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There are 10 ways to get from Syracuse to South Carolina by plane, bus, night bus, train or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly to Greenville/Spartanburg  •  5 h 59 min

  1. Fly from Syracuse (SYR) to Greenville/Spartanburg (GSP) SYR - GSP

$228 - $1,006

Cheapest option

Thru-Bus, bus  •  19 h 15 min

  1. Take the Thru-Bus from Syracuse, NY to New York, NY - 625 8th Ave P.A. Terminal Toronto
  2. Take the bus from New York, NY to Florence, SC Nyc / ...

$95 - $139

8 alternative options

Fly to Florence  •  5 h 47 min

  1. Fly from Syracuse (SYR) to Florence (FLO) SYR - FLO

$276 - $1,222

Fly to Charleston  •  6 h 32 min

  1. Fly from Syracuse (SYR) to Charleston (CHS) SYR - CHS

$230 - $1,114

Fly to Columbia  •  6 h 45 min

  1. Fly from Syracuse (SYR) to Columbia (CAE) SYR - CAE

$228 - $1,111

Fly to Charlotte, bus  •  6 h 27 min

  1. Fly from Syracuse (SYR) to Charlotte (CLT) SYR - CLT
  2. Take the bus from Transit Center- Bay X to White Street Park and Ride

$144 - $479

Night bus, train  •  16 h 52 min

  1. Take the night bus from Syracuse, Ny to Newark, Nj 311
  2. Take the train from Newark Penn Station to Florence Amtrak Station Palmetto / ...

$119 - $317

Train  •  18 h 55 min

  1. Take the train from Syracuse Regional Transportation Center to Albany-Rensselaer Amtrak Station
  2. Take the train from Albany-Rensselaer Amtrak Station to New York Penn Station
  3. Take the train from New York Penn Station to Florence Amtrak Station

$166 - $426

Bus  •  22 h 25 min

  1. Take the bus from Syracuse, Ny to New York, Ny 207 / ...
  2. Take the bus from New York, Ny to Fayetteville, Nc
  3. Take the bus from Fayetteville, Nc to Florence, Sc

$99 - $246

Drive  •  13 h 12 min

  1. Drive from Syracuse to Florence 775.4 miles

$75 - $110

Questions & Answers

The cheapest way to get from Syracuse to South Carolina is to drive which costs $75 - $110 and takes 13 h 12 min.

More details

The quickest way to get from Syracuse to South Carolina is to fly which costs $270 - $1,300 and takes 5 h 47 min.

More details

No, there is no direct bus from Syracuse to South Carolina. However, there are services departing from Syracuse, Ny and arriving at Florence, Sc via New York, Ny and Fayetteville, Nc. The journey, including transfers, takes approximately 22 h 25 min.

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No, there is no direct train from Syracuse to South Carolina station. However, there are services departing from Syracuse Regional Transportation Center and arriving at Florence Amtrak Station via Albany-Rensselaer Amtrak Station and New York Penn Station. The journey, including transfers, takes approximately 18 h 55 min.

More details

The distance between Syracuse and South Carolina is 691 miles. The road distance is 775.4 miles.

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The best way to get from Syracuse to South Carolina without a car is to night bus and train which takes 16 h 52 min and costs $110 - $320.

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It takes approximately 5 h 59 min to get from Syracuse to South Carolina, including transfers.

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Syracuse to South Carolina bus services, operated by Greyhound USA, depart from Syracuse, Ny station.

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Syracuse to South Carolina train services, operated by Amtrak, depart from Syracuse Regional Transportation Center station.

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The best way to get from Syracuse to South Carolina is to fly which takes 5 h 59 min and costs $220 - $1,100. Alternatively, you can train, which costs $160 - $430 and takes 18 h 55 min, you could also Thru-Bus and bus, which costs $95 - $140 and takes 19 h 15 min.

Mode details

Map of how to get from Syracuse to South Carolina.
Launch map view
  • Distance: 691 miles
  • Duration: 5 h 59 min

What companies run services between Syracuse, NY, USA and South Carolina, USA?

