There are 8 ways to get from Syracuse to Chicago by plane, train, bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly Syracuse to Chicago O'Hare  •  4 h 7 min

  1. Fly from Syracuse (SYR) to Chicago O'Hare (ORD) SYR - ORD

$172 - $320

Cheapest option

Bus  •  17 h 53 min

  1. Take the bus from Syracuse, Ny to Buffalo, Ny
  2. Take the bus from Buffalo, NY to Toronto, ON 300
  3. Take the bus from Toronto, On to Chicago, Il

$81 - $267

6 alternative options

Fly Syracuse to Chicago Midway  •  5 h 23 min

  1. Fly from Syracuse (SYR) to Chicago Midway (MDW) SYR - MDW

$152 - $719

Train to Rochester, fly to Chicago O'Hare  •  5 h 42 min

  1. Take the train from Syracuse Regional Transportation Center Amtrak to Rochester Amtrak
  2. Fly from Rochester (ROC) to Chicago O'Hare (ORD) ROC - ORD

$171 - $413

Bus to Buffalo, fly to Chicago Midway  •  6 h 7 min

  1. Take the bus from Syracuse, Ny to Buffalo, Ny
  2. Fly from Buffalo (BUF) to Chicago Midway (MDW) BUF - MDW

$155 - $468

Train  •  12 h 56 min

  1. Take the train from Syracuse Regional Transportation Center Amtrak to Chicago Union Station Amtrak Lake Shore Limited

$95 - $270

Train, bus  •  21 h 23 min

  1. Take the train from Syracuse to Toronto VIA Rail
  2. Take the bus from Toronto, ON to Chicago - Amtrak 5531

$91 - $249

Drive  •  11 h 24 min

  1. Drive from Syracuse to Chicago 680 miles

$65 - $100

Questions & Answers

The cheapest way to get from Syracuse to Chicago is to drive which costs $65 - $100 and takes 11 h 24 min.

More details

The quickest way to get from Syracuse to Chicago is to fly which costs $170 - $320 and takes 4 h 7 min.

More details

The distance between Syracuse and Chicago is 594 miles. The road distance is 680 miles.

Get driving directions

It takes approximately 4 h 7 min to get from Syracuse to Chicago, including transfers.

More details

No, there is no direct bus from Syracuse to Chicago. However, there are services departing from Syracuse, Ny and arriving at Chicago, Il via Buffalo, NY and Toronto, On. The journey, including transfers, takes approximately 17 h 53 min.

More details

Yes, there is a direct train departing from Syracuse Regional Transportation Center Amtrak and arriving at Chicago Union Station Amtrak station. Services depart twice daily, and operate every day. The journey takes approximately 12 h 56 min.

More details

What companies run services between Syracuse, NY, USA and Chicago, IL, USA?

United Airlines, American Airlines and three other airlines fly from Syracuse to Chicago hourly. Alternatively, Amtrak operates a train from Syracuse to Chicago twice daily. Tickets cost $95 - $270 and the journey takes 12 h 56 min.

Airlines
Air Canada
Website
aircanada.com
Flights from Syracuse to Chicago O'Hare
Ave. Duration
2 h 11 min
When
Every day
Estimated price
$250 - $500
Flights from Syracuse to Chicago O'Hare via Toronto
Ave. Duration
4 h
When
Every day
Estimated price
$160 - $650
Flights from Rochester to Chicago O'Hare
Ave. Duration
1 h 53 min
When
Every day
Estimated price
$180 - $700
Flights from Rochester to Chicago O'Hare via Toronto
Ave. Duration
4 h 5 min
When
Every day
Estimated price
$140 - $600
Delta
Website
delta.com
Flights from Syracuse to Chicago O'Hare via Detroit
Ave. Duration
3 h 53 min
When
Every day
Estimated price
$220 - $550
Flights from Syracuse to Chicago Midway via Detroit
Ave. Duration
3 h 36 min
When
Every day
Estimated price
$140 - $700
Flights from Syracuse to Chicago Midway via Atlanta
Ave. Duration
6 h 9 min
When
Every day
Estimated price
$180 - $850
Flights from Syracuse to Chicago Midway via Minneapolis
Ave. Duration
5 h 54 min
When
Every day
Estimated price
$170 - $800
Flights from Syracuse to Chicago Midway via New York JFK, Detroit
Ave. Duration
7 h 35 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$160 - $800
Flights from Rochester to Chicago O'Hare via Detroit
Ave. Duration
3 h 35 min
When
Every day
Estimated price
$160 - $800
Flights from Buffalo to Chicago Midway via Detroit
Ave. Duration
3 h 36 min
When
Every day
Estimated price
$130 - $800
United Airlines
Website
united.com
Flights from Syracuse to Chicago O'Hare
Ave. Duration
2 h 11 min
When
Every day
Estimated price
$250 - $500
Flights from Syracuse to Chicago O'Hare via Toronto
Ave. Duration
3 h 59 min
When
Every day
Estimated price
$160 - $650
Flights from Rochester to Chicago O'Hare
Ave. Duration
1 h 51 min
When
Every day
Estimated price
$180 - $700
Southwest Airlines
Website
southwest.com
Flights from Buffalo to Chicago Midway
Ave. Duration
1 h 38 min
When
Every day
Estimated price
$160 - $750
American Airlines
Website
aa.com
Flights from Syracuse to Chicago O'Hare
Ave. Duration
2 h 13 min
When
Every day
Estimated price
$300 - $550
Flights from Rochester to Chicago O'Hare
Ave. Duration
2 h
When
Every day
Estimated price
$160 - $700
Frontier Airlines
Website
flyfrontier.com
Flights from Syracuse to Chicago O'Hare
Ave. Duration
2 h 10 min
When
Sunday
Estimated price
$75 - $370
Train operators
Amtrak
Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Syracuse Regional Transportation Center Amtrak to Rochester Amtrak
Ave. Duration
1 h 10 min
Frequency
Every 4 hours
Estimated price
$27 - $60
Website
amtrak.com
Coach Seat
$27 - $40
Flexi Coach Seat
$45 - $70
Business Coach Seat
$40 - $60
Room
$150 - $210
Train from Syracuse Regional Transportation Center Amtrak to Chicago Union Station Amtrak
Ave. Duration
12 h 56 min
Frequency
Twice daily
Estimated price
$95 - $270
Website
amtrak.com
Coach Seat
$95 - $140
Flexi Coach Seat
$160 - $240
Business Coach Seat
$190 - $270
Room
$390 - $550
VIA Rail
Phone
+1 1 888 842-7245
Website
viarail.ca
Train from Syracuse to Rochester
Ave. Duration
1 h 14 min
Frequency
Every 3 hours
Estimated price
$25 - $75
Website
viarail.ca
Escape
$25 - $40
Economy
$30 - $45
Economy Plus
$50 - $75
Business
$45 - $65
Business Plus/Sleeper
$85 - $120
Train from Syracuse to Toronto
Ave. Duration
7 h 26 min
Frequency
Every 3 hours
Estimated price
$40 - $140
Website
viarail.ca
Escape
$40 - $60
Economy
$65 - $95
Economy Plus
$100 - $140
Business
$95 - $140
Business Plus/Sleeper
$170 - $250
Bus operators
Greyhound USA
Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Syracuse, Ny to Buffalo, Ny
Ave. Duration
2 h 30 min
Frequency
Hourly
Estimated price
$20 - $50
Website
greyhound.com
Economy
$20 - $35
Flexible
$35 - $50
Bus from Buffalo, Ny to Toronto, On
Ave. Duration
2 h 45 min
Frequency
Hourly
Estimated price
$16 - $40
Website
greyhound.com
Economy
$16 - $24
Flexible
$28 - $40
Bus from Toronto, On to Chicago, Il
Ave. Duration
11 h 45 min
Frequency
Hourly
Estimated price
$50 - $140
Website
greyhound.com
Economy
$50 - $85
Flexible
$100 - $140
Megabus Canada
Greyhound Canada
Phone
+1 1-800-661-8747
Email
Canada.info@greyhound.ca
Website
greyhound.ca
Bus from Toronto, ON to Chicago - Amtrak
Ave. Duration
11 h 35 min
Frequency
Once daily
Estimated price
$45 - $110
Website
Greyhound.ca
Advanced Purchase
$45 - $65
Online Fare
$60 - $90
Standard Fare
$75 - $110
Refundable
$85 - $120

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