There are 6 ways to get from Topeka to Mayo Clinic by bus, shuttle, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus, shuttle
best- Take the bus from Topeka to Kansas City Bus Stationbus
- Take the bus from Kansas City to Des Moinesbus
- Take the bus from Des Moines to Owatonnabus
- Take a shuttle bus from Owatonna, MN to Rochester
11h 40m$50–234Drive 461.1 mi
- Drive from Topeka to Mayo Cliniccar 461.1 mi
7h 37m$85–122Bus to Kansas City, fly to Rochester
- Take the bus from Quincy Street Station - Topeka to 2745 Southwest Blvd - Kansas Citybus
- Fly from Kansas City (MCI) to Rochester (RST)plane MCI - RST
9h 25m$114–534Bus
- Take the bus from Quincy Street Station - Topeka to 2745 Southwest Blvd - Kansas Citybus
- Take the bus from Kansas City to Des Moinesbus
- Take the bus from Des Moines to St. Paulbus
- Take the bus from St. Paul to Rochesterbus
13h 57m$91–309Bus to Kansas City, fly to Minneapolis–Saint Paul International Airport, bus
- Take the bus from Quincy Street Station - Topeka to 2745 Southwest Blvd - Kansas Citybus
- Fly from Kansas City (MCI) to Minneapolis–Saint Paul International Airport (MSP)plane MCI - MSP
- Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus
8h 21m$195–808Bus to Wichita Mid-Continent Airport, fly to Minneapolis–Saint Paul International Airport, bus
- Take the bus from Quincy Street Station - Topeka to 2210 Somerset St - Wichitabus
- Fly from Wichita Mid-Continent Airport (ICT) to Minneapolis–Saint Paul International Airport (MSP)plane ICT - MSP
- Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus
9h 22m$260–951
Topeka to Mayo Clinic by bus and foot
Questions & Answers
The cheapest way to get from Topeka to Mayo Clinic is to drive which costs $80 - $130 and takes 7h 37m.
The fastest way to get from Topeka to Mayo Clinic is to drive which takes 7h 37m and costs $80 - $130.
No, there is no direct bus from Topeka station to Mayo Clinic. However, there are services departing from Quincy Street Station - Topeka and arriving at Rochester via On Sw Blvd At 27Th Northbound Nearside, Kansas City, Des Moines and St. Paul. The journey, including transfers, takes approximately 13h 57m.
The distance between Topeka and Mayo Clinic is 488 miles. The road distance is 463.8 miles.
The best way to get from Topeka to Mayo Clinic without a car is to bus and shuttle which takes 11h 40m and costs $50 - $240.
It takes approximately 11h 40m to get from Topeka to Mayo Clinic, including transfers.
Topeka to Mayo Clinic bus services, operated by Omnibus Express, depart from Quincy Street Station - Topeka.
Topeka to Mayo Clinic bus services, operated by Omnibus Express, arrive at 2745 Southwest Blvd - Kansas City station.
Yes, the driving distance between Topeka to Mayo Clinic is 464 miles. It takes approximately 7h 37m to drive from Topeka to Mayo Clinic.
There are 85+ hotels available in Mayo Clinic.
What companies run services between Topeka, KS, USA and Mayo Clinic, MN, USA?
You can take a bus from Quincy Street Station - Topeka to Mayo Clinic via 2745 Southwest Blvd - Kansas City, On Sw Blvd At 27Th Northbound Nearside, On 12Th At Troost Eastbound, Kansas City, Des Moines, St. Paul, and Rochester in around 13h 57m.
- Website
- delta.com
Flights from Kansas City to Rochester via Minneapolis–Saint Paul International Airport
- Ave. Duration
- 4h 42m
- When
- Every day
- Estimated price
- $70–440
Flights from Kansas City to Minneapolis–Saint Paul International Airport
- Ave. Duration
- 1h 31m
- When
- Every day
- Estimated price
- $100–700
Flights from Wichita Mid-Continent Airport to Minneapolis–Saint Paul International Airport
- Ave. Duration
- 1h 56m
- When
- Every day
- Estimated price
- $130–800
- Website
- southwest.com
Flights from Kansas City to Minneapolis–Saint Paul International Airport via Chicago Midway
- Ave. Duration
- 3h 52m
- When
- Monday to Friday
- Estimated price
- $140–850
Flights from Wichita Mid-Continent Airport to Minneapolis–Saint Paul International Airport via Chicago Midway
- Ave. Duration
- 4h 27m
- When
- Monday, Thursday, and Friday
- Estimated price
- $180–950
Flights from Wichita Mid-Continent Airport to Minneapolis–Saint Paul International Airport via St. Louis
- Ave. Duration
- 4h 40m
- When
- Monday, Thursday, and Friday
- Estimated price
- $160–900
- Website
- aa.com
Flights from Kansas City to Rochester via Chicago O'Hare
- Ave. Duration
- 4h 14m
- When
- Monday to Saturday
- Estimated price
- $85–490
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Topeka to Kansas City Bus Station
- Ave. Duration
- 1h 10m
- Frequency
- 4 times a day
- Estimated price
- $10–19
- Website
- https://www.greyhound.com/
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Kansas City to Des Moines
- Ave. Duration
- 3h
- Frequency
- Twice daily
- Estimated price
- $18–90
- Book at
- https://www.jeffersonlines.com
Bus from Des Moines to Owatonna
- Ave. Duration
- 3h 30m
- Frequency
- Twice daily
- Estimated price
- $17–85
- Book at
- https://www.jeffersonlines.com
Bus from Des Moines to St. Paul
- Ave. Duration
- 4h 50m
- Frequency
- Once daily
- Estimated price
- $23–110
- Book at
- https://www.jeffersonlines.com
Bus from St. Paul to Rochester
- Ave. Duration
- 1h 25m
- Frequency
- Once daily
- Estimated price
- $7–55
- Book at
- https://www.jeffersonlines.com
- Phone
- +1 (888) 736-9190
- customerservice@landtoair.net
- Website
- landtoairexpress.com
Shuttle from Owatonna, MN to Rochester
- Ave. Duration
- 1h
- Frequency
- Twice daily
- Estimated price
- $5–40
- Schedules at
- landtoairexpress.com
- Adult
- $5–40
- Phone
- +1 800-923-1799
- contactus@omexusa.net
- Website
- omnibusexpress.com
Bus from Quincy Street Station - Topeka to 2745 Southwest Blvd - Kansas City
- Ave. Duration
- 51 min
- Frequency
- Once daily
- Estimated price
- $40–55
- Schedules at
- omnibusexpress.com
Bus from Quincy Street Station - Topeka to 2210 Somerset St - Wichita
- Ave. Duration
- 3h 20m
- Frequency
- Once daily
- Estimated price
- $50–65
- Schedules at
- omnibusexpress.com
- Phone
- + 1 507-280-9270
- Website
- groometransportation.com
Bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochester
- Ave. Duration
- 1h 30m
- Frequency
- Every 4 hours
- Estimated price
- $40–50
- Website
- https://groometransportation.com/minneapolis-st-paul-airport/rochester
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