There are 10 ways to get from Sumter to Key West by bus, plane, bus (Flixbus, Greyhound), train, shuttle, car, or taxi
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus to Florence Regional Airport, fly
best- Take the bus from Sumter to Florence
- Fly from Florence Regional Airport (FLO) to Key West International Airport (EYW)FLO - EYW
6h 17m$120–549Bus to Columbia, fly
cheapest- Take the bus from James E Clyburn Intermodal Transportation Center to Laurel Sumter East
- Fly from Columbia (CAE) to Key West International Airport (EYW)CAE - EYW
8h 8m$100–506Bus
- Take the bus from Sumter to Florence
- Take the bus from Florence Bus Station to Orlando Bus Station
- Take the bus from Orlando Bus Station to Miami Airport Station
- Take the bus from Miami Airport Station to Big Pine Key
- Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd StreetLks
23h 13m$130–306Bus, train, shuttle
- Take the bus from Sumter to Columbia
- Take the bus from Columbia to Charleston Amtrak Station
- Take the train from Charleston Amtrak Station to West Palm Beach Amtrak Station
- Take the bus from West Palm Beach, FL to Fort Lauderdale Airport
- Take a shuttle bus from Fort Lauderdale, FL - International Airport to Key West, FL
26h 25m$306–617Drive 777.5 mi
- Drive from Sumter to Key West777.5 mi
13h 34m$142–205Bus to Charlotte Douglas International Airport, fly
- Take the bus from Sumter to Charlotte Bus Station
- Fly from Charlotte Douglas International Airport (CLT) to Key West International Airport (EYW)CLT - EYW
7h 40m$126–517Bus, bus to Augusta Regional Airport At Bush Field, fly
- Take the bus from Sumter to Columbia
- Take the bus from Columbia to Augusta
- Fly from Augusta Regional Airport At Bush Field (AGS) to Key West International Airport (EYW)AGS - EYW
8h 24m$159–663Bus, bus to Myrtle Beach, fly
- Take the bus from Sumter to Florence
- Take the bus from Florence Bus Station to Myrtle Beach Bus Station
- Fly from Myrtle Beach (MYR) to Key West International Airport (EYW)MYR - EYW
8h 56m$136–654Taxi, train, bus
- Take the taxi from Sumter to Camden Amtrak Station
- Take the train from Camden Amtrak Station to Hollywood Amtrak Station
- Take the bus from Miami Airport Station to Big Pine Key
- Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd StreetLks
26h 49m$189–389Bus, train
- Take the bus from Sumter to Florence
- Take the bus from Florence Bus Station to Charleston Bus Station
- Take the train from Charleston Amtrak Station to Hollywood Amtrak Station
- Take the bus from Miami Airport Station to Big Pine Key
- Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd StreetLks
27h 44m$180–392
Sumter to Key West by bus and foot
Questions & Answers
The cheapest way to get from Sumter to Key West is to drive which costs $140 - $210 and takes 13h 34m.
The fastest way to get from Sumter to Key West is to bus and fly which takes 6h 17m and costs $120 - $550.
No, there is no direct bus from Sumter to Key West. However, there are services departing from Sumter and arriving at N Roosevelt & 3rd Street via Florence Bus Station, Orlando Bus Station, Miami Airport Station and Big Pine Key - CVS / MM30. The journey, including transfers, takes approximately 23h 13m.
The distance between Sumter and Key West is 726 miles. The road distance is 782 miles.
The best way to get from Sumter to Key West without a car is to bus which takes 23h 13m and costs $130 - $310.
It takes approximately 6h 17m to get from Sumter to Key West, including transfers.
Sumter to Key West bus services, operated by Southeastern Stages, depart from Sumter station.
Sumter to Key West bus services, operated by Southeastern Stages, arrive at Florence station.
Yes, the driving distance between Sumter to Key West is 782 miles. It takes approximately 13h 34m to drive from Sumter to Key West.
There are 862+ hotels available in Key West.
What companies run services between Sumter, SC, USA and Key West, FL, USA?
You can take a bus from Sumter to N Roosevelt & 3rd Street via Florence, Florence Bus Station, Orlando Bus Station, Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 23h 13m.
