There are 9 ways to get from Tampa to Key Largo by bus, train, car, plane or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Bus  •  8h 38m

  1. Take the bus from Tampa, FL - Marion Transit Center to Miami Orlando
  2. Take the bus from Miami, FL - Airport Regency Hotel to Key Largo, FL 400

$56 - $102

Cheapest option

Train, bus via Homestead  •  9h 12m

  1. Take the train from Tampa Union Station to Miami Amtrak Station Silver Star
  2. Take the bus from W Palm Dr & 3 Av to Mile Marker 98 Key Largo 301

$50 - $66

7 alternative options

Train, bus  •  9h 5m

  1. Take the train from Tampa Union Station to Hollywood Amtrak Station Silver Star
  2. Take the bus from Miami, FL - Airport Regency Hotel to Key Largo, FL 400

$73 - $123

Bus via Tampa, Fl  •  11h 49m

  1. Take the bus from Tampa, Fl to Miami, Fl 3799 / ...
  2. Take the bus from Miami, FL - Airport Regency Hotel to Key Largo, FL 400

$68 - $114

Drive  •  5h 31m

  1. Drive from Tampa to Key Largo 325.1 miles

$30 - $50

Fly Tampa to Miami, shuttle  •  5h 1m

  1. Fly from Tampa (TPA) to Miami (MIA) TPA - MIA
  2. Take a shuttle bus from Miami, FL - International Airport to Key Largo, FL

$122 - $322

Fly Tampa to Fort Lauderdale, shuttle  •  5h 29m

  1. Fly from Tampa (TPA) to Fort Lauderdale (FLL) TPA - FLL
  2. Take a shuttle bus from Fort Lauderdale, FL - International Airport to Key Largo, FL

$122 - $322

Fly Tampa to Key West, bus  •  8h

  1. Fly from Tampa (TPA) to Key West (EYW) TPA - EYW
  2. Take the bus from Key West International Airport to Marathon - 29th Street
  3. Take the bus from Marathon, FL to Key Largo, FL

$131 - $496

Train to Orlando, fly to Miami, shuttle  •  7h 22m

  1. Take the train from Tampa Union Station to Kissimmee Amtrak Station
  2. Fly from Orlando (MCO) to Miami (MIA) MCO - MIA
  3. Take a shuttle bus from Miami, FL - International Airport to Key Largo, FL

$148 - $429

Questions & Answers

The cheapest way to get from Tampa to Key Largo is to drive which costs $30 - $50 and takes 5h 31m.

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The quickest way to get from Tampa to Key Largo is to fly and shuttle which costs $120 - $330 and takes 5h 1m.

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No, there is no direct bus from Tampa to Key Largo. However, there are services departing from Tampa, FL - Marion Transit Center and arriving at Key Largo, FL via Airport Station and Miami, FL - Airport Regency Hotel. The journey, including transfers, takes approximately 8h 38m.

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The distance between Tampa and Key Largo is 235 miles. The road distance is 325.1 miles.

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The best way to get from Tampa to Key Largo without a car is to bus which takes 8h 38m and costs $55 - $110.

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It takes approximately 8h 38m to get from Tampa to Key Largo, including transfers.

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Tampa to Key Largo bus services, operated by Megabus, depart from Tampa, FL - Marion Transit Center station.

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The quickest flight from Tampa Airport to Miami Airport is the direct flight which takes 1h 4m.

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Tampa to Key Largo bus services, operated by American Bus Tickets, arrive at Key Largo, FL station.

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Yes, the driving distance between Tampa to Key Largo is 325 miles. It takes approximately 5h 31m to drive from Tampa to Key Largo.

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Map of how to get from Tampa to Key Largo.
Launch map view
  • Distance: 234.9 miles
  • Duration: 8h 38m

What companies run services between Tampa, FL, USA and Key Largo, FL, USA?

You can take a bus from Tampa to Key Largo via Miami, Airport Station, Nw 42 Av & Nw 11 St, and Miami, FL - Airport Regency Hotel in around 8h 38m.

Airlines
American Airlines
Website
aa.com
Flights from Tampa to Miami
Ave. Duration
1h 7m
When
Every day
Estimated price
$65 - $360
Flights from Tampa to Key West via Miami
Ave. Duration
3h 19m
When
Every day
Estimated price
$250 - $1,100
Flights from Orlando to Miami
Ave. Duration
1h 10m
When
Every day
Estimated price
$85 - $600
Southwest Airlines
Website
southwest.com
Flights from Tampa to Fort Lauderdale
Ave. Duration
1h 9m
When
Every day
Estimated price
$90 - $360
Silver Airways
Website
silverairways.com
Flights from Tampa to Fort Lauderdale
Ave. Duration
1h 10m
When
Every day
Estimated price
$70 - $400
Flights from Tampa to Key West
Ave. Duration
1h 18m
When
Every day
Estimated price
$200 - $850
Flights from Tampa to Key West via Fort Lauderdale
Ave. Duration
3h 5m
When
Every day
Estimated price
$200 - $850
Spirit Airlines
Website
spirit.com
Flights from Tampa to Fort Lauderdale
Ave. Duration
1h 2m
When
Every day
Estimated price
$55 - $250
Train operators
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 215-856-7924
Website
amtrak.com
Train from Tampa Union Station to Hollywood Amtrak Station
Ave. Duration
4h 56m
Frequency
Once daily
Estimated price
$40 - $60
Website
amtrak.com
Coach Seat
$40 - $60
Premium
$210 - $290
Flexi Coach Seat
$65 - $100
Business Seat
$70 - $100
Train from Tampa Union Station to Miami Amtrak Station
Ave. Duration
5h 21m
Frequency
Once daily
Estimated price
$40 - $60
Website
amtrak.com
Coach Seat
$40 - $60
Premium
$210 - $300
Flexi Coach Seat
$70 - $110
Business Seat
$70 - $110
Train from Tampa Union Station to Kissimmee Amtrak Station
Ave. Duration
1h 21m
Frequency
Once daily
Estimated price
$26 - $40
Website
amtrak.com
Coach Seat
$26 - $40
Premium
$180 - $260
Flexi Coach Seat
$35 - $60
Business Seat
$35 - $55
Bus operators
Megabus
Phone
877-462-6342
Website
us.megabus.com
Bus from Tampa, FL - Marion Transit Center to Miami
Ave. Duration
5h 35m
Frequency
Twice daily
Estimated price
$26 - $40
Book at
megabus.com
American Bus Tickets
Phone
888-872-9992
Website
busticketreservations.com
Bus from Miami, FL - Airport Regency Hotel to Key Largo, FL
Ave. Duration
1h 30m
Frequency
Once daily
Estimated price
$27 - $60
More information at
American Bus Tickets
Bus from Marathon, FL to Key Largo, FL
Ave. Duration
1h 30m
Frequency
Once daily
Estimated price
$27 - $60
More information at
American Bus Tickets
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Tampa, Fl to Miami, Fl
Ave. Duration
8h 40m
Frequency
Every 4 hours
Estimated price
$35 - $55
Website
greyhound.com
Economy
$35 - $55
Flexible
$60 - $90
Keys Shuttle
Phone
+1 (888) 765-9997 | (305) 289-9997
Website
keysshuttle.com
Shuttle from Miami, FL - International Airport to Key Largo, FL
Ave. Duration
1h 15m
Frequency
Every 3 hours
Estimated price
$60 - $70
Schedules at
keysshuttle.com
Book at
keysshuttle.hudsonltd.net
Shuttle from Fort Lauderdale, FL - International Airport to Key Largo, FL
Ave. Duration
1h 45m
Frequency
Every 3 hours
Estimated price
$65 - $80
Schedules at
keysshuttle.com
Book at
keysshuttle.hudsonltd.net
Key West Transit
Phone
(305) 600-1455
Website
kwtransit.com
Bus from Key West International Airport to Marathon - 29th Street
Ave. Duration
1h 33m
Frequency
Every 3 hours
Estimated price
$2 - $4
Schedules at
kwtransit.com

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More Questions & Answers

American Airlines offers flights from Tampa Airport to Miami Airport.

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There are 76+ hotels available in Key Largo. Prices start at $100 USD per night.

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