From Toronto, ON - Pearson International Airport bus to Guelph, University, ON. 1 h 45 min $23. From UP Express Pearson Airport train to Toronto then train to Guelph. 2 h 10 min $67. From Pearson Airport Terminal 1 bus to Square One then bus to Guelph Central GO Bus. 2 h 19 min $17. From Toronto Airport (YYZ) taxi to Guelph. 54 min $174. From Toronto Airport (YYZ) drive to Guelph. 54 min $9.