United Airlines, American Airlines and Delta fly from Syracuse to Greenville hourly. Alternatively, you can take a train from Syracuse to Florence via Albany-Rensselaer Amtrak Station and New York Penn Station in around 18 h 55 min.

Airlines
American Airlines
Website
aa.com
Flights from Syracuse to Greenville/Spartanburg via Philadelphia
Ave. Duration
5 h 12 min
When
Every day
Estimated price
$200 - $950
Flights from Syracuse to Greenville/Spartanburg via Charlotte
Ave. Duration
5 h 3 min
When
Every day
Estimated price
$190 - $950
Flights from Syracuse to Greenville/Spartanburg via Chicago O'Hare
Ave. Duration
6 h 28 min
When
Every day
Estimated price
$230 - $1,000
Flights from Syracuse to Greenville/Spartanburg via Reagan Washington
Ave. Duration
7 h 38 min
When
Saturday
Estimated price
$190 - $950
Flights from Syracuse to Florence via Charlotte
Ave. Duration
5 h 14 min
When
Every day
Estimated price
$260 - $1,200
Flights from Syracuse to Florence via Philadelphia, Charlotte
Ave. Duration
8 h 17 min
When
Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$260 - $1,300
Flights from Syracuse to Florence via Reagan Washington, Charlotte
Ave. Duration
7 h 50 min
When
Saturday
Estimated price
$260 - $1,300
Flights from Syracuse to Florence via Chicago O'Hare, Charlotte
Ave. Duration
8 h 26 min
When
Every day
Estimated price
$320 - $1,400
Flights from Syracuse to Charleston via Charlotte
Ave. Duration
5 h 5 min
When
Every day
Estimated price
$230 - $1,100
Flights from Syracuse to Charleston via Philadelphia
Ave. Duration
5 h 5 min
When
Every day
Estimated price
$240 - $1,100
Flights from Syracuse to Columbia via Charlotte
Ave. Duration
5 h 13 min
When
Every day
Estimated price
$230 - $1,100
Flights from Syracuse to Columbia via Philadelphia
Ave. Duration
6 h 38 min
When
Every day
Estimated price
$240 - $1,100
Flights from Syracuse to Columbia via Reagan Washington
Ave. Duration
7 h 37 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$230 - $1,100
Flights from Syracuse to Charlotte
Ave. Duration
2 h 27 min
When
Every day
Estimated price
$340 - $850
Flights from Syracuse to Charlotte via Philadelphia
Ave. Duration
4 h 43 min
When
Tuesday, Wednesday, Thursday, Friday, Saturday and Sunday
Estimated price
$340 - $850
Flights from Syracuse to Charlotte via Reagan Washington
Ave. Duration
4 h 43 min
When
Every day
Estimated price
$340 - $850
Delta
Website
delta.com
Flights from Syracuse to Greenville/Spartanburg via Detroit
Ave. Duration
5 h 42 min
When
Every day
Estimated price
$190 - $950
Flights from Syracuse to Greenville/Spartanburg via Atlanta
Ave. Duration
4 h 55 min
When
Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$200 - $950
Flights from Syracuse to Greenville/Spartanburg via New York La Guardia
Ave. Duration
5 h 50 min
When
Every day
Estimated price
$190 - $950
Flights from Syracuse to Charleston via New York La Guardia
Ave. Duration
5 h 39 min
When
Every day
Estimated price
$220 - $1,100
Flights from Syracuse to Charleston via New York JFK
Ave. Duration
5 h 23 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$220 - $1,100
Flights from Syracuse to Charleston via Detroit
Ave. Duration
5 h 46 min
When
Wednesday, Thursday, Friday, Saturday and Sunday
Estimated price
$240 - $1,200
Flights from Syracuse to Charleston via Atlanta
Ave. Duration
5 h 24 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$240 - $1,200
Flights from Syracuse to Columbia via Atlanta
Ave. Duration
5 h 6 min
When
Every day
Estimated price
$240 - $1,200
Flights from Syracuse to Columbia via New York La Guardia
Ave. Duration
4 h 52 min
When
Wednesday, Thursday, Friday and Sunday
