There are 7 ways to get from Syracuse to Chicago by plane, train, bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly Syracuse to Chicago O'Hare  •  4 h 7 min

  1. Fly from Syracuse (SYR) to Chicago O'Hare (ORD) SYR - ORD

$172 - $320

Cheapest option

Bus via Cleveland, Oh  •  15 h 44 min

  1. Take the bus from Syracuse, Ny to Buffalo, Ny 252 / ...
  2. Take the bus from Buffalo, Ny to Cleveland, Oh 248
  3. Take the bus from Cleveland, Oh to Chicago, Il

$81 - $205

5 alternative options

Fly Syracuse to Chicago Midway  •  5 h 30 min

  1. Fly from Syracuse (SYR) to Chicago Midway (MDW) SYR - MDW

$152 - $719

Train to Rochester, fly to Chicago O'Hare  •  5 h 59 min

  1. Take the train from Syracuse to Rochester
  2. Fly from Rochester (ROC) to Chicago O'Hare (ORD) ROC - ORD

$169 - $431

Train  •  12 h 56 min

  1. Take the train from Syracuse Regional Transportation Center to Chicago Union Station Lake Shore Limited

$95 - $270

Bus Greyhound Canada  •  19 h 7 min

  1. Take the bus from Syracuse, NY to Toronto, ON
  2. Take the bus from Toronto, ON to Chicago - Amtrak 5531

$86 - $182

Drive  •  11 h 24 min

  1. Drive from Syracuse to Chicago 680 miles

$65 - $100

Questions & Answers

No, there is no direct bus from Syracuse to Chicago. However, there are services departing from Syracuse, Ny and arriving at Chicago, Il via Buffalo, Ny and Cleveland, Oh. The journey, including transfers, takes approximately 15 h 44 min.

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Yes, there is a direct train departing from Syracuse Regional Transportation Center and arriving at Chicago Union Station station. Services depart twice daily, and operate every day. The journey takes approximately 12 h 56 min.

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The distance between Syracuse and Chicago is 594 miles. The road distance is 680 miles.

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The best way to get from Syracuse to Chicago without a car is to train which takes 12 h 56 min and costs .

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It takes approximately 4 h 7 min to get from Syracuse to Chicago, including transfers.

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Syracuse to Chicago bus services, operated by Greyhound USA, depart from Syracuse, Ny station.

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Syracuse to Chicago train services, operated by Amtrak, depart from Syracuse Regional Transportation Center station.

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The best way to get from Syracuse to Chicago is to fly which takes 4 h 7 min and costs . Alternatively, you can train, which costs and takes 12 h 56 min, you could also bus, which costs and takes 15 h 44 min.

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The quickest flight from Syracuse Airport to Chicago O'Hare Airport is the direct flight which takes 2 h 4 min.

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Syracuse to Chicago bus services, operated by Greyhound USA, arrive at Chicago, Il station.

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Map of how to get from Syracuse to Chicago.
Launch map view
  • Distance: 593.7 miles
  • Duration: 4 h 7 min

What companies run services between Syracuse, NY, USA and Chicago, IL, USA?

American Airlines, United Airlines and two other airlines fly from Syracuse to Chicago hourly. Alternatively, Amtrak operates a train from Syracuse to Chicago twice daily. Tickets cost $95 - $270 and the journey takes 12 h 56 min.

