There are 8 ways to get from Tampa to Key Largo by bus, train, car, plane or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Bus  •  8 h 45 min

  1. Take the bus from Tampa to Miami, FL 3799 / ...
  2. Take the bus from Miami, FL - Airport Regency Hotel to Key Largo, FL 400

$26 - $89

7 alternative options

Train, bus  •  8 h 55 min

  1. Take the train from Tampa Amtrak to Hollywood Amtrak Silver Star
  2. Take the bus from Miami, FL - Airport Regency Hotel to Key Largo, FL 400

$65 - $135

Train, bus via Busway & W Palm Dr  •  9 h 11 min

  1. Take the train from Tampa Amtrak to Miami Amtrak Silver Star
  2. Take the bus from W Palm Dr & 3 Av to Mile Marker 98 Key Largo 301

$57 - $128

Drive  •  5 h 31 min

  1. Drive from Tampa to Key Largo 325.1 miles

$30 - $50

Line 30 bus to Tampa, fly to Miami  •  5 h 17 min

  1. Take the line 30 bus from Kennedy Blvd @ Ashley Dr to Airport Rental Car Facility
  2. Fly from Tampa (TPA) to Miami (MIA) TPA - MIA

$129 - $329

Line 30 bus to Tampa, fly to Fort Lauderdale  •  5 h 42 min

  1. Take the line 30 bus from Kennedy Blvd @ Ashley Dr to Airport Rental Car Facility
  2. Fly from Tampa (TPA) to Fort Lauderdale (FLL) TPA - FLL

$129 - $324

Bus to Orlando, fly to Miami  •  6 h 9 min

  1. Take the bus from Tampa, FL - McDonalds to Orlando, FL - McDonalds
  2. Fly from Orlando (MCO) to Miami (MIA) MCO - MIA

$189 - $459

Fly Tampa to West Palm Beach/Palm Beach, bus, shuttle  •  7 h 24 min

  1. Fly from Tampa (TPA) to West Palm Beach/Palm Beach (PBI) TPA - PBI
  2. Take the bus from West Palm Beach Airport to Miami Airport
  3. Take a shuttle bus from Miami, FL - International Airport to Key Largo, FL

$188 - $538

What companies run services between Tampa, FL, USA and Key Largo, FL, USA?

You can take a bus from Tampa to Key Largo via Miami, FL, Airport Station, Nw 42 Av & Nw 11 St, and Miami, FL - Airport Regency Hotel in around 8 h 45 min.

Airlines
American Airlines
Website
aa.com
Flights from Tampa to Miami
Ave. Duration
1 h 6 min
When
Every day
Estimated price
$65 - $360
Flights from Orlando to Miami
Ave. Duration
1 h 12 min
When
Every day
Estimated price
$85 - $600
Southwest Airlines
Website
southwest.com
Flights from Tampa to Fort Lauderdale
Ave. Duration
1 h
When
Every day
Estimated price
$90 - $360
Silver Airways
Website
silverairways.com
Flights from Tampa to Fort Lauderdale
Ave. Duration
1 h 17 min
When
Every day
Estimated price
$70 - $400
Flights from Tampa to West Palm Beach/Palm Beach
Ave. Duration
1 h 9 min
When
Every day
Estimated price
$70 - $430
Spirit Airlines
Website
spirit.com
Flights from Tampa to Fort Lauderdale
Ave. Duration
59 min
When
Every day
Estimated price
$55 - $250
Delta
Website
delta.com
Flights from Orlando to Miami
Ave. Duration
59 min
When
Every day
Estimated price
$60 - $480
Train operators
Amtrak
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Tampa Amtrak to Hollywood Amtrak
Ave. Duration
4 h 56 min
Frequency
Once daily
Estimated price
$45 - $120
Website
amtrak.com
Coach Seat
$45 - $70
Flexi Coach Seat
$80 - $120
Business Coach Seat
$80 - $120
Room
$210 - $300
Train from Tampa Amtrak to Miami Amtrak
Ave. Duration
5 h 21 min
Frequency
Once daily
Estimated price
$45 - $120
Website
amtrak.com
Coach Seat
$45 - $70
Flexi Coach Seat
$85 - $120
Business Coach Seat
$85 - $120
Room
$220 - $310
Bus operators
Greyhound USA
Phone
+1 214-849-8100
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Tampa, Fl to Miami, Fl
Ave. Duration
8 h 40 min
Frequency
Hourly
Estimated price
$30 - $75
Website
greyhound.com
Economy
$30 - $50
Flexible
$55 - $75
The Florida Express Bus
Phone
407-442-2810
Website
busticketreservations.com
Bus from Miami, FL - Airport Regency Hotel to Key Largo, FL
Ave. Duration
1 h 30 min
Frequency
Once daily
Estimated price
$13
Schedules at
thefloridaexpressbus.com
Book at
busticketreservations.com
Bus from Tampa, FL - McDonalds to Orlando, FL - McDonalds
Ave. Duration
1 h 15 min
Frequency
Twice daily
Estimated price
$16
Schedules at
busticketreservations.com
Book at
busticketreservations.com
Hillsborough Area Regional Transit
Website
gohart.org
Bus from Kennedy Blvd @ Ashley Dr to Airport Rental Car Facility
Ave. Duration
27 min
Frequency
Every 30 minutes
Estimated price
$2
Schedules at
gohart.org
Javax Bus
Phone
407-299-6360
Email
info@floridatransportation.net
Website
javaxbus.com
Bus from West Palm Beach Airport to Miami Airport
Ave. Duration
1 h 7 min
Frequency
Hourly
Estimated price
$49
Schedules at
javaxbus.com
Book at
gotobus.com
Keys Shuttle
Phone
+1 (888) 765-9997 | (305) 289-9997
Website
keysshuttle.com
Shuttle from Miami, FL - International Airport to Key Largo, FL
Ave. Duration
1 h 15 min
Frequency
5 times a day
Estimated price
$65 - $75
Schedules at
keysshuttle.com

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Questions & Answers

How far is it from Tampa to Key Largo?

The distance between Tampa and Key Largo is 376 km. The road distance is 520 km.

What is the cheapest way to get from Tampa to Key Largo?

The cheapest way to get from Tampa to Key Largo is to drive which costs $30 - $50 and takes 5 h 31 min.

What is the fastest way to get from Tampa to Key Largo?

The quickest way to get from Tampa to Key Largo is to line 30 bus and fly which takes 5 h 17 min and costs $120 - $330.

Is there a direct bus between Tampa and Key Largo?

No, there is no direct bus from Tampa to Key Largo. However, there are services departing from Tampa and arriving at Key Largo, FL via Airport Station and Miami, FL - Airport Regency Hotel. The journey, including transfers, takes approximately 8 h 45 min.

How long does it take to get from Tampa to Key Largo?

It takes approximately 8 h 45 min to get from Tampa to Key Largo, including transfers.