Rome2Rio

How to get fromSumter to St. Louisby bus, plane, bus (Flixbus), car or bus (Greyhound)

Find Transport to St. Louis

See all options

There are 6 ways to get from Sumter to St. Louis by bus, plane, bus (Flixbus), car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Florence Regional Airport, fly

    best
    1. Take the bus from Sumter to Florencebus bus
    2. Fly from Florence Regional Airport (FLO) to Lambert–St. Louis International Airport (STL)plane plane FLO - STL
    7h 8m
    $142–759

  2. Bus to Columbia, fly

    cheapest
    1. Take the bus from James E Clyburn Intermodal Transportation Center to Laurel Sumter Eastbus bus
    2. Fly from Columbia (CAE) to Lambert–St. Louis International Airport (STL)plane plane CAE - STL
    8h 48m
    $116–656

  3. Bus

    1. Take the bus from Sumter to Columbiabus bus
    2. Take the bus from Columbia to Atlantabus bus
    3. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus
    18h 11m
    $141–383

  4. Drive 786.5 mi

    1. Drive from Sumter to St. Louiscar car 786.5 mi
    13h 32m
    $144–208

  5. Bus to Charlotte Douglas International Airport, fly

    1. Take the bus from Sumter to Charlotte Bus Stationbus bus
    2. Fly from Charlotte Douglas International Airport (CLT) to Lambert–St. Louis International Airport (STL)plane plane CLT - STL
    8h 7m
    $258–497

  6. Bus via Columbus

    1. Take the bus from Sumter to Charlotte Bus Stationbus bus
    2. Take the bus from Charlotte Bus Station to Columbusbus bus
    3. Take the bus from Columbus to St Louis Bus Stationbus bus
    24h 40m
    $136–398

Sumter to St. Louis by bus

Calendar7Weekly Buses
Duration18h 11mAverage Duration
Ticket$141Cheapest Price
See schedules

Questions & Answers

What companies run services between Sumter, SC, USA and St. Louis, MO, USA?

You can take a bus from Sumter to St Louis Bus Station via Columbia, Atlanta, and Atlanta Bus Station in around 18h 11m.

Airlines
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers

Trips from Sumter

Trips to St. Louis

Popular routes