Airlines
Air Canada
Website
aircanada.com
Flights from Syracuse to Chicago O'Hare
Ave. Duration
2 h 10 min
When
Every day
Estimated price
$250 - $500
Flights from Syracuse to Chicago O'Hare via Toronto
Ave. Duration
3 h 59 min
When
Every day
Estimated price
$160 - $650
Flights from Rochester to Chicago O'Hare
Ave. Duration
1 h 54 min
When
Every day
Estimated price
$180 - $700
Flights from Rochester to Chicago O'Hare via Toronto
Ave. Duration
3 h 57 min
When
Every day
Estimated price
$140 - $600
United Airlines
Website
united.com
Flights from Syracuse to Chicago O'Hare
Ave. Duration
2 h 10 min
When
Every day
Estimated price
$250 - $500
Flights from Rochester to Chicago O'Hare
Ave. Duration
1 h 54 min
When
Every day
Estimated price
$180 - $700
Delta
Website
delta.com
Flights from Syracuse to Chicago O'Hare via Detroit
Ave. Duration
4 h
When
Every day
Estimated price
$220 - $550
Flights from Syracuse to Chicago Midway via Detroit
Ave. Duration
4 h 59 min
When
Every day
Estimated price
$140 - $700
Flights from Syracuse to Chicago Midway via Minneapolis
Ave. Duration
5 h 9 min
When
Monday to Friday
Estimated price
$170 - $800
Flights from Syracuse to Chicago Midway via Atlanta
Ave. Duration
6 h 13 min
When
Every day
Estimated price
$180 - $850
Flights from Syracuse to Chicago Midway via New York JFK, Detroit
Ave. Duration
7 h 33 min
When
Every day
Estimated price
$160 - $800
Flights from Rochester to Chicago O'Hare via Detroit
Ave. Duration
3 h 59 min
When
Every day
Estimated price
$160 - $800
American Airlines
Website
aa.com
Flights from Syracuse to Chicago O'Hare
Ave. Duration
2 h 11 min
When
Every day
Estimated price
$300 - $550
Flights from Rochester to Chicago O'Hare
Ave. Duration
2 h
When
Every day
Estimated price
$160 - $700
Train operators
VIA Rail
Phone
+1 1 888 842-7245
Website
viarail.ca
Train from Syracuse to Rochester
Ave. Duration
1 h 19 min
Frequency
Every 3 hours
Estimated price
$26 - $75
Website
viarail.ca
Escape
$26 - $40
Economy
$30 - $50
Economy Plus
$55 - $75
Business
$45 - $70
Business Plus/Sleeper
$85 - $130
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Syracuse Regional Transportation Center to Rochester Amtrak
Ave. Duration
1 h 14 min
Frequency
5 times a day
Estimated price
$27 - $60
Website
amtrak.com
Coach Seat
$27 - $40
Flexi Coach Seat
$45 - $70
Business Coach Seat
$40 - $60
Room
$150 - $210
Train from Syracuse Regional Transportation Center to Chicago Union Station
Ave. Duration
12 h 56 min
Frequency
Twice daily
Estimated price
$95 - $270
Website
amtrak.com
Coach Seat
$95 - $140
Flexi Coach Seat
$160 - $240
Business Coach Seat
$190 - $270
Room
$390 - $550
Bus operators
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Syracuse, Ny to Buffalo, Ny
Ave. Duration
3 h 20 min
Frequency
Every 15 minutes
Estimated price
$21 - $50
Website
greyhound.com
Economy
$21 - $35
Flexible
$35 - $50
Bus from Buffalo, Ny to Cleveland, Oh
Ave. Duration
4 h 10 min
Frequency
Every 30 minutes
Estimated price
$24 - $60
Website
greyhound.com
Economy
$24 - $40
Flexible
$45 - $60
Bus from Cleveland, Oh to Chicago, Il
Ave. Duration
7 h 35 min
Frequency
Hourly
Estimated price
$35 - $95
Website
greyhound.com
Economy
$35 - $60
Flexible
$70 - $95
Trailways New York
Phone
(800) 858-8555
Website
trailwaysny.com
Bus from Syracuse, NY to Toronto, ON
Ave. Duration
5 h 20 min
Frequency
Every 3 hours
Estimated price
$40 - $60
Book at
trailwaysny.com
Greyhound Canada
Phone
+1 1-800-661-8747
Email
Canada.info@greyhound.ca
Website
greyhound.ca
Bus from Toronto, ON to Chicago - Amtrak
Ave. Duration
11 h 35 min
Frequency
Once daily
Estimated price
$45 - $120
Website
Greyhound.ca
Advanced Purchase
$45 - $70
Online Fare
$60 - $90
Standard Fare
$75 - $120
Refundable
$85 - $130

Want to know more about travelling around United States

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More Questions & Answers

Chicago is 1 h behind Syracuse. It is currently 11:55 PM in Syracuse and 10:55 PM in Chicago.

Syracuse to Chicago train services, operated by Amtrak, arrive at Chicago Union Station.

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Yes, the driving distance between Syracuse to Chicago is 680 miles. It takes approximately 11 h 24 min to drive from Syracuse to Chicago.

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American Airlines, Delta, Air Canada and United Airlines offer flights from Syracuse Airport to Chicago O'Hare Airport.

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Book your Syracuse to Chicago train tickets online with Rome2rio.

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Book your Syracuse to Chicago bus tickets online with Greyhound, Greyhound and Greyhound.

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There are 580+ hotels available in Chicago. Prices start at $103 USD per night.

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The best way to get from Syracuse to Syracuse Airport is to bus which takes 15 min and costs .

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