Estimated price
$220 - $1,100
Flights from Syracuse to Charlotte via Detroit
Ave. Duration
4 h 45 min
When
Monday
Estimated price
$280 - $950
Flights from Syracuse to Charlotte via New York La Guardia
Ave. Duration
5 h 6 min
When
Wednesday, Thursday, Friday, Saturday and Sunday
Estimated price
$280 - $950
United Airlines
Website
united.com
Flights from Syracuse to Greenville/Spartanburg via Washington Dulles
Ave. Duration
4 h 27 min
When
Monday
Estimated price
$200 - $1,000
Flights from Syracuse to Greenville/Spartanburg via Newark
Ave. Duration
4 h 57 min
When
Tuesday, Wednesday, Thursday, Friday, Saturday and Sunday
Estimated price
$210 - $1,000
Flights from Syracuse to Greenville/Spartanburg via Chicago O'Hare
Ave. Duration
7 h 5 min
When
Every day
Estimated price
$240 - $1,100
Flights from Syracuse to Charleston via Washington Dulles
Ave. Duration
4 h 24 min
When
Monday, Wednesday, Thursday, Friday, Saturday and Sunday
Estimated price
$250 - $1,200
Flights from Syracuse to Charleston via Newark
Ave. Duration
5 h 52 min
When
Every day
Estimated price
$250 - $1,200
Flights from Syracuse to Charleston via Chicago O'Hare
Ave. Duration
6 h 51 min
When
Monday, Saturday and Sunday
Estimated price
$300 - $1,300
Flights from Syracuse to Columbia via Washington Dulles
Ave. Duration
6 h 10 min
When
Every day
Estimated price
$240 - $1,200
Flights from Syracuse to Columbia via Chicago O'Hare
Ave. Duration
7 h 32 min
When
Every day
Estimated price
$290 - $1,300
Flights from Syracuse to Charlotte via Washington Dulles
Ave. Duration
4 h 20 min
When
Every day
Estimated price
$270 - $1,100
Flights from Syracuse to Charlotte via Newark
Ave. Duration
4 h 47 min
When
Every day
Estimated price
$270 - $1,100
JetBlue Airways
Website
jetblue.com
Flights from Syracuse to Charleston via New York JFK
Ave. Duration
4 h 44 min
When
Every day
Estimated price
$220 - $1,100
Flights from Syracuse to Charleston via Boston
Ave. Duration
6 h 45 min
When
Every day
Estimated price
$250 - $1,100
Flights from Syracuse to Charlotte via Boston
Ave. Duration
5 h 9 min
When
Every day
Estimated price
$260 - $900
Train operators
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 215-856-7924
Website
amtrak.com
Train from Newark Penn Station to Florence Amtrak Station
Ave. Duration
11 h 27 min
Frequency
Twice daily
Estimated price
$90 - $250
Website
amtrak.com
Coach Seat
$90 - $140
Flexi Coach Seat
$160 - $230
Business Coach Seat
$180 - $250
Room
$370 - $550
Train from Syracuse Regional Transportation Center to Albany-Rensselaer Amtrak Station
Ave. Duration
2 h 40 min
Frequency
5 times a day
Estimated price
$35 - $85
Website
amtrak.com
Coach Seat
$35 - $55
Flexi Coach Seat
$60 - $90
Business Coach Seat
$55 - $85
Room
$180 - $250
Train from Albany-Rensselaer Amtrak Station to New York Penn Station
Ave. Duration
2 h 33 min
Frequency
Hourly
Estimated price
$40 - $85
Website
amtrak.com
Coach Seat
$40 - $85
Business Seat
$65 - $110
Bedroom
$270 - $330
Train from New York Penn Station to Florence Amtrak Station
Ave. Duration
11 h 50 min
Frequency
Twice daily
Estimated price
$90 - $260
Website
amtrak.com
Coach Seat
$90 - $140
Flexi Coach Seat
$160 - $230
Business Coach Seat
$180 - $260
Room
$370 - $550
VIA Rail
Phone
+1 1 888 842-7245
Website
viarail.ca
Train from Syracuse to Albany
Ave. Duration
4 h 7 min
Frequency
Once daily
Estimated price
$50 - $100
Website
viarail.ca
Escape
$30 - $55
Economy
$50 - $75
EconomyPlus
$70 - $100
Business
$75 - $110
Train from Albany to New York
Ave. Duration
2 h 35 min
Frequency
Once daily
Estimated price
$40 - $85
Website
viarail.ca
Coach Seat
$40 - $85
