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There are 3 ways to get from Tampa to Cayo Guillermo by plane, car, train or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly Tampa to Santa Clara, drive

  1. Fly from Tampa (TPA) to Santa Clara (SNU)
  2. Drive from Santa Clara to Cayo Guillermo

Cheapest option

Train, train to Miami, fly to Santa Clara, drive

  1. Take the train from Tampa to Delray Beach Amtrak
  2. Take the train from Delray Beach Station to Miami Airport Station
  3. Fly from Miami (MIA) to Santa Clara (SNU)
  4. Drive from Santa Clara to Cayo Guillermo

1 alternative option

Fly Tampa to Camaguey, train, taxi

  1. Fly from Tampa (TPA) to Camaguey (CMW)
  2. Take the train from Camaguey to Ciego de Ávila
  3. Take a taxi from Morón to Cayo Guillermo

Coronavirus (COVID-19) in Cuba

There is widespread community transmission globally.
Some travel restrictions are being lifted in Cuba. For the latest travel status, please check the official page for Cuba.

For travel planning advice, please refer to our Rome2rio Coronavirus information page .

Coronavirus (COVID-19) Travel Advice

Some border closures are in place for Cuba due to Coronavirus (COVID-19). Most travel to this country is restricted.

Some domestic travel restrictions began to ease in Cuba from July 3.

Currently, we are unable to provide travel restriction information for leaving United States. For the latest Coronavirus (COVID-19) travel status in United States, please check government recommendations.

Last updated: January 29 | Data sourced from: ACAPS, OXFORD

Questions & Answers

The cheapest way to get from Tampa to Cayo Guillermo is to train and fly and drive which costs $210 - $450 and takes 13h 21m.

More details

The quickest way to get from Tampa to Cayo Guillermo is to fly and drive which costs $240 - $850 and takes 10h 3m.

More details

It is approximately 707 km to get from Tampa to Cayo Guillermo.

It takes approximately 10h 3m to get from Tampa to Cayo Guillermo, including transfers.

More details

There is no direct flight from Tampa Airport to Santa Clara Airport. The quickest flight takes 3h 26m and has one stopover.

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American Airlines offers flights from Tampa Airport to Santa Clara Airport.

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Map of how to get from Tampa to Cayo Guillermo.
Launch map view
  • Distance: 706.8 km
  • Duration: 10h 3m

What companies run services between Tampa, FL, USA and Cayo Guillermo, Cuba?

There is no direct connection from Tampa to Cayo Guillermo. However, you can take the line 30 bus to Airport Rental Car Facility, take the walk to SkyConnect Rental Car Facility Station, take the tram to SkyConnect Passenger Terminal Station, take the walk to Tampa airport, fly to Santa Clara, then take the drive to Cayo Guillermo. Alternatively, you can take the line 30 bus to Airport Rental Car Facility, take the walk to SkyConnect Rental Car Facility Station, take the tram to SkyConnect Passenger Terminal Station, take the walk to Tampa airport, fly to Camaguey, take the walk to Albaiza, take the bus to Amalia, take the bus to Los Coquitos, take the walk to Camaguey, take the train to Ciego de Ávila, take the walk to Ciego de Ávila, take the bus to Morón, then take the taxi to Cayo Guillermo.

Airlines
American Airlines
Website
aa.com
Flights from Tampa to Santa Clara via Miami
Ave. Duration
3h 26m
When
Monday, Tuesday, Friday, Saturday and Sunday
Estimated price
$210 - $800
Flights from Tampa to Santa Clara via Charlotte, Miami
Ave. Duration
6h 56m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$270 - $1,000
Flights from Tampa to Camaguey via Miami
Ave. Duration
3h 40m
When
Every day
Estimated price
$320 - $1,200
Flights from Miami to Santa Clara
Ave. Duration
1h 10m
When
Every day
Estimated price
$160 - $390
Cubana de Aviación
Website
cubana.cu
Flights from Tampa to Camaguey via Havana
Ave. Duration
5h 25m
When
Saturday
Estimated price
$200 - $850
Train operators
Ferrocarriles de Cuba
Website
en.wikipedia.org
Train from Camaguey to Ciego de Ávila
Ave. Duration
2h 12m
Frequency
Hourly
Estimated price
$1
Schedules at
thebusschedule.com
Old trains
$1
Second class
$1
First class
$1
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 800-872-7245
Website
amtrak.com
Train from Tampa to Delray Beach Amtrak
Ave. Duration
4h 10m
Frequency
Twice daily
Estimated price
$35 - $55
Website
Amtrak
Coach Seat
$35 - $55
Premium
$200 - $290
Flexi Coach Seat
$60 - $95
Business Seat
$60 - $90
Tri Rail
Phone
954-783-6030
Website
tri-rail.com
Train from Delray Beach Station to Miami Airport Station
Ave. Duration
1h 27m
Frequency
Hourly
Estimated price
$5 - $8
Website
tri-rail.com
Weekend | Holiday
$5
Weekday
$6 - $8
Other operators
Taxi from Morón to Cayo Guillermo
Ave. Duration
1h 22m
Estimated price
$65 - $80

Want to know more about travelling around Cuba

Rome2rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.