tupelo to Atlanta Bus Stationbus Greyhound US0610
- Take the bus from Atlanta Downtown to Durhambus FlixBus N2470
13h 38m$104–192Drive 655.3 mi
- Drive from Tupelo to Durhamcar 655.3 mi
11h 11m$120–173Bus to Memphis, fly
- Take the bus from Tupelo to Memphis Bus Stationbus
- Fly from Memphis (MEM) to Raleigh-Durham International Airport (RDU)plane MEM - RDU
7h 36m$159–653Fly from Tupelo Regional Airport
- Fly from Tupelo Regional Airport (TUP) to Raleigh-Durham International Airport (RDU)plane TUP - RDU
5h 6m$115–620Bus
- Take the bus from Tupelo to Atlanta Bus Stationbus Greyhound US0610
- Take the bus from Atlanta Bus Station to Durhambus FlixBus N2471 / ...
13h 54m$101–234Bus, train
- Take the bus from Tupelo to Atlanta Bus Stationbus
- Take the bus from Atlanta Downtown to Charlotte Bus Stationbus
- Take the train from Charlotte Amtrak Station to Durham Amtrak Stationtrain
15h$127–253
Golden Triangle Regional Airport (GTR) to Raleigh-Durham International Airport (RDU) flights
Questions & Answers
The cheapest way to get from Tupelo to Durham is to bus via Atlanta which costs $100 - $200 and takes 13h 38m.
The fastest way to get from Tupelo to Durham is to fly which takes 5h 6m and costs $110 - $650.
The distance between Tupelo and Durham is 664 miles. The road distance is 659.2 miles.
The best way to get from Tupelo to Durham without a car is to bus via Atlanta which takes 13h 38m and costs $100 - $200.
It takes approximately 6h 22m to get from Tupelo to Durham, including transfers.
The best way to get from Tupelo to Durham is to bus via Atlanta which takes 13h 38m and costs $100 - $200. Alternatively, you can fly, which costs $110 - $650 and takes 5h 6m.
Durham is 1h ahead of Tupelo. It is currently 5:40 PM in Tupelo and 6:40 PM in Durham.
Yes, the driving distance between Tupelo to Durham is 659 miles. It takes approximately 11h 11m to drive from Tupelo to Durham.
There are 290+ hotels available in Durham.
What companies run services between Tupelo, MS, USA and Durham, NC, USA?
You can take a vehicle from Tupelo to Durham via Tupelo, Atlanta Bus Station, Garnett Station, Civic Center Station, and Atlanta Downtown in around 13h 38m. Alternatively, Corporate Flight Management Inc, Southwest Airlines, and American Airlines fly from Tupelo Regional Airport (TUP) to Raleigh-Durham International Airport (RDU) once daily.
- Website
- delta.com
Flights from Golden Triangle Regional Airport to Raleigh-Durham International Airport via Atlanta
- Ave. Duration
- 4h 9m
- When
- Every day
- Estimated price
- $65–380
Flights from Memphis to Raleigh-Durham International Airport via Atlanta
- Ave. Duration
- 4h 16m
- When
- Every day
- Estimated price
- $95–550
- Website
- aa.com
Flights from Golden Triangle Regional Airport to Raleigh-Durham International Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 6m
- When
- Every day
- Estimated price
- $120–600
Flights from Memphis to Raleigh-Durham International Airport via Charlotte
- Ave. Duration
- 4h 7m
- When
- Every day
- Estimated price
- $90–550
Flights from Tupelo Regional Airport to Raleigh-Durham International Airport via Nashville
- Ave. Duration
- 5h 5m
- When
- Sunday
- Estimated price
- $100–600
Flights from Tupelo Regional Airport to Raleigh-Durham International Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 31m
- When
- Monday, Wednesday, Thursday, and Friday
- Estimated price
- $190–950
- Website
- southwest.com
Flights from Memphis to Raleigh-Durham International Airport via Nashville
- Ave. Duration
- 3h 50m
- When
- Every day
- Estimated price
- $90–550
Flights from Memphis to Raleigh-Durham International Airport via Chicago Midway
- Ave. Duration
- 4h 37m
- When
- Every day
- Estimated price
- $130–700
Flights from Tupelo Regional Airport to Raleigh-Durham International Airport via Nashville
- Ave. Duration
- 3h 25m
- When
- Monday to Friday
- Estimated price
- $100–600
- Website
- flybreeze.com
Flights from Memphis to Raleigh-Durham International Airport
- Ave. Duration
- 2h 2m
- When
- Monday and Friday
- Estimated price
- $80–490
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Charlotte Amtrak Station to Durham Amtrak Station
- Ave. Duration
- 2h 35m
- Frequency
- 5 times a day
- Estimated price
- $35–85
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Tupelo to Atlanta Bus Station
- Ave. Duration
- 5h 30m
- Frequency
- Twice daily
- Estimated price
- $45–90
- Website
- https://www.greyhound.com/
Bus from Tupelo to Memphis Bus Station
- Ave. Duration
- 1h 50m
- Frequency
- Twice daily
- Estimated price
- $17–35
- Website
- https://www.greyhound.com/
Bus from Atlanta Bus Station to Durham
- Ave. Duration
- 8h 20m
- Frequency
- Once daily
- Estimated price
- $65–130
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Atlanta Downtown to Durham
- Ave. Duration
- 6h 55m
- Frequency
- 5 times a week
- Estimated price
- $45–85
- Schedules at
- flixbus.com
Bus from Atlanta Bus Station to Durham
- Ave. Duration
- 7h 20m
- Frequency
- 3 times a day
- Estimated price
- $45–85
- Schedules at
- flixbus.com
Bus from Atlanta Downtown to Charlotte Bus Station
- Ave. Duration
- 4h 10m
- Frequency
- 5 times a week
- Estimated price
- $29–55
- Schedules at
- flixbus.com
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