There are 8 ways to get from Tupelo to Cleveland by car, plane, bus, train, bus (Greyhound, Flixbus), or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Drive to Golden Triangle Regional Airport, fly
best- Drive from Tupelo to Golden Triangle Regional Airport (GTR)car
- Fly from Golden Triangle Regional Airport (GTR) to Cleveland-Hopkins International Airport (CLE)plane GTR - CLE
6h 48m$114–568Fly from Tupelo Regional Airport
cheapest- Fly from Tupelo Regional Airport (TUP) to Cleveland-Hopkins International Airport (CLE)plane TUP - CLE
4h 25m$108–520Bus, train
- Take the bus from Tupelo to Memphis Bus Stationbus
- Take the bus from Memphis Bus Station to Chicago Bus Stationbus
- Take the train from Chicago Union Station to Cleveland Amtraktrain
19h 48m$294–481Bus, train via St. Louis
- Take the bus from Tupelo to Memphis Bus Stationbus
- Take the bus from Memphis Bus Station to St Louis Bus Stationbus
- Take the train from St. Louis to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Cleveland Amtraktrain
21h 9m$404–651Drive 714.5 mi
- Drive from Tupelo to Clevelandcar 714.5 mi
13h 7m$123–177Bus to Memphis, fly
- Take the bus from Tupelo to Memphis Bus Stationbus
- Fly from Memphis (MEM) to Cleveland-Hopkins International Airport (CLE)plane MEM - CLE
8h 5m$143–695Bus via Chicago
- Take the bus from Tupelo to Memphis Bus Stationbus
- Take the bus from Memphis Bus Station to Chicago Bus Stationbus
- Take the bus from Chicago to Clevelandbus
20h 29m$144–271Bus (Greyhound)
- Take the bus from Tupelo to Atlanta Bus Stationbus Greyhound US0610
- Take the bus from Atlanta Bus Station to Cleveland Bus Stationbus Greyhound US0105
25h 51m$204–312
Golden Triangle Regional Airport (GTR) to Cleveland-Hopkins International Airport (CLE) flights
Comparing Your Travel Options
The cheapest way to get from Tupelo to Cleveland is to drive which costs $120 - $180 and takes 13h 7m.
The fastest way to get from Tupelo to Cleveland is to fly which takes 4h 25m and costs $100 - $550.
No, there is no direct bus from Tupelo to Cleveland. However, there are services departing from Tupelo and arriving at Cleveland via Memphis Bus Station and Chicago. The journey, including transfers, takes approximately 20h 29m.
The distance between Tupelo and Cleveland is 740 miles. The road distance is 718.7 miles.
The best way to get from Tupelo to Cleveland without a car is to bus and train which takes 19h 48m and costs $290 - $490.
It takes approximately 6h 48m to get from Tupelo to Cleveland, including transfers.
Tupelo to Cleveland bus services, operated by Greyhound USA, depart from Tupelo station.
The best way to get from Tupelo to Cleveland is to fly which takes 4h 25m and costs $100 - $550. Alternatively, you can bus via Chicago, which costs $140 - $280 and takes 20h 29m.
Tupelo to Cleveland bus services, operated by Greyhound USA, arrive at Memphis Bus Station.
Cleveland is 1h ahead of Tupelo. It is currently 7:17 AM in Tupelo and 8:17 AM in Cleveland.
What companies run services between Tupelo, MS, USA and Cleveland, OH, USA?
Corporate Flight Management Inc, Southwest Airlines, and two other airlines fly from Tupelo Regional Airport (TUP) to Cleveland-Hopkins International Airport (CLE) twice daily. Alternatively, you can take a vehicle from Tupelo to Cleveland via Tupelo, Memphis Bus Station, and Chicago in around 20h 29m.
