There are 11 ways to get from Tupelo to Detroit by car, plane, bus, train, bus (Greyhound, Flixbus), or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Drive to Huntsville International Airport-Carl T Jones Field, fly
best- Drive from Tupelo to Huntsville International Airport-Carl T Jones Field (HSV)car
- Fly from Huntsville International Airport-Carl T Jones Field (HSV) to Detroit (DTW)plane HSV - DTW
5h 39m$110–525Fly from Tupelo Regional Airport
cheapest- Fly from Tupelo Regional Airport (TUP) to Detroit (DTW)plane TUP - DTW
5h 14m$83–401Bus, train
- Take the bus from Tupelo to Memphis Bus Stationbus
- Take the bus from Memphis Bus Station to Chicago Bus Stationbus
- Take the train from Chicago Union Station to Dearborntrain
19h 12m$151–374Bus, train via St. Louis
- Take the bus from Tupelo to Memphis Bus Stationbus
- Take the bus from Memphis Bus Station to St Louis Bus Stationbus
- Take the train from St. Louis to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Detroittrain
20h 24m$159–572Drive 724.5 mi
- Drive from Tupelo to Detroitcar 724.5 mi
13h 19m$133–191Drive to Golden Triangle Regional Airport, fly
- Drive from Tupelo to Golden Triangle Regional Airport (GTR)car
- Fly from Golden Triangle Regional Airport (GTR) to Detroit (DTW)plane GTR - DTW
6h 55m$93–438Drive to Birmingham–Shuttlesworth International Airport, fly
- Drive from Tupelo to Birmingham-Airport-BHMcar
- Fly from Birmingham–Shuttlesworth International Airport (BHM) to Detroit (DTW)plane BHM - DTW
5h 48m$146–737Bus to Memphis, fly
- Take the bus from Tupelo to Memphis Bus Stationbus
- Fly from Memphis (MEM) to Detroit (DTW)plane MEM - DTW
7h 18m$192–465Bus
- Take the bus from Tupelo to Memphis Bus Stationbus
- Take the bus from Memphis Bus Station to Chicago Bus Stationbus
- Take the bus from Chicago Bus Station to Detroit Bus Stationbus
19h 29m$134–322Bus via Atlanta (Greyhound)
- Take the bus from Tupelo to Atlanta Bus Stationbus Greyhound US0610
- Take the bus from Atlanta Bus Station to Detroit Bus Stationbus Greyhound US0110 / ...
22h 24m$135–312Bus via Champaign
- Take the bus from Tupelo to Memphis Bus Stationbus
- Take the bus from Memphis Bus Station to Champaign Intermodal Trans Ctrbus
- Take the bus from Champaign Intermodal Trans Ctr to Chicagobus
- Take the bus from Chicago to Detroit Bus Stationbus
23h 14m$165–347
Huntsville International Airport-Carl T Jones Field (HSV) to Detroit (DTW) flights
Questions & Answers
The cheapest way to get from Tupelo to Detroit is to drive which costs $130 - $200 and takes 13h 19m.
The fastest way to get from Tupelo to Detroit is to fly which takes 5h 14m and costs $80 - $410.
The distance between Tupelo and Detroit is 707 miles. The road distance is 728.7 miles.
The best way to get from Tupelo to Detroit without a car is to bus and train which takes 19h 12m and costs $150 - $380.
It takes approximately 5h 39m to get from Tupelo to Detroit, including transfers.
The best way to get from Tupelo to Detroit is to fly which takes 5h 14m and costs $80 - $410. Alternatively, you can bus, which costs $130 - $330 and takes 19h 29m.
Detroit is 1h ahead of Tupelo. It is currently 2:51 PM in Tupelo and 3:51 PM in Detroit.
Yes, the driving distance between Tupelo to Detroit is 729 miles. It takes approximately 13h 19m to drive from Tupelo to Detroit.
There are 418+ hotels available in Detroit.
What companies run services between Tupelo, MS, USA and Detroit, MI, USA?
Corporate Flight Management Inc, Southwest Airlines, and American Airlines fly from Tupelo Regional Airport (TUP) to Detroit (DTW) twice daily. Alternatively, you can take a vehicle from Tupelo to Detroit Bus Station via Tupelo, Memphis Bus Station, and Chicago Bus Station in around 19h 29m.
