Rome2Rio

How to get fromTimes Square to St. Louisby plane, bus (Greyhound), train (Amtrak), car, bus or train

Find Transport to St. Louis

See all options

There are 9 ways to get from Times Square to St. Louis by plane, bus (Greyhound), train (Amtrak), car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Laguardia Airport

    best
    1. Fly from Laguardia Airport (LGA) to Lambert–St. Louis International Airport (STL)plane plane LGA - STL
    5h 30m
    $278–613

  2. Fly from John F. Kennedy International Airport

    cheapest
    1. Fly from John F. Kennedy International Airport (JFK) to Lambert–St. Louis International Airport (STL)plane plane JFK - STL
    5h 9m
    $147–721

  3. Bus (Greyhound)

    1. Take the bus from Port Authority Bus Terminal to St Louis Bus Stationbus bus Greyhound US0421
    22h 50m
    $180–340

  4. Train (Amtrak)

    1. Take the train from Ny Moynihan Train Hall At Penn Station to Chicago Union Stationtrain train Lake Shore Limited / ...
    2. Take the train from Chicago Union Station to St. Louistrain train Lincoln Service / ...
    25h 18m
    $335–731

  5. Drive 944.8 mi

    1. Drive from Times Square to St. Louiscar car 944.8 mi
    16h 30m
    $173–250

  6. Bus to Newark Liberty International Airport, fly

    1. Take the bus from Port Authority Bus Terminal to Terminal Bbus bus
    2. Fly from Newark Liberty International Airport (EWR) to Lambert–St. Louis International Airport (STL)plane plane EWR - STL
    5h 19m
    $288–498

  7. Train to Philadelphia International Airport, fly

    1. Take the train from Ny Moynihan Train Hall At Penn Station to 30th Street Stationtrain train
    2. Fly from Philadelphia International Airport (PHL) to Lambert–St. Louis International Airport (STL)plane plane PHL - STL
    6h 21m
    $239–1,152

  8. Train to Long Island Mac Arthur Airport, fly

    1. Take the train from New York Penn Station to Central Isliptrain train
    2. Fly from Long Island Mac Arthur Airport (ISP) to Lambert–St. Louis International Airport (STL)plane plane ISP - STL
    8h 42m
    $318–1,633

  9. Train to Baltimore-Washington International Airport, fly

    1. Take the train from Ny Moynihan Train Hall At Penn Station to BWI Thurgood Marshalltrain train
    2. Fly from Baltimore-Washington International Airport (BWI) to Lambert–St. Louis International Airport (STL)plane plane BWI - STL
    7h 13m
    $316–577

Times Square to St. Louis by bus (Greyhound)

Calendar21Weekly Buses
Duration22h 50mAverage Duration
Ticket$180Cheapest Price
See schedules

Questions & Answers

What companies run services between Times Square, NY, USA and St. Louis, MO, USA?

American Airlines, Delta, and Southwest Airlines fly from Laguardia Airport (LGA) to Lambert–St. Louis International Airport (STL) hourly. Alternatively, Greyhound USA operates a bus from Port Authority Bus Terminal to St Louis Bus Station 3 times a day. Tickets cost $180–340 and the journey takes 22h 50m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers

Trips from Times Square

Trips to St. Louis

Popular routes