Rome2Rio

How to get fromTopeka to Knoxvilleby car, plane, train, bus or bus (Greyhound)

Find Transport to Knoxville

See all options

There are 7 ways to get from Topeka to Knoxville by car, plane, train, bus, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Manhattan Regional Airport, fly

    best
    1. Drive from Topeka to Manhattan Regional Airport (MHK)car car
    2. Fly from Manhattan Regional Airport (MHK) to Mcghee Tyson Airport (TYS)plane plane MHK - TYS
    6h 9m
    $227–987

  2. Drive 790.5 mi

    cheapest
    1. Drive from Topeka to Knoxvillecar car 790.5 mi
    13h 10m
    $145–209

  3. Train, bus

    1. Take the train from Topeka Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the bus from New York to Knoxvillebus bus Nyc
    45h 2m
    $389–738

  4. Train, bus via Chicago

    1. Take the train from Topeka Station to Chicago Union Stationtrain train
    2. Take the bus from Chicago Bus Station to New York Midtownbus bus
    3. Take the bus from New York to Knoxvillebus bus Nyc
    45h 10m
    $364–608

  5. Bus to Kansas City, fly

    1. Take the bus from Quincy Street Station - Topeka to 2745 Southwest Blvd - Kansas Citybus bus
    2. Fly from Kansas City (MCI) to Mcghee Tyson Airport (TYS)plane plane MCI - TYS
    7h 40m
    $268–1,124

  6. Bus

    1. Take the bus from Topeka to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Port Authority Bus Terminalbus bus
    3. Take the bus from New York to Knoxvillebus bus Nyc
    45h 33m
    $306–502

  7. Train, bus via Ossining

    1. Take the train from Topeka Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Croton-Harmon Amtrak Stationtrain train
    3. Take the train from Croton-Harmon to Grand Central Terminaltrain train
    4. Take the bus from New York City to Knoxvillebus bus Ny
    45h 40m
    $350–621

Manhattan Regional Airport (MHK) to Mcghee Tyson Airport (TYS) flights

Calendar23Weekly Planes
Duration6h 26mAverage Duration
Ticket$169Cheapest Price
See schedules

Questions & Answers

What companies run services between Topeka, KS, USA and Knoxville, TN, USA?

You can take a bus from Topeka to Knoxville via St Louis Bus Station, Port Authority Bus Terminal, 42 St-Times Square, Canal St, New York, and Knoxville in around 45h 33m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Trips from Topeka

Trips to Knoxville

Popular routes