There are 9 ways to get from Tampa to Great Smoky Mountains National Park by plane, car, train, bus or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly Tampa to Knoxville, drive  •  6 h 54 min

  1. Fly from Tampa (TPA) to Knoxville (TYS) TPA - TYS
  2. Drive from Knoxville to Great Smoky Mountains National Park

$167 - $861

Cheapest option

Fly St. Petersburg to Knoxville, drive  •  6 h 4 min

  1. Fly from St. Petersburg (PIE) to Knoxville (TYS) PIE - TYS
  2. Drive from Knoxville to Great Smoky Mountains National Park

$103 - $327

7 alternative options

Fly Tampa to Asheville, drive  •  5 h 20 min

  1. Fly from Tampa (TPA) to Asheville (AVL) TPA - AVL
  2. Drive from Asheville to Great Smoky Mountains National Park

$299 - $864

Train to Orlando Sanford, fly to Knoxville, drive  •  7 h 8 min

  1. Take the train from Tampa Amtrak to Orlando Amtrak
  2. Fly from Orlando Sanford (SFB) to Knoxville (TYS) SFB - TYS
  3. Drive from Knoxville to Great Smoky Mountains National Park

$129 - $286

Fly St. Petersburg to Asheville, drive  •  6 h 9 min

  1. Fly from St. Petersburg (PIE) to Asheville (AVL) PIE - AVL
  2. Drive from Asheville to Great Smoky Mountains National Park

$105 - $330

Bus, Megabus, drive  •  14 h 37 min

  1. Take the bus from Tampa, FL to Atlanta, GA
  2. Take the Megabus from Atlanta GA to Knoxville
  3. Drive from Knoxville to Great Smoky Mountains National Park

$190 - $206

Bus, Megabus, taxi  •  18 h 15 min

  1. Take the bus from Tampa, Fl to Atlanta, Ga
  2. Take the Megabus from Atlanta GA to Knoxville
  3. Take a taxi from Mountain Grove SB before Majestic Grove to Great Smoky Mountains National Park

$290 - $430

Train, bus, drive  •  23 h 42 min

  1. Take the train from Tampa Amtrak to Cary Amtrak
  2. Take the train from Cary Amtrak to Greensboro Galyon Transportation Center Amtrak
  3. Take the bus from Greensboro, Nc to Winston Salem, Nc
  4. Take the bus from Winston Salem, Nc to Asheville, Nc
  5. Drive from Asheville, Nc to Great Smoky Mountains National Park

$164 - $419

Drive  •  9 h 41 min

  1. Drive from Tampa to Great Smoky Mountains National Park 639.9 miles

$60 - $95

Questions & Answers

The cheapest way to get from Tampa to Great Smoky Mountains National Park is to drive which costs $60 - $95 and takes 9 h 41 min.

More details

The quickest way to get from Tampa to Great Smoky Mountains National Park is to fly and drive which costs $290 - $900 and takes 5 h 20 min.

More details

The distance between Tampa and Great Smoky Mountains National Park is 535 miles. The road distance is 639.9 miles.

Get driving directions

It takes approximately 6 h 54 min to get from Tampa to Great Smoky Mountains National Park, including transfers.

More details

What companies run services between Tampa, FL, USA and Great Smoky Mountains National Park, TN, USA?

There is no direct connection from Tampa to Great Smoky Mountains National Park. However, you can take the bus to Airport Rental Car Facility, take the walk to SkyConnect Rental Car Facility Station, take the bus to SkyConnect Passenger Terminal Station, take the walk to Tampa airport, fly to Knoxville, then take the drive to Great Smoky Mountains National Park. Alternatively, you can take the bus to Airport Rental Car Facility, take the walk to SkyConnect Rental Car Facility Station, take the bus to SkyConnect Passenger Terminal Station, take the walk to Tampa airport, fly to Asheville, then take the drive to Great Smoky Mountains National Park.

