There are 7 ways to get from Tupelo to Boston by plane, bus, bus (Greyhound, Flixbus), train, car, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Tupelo Regional Airport to Manchester Airport, bus
best- Fly from Tupelo Regional Airport (TUP) to Manchester Airport (MHT)plane TUP - MHT
- Take the bus from Boston Manchester Airport to Bostonbus
9h 13m$119–502Fly Tupelo Regional Airport to Theodore Francis Green State Airport, train
cheapest- Fly from Tupelo Regional Airport (TUP) to Theodore Francis Green State Airport (PVD)plane TUP - PVD
- Take the train from TF Green Airport to South Stationtrain
10h 2m$94–383Bus
- Take the bus from Tupelo to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to New York Midtownbus
- Take the bus from New York Midtown to Bostonbus
28h 57m$231–364Bus, train
- Take the bus from Tupelo to Memphis Bus Stationbus
- Take the bus from Memphis Bus Station to St Louis Bus Stationbus
- Take the train from St. Louis to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Bostontrain
37h 6m$774–1,262Drive 1,255.8 mi
- Drive from Tupelo to Bostoncar 1,255.8 mi
22h 19m$215–310Bus to Hartsfield-Jackson Atlanta International Airport, fly to Theodore Francis Green State Airport, train
- Take the bus from Tupelo to Atlanta Bus Stationbus
- Fly from Hartsfield-Jackson Atlanta International Airport (ATL) to Theodore Francis Green State Airport (PVD)plane ATL - PVD
- Take the train from TF Green Airport to South Stationtrain
12h 4m$138–453Bus via New York
- Take the bus from Tupelo to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Port Authority Bus Terminalbus
- Take the bus from New York to Bostonbus
31h 52m$271–429
Tupelo Regional Airport (TUP) to Manchester Airport (MHT) flights
Comparing Your Travel Options
The cheapest way to get from Tupelo to Boston is to fly and train which costs $90 - $390 and takes 10h 2m.
The fastest way to get from Tupelo to Boston is to fly and bus which takes 9h 13m and costs $110 - $500.
No, there is no direct bus from Tupelo to Boston. However, there are services departing from Tupelo and arriving at Boston via Atlanta Bus Station and New York Midtown. The journey, including transfers, takes approximately 28h 57m.
The distance between Tupelo and Boston is 1170 miles. The road distance is 1263.2 miles.
The best way to get from Tupelo to Boston without a car is to bus which takes 28h 57m and costs $230 - $370.
It takes approximately 9h 13m to get from Tupelo to Boston, including transfers.
Tupelo to Boston bus services, operated by Greyhound USA, depart from Tupelo station.
Tupelo to Boston bus services, operated by Greyhound USA, arrive at Atlanta Bus Station.
Boston is 1h ahead of Tupelo. It is currently 6:33 AM in Tupelo and 7:33 AM in Boston.
Yes, the driving distance between Tupelo to Boston is 1263 miles. It takes approximately 22h 19m to drive from Tupelo to Boston.
What companies run services between Tupelo, MS, USA and Boston, MA, USA?
You can take a vehicle from Tupelo to Boston via Tupelo, Atlanta Bus Station, and New York Midtown in around 28h 57m.