- Website
- delta.com
Flights from Huntsville International Airport-Carl T Jones Field to Detroit
- Ave. Duration
- 1h 50m
- When
- Every day
- Estimated price
- $85–490
Flights from Huntsville International Airport-Carl T Jones Field to Detroit via Atlanta
- Ave. Duration
- 4h 17m
- When
- Every day
- Estimated price
- $100–550
Flights from Golden Triangle Regional Airport to Detroit via Atlanta
- Ave. Duration
- 5h 11m
- When
- Every day
- Estimated price
- $80–420
Flights from Golden Triangle Regional Airport to Detroit via Atlanta, Covington
- Ave. Duration
- 8h 18m
- When
- Every day
- Estimated price
- $80–420
Flights from Birmingham–Shuttlesworth International Airport to Detroit
- Ave. Duration
- 2h 6m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $120–700
Flights from Birmingham–Shuttlesworth International Airport to Detroit via Atlanta
- Ave. Duration
- 4h 26m
- When
- Every day
- Estimated price
- $130–750
Flights from Memphis to Detroit
- Ave. Duration
- 1h 57m
- When
- Every day
- Estimated price
- $90–550
Flights from Memphis to Detroit via Atlanta
- Ave. Duration
- 4h 27m
- When
- Every day
- Estimated price
- $110–600
- Website
- aa.com
Flights from Huntsville International Airport-Carl T Jones Field to Detroit via Charlotte
- Ave. Duration
- 4h 33m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $100–600
Flights from Golden Triangle Regional Airport to Detroit via Dallas/Ft.Worth
- Ave. Duration
- 5h 32m
- When
- Every day
- Estimated price
- $110–550
Flights from Birmingham–Shuttlesworth International Airport to Detroit via Charlotte
- Ave. Duration
- 4h 25m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $140–800
Flights from Birmingham–Shuttlesworth International Airport to Detroit via Chicago O'Hare
- Ave. Duration
- 4h 54m
- When
- Monday to Friday
- Estimated price
- $140–750
Flights from Memphis to Detroit via Charlotte
- Ave. Duration
- 4h 42m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $120–650
Flights from Memphis to Detroit via Chicago O'Hare
- Ave. Duration
- 4h 41m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $100–550
Flights from Tupelo Regional Airport to Detroit via Dallas/Ft.Worth
- Ave. Duration
- 6h 20m
- When
- Every day
- Estimated price
- $110–550
- Website
- southwest.com
Flights from Birmingham–Shuttlesworth International Airport to Detroit via Nashville
- Ave. Duration
- 3h 55m
- When
- Saturday
- Estimated price
- $120–700
Flights from Birmingham–Shuttlesworth International Airport to Detroit via Chicago Midway
- Ave. Duration
- 4h 15m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $140–750
Flights from Memphis to Detroit via Chicago Midway
- Ave. Duration
- 3h 45m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $95–550
Flights from Tupelo Regional Airport to Detroit via Nashville
- Ave. Duration
- 3h 45m
- When
- Monday, Thursday, Friday, and Saturday
- Estimated price
- $65–380
- Website
- united.com
Flights from Birmingham–Shuttlesworth International Airport to Detroit via Chicago O'Hare
- Ave. Duration
- 4h 41m
- When
- Every day
- Estimated price
- $140–750
Flights from Memphis to Detroit via Chicago O'Hare
- Ave. Duration
- 4h 41m
- When
- Every day
- Estimated price
- $100–550
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Chicago Union Station to Dearborn
- Ave. Duration
- 4h 47m
- Frequency
- 3 times a day
- Estimated price
- $45–140
- Website
- https://www.amtrak.com/home.html
Train from St. Louis to Chicago Union Station
- Ave. Duration
- 4h 55m
- Frequency
- 5 times a day
- Estimated price
- $40–280
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to Detroit
- Ave. Duration
- 5h 20m
- Frequency
- 3 times a day
- Estimated price
- $45–140
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Tupelo to Memphis Bus Station
- Ave. Duration
- 1h 50m
- Frequency
- Twice daily
- Estimated price
- $29–60
- Website
- https://www.greyhound.com/
Bus from Memphis Bus Station to Chicago Bus Station
- Ave. Duration
- 9h 30m
- Frequency
- Once daily
- Estimated price
- $65–160
- Website
- https://www.greyhound.com/
Bus from Memphis Bus Station to St Louis Bus Station
- Ave. Duration
- 5h 15m
- Frequency
- Once daily
- Estimated price
- $35–65
- Website
- https://www.greyhound.com/
Bus from Chicago Bus Station to Detroit Bus Station
- Ave. Duration
- 6h 5m
- Frequency
- 3 times a day
- Estimated price
- $30–75
- Website
- https://www.greyhound.com/
Bus from Tupelo to Atlanta Bus Station
- Ave. Duration
- 5h 30m
- Frequency
- Twice daily
- Estimated price
- $45–90
- Website
- https://www.greyhound.com/
Bus from Atlanta Bus Station to Detroit Bus Station
- Ave. Duration
- 15h 50m
- Frequency
- Twice daily
- Estimated price
- $80–210
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Memphis Bus Station to Chicago Bus Station
- Ave. Duration
- 11h 5m
- Frequency
- 5 times a week
- Estimated price
- $70–120
- Schedules at
- flixbus.com
Bus from Memphis Bus Station to St Louis Bus Station
- Ave. Duration
- 4h 45m
- Frequency
- 5 times a week
- Estimated price
- $40–80
- Schedules at
- flixbus.com
Bus from Chicago Bus Station to Detroit Bus Station
- Ave. Duration
- 7h 55m
- Frequency
- Twice daily
- Estimated price
- $35–90
- Schedules at
- flixbus.com
Bus from Memphis Bus Station to Champaign Intermodal Trans Ctr
- Ave. Duration
- 8h 30m
- Frequency
- 5 times a week
- Estimated price
- $55–100
- Schedules at
- flixbus.com
- Adult
- $55–100
Bus from Champaign Intermodal Trans Ctr to Chicago
- Ave. Duration
- 2h 20m
- Frequency
- Twice daily
- Estimated price
- $26–55
- Schedules at
- flixbus.com
Bus from Chicago to Detroit Bus Station
- Ave. Duration
- 7h 30m
- Frequency
- Once daily
- Estimated price
- $45–120
- Schedules at
- flixbus.com
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide






