There are 9 ways to get from Sumter to Gainesville by bus (Flixbus), taxi, train, bus, car, plane, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Sumter to Florencebus
- Take the bus from Florence Bus Station to Jacksonvillebus
- Take the bus from Jacksonville to Gainesvillebus
9h 50m$85–201Bus to Columbia, fly to Gainesville Regional Airport
cheapest- Take the bus from James E Clyburn Intermodal Transportation Center to Laurel Sumter Eastbus
- Fly from Columbia (CAE) to Gainesville Regional Airport (GNV)plane CAE - GNV
8h 27m$60–346Taxi, train, bus
- Take the taxi from Sumter to Camden Stationtaxi
- Take the train from Camden Station to Jacksonvilletrain
- Take the bus from Jacksonville to Gainesvillebus
10h 54m$185–336Drive 338.4 mi
- Drive from Sumter to Gainesvillecar 338.4 mi
5h 56m$62–90Bus to Florence Regional Airport, fly to Gainesville Regional Airport
- Take the bus from Sumter to Florencebus
- Fly from Florence Regional Airport (FLO) to Gainesville Regional Airport (GNV)plane FLO - GNV
9h 15m$86–448Bus via Macon
- Take the bus from Sumter to Columbiabus
- Take the bus from Columbia to Macon Bus Stationbus
- Take the bus from Macon Bus Station to Gainesville Bus Stopbus
15h 13m$143–290Bus to Charlotte Douglas International Airport, fly to Gainesville Regional Airport
- Take the bus from Sumter to Charlotte Bus Stationbus
- Fly from Charlotte Douglas International Airport (CLT) to Gainesville Regional Airport (GNV)plane CLT - GNV
8h 23m$92–416Bus to Charlotte Douglas International Airport, fly to Jacksonville, bus
- Take the bus from Sumter to Charlotte Bus Stationbus
- Fly from Charlotte Douglas International Airport (CLT) to Jacksonville (JAX)plane CLT - JAX
- Take the bus from Jacksonville to Gainesvillebus
10h 50m$372–590Bus to Charlotte Douglas International Airport, fly to Orlando, bus
- Take the bus from Sumter to Charlotte Bus Stationbus
- Fly from Charlotte Douglas International Airport (CLT) to Orlando (MCO)plane CLT - MCO
- Take the bus from Orlando RedCoach Station to Gainesvillebus
10h 29m$109–466
Sumter to Gainesville by bus
Questions & Answers
The cheapest way to get from Sumter to Gainesville is to drive which costs $60 - $90 and takes 5h 56m.
The fastest way to get from Sumter to Gainesville is to drive which takes 5h 56m and costs $60 - $90.
No, there is no direct bus from Sumter to Gainesville. However, there are services departing from Sumter and arriving at Gainesville via Florence Bus Station and Jacksonville. The journey, including transfers, takes approximately 9h 50m.
The distance between Sumter and Gainesville is 425 miles. The road distance is 340.4 miles.
The best way to get from Sumter to Gainesville without a car is to bus which takes 9h 50m and costs $85 - $210.
It takes approximately 9h 50m to get from Sumter to Gainesville, including transfers.
Sumter to Gainesville bus services, operated by Southeastern Stages, depart from Sumter station.
Sumter to Gainesville bus services, operated by Southeastern Stages, arrive at Florence station.
Yes, the driving distance between Sumter to Gainesville is 340 miles. It takes approximately 5h 56m to drive from Sumter to Gainesville.
There are 248+ hotels available in Gainesville.
What companies run services between Sumter, SC, USA and Gainesville, FL, USA?
You can take a bus from Sumter to Gainesville via Florence, Florence Bus Station, and Jacksonville in around 9h 50m.
- Website
- aa.com
Flights from Florence Regional Airport to Gainesville Regional Airport via Charlotte Douglas International Airport
- Ave. Duration
- 6h 4m
- When
- Every day
- Estimated price
- $55–340
Flights from Florence Regional Airport to Gainesville Regional Airport via Charlotte Douglas International Airport, Dallas/Ft.Worth
- Ave. Duration
- 9h 42m
- When
- Every day
- Estimated price
- $130–600
Flights from Florence Regional Airport to Gainesville Regional Airport via Charlotte Douglas International Airport, Miami
- Ave. Duration
- 12h 15m
- When
- Saturday
- Estimated price
- $85–440
Flights from Columbia to Gainesville Regional Airport via Charlotte Douglas International Airport
- Ave. Duration
- 4h 23m
- When
- Every day
- Estimated price
- $55–340
Flights from Columbia to Gainesville Regional Airport via Reagan Washington, Charlotte Douglas International Airport
- Ave. Duration
- 7h 13m
- When
- Every day
- Estimated price
- $90–460
Flights from Charlotte Douglas International Airport to Gainesville Regional Airport
- Ave. Duration
- 1h 42m
- When
- Every day
- Estimated price
- $45–310
Flights from Charlotte Douglas International Airport to Jacksonville
- Ave. Duration
- 1h 27m
- When
- Every day
- Estimated price
- $60–400
Flights from Charlotte Douglas International Airport to Orlando
- Ave. Duration
- 1h 50m
- When
- Every day
- Estimated price
- $45–290
- Website
- delta.com
Flights from Columbia to Gainesville Regional Airport via Atlanta
- Ave. Duration
- 4h 3m
- When
- Every day
- Estimated price
- $55–340
Flights from Charlotte Douglas International Airport to Gainesville Regional Airport via Atlanta
- Ave. Duration
- 3h 55m
- When
- Every day
- Estimated price
- $55–330
Flights from Charlotte Douglas International Airport to Jacksonville via Atlanta
- Ave. Duration
- 3h 27m
- When
- Every day
- Estimated price
- $70–440
- Website
- flyfrontier.com
Flights from Charlotte Douglas International Airport to Orlando
- Ave. Duration
- 1h 56m
- When
- Every day
- Estimated price
- $45–290
- Website
- spirit.com
Flights from Charlotte Douglas International Airport to Orlando
- Ave. Duration
- 1h 49m
- When
- Every day
- Estimated price
- $40–220
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Camden Station to Jacksonville
- Ave. Duration
- 6h 48m
- Frequency
- Once daily
- Estimated price
- $75–200
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 404-591-2750
- info@southeasternstages.com
- Website
- southeasternstages.com
Bus from Sumter to Florence
- Ave. Duration
- 55 min
- Frequency
- Once daily
- Estimated price
- $19–95
- Schedules at
- southeasternstages.com
Bus from Sumter to Columbia
- Ave. Duration
- 1h
- Frequency
- Once daily
- Estimated price
- $21–95
- Schedules at
- southeasternstages.com
Bus from Columbia to Macon Bus Station
- Ave. Duration
- 5h 40m
- Frequency
- Once daily
- Estimated price
- $80–110
- Schedules at
- southeasternstages.com
Bus from Sumter to Charlotte Bus Station
- Ave. Duration
- 3h 30m
- Frequency
- Once daily
- Estimated price
- $40–100
- Schedules at
- southeasternstages.com
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Florence Bus Station to Jacksonville
- Ave. Duration
- 5h 25m
- Frequency
- Once daily
- Estimated price
- $50–85
- Schedules at
- flixbus.com
Bus from Jacksonville to Gainesville
- Ave. Duration
- 1h 30m
- Frequency
- 6 times a week
- Estimated price
- $16–23
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Macon Bus Station to Gainesville Bus Stop
- Ave. Duration
- 5h 10m
- Frequency
- Once daily
- Estimated price
- $40–85
- Website
- https://www.greyhound.com/
- Phone
- +1 803-255-7100
- Website
- catchthecometsc.gov
Bus from James E Clyburn Intermodal Transportation Center to Laurel Sumter East
- Ave. Duration
- 1h 18m
- Frequency
- Once daily
- Estimated price
- $2
- Schedules at
- catchthecometsc.gov
- Phone
- +1 877 733 0724
- Website
- redcoachusa.com
Bus from Orlando RedCoach Station to Gainesville
- Ave. Duration
- 1h 55m
- Frequency
- Every 4 hours
- Estimated price
- $22–140
- Website
- https://www.redcoachusa.com
- Web
- $22–140
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide














