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There are 9 ways to get from Tampa to Key Largo by bus, train, car, plane or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Bus Megabus  •  8 h 28 min

  1. Take the bus from Marion Transit Center Tampa to Miami
  2. Take the bus from Miami, FL - Airport Regency Hotel to Key Largo, FL 400

$55 - $102

8 alternative options

Train, bus  •  8 h 44 min

  1. Take the train from Tampa Union Station to Miami Amtrak Station Silver Star
  2. Take the bus from Miami, FL - Airport Regency Hotel to Key Largo, FL 400

$78 - $182

Train, bus via Busway & W Palm Dr  •  9 h 4 min

  1. Take the train from Tampa Union Station to Miami Amtrak Station Silver Star
  2. Take the bus from W Palm Dr & 3 Av to Mile Marker 98 Key Largo 301

$57 - $128

Bus Greyhound USA  •  11 h 49 min

  1. Take the bus from Tampa, Fl to Miami, Fl 3799 / ...
  2. Take the bus from Miami, FL - Airport Regency Hotel to Key Largo, FL 400

$65 - $147

Drive  •  5 h 31 min

  1. Drive from Tampa to Key Largo 325.1 miles

$30 - $50

Fly Tampa to Miami, shuttle  •  5 h 4 min

  1. Fly from Tampa (TPA) to Miami (MIA) TPA - MIA
  2. Take a shuttle bus from Miami, FL - International Airport to Key Largo, FL

$122 - $322

Fly Tampa to Fort Lauderdale, shuttle  •  5 h 23 min

  1. Fly from Tampa (TPA) to Fort Lauderdale (FLL) TPA - FLL
  2. Take a shuttle bus from Fort Lauderdale, FL - International Airport to Key Largo, FL

$122 - $322

Train to Orlando, fly to Miami, shuttle  •  7 h 23 min

  1. Take the train from Tampa Union Station to Kissimmee Amtrak Station
  2. Fly from Orlando (MCO) to Miami (MIA) MCO - MIA
  3. Take a shuttle bus from Miami, FL - International Airport to Key Largo, FL

$150 - $448

Fly Tampa to Key West, bus  •  8 h 5 min

  1. Fly from Tampa (TPA) to Key West (EYW) TPA - EYW
  2. Take the bus from Key West International Airport to Marathon, FL - Sombrero Beach Rd.
  3. Take the bus from Mile Marker 50 Marathon to Mile Marker 98 Key Largo

$107 - $439

Questions & Answers

The cheapest way to get from Tampa to Key Largo is to drive which costs $30 - $50 and takes 5 h 31 min.

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The quickest way to get from Tampa to Key Largo is to fly and shuttle which costs $120 - $330 and takes 5 h 4 min.

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No, there is no direct bus from Tampa to Key Largo. However, there are services departing from Marion Transit Center Tampa and arriving at Key Largo, FL via Airport Station and Miami, FL - Airport Regency Hotel. The journey, including transfers, takes approximately 8 h 28 min.

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The distance between Tampa and Key Largo is 235 miles. The road distance is 325.1 miles.

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The best way to get from Tampa to Key Largo without a car is to bus which takes 8 h 28 min and costs $55 - $110.

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It takes approximately 8 h 28 min to get from Tampa to Key Largo, including transfers.

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Tampa to Key Largo bus services, operated by Megabus, depart from Marion Transit Center Tampa station.

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The quickest flight from Tampa Airport to Miami Airport is the direct flight which takes 1 h 6 min.

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Tampa to Key Largo bus services, operated by The Florida Express Bus, arrive at Key Largo, FL station.

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Yes, the driving distance between Tampa to Key Largo is 325 miles. It takes approximately 5 h 31 min to drive from Tampa to Key Largo.

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Map of how to get from Tampa to Key Largo.
Launch map view
  • Distance: 234.9 miles
  • Duration: 8 h 28 min

What companies run services between Tampa, FL, USA and Key Largo, FL, USA?

You can take a bus from Tampa to Key Largo via Miami, Airport Station, Nw 42 Av & Nw 11 St, and Miami, FL - Airport Regency Hotel in around 8 h 28 min.

Airlines
Southwest Airlines
Website
southwest.com
Flights from Tampa to Fort Lauderdale
Ave. Duration
1 h 1 min
When
Every day
Estimated price
$90 - $360
American Airlines
Website
aa.com
Flights from Tampa to Miami
Ave. Duration
1 h 8 min
When
Every day
Estimated price
$65 - $360
Flights from Orlando to Miami
Ave. Duration
1 h 12 min
When
Every day
Estimated price
$85 - $600
Flights from Tampa to Key West via Miami
Ave. Duration
3 h 29 min
When
Every day
Estimated price
$250 - $1,100
Silver Airways
Website
silverairways.com
Flights from Tampa to Fort Lauderdale
Ave. Duration
1 h 20 min
When
Every day
Estimated price
$70 - $400
Flights from Tampa to Key West
Ave. Duration
1 h 25 min
When
Every day
Estimated price
$200 - $850
Spirit Airlines
Website
spirit.com
Flights from Tampa to Fort Lauderdale
Ave. Duration
1 h
When
Every day
Estimated price
$55 - $250
Train operators
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 215-856-7924
Website
amtrak.com
Train from Tampa Union Station to Miami Amtrak Station
Ave. Duration
5 h 21 min
Frequency
Once daily
Estimated price
$45 - $120
Website
amtrak.com
Coach Seat
$45 - $70
Flexi Coach Seat
$85 - $120
Business Coach Seat
$85 - $120
Room
$220 - $310
Train from Tampa Union Station to Kissimmee Amtrak Station
Ave. Duration
1 h 21 min
Frequency
Once daily
Estimated price
$27 - $55
Website
amtrak.com
Coach Seat
$27 - $40
Flexi Coach Seat
$45 - $70
Business Coach Seat
$35 - $55
Room
$150 - $210
Bus operators
The Florida Express Bus
Phone
407-442-2810
Website
busticketreservations.com
Bus from Miami, FL - Airport Regency Hotel to Key Largo, FL
Ave. Duration
1 h 30 min
Frequency
Once daily
Estimated price
$27 - $60
More information at
American Bus Tickets
Miami Dade Transit
Phone
+1 305-468-5900
Website
miamidade.gov
Bus from W Palm Dr & 3 Av to Mile Marker 98 Key Largo
Ave. Duration
55 min
Frequency
Hourly
Estimated price
$3
Schedules at
miamidade.gov
Bus from Mile Marker 50 Marathon to Mile Marker 98 Key Largo
Ave. Duration
1 h 15 min
Frequency
Every 3 hours
Estimated price
$3
Schedules at
miamidade.gov
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Tampa, Fl to Miami, Fl
Ave. Duration
8 h 40 min
Frequency
Every 4 hours
Estimated price
$35 - $85
Website
greyhound.com
Economy
$35 - $55
Flexible
$65 - $85
Keys Shuttle
Phone
+1 (888) 765-9997 | (305) 289-9997
Website
keysshuttle.com
Shuttle from Miami, FL - International Airport to Key Largo, FL
Ave. Duration
1 h 15 min
Frequency
5 times a day
Estimated price
$60 - $70
Schedules at
keysshuttle.com
Shuttle from Fort Lauderdale, FL - International Airport to Key Largo, FL
Ave. Duration
1 h 45 min
Frequency
5 times a day
Estimated price
$65 - $80
Schedules at
keysshuttle.com
Key West Transit
Phone
(305) 600-1455
Website
kwtransit.com
Bus from Key West International Airport to Marathon, FL - Sombrero Beach Rd.
Ave. Duration
1 h 42 min
Frequency
Every 4 hours
Estimated price
$2 - $4
Schedules at
cityofkeywest-fl.gov

Want to know more about travelling around United States

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More Questions & Answers

American Airlines offers flights from Tampa Airport to Miami Airport.

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There are 66+ hotels available in Key Largo. Prices start at $115 USD per night.

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