- Website
- southwest.com
Flights from Tupelo Regional Airport to Manchester Airport via Nashville
- Ave. Duration
- 6h 35m
- When
- Monday, Thursday, and Friday
- Estimated price
- $95–470
Flights from Tupelo Regional Airport to Manchester Airport via Nashville, Baltimore
- Ave. Duration
- 8h 42m
- When
- Sunday, Tuesday, and Wednesday
- Estimated price
- $95–470
Flights from Tupelo Regional Airport to Theodore Francis Green State Airport via Nashville
- Ave. Duration
- 7h 45m
- When
- Monday to Friday
- Estimated price
- $70–350
Flights from Tupelo Regional Airport to Theodore Francis Green State Airport via Nashville, Baltimore
- Ave. Duration
- 11h 35m
- When
- Tuesday and Wednesday
- Estimated price
- $70–350
Flights from Hartsfield-Jackson Atlanta International Airport to Theodore Francis Green State Airport via Baltimore
- Ave. Duration
- 4h 32m
- When
- Every day
- Estimated price
- $65–340
- Website
- delta.com
Flights from Hartsfield-Jackson Atlanta International Airport to Theodore Francis Green State Airport
- Ave. Duration
- 2h 21m
- When
- Every day
- Estimated price
- $65–340
- Website
- flybreeze.com
Flights from Tupelo Regional Airport to Theodore Francis Green State Airport via Nashville, Richmond
- Ave. Duration
- 7h 13m
- When
- Sunday
- Estimated price
- $70–350
Flights from Tupelo Regional Airport to Theodore Francis Green State Airport via Nashville, Pittsburgh
- Ave. Duration
- 7h 17m
- When
- Sunday
- Estimated price
- $120–700
- Website
- aa.com
Flights from Tupelo Regional Airport to Manchester Airport via Nashville, Reagan Washington
- Ave. Duration
- 7h 42m
- When
- Monday to Saturday
- Estimated price
- $95–470
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from St. Louis to Chicago Union Station
- Ave. Duration
- 4h 55m
- Frequency
- 5 times a day
- Estimated price
- $150–240
- Website
- Amtrak
Train from Chicago Union Station to Boston
- Ave. Duration
- 22h 2m
- Frequency
- Once daily
- Estimated price
- $550–900
- Website
- Amtrak
Train from TF Green Airport to South Station
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- $9–16
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $9–16
Train from TF Green Airport to South Station
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- $9–16
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $9–16
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- Greyhound
Bus from Boston Manchester Airport to Boston
- Ave. Duration
- 1h 30m
- Frequency
- 4 times a day
- Estimated price
- $9–15
- Website
- Greyhound
Bus from Tupelo to Atlanta Bus Station
- Ave. Duration
- 5h 40m
- Frequency
- 4 times a day
- Estimated price
- $50–80
- Website
- Greyhound
Bus from Tupelo to Memphis Bus Station
- Ave. Duration
- 1h 50m
- Frequency
- 4 times a day
- Estimated price
- $18–28
- Website
- Greyhound
Bus from Memphis Bus Station to St Louis Bus Station
- Ave. Duration
- 5h 15m
- Frequency
- Twice daily
- Estimated price
- $50–80
- Website
- Greyhound
Bus from Tupelo to Atlanta Bus Station
- Ave. Duration
- 5h 40m
- Frequency
- 4 times a day
- Estimated price
- $50–80
- Website
- Greyhound
Bus from Tupelo to Atlanta Bus Station
- Ave. Duration
- 5h 40m
- Frequency
- 4 times a day
- Estimated price
- $50–80
- Website
- Greyhound
Bus from Atlanta Bus Station to Port Authority Bus Terminal
- Ave. Duration
- 19h 40m
- Frequency
- Every 4 hours
- Estimated price
- $170–260
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Atlanta Bus Station to New York Midtown
- Ave. Duration
- 17h 25m
- Frequency
- 5 times a day
- Estimated price
- $140–220
- Schedules at
- Flixbus USA
Bus from New York Midtown to Boston
- Ave. Duration
- 4h 20m
- Frequency
- Hourly
- Estimated price
- $30–50
- Schedules at
- Flixbus USA
Bus from Memphis Bus Station to St Louis Bus Station
- Ave. Duration
- 4h 45m
- Frequency
- Once daily
- Estimated price
- $45–70
- Schedules at
- Flixbus USA
- Phone
- 1-800-343-9999
- Website
- Peter Pan
Bus from New York to Boston
- Ave. Duration
- 4h 35m
- Frequency
- Hourly
- Estimated price
- $40–75
- Website
- Peter Pan
Want to know more about travelling around United States
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Booking & Getting There
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