- Website
- delta.com
Flights from Golden Triangle Regional Airport to Cleveland-Hopkins International Airport via Atlanta
- Ave. Duration
- 5h 9m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $100–550
Flights from Tupelo Regional Airport to Cleveland-Hopkins International Airport via Nashville, Detroit
- Ave. Duration
- 6h 46m
- When
- Every day
- Estimated price
- $95–550
Flights from Memphis to Cleveland-Hopkins International Airport via Detroit
- Ave. Duration
- 4h 12m
- When
- Saturday and Sunday
- Estimated price
- $120–650
Flights from Memphis to Cleveland-Hopkins International Airport via Atlanta
- Ave. Duration
- 4h 12m
- When
- Every day
- Estimated price
- $140–750
- Website
- aa.com
Flights from Golden Triangle Regional Airport to Cleveland-Hopkins International Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 36m
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $160–750
Flights from Tupelo Regional Airport to Cleveland-Hopkins International Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 32m
- When
- Tuesday, Saturday, and Sunday
- Estimated price
- $150–750
Flights from Memphis to Cleveland-Hopkins International Airport via Charlotte
- Ave. Duration
- 4h 46m
- When
- Every day
- Estimated price
- $140–750
Flights from Memphis to Cleveland-Hopkins International Airport via Chicago O'Hare
- Ave. Duration
- 4h 40m
- When
- Every day
- Estimated price
- $130–700
- Website
- southwest.com
Flights from Tupelo Regional Airport to Cleveland-Hopkins International Airport via Nashville
- Ave. Duration
- 5h 7m
- When
- Every day
- Estimated price
- $90–500
Flights from Memphis to Cleveland-Hopkins International Airport via Nashville
- Ave. Duration
- 3h 25m
- When
- Every day
- Estimated price
- $110–650
Flights from Memphis to Cleveland-Hopkins International Airport via Chicago Midway
- Ave. Duration
- 4h 6m
- When
- Every day
- Estimated price
- $130–700
Flights from Memphis to Cleveland-Hopkins International Airport via Baltimore
- Ave. Duration
- 4h 55m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $160–800
- Website
- united.com
Flights from Memphis to Cleveland-Hopkins International Airport via Chicago O'Hare
- Ave. Duration
- 4h 43m
- When
- Every day
- Estimated price
- $130–700
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Chicago Union Station to Cleveland Amtrak
- Ave. Duration
- 6h 5m
- Frequency
- 3 times a day
- Estimated price
- $180–290
- Website
- Amtrak
Train from St. Louis to Chicago Union Station
- Ave. Duration
- 4h 55m
- Frequency
- 5 times a day
- Estimated price
- $150–240
- Website
- Amtrak
Train from Chicago Union Station to Cleveland Amtrak
- Ave. Duration
- 6h 5m
- Frequency
- 3 times a day
- Estimated price
- $180–290
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- Greyhound
Bus from Tupelo to Memphis Bus Station
- Ave. Duration
- 1h 50m
- Frequency
- 4 times a day
- Estimated price
- $18–27
- Website
- Greyhound
Bus from Memphis Bus Station to Chicago Bus Station
- Ave. Duration
- 9h 40m
- Frequency
- Twice daily
- Estimated price
- $95–150
- Website
- Greyhound
Bus from Tupelo to Memphis Bus Station
- Ave. Duration
- 1h 50m
- Frequency
- 4 times a day
- Estimated price
- $18–27
- Website
- Greyhound
Bus from Memphis Bus Station to St Louis Bus Station
- Ave. Duration
- 5h 15m
- Frequency
- Twice daily
- Estimated price
- $50–80
- Website
- Greyhound
Bus from Tupelo to Memphis Bus Station
- Ave. Duration
- 1h 50m
- Frequency
- 4 times a day
- Estimated price
- $18–27
- Website
- Greyhound
Bus from Tupelo to Memphis Bus Station
- Ave. Duration
- 1h 50m
- Frequency
- 4 times a day
- Estimated price
- $18–27
- Website
- Greyhound
Bus from Memphis Bus Station to Chicago Bus Station
- Ave. Duration
- 9h 40m
- Frequency
- Twice daily
- Estimated price
- $95–150
- Website
- Greyhound
Bus from Tupelo to Atlanta Bus Station
- Ave. Duration
- 5h 40m
- Frequency
- 4 times a day
- Estimated price
- $50–75
- Website
- Greyhound
Bus from Atlanta Bus Station to Cleveland Bus Station
- Ave. Duration
- 18h 25m
- Frequency
- Twice daily
- Estimated price
- $140–220
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Memphis Bus Station to Chicago Bus Station
- Ave. Duration
- 11h 5m
- Frequency
- Once daily
- Estimated price
- $85–130
- Schedules at
- Flixbus USA
Bus from Memphis Bus Station to St Louis Bus Station
- Ave. Duration
- 4h 45m
- Frequency
- Once daily
- Estimated price
- $45–70
- Schedules at
- Flixbus USA
Bus from Memphis Bus Station to Chicago Bus Station
- Ave. Duration
- 11h 5m
- Frequency
- Once daily
- Estimated price
- $85–130
- Schedules at
- Flixbus USA
- Phone
- +1 888-378-3823
- info@baronsbus.com
- Website
- Barons Bus
Bus from Chicago to Cleveland
- Ave. Duration
- 6h 55m
- Frequency
- Once daily
- Estimated price
- $30–80
- Website
- Barons Bus
Want to know more about travelling around United States
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Booking & Getting There
Yes, the driving distance between Tupelo to Cleveland is 719 miles. It takes approximately 13h 7m to drive from Tupelo to Cleveland.
Book your Tupelo to Cleveland bus tickets online with Omio.
There are 717+ hotels available in Cleveland.