Business Seat
$65 - $110
Bedroom
$270 - $330
Bus operators
Charlotte Area Transit System
Phone
+1 704-336-7433
Email
telltransit@charlottenc.gov
Website
charlottenc.gov
Bus from Transit Center- Bay X to White Street Park and Ride
Ave. Duration
1 h 12 min
Frequency
3 times a day
Estimated price
$3 - $5
Schedules at
charlottenc.gov
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Night bus from Syracuse, Ny to Newark, Nj
Ave. Duration
4 h 25 min
Frequency
Once daily
Estimated price
$28 - $70
Website
greyhound.com
Economy
$28 - $45
Flexible
$50 - $70
Bus from Syracuse, Ny to New York, Ny
Ave. Duration
5 h 5 min
Frequency
Every 4 hours
Estimated price
$29 - $75
Website
greyhound.com
Economy
$29 - $50
Flexible
$55 - $75
Bus from New York, Ny to Fayetteville, Nc
Ave. Duration
13 h 45 min
Frequency
Every 4 hours
Estimated price
$55 - $140
Website
greyhound.com
Economy
$55 - $90
Flexible
$100 - $140
Bus from Fayetteville, Nc to Florence, Sc
Ave. Duration
1 h 35 min
Frequency
5 times a day
Estimated price
$14 - $35
Website
greyhound.com
Economy
$14 - $22
Flexible
$26 - $35
Greyhound Canada
Phone
+1 1-800-661-8747
Email
Canada.info@greyhound.ca
Website
greyhound.ca
Bus from Syracuse, NY to New York, NY - 625 8th Ave P.A. Terminal
Ave. Duration
4 h 30 min
Frequency
Every 4 hours
Estimated price
$25 - $65
Website
Greyhound.ca
Advanced Purchase
$25 - $40
Online Fare
$30 - $55
Standard Fare
$40 - $65
Refundable
$45 - $70
Trailways New York
Phone
(800) 858-8555
Website
trailwaysny.com
Bus from Syracuse, NY to New York, NY - Port Authority Bus Terminal
Ave. Duration
4 h 30 min
Frequency
4 times a day
Estimated price
$40 - $70
Book at
trailwaysny.com
Wanda Coach
Phone
6466307186
Email
help@wandacoach.com
Website
wandacoach.com
Bus from New York, NY to Florence, SC
Ave. Duration
12 h
Frequency
5 times a day
Estimated price
$55
Schedules at
wandacoach.com
Starline Bus
Website
starlinebus.com
Bus from New York, NY to Florence, SC
Ave. Duration
11 h 15 min
Frequency
Twice daily
Estimated price
$55
Schedules at
starlinebus.com
Book at
gotobus.com

Want to know more about travelling around United States

Rome2rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

More Questions & Answers

There is no direct flight from Syracuse Airport to Greenville/Spartanburg Airport. The quickest flight takes 4 h 27 min and has one stopover.

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Syracuse to South Carolina bus services, operated by Greyhound USA, arrive at Florence, Sc station.

More details

Syracuse to South Carolina train services, operated by Amtrak, arrive at Florence Amtrak Station.

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Yes, the driving distance between Syracuse to South Carolina is 775 miles. It takes approximately 13 h 12 min to drive from Syracuse to South Carolina.

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United Airlines, American Airlines and Delta offer flights from Syracuse Airport to Greenville/Spartanburg Airport.

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Book your Syracuse to South Carolina train tickets online with Rome2rio.

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Book your Syracuse to South Carolina bus tickets online with Greyhound, Greyhound and Greyhound.

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There are 18+ hotels available in South Carolina. Prices start at $49 USD per night.

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The best way to get from Syracuse to Syracuse Airport is to bus which takes 15 min and costs $8 - $12.

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