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There are 4 ways to get from St. Petersburg to Key West by bus, ferry, car or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Bus, ferry via Marco Island, FL  •  8 h 18 min

  1. Take the bus from Bradenton, FL to Naples, FL Javax Bus
  2. Take the ferry from Marco Island, FL to Key West, FL Marco Island

$204 - $228

Cheapest option

Line 79 bus, fly  •  6 h 19 min

  1. Take the line 79 bus from 34Th St S + 2Nd Ave S to Ulmerton Rd + 60Th St N
  2. Fly from Tampa (TPA) to Key West (EYW) TPA - EYW

$107 - $439

2 alternative options

Bus, ferry  •  9 h 45 min

  1. Take the bus from Bradenton, FL - McDonalds to Fort Myers, FL - McDