There are 7 ways to get from Tampa to Great Smoky Mountains National Park by plane, car, train or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly Tampa to Knoxville, drive  •  6 h 56 min

  1. Fly from Tampa (TPA) to Knoxville (TYS) TPA - TYS
  2. Drive from Knoxville to Great Smoky Mountains National Park

$167 - $861

Cheapest option

Fly St. Petersburg to Knoxville, drive  •  6 h 19 min

  1. Fly from St. Petersburg (PIE) to Knoxville (TYS) PIE - TYS
  2. Drive from Knoxville to Great Smoky Mountains National Park

$97 - $321

5 alternative options

Fly Tampa to Asheville, drive  •  5 h 31 min

  1. Fly from Tampa (TPA) to Asheville (AVL) TPA - AVL
  2. Drive from Asheville to Great Smoky Mountains National Park

$299 - $864

Fly St. Petersburg to Asheville, drive  •  6 h 17 min

  1. Fly from St. Petersburg (PIE) to Asheville (AVL) PIE - AVL
  2. Drive from Asheville to Great Smoky Mountains National Park

$99 - $324

Train, train to Orlando Sanford, fly to Knoxville, drive  •  7 h 47 min

  1. Take the train from Tampa Amtrak to Kissimmee Amtrak
  2. Take the train from Kissimmee to Sanford
  3. Fly from Orlando Sanford (SFB) to Knoxville (TYS) SFB - TYS
  4. Drive from Knoxville to Great Smoky Mountains National Park

$130 - $284

Bus, drive  •  13 h 23 min

  1. Take the bus from Tampa, FL to Greenville, SC
  2. Drive from Greenville, SC to ART Station
  3. Drive from Pisgah View Rd at Canterbury Apartments to Great Smoky Mountains National Park

$172 - $180

Drive  •  9 h 40 min

  1. Drive from Tampa to Great Smoky Mountains National Park 639.9 miles

$60 - $95

Questions & Answers

The distance between Tampa and Great Smoky Mountains National Park is 535 miles. The road distance is 639.9 miles.

Get driving directions

It takes approximately 6 h 56 min to get from Tampa to Great Smoky Mountains National Park, including transfers.

More details

There is no direct flight from Tampa Airport to Knoxville Airport. The quickest flight takes 3 h 16 min and has one stopover.

Search flights

Yes, the driving distance between Tampa to Great Smoky Mountains National Park is 640 miles. It takes approximately 9 h 40 min to drive from Tampa to Great Smoky Mountains National Park.

Get driving directions

United Airlines, American Airlines and Delta offer flights from Tampa Airport to Knoxville Airport.

Search flights

There are 1719+ hotels available in Great Smoky Mountains National Park. Prices start at $67 USD per night.

More details

Map of how to get from Tampa to Great Smoky Mountains National Park.
Launch map view
  • Distance: 535.5 miles
  • Duration: 6 h 56 min

What companies run services between Tampa, FL, USA and Great Smoky Mountains National Park, TN, USA?

There is no direct connection from Tampa to Great Smoky Mountains National Park. However, you can take the bus to Airport Rental Car Facility, take the walk to SkyConnect Rental Car Facility Station, take the bus to SkyConnect Passenger Terminal Station, take the walk to Tampa airport, fly to Knoxville, then take the drive to Great Smoky Mountains National Park. Alternatively, you can take the bus to Airport Rental Car Facility, take the walk to SkyConnect Rental Car Facility Station, take the bus to SkyConnect Passenger Terminal Station, take the walk to Tampa airport, fly to Asheville, then take the drive to Great Smoky Mountains National Park.

Airlines
Delta
Website
delta.com
Flights from Tampa to Knoxville via Atlanta
Ave. Duration
3 h 41 min
When
Every day
Estimated price
$160 - $850
Flights from Tampa to Knoxville via Detroit
Ave. Duration
5 h 27 min
When
Saturday
Estimated price
$230 - $1,100
Flights from Tampa to Asheville via Atlanta
Ave. Duration
3 h 56 min
When
Every day
Estimated price
$290 - $1,100
American Airlines
Website
aa.com
Flights from Tampa to Knoxville via Charlotte
Ave. Duration
3 h 47 min
When
Every day
Estimated price
$190 - $900
Flights from Tampa to Knoxville via Reagan Washington
Ave. Duration
5 h 7 min
When
Every day
Estimated price
$230 - $1,000
Flights from Tampa to Knoxville via Chicago O'Hare
Ave. Duration
5 h 27 min
When
Every day
Estimated price
$250 - $1,100
Flights from Tampa to Knoxville via Philadelphia
Ave. Duration
5 h 34 min
When
Every day
Estimated price
$250 - $1,100
Flights from Tampa to Asheville via Charlotte
Ave. Duration
3 h 55 min
When
Every day
Estimated price
$300 - $1,200
Allegiant Air
Website
allegiantair.com
Flights from St. Petersburg to Knoxville
Ave. Duration
1 h 45 min
When
Every day
Estimated price
$90 - $310
Flights from St. Petersburg to Asheville
Ave. Duration
1 h 34 min
When
Every day
Estimated price
$90 - $310
Flights from Orlando Sanford to Knoxville
Ave. Duration
1 h 34 min
When
Every day
Estimated price
$110 - $380
United Airlines
Website
united.com
Flights from Tampa to Knoxville via Washington Dulles
Ave. Duration
5 h
When
Every day
Estimated price
$240 - $1,100
Flights from Tampa to Knoxville via Chicago O'Hare
Ave. Duration
5 h 31 min
When
Every day
Estimated price
$250 - $1,100
Spirit Airlines
Website
spirit.com
Flights from Tampa to Asheville
Ave. Duration
1 h 42 min
When
Thursday and Sunday
Estimated price
$90 - $420
Train operators
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Tampa Amtrak to Kissimmee Amtrak
Ave. Duration
1 h 21 min
Frequency
Once daily
Estimated price
$27 - $55
Website
amtrak.com
Coach Seat
$27 - $40
Flexi Coach Seat
$45 - $70
Business Coach Seat
$35 - $55
Room
$150 - $210
SunRail
Website
sunrail.com
Train from Kissimmee to Sanford
Ave. Duration
1 h 12 min
Frequency
Hourly
Estimated price
$3 - $5
Schedules at
sunrail.com
Bus operators
La Cubana
Phone
+1 305-541-1700
Website
lacubanabus.com
Bus from Tampa, FL to Greenville, SC
Ave. Duration
9 h 15 min
Frequency
3 times a week
Estimated price
$159
Schedules at
lacubanabus.com

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Trips to Great Smoky Mountains National Park