- Website
- aa.com
Flights from Florence Regional Airport to Key West International Airport via Charlotte Douglas International Airport
- Ave. Duration
- 5h 7m
- When
- Every day
- Estimated price
- $80–430
Flights from Columbia to Key West International Airport via Miami
- Ave. Duration
- 4h 32m
- When
- Saturday
- Estimated price
- $85–500
Flights from Columbia to Key West International Airport via Charlotte Douglas International Airport
- Ave. Duration
- 5h 23m
- When
- Every day
- Estimated price
- $95–550
Flights from Columbia to Key West International Airport via Reagan Washington
- Ave. Duration
- 8h 32m
- When
- Every day
- Estimated price
- $140–700
Flights from Charlotte Douglas International Airport to Key West International Airport
- Ave. Duration
- 2h 21m
- When
- Every day
- Estimated price
- $70–400
Flights from Charlotte Douglas International Airport to Key West International Airport via Miami
- Ave. Duration
- 4h 38m
- When
- Every day
- Estimated price
- $70–410
Flights from Augusta Regional Airport At Bush Field to Key West International Airport via Charlotte Douglas International Airport
- Ave. Duration
- 5h 30m
- When
- Every day
- Estimated price
- $80–440
Flights from Myrtle Beach to Key West International Airport via Charlotte Douglas International Airport
- Ave. Duration
- 5h 26m
- When
- Every day
- Estimated price
- $80–440
- Website
- delta.com
Flights from Columbia to Key West International Airport via Atlanta
- Ave. Duration
- 4h 48m
- When
- Every day
- Estimated price
- $95–550
Flights from Charlotte Douglas International Airport to Key West International Airport via Atlanta
- Ave. Duration
- 5h 3m
- When
- Every day
- Estimated price
- $75–430
Flights from Augusta Regional Airport At Bush Field to Key West International Airport via Atlanta
- Ave. Duration
- 4h 41m
- When
- Every day
- Estimated price
- $75–430
Flights from Myrtle Beach to Key West International Airport via Atlanta
- Ave. Duration
- 5h 50m
- When
- Every day
- Estimated price
- $85–450
- Website
- allegiantair.com
Flights from Columbia to Key West International Airport via Orlando Sanford
- Ave. Duration
- 4h 16m
- When
- Sunday
- Estimated price
- $85–490
- Website
- spirit.com
Flights from Charlotte Douglas International Airport to Key West International Airport via Fort Lauderdale-Hollywood International
- Ave. Duration
- 3h 50m
- When
- Thursday and Sunday
- Estimated price
- $75–400
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Charleston Amtrak Station to West Palm Beach Amtrak Station
- Ave. Duration
- 12h 14m
- Frequency
- Once daily
- Estimated price
- $70–140
- Website
- https://www.amtrak.com/home.html
Train from Camden Amtrak Station to Hollywood Amtrak Station
- Ave. Duration
- 18h 9m
- Frequency
- Once daily
- Estimated price
- $70–240
- Website
- https://www.amtrak.com/home.html
- Coach Seat - Advance Purchase
- $70–200
- Coach Seat short notice purchase
- $100–240
- Business - advance purchase
- $140–600
- Business Class
- $220–550
Train from Charleston Amtrak Station to Hollywood Amtrak Station
- Ave. Duration
- 13h 25m
- Frequency
- Once daily
- Estimated price
- $100–190
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 404-591-2750
- info@southeasternstages.com
- Website
- southeasternstages.com
Bus from Sumter to Florence
- Ave. Duration
- 55 min
- Frequency
- Once daily
- Estimated price
- $19–95
- Schedules at
- southeasternstages.com
Bus from Sumter to Columbia
- Ave. Duration
- 1h
- Frequency
- Once daily
- Estimated price
- $21–95
- Schedules at
- southeasternstages.com
Bus from Columbia to Charleston Amtrak Station
- Ave. Duration
- 2h 45m
- Frequency
- Once daily
- Estimated price
- $35–100
- Schedules at
- southeasternstages.com
Bus from Sumter to Charlotte Bus Station
- Ave. Duration
- 3h 30m
- Frequency
- Once daily
- Estimated price
- $40–100
- Schedules at
- southeasternstages.com
Bus from Columbia to Augusta
- Ave. Duration
- 1h 10m
- Frequency
- 3 times a day
- Estimated price
- $26–95
- Schedules at
- southeasternstages.com
Bus from Florence Bus Station to Myrtle Beach Bus Station
- Ave. Duration
- 1h 25m
- Frequency
- Once daily
- Estimated price
- $25–95
- Schedules at
- southeasternstages.com
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Florence Bus Station to Orlando Bus Station
- Ave. Duration
- 8h 55m
- Frequency
- Once daily
- Estimated price
- $60–130
- Schedules at
- flixbus.com
Bus from Orlando Bus Station to Miami Airport Station
- Ave. Duration
- 4h 50m
- Frequency
- Hourly
- Estimated price
- $28–50
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Orlando Bus Station to Miami Airport Station
- Ave. Duration
- 6h 20m
- Frequency
- 4 times a day
- Estimated price
- $28–45
- Website
- https://www.greyhound.com/
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 35m
- Frequency
- Twice daily
- Estimated price
- $21–29
- Website
- https://www.greyhound.com/
Bus from Florence Bus Station to Myrtle Beach Bus Station
- Ave. Duration
- 1h 20m
- Frequency
- Once daily
- Estimated price
- $16–19
- Website
- https://www.greyhound.com/
Bus from Florence Bus Station to Charleston Bus Station
- Ave. Duration
- 3h 25m
- Frequency
- Once daily
- Estimated price
- $35–70
- Website
- https://www.greyhound.com/
- Phone
- +1 (305) 600-1455
- Website
- cityofkeywest-fl.gov
Bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Street
- Ave. Duration
- 1h 9m
- Frequency
- Every 3 hours
- Estimated price
- $2–4
- Schedules at
- https://www.cityofkeywest-fl.gov/595/Schedules-and-Route-Maps
- Phone
- +1 877 733 0724
- Website
- redcoachusa.com
Bus from West Palm Beach, FL to Fort Lauderdale Airport
- Ave. Duration
- 50 min
- Frequency
- Twice daily
- Estimated price
- $8–50
- Website
- https://www.redcoachusa.com
- Web
- $8–50
- Phone
- +1 (305) 289-9997
- groups@keysshuttle.com
- Website
- keysshuttle.com
Shuttle from Fort Lauderdale, FL - International Airport to Key West, FL
- Ave. Duration
- 4h 30m
- Frequency
- 4 times a day
- Estimated price
- $170–230
- Website
- https://www.keysshuttle.com
- Phone
- +1 803-255-7100
- Website
- catchthecometsc.gov
Bus from James E Clyburn Intermodal Transportation Center to Laurel Sumter East
- Ave. Duration
- 1h 18m
- Frequency
- Once daily
- Estimated price
- $2
- Schedules at
- catchthecometsc.gov
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