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There are 5 ways to get from Tampa Airport (TPA) to South Carolina by plane, bus, train or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly to Greenville/Spartanburg  •  2 h 2 min

  1. Fly from Tampa (TPA) to Greenville/Spartanburg (GSP) TPA - GSP

$113 - $448

Cheapest option

Bus  •  15 h 29 min

  1. Take the bus from Tampa, Fl to Florence, Sc 1008

$52 - $142

3 alternative options

Fly to Charlotte, bus  •  4 h 26 min

  1. Fly from Tampa (TPA) to Charlotte (CLT) TPA - CLT
  2. Take the bus from Transit Center- Bay X to White Street Park and Ride

$152 - $358

Train  •  14 h 11 min

  1. Take the train from Tampa Union Station to Kissimmee Amtrak Station Silver Star
  2. Take the train from Kissimmee Amtrak Station to Florence Amtrak Station Silver Meteor

$104 - $267

Drive  •  8 h 39 min

  1. Drive from Tampa Airport (TPA) to Florence 515.5 miles

$50 - $75

Questions & Answers

The cheapest way to get from Tampa Airport (TPA) to South Carolina is to drive which costs $50 - $75 and takes 8 h 39 min.

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The quickest way to get from Tampa Airport (TPA) to South Carolina is to fly which costs $110 - $450 and takes 2 h 2 min.

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No, there is no direct bus from Tampa Airport (TPA) to South Carolina. However, there are services departing from TPA Internat'l Airport Post Office and arriving at Florence, Sc via Tampa, Fl. The journey, including transfers, takes approximately 15 h 29 min.

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The distance between Tampa Airport (TPA) and South Carolina is 416 miles. The road distance is 515.5 miles.

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The best way to get from Tampa Airport (TPA) to South Carolina without a car is to train which takes 14 h 11 min and costs $100 - $270.

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It takes approximately 2 h 2 min to get from Tampa Airport (TPA) to South Carolina, including transfers.

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Tampa Airport (TPA) to South Carolina bus services, operated by Greyhound USA, depart from Tampa, Fl station.

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The best way to get from Tampa Airport (TPA) to South Carolina is to fly which takes 2 h 2 min and costs $110 - $450. Alternatively, you can train, which costs $100 - $270 and takes 14 h 11 min, you could also bus, which costs $50 - $150 and takes 15 h 29 min.

Mode details

The quickest flight from Tampa Airport to Greenville/Spartanburg Airport is the direct flight which takes 1 h 45 min.

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Tampa Airport (TPA) to South Carolina bus services, operated by Greyhound USA, arrive at Florence, Sc station.

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Map of how to get from Tampa Airport (TPA) to South Carolina.
Launch map view
  • Distance: 416.1 miles
  • Duration: 2 h 2 min

What companies run services between Tampa Airport (TPA), USA and South Carolina, USA?

Frontier Airlines, Southwest Airlines and two other airlines fly from Tampa Airport (TPA) to Greenville hourly. Alternatively, you can take a train from Tampa Airport (TPA) to Florence via Florida Ave @ Polk St, Tampa Union Station, and Kissimmee Amtrak Station in around 14 h 11 min.

Airlines
American Airlines
Website
aa.com
Flights from Tampa to Greenville/Spartanburg via Charlotte
Ave. Duration
3 h 31 min
When
Every day
Estimated price
$160 - $800
Flights from Tampa to Charlotte
Ave. Duration
1 h 44 min
When
Every day
Estimated price
$300 - $750
Southwest Airlines
Website
southwest.com
Flights from Tampa to Greenville/Spartanburg via Atlanta
Ave. Duration
3 h 20 min
When
Wednesday, Saturday and Sunday
Estimated price
$170 - $750
Flights from Tampa to Charlotte via Nashville
Ave. Duration
4 h
When
Wednesday
Estimated price
$340 - $750
Delta
Website
delta.com
Flights from Tampa to Greenville/Spartanburg via Atlanta
Ave. Duration
3 h 35 min
When
Every day
Estimated price
$140 - $800
Flights from Tampa to Charlotte via Atlanta
Ave. Duration
3 h 59 min
When
Every day
Estimated price
$300 - $700
Frontier Airlines
Website
flyfrontier.com
Flights from Tampa to Greenville/Spartanburg
Ave. Duration
1 h 45 min
When
Monday and Friday
Estimated price
$80 - $410
Flights from Tampa to Charlotte
Ave. Duration
1 h 50 min
When
Tuesday, Thursday and Sunday
Estimated price
$70 - $350
Train operators
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 215-856-7924
Website
amtrak.com
Train from Tampa Union Station to Kissimmee Amtrak Station
Ave. Duration
1 h 21 min
Frequency
Once daily
Estimated price
$27 - $55
Website
amtrak.com
Coach Seat
$27 - $40
Flexi Coach Seat
$45 - $70
Business Coach Seat
$35 - $55
Room
$150 - $210
Train from Kissimmee Amtrak Station to Florence Amtrak Station
Ave. Duration
10 h 6 min
Frequency
Once daily
Estimated price
$75 - $210
Website
amtrak.com
Coach Seat
$75 - $120
Flexi Coach Seat
$130 - $200
Business Coach Seat
$150 - $210
Room
$320 - $450
Bus operators
Charlotte Area Transit System
Phone
+1 704-336-7433
Email
telltransit@charlottenc.gov
Website
charlottenc.gov
Bus from Transit Center- Bay X to White Street Park and Ride
Ave. Duration
1 h 12 min
Frequency
3 times a day
Estimated price
$3 - $5
Schedules at
charlottenc.gov
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Tampa, Fl to Florence, Sc
Ave. Duration
13 h 55 min
Frequency
3 times a day
Estimated price
$50 - $140
Website
greyhound.com
Economy
$50 - $90
Flexible
$100 - $140

Want to know more about travelling around United States

Rome2rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

More Questions & Answers

Yes, the driving distance between Tampa Airport (TPA) to South Carolina is 516 miles. It takes approximately 8 h 39 min to drive from Tampa Airport (TPA) to South Carolina.

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Frontier Airlines, Delta, Southwest Airlines and American Airlines offer flights from Tampa Airport to Greenville/Spartanburg Airport.

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There are 17+ hotels available in South Carolina. Prices start at $49 USD per night.

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