Airlines
Delta
Website
delta.com
Flights from Tampa to Knoxville via Atlanta
Ave. Duration
4 h 5 min
When
Every day
Estimated price
$160 - $850
Flights from Tampa to Knoxville via Detroit
Ave. Duration
5 h 39 min
When
Every day
Estimated price
$230 - $1,100
Flights from Tampa to Asheville via Atlanta
Ave. Duration
3 h 44 min
When
Every day
Estimated price
$290 - $1,100
American Airlines
Website
aa.com
Flights from Tampa to Knoxville via Charlotte
Ave. Duration
4 h 12 min
When
Every day
Estimated price
$190 - $900
Flights from Tampa to Knoxville via Reagan Washington
Ave. Duration
4 h 43 min
When
Every day
Estimated price
$230 - $1,000
Flights from Tampa to Knoxville via Dallas/Ft.Worth
Ave. Duration
5 h 44 min
When
Every day
Estimated price
$270 - $1,100
Flights from Tampa to Knoxville via Philadelphia
Ave. Duration
5 h 44 min
When
Every day
Estimated price
$250 - $1,100
Flights from Tampa to Asheville via Charlotte
Ave. Duration
3 h 45 min
When
Every day
Estimated price
$300 - $1,200
Allegiant Air
Website
allegiantair.com
Flights from St. Petersburg to Knoxville
Ave. Duration
1 h 38 min
When
Every day
Estimated price
$90 - $310
Flights from Orlando Sanford to Knoxville
Ave. Duration
1 h 32 min
When
Every day
Estimated price
$110 - $380
Flights from St. Petersburg to Asheville
Ave. Duration
1 h 34 min
When
Every day
Estimated price
$90 - $310
United Airlines
Website
united.com
Flights from Tampa to Knoxville via Washington Dulles
Ave. Duration
5 h 22 min
When
Every day
Estimated price
$240 - $1,100
Flights from Tampa to Knoxville via Chicago O'Hare
Ave. Duration
5 h 23 min
When
Every day
Estimated price
$250 - $1,100
Spirit Airlines
Website
spirit.com
Flights from Tampa to Asheville
Ave. Duration
1 h 42 min
When
Thursday and Sunday
Estimated price
$90 - $420
Train operators
Amtrak
Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Tampa Amtrak to Orlando Amtrak
Ave. Duration
1 h 49 min
Frequency
Once daily
Estimated price
$29 - $65
Website
amtrak.com
Coach Seat
$29 - $45
Flexi Coach Seat
$50 - $75
Business Coach Seat
$40 - $65
Room
$150 - $220
Train from Tampa Amtrak to Cary Amtrak
Ave. Duration
14 h 41 min
Frequency
Once daily
Estimated price
$100 - $290
Website
amtrak.com
Coach Seat
$100 - $150
Flexi Coach Seat
$180 - $260
Business Coach Seat
$200 - $290
Room
$410 - $600
Train from Cary Amtrak to Greensboro Galyon Transportation Center Amtrak
Ave. Duration
1 h 19 min
Frequency
4 times a day
Estimated price
$26 - $55
Website
amtrak.com
Coach Seat
$26 - $40
Flexi Coach Seat
$45 - $70
Business Coach Seat
$35 - $55
Room
$140 - $210
Bus operators
La Cubana
Phone
+1 305-541-1700
Website
lacubanabus.com
Bus from Tampa, FL to Atlanta, GA
Ave. Duration
7 h 15 min
Frequency
3 times a week
Estimated price
$159
Schedules at
lacubanabus.com
Greyhound USA
Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Tampa, Fl to Atlanta, Ga
Ave. Duration
10 h 50 min
Frequency
Every 3 hours
Estimated price
$50 - $130
Website
greyhound.com
Economy
$50 - $85
Flexible
$100 - $130
Bus from Greensboro, Nc to Winston Salem, Nc
Ave. Duration
45 min
Frequency
Hourly
Estimated price
$9 - $20
Website
greyhound.com
Economy
$9 - $14
Flexible
$16 - $20
Bus from Winston Salem, Nc to Asheville, Nc
Ave. Duration
2 h 55 min
Frequency
Every 2 hours
Estimated price
$20 - $50
Website
greyhound.com
Economy
$20 - $30
Flexible
$35 - $50
Other operators
Taxi from Mountain Grove SB before Majestic Grove to Great Smoky Mountains National Park
Ave. Duration
1 h 26 min
Estimated price
$210 - $260
Knoxville Taxi Service
Phone
+1 865 691 1900
Website
knoxvilletaxicab.com

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Trips to Great Smoky Mountains National Park