Spanish Railways (RENFE) operates a train from Toledo to Madrid Airport (MAD) every 10 minutes. Tickets cost $9 - $19 and the journey takes 33 min. EMT Madrid also services this route every 15 minutes. Alternatively, Alsa operates a bus from Toledo to Madrid Airport (MAD) hourly, and the journey takes 1 h. 2 other operators also service this route.
From Toledo train to Atocha Renfe then line 203 bus to Aeropuerto. 1 h 19 min £17. From Toledo bus to Plaza Eliptica, line 6 subway to Nuevos Ministerios, then line 8 subway to Aeropuerto T4. 1 h 57 min £3. From Toledo drive to Madrid Airport (MAD). 1 h £9.