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How to get fromSumter to St. Louisby bus, plane, bus (Greyhound, Flixbus, Amtrak), car, or bus (Greyhound, Flixbus)

Find Transport to St. Louis

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There are 7 ways to get from Sumter to St. Louis by bus, plane, bus (Greyhound, Flixbus, Amtrak), car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Charlotte Douglas International Airport, fly

    best
    1. Take the bus from Sumter Bus Stop to Charlotte Bus Stationbus bus
    2. Fly from Charlotte Douglas International Airport (CLT) to Lambert–St. Louis International Airport (STL)plane plane CLT - STL
    7h 4m
    $117–582

  2. Bus to Columbia, fly

    cheapest
    1. Take the bus from James E Clyburn Intermodal Transportation Center to Laurel Sumter Eastbus bus
    2. Fly from Columbia (CAE) to Lambert–St. Louis International Airport (STL)plane plane CAE - STL
    8h 24m
    $102–556

  3. Bus via Carbondale

    1. Take the bus from Sumter Bus Stop to Camdenbus bus
    2. Take the bus from Camden to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Carbondale Intermodal Stationbus bus
    4. Take the bus from Carbondale to St. Louisbus bus
    19h 16m
    $118–212

  4. Drive  786.6 mi

    1. Drive from Sumter to St. Louiscar car 786.6 mi
    13h 31m
    $144–208

  5. Bus to Charleston International Airport, fly

    1. Take the bus from Sumter Bus Stop to Charleston Bus Stationbus bus
    2. Fly from Charleston International Airport (CHS) to Lambert–St. Louis International Airport (STL)plane plane CHS - STL
    9h 19m
    $142–647

  6. Bus, bus to Myrtle Beach, fly

    1. Take the bus from Sumter Bus Stop to Camdenbus bus
    2. Take the bus from Camden to Myrtle Beach Bus Stationbus bus
    3. Fly from Myrtle Beach (MYR) to Lambert–St. Louis International Airport (STL)plane plane MYR - STL
    10h 39m
    $126–543

  7. Bus

    1. Take the bus from Sumter Bus Stop to Camdenbus bus
    2. Take the bus from Camden to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus
    19h 35m
    $119–212

Sumter to St. Louis by bus

Calendar5Weekly Buses
Duration19h 16mAverage Duration
Ticket$118Cheapest Price
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Comparing Your Travel Options

Map of how to get from Sumter to St. Louis.ExpandLaunch map view
  • Distance: 701.7 mi
  • Duration: 7h 4m

What companies run services between Sumter, SC, USA and St. Louis, MO, USA?

You can take a bus from Sumter Bus Stop to St. Louis via Camden, Atlanta Bus Station, and Carbondale in around 19h 16m.

Airlines
Bus operators

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