There are 6 ways to get from Topeka to Sikeston by bus, taxi, train, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus, taxi
best- Take the bus from Topeka to St Louis Bus Station
- Take the bus from St Louis Bus Station to Cape Girardeau
- Take the taxi from Cape Girardeau to Sikeston
9h 54m$136–249Drive 438.5 mi
cheapest- Drive from Topeka to Sikeston438.5 mi
7h 18m$80–116Train, bus, taxi
- Take the train from Topeka Station to Kansas City
- Take the train from Kansas City to St. Louis
- Take the bus from St Louis Bus Station to Cape Girardeau
- Take the taxi from Cape Girardeau to Sikeston
12h 20m$150–232Bus to Kansas City, fly to Barkley Regional Airport, taxi
- Take the bus from Quincy Street Station - Topeka to 2745 Southwest Blvd - Kansas City
- Fly from Kansas City (MCI) to Barkley Regional Airport (PAH)MCI - PAH
- Take the taxi from Barkley Regional Airport (PAH) to Sikeston
10h 51m$303–1,004Drive to Manhattan Regional Airport, fly to Cape Girardeau Municipal Airport, taxi
- Drive from Topeka to Manhattan Regional Airport (MHK)
- Fly from Manhattan Regional Airport (MHK) to Cape Girardeau Municipal Airport (CGI)MHK - CGI
- Take the taxi from Cape Girardeau Municipal Airport (CGI) to Sikeston
7h 54m$182–652Bus to Kansas City, fly to Lambert–St. Louis International Airport, bus, taxi
- Take the bus from Quincy Street Station - Topeka to 2745 Southwest Blvd - Kansas City
- Fly from Kansas City (MCI) to Lambert–St. Louis International Airport (STL)MCI - STL
- Take the bus from St Louis Bus Station to Cape Girardeau
- Take the taxi from Cape Girardeau to Sikeston
9h 15m$318–875
Kansas City (MCI) to Barkley Regional Airport (PAH) flights
Questions & Answers
The cheapest way to get from Topeka to Sikeston is to drive which costs $80 - $120 and takes 7h 18m.
The fastest way to get from Topeka to Sikeston is to drive which takes 7h 18m and costs $80 - $120.
The distance between Topeka and Sikeston is 467 miles. The road distance is 441 miles.
The best way to get from Topeka to Sikeston without a car is to bus and taxi which takes 9h 54m and costs $130 - $250.
It takes approximately 9h 54m to get from Topeka to Sikeston, including transfers.
Yes, the driving distance between Topeka to Sikeston is 441 miles. It takes approximately 7h 18m to drive from Topeka to Sikeston.
There are 13+ hotels available in Sikeston.
What companies run services between Topeka, KS, USA and Sikeston, MO, USA?
There is no direct connection from Topeka to Sikeston. However, you can take the bus to St Louis Bus Station, take the bus to Cape Girardeau, then take the taxi to Sikeston. Alternatively, you can take the train to Kansas City, take the train to St. Louis, walk to St Louis Bus Station, take the bus to Cape Girardeau, then take the taxi to Sikeston.
- Website
- contouraviation.com
Flights from Kansas City to Barkley Regional Airport via Charlotte
- Ave. Duration
- 6h 24m
- When
- Every day
- Estimated price
- $200–1,000
Flights from Manhattan Regional Airport to Cape Girardeau Municipal Airport via Chicago O'Hare
- Ave. Duration
- 6h 16m
- When
- Every day
- Estimated price
- $100–550
Flights from Manhattan Regional Airport to Cape Girardeau Municipal Airport via Dallas/Ft.Worth
- Ave. Duration
- 8h 21m
- When
- Monday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- $230–950
Flights from Manhattan Regional Airport to Cape Girardeau Municipal Airport via Dallas/Ft.Worth, Chicago O'Hare
- Ave. Duration
- 7h 59m
- When
- Every day
- Estimated price
- $150–700
Flights from Manhattan Regional Airport to Cape Girardeau Municipal Airport via Chicago O'Hare, Dallas/Ft.Worth
- Ave. Duration
- 13h 26m
- When
- Monday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- $170–750
- Website
- southwest.com
Flights from Kansas City to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 6m
- When
- Every day
- Estimated price
- $90–650
- Website
- united.com
Flights from Kansas City to Barkley Regional Airport via Chicago O'Hare
- Ave. Duration
- 7h 9m
- When
- Every day
- Estimated price
- $140–800
Flights from Kansas City to Barkley Regional Airport via Houston
- Ave. Duration
- 7h 40m
- When
- Tuesday to Saturday
- Estimated price
- $200–1,000
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Topeka Station to Kansas City
- Ave. Duration
- 2h 1m
- Frequency
- Once daily
- Estimated price
- $22–50
- Website
- https://www.amtrak.com/home.html
Train from Kansas City to St. Louis
- Ave. Duration
- 5h 40m
- Frequency
- Twice daily
- Estimated price
- $35–65
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Topeka to St Louis Bus Station
- Ave. Duration
- 6h 15m
- Frequency
- Twice daily
- Estimated price
- $40–140
- Website
- https://www.greyhound.com/
Bus from St Louis Bus Station to Cape Girardeau
- Ave. Duration
- 2h 5m
- Frequency
- Once daily
- Estimated price
- $22–28
- Website
- https://www.greyhound.com/
- Phone
- +1 800-923-1799
- contactus@omexusa.net
- Website
- omnibusexpress.com
Bus from Quincy Street Station - Topeka to 2745 Southwest Blvd - Kansas City
- Ave. Duration
- 51 min
- Frequency
- Once daily
- Estimated price
- $40–55
- Schedules at
- omnibusexpress.com
- Ave. Duration
- 41 min
- Estimated price
- $70–150
Howard's Taxi Full Throttle
- Phone
- +1-573-270-9932
Howard's Taxi Full Throttle
- Phone
- +1-573-270-9932
Howard's Taxi Full Throttle
- Phone
- +1-573-270-9932
Howard's Taxi Full Throttle
- Phone
- +1-573-270-9932
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