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How to get fromSumter to St. Louisby bus, plane, bus (Flixbus), car or bus (Greyhound)

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There are 6 ways to get from Sumter to St. Louis by bus, plane, bus (Flixbus), car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Florence Regional Airport, fly

    best
    1. Take the bus from Sumter to Florencebus
    2. Fly from Florence Regional Airport (FLO) to Lambert–St. Louis International Airport (STL)planeFLO - STL
    6h 52m
    $142–709

  2. Bus

    1. Take the bus from Sumter to Columbiabus
    2. Take the bus from Columbia to Atlantabus
    3. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus
    18h 11m
    $146–393

  3. Drive 786.5 mi

    1. Drive from Sumter to St. Louiscar786.5 mi
    13h 24m
    $144–208

  4. Bus to Charlotte Douglas International Airport, fly

    1. Take the bus from Sumter to Charlotte Bus Stationbus
    2. Fly from Charlotte Douglas International Airport (CLT) to Lambert–St. Louis International Airport (STL)planeCLT - STL
    8h 3m
    $258–477

  5. Bus to Columbia, fly

    1. Take the bus from James E Clyburn Intermodal Transportation Center to Laurel Sumter Eastbus
    2. Fly from Columbia (CAE) to Lambert–St. Louis International Airport (STL)planeCAE - STL
    8h 47m
    $166–906

  6. Bus via Columbus

    1. Take the bus from Sumter to Charlotte Bus Stationbus
    2. Take the bus from Charlotte Bus Station to Columbus Bus Stationbus
    3. Take the bus from Columbus Bus Station to St Louis Bus Stationbus
    24h 30m
    $146–328

Sumter to St. Louis by bus

Calendar7Weekly Buses
Duration18h 11mAverage Duration
Ticket$146Cheapest Price
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Questions & Answers

What companies run services between Sumter, SC, USA and St. Louis, MO, USA?

You can take a bus from Sumter to St Louis Bus Station via Columbia, Atlanta, and Atlanta Bus Station in around 18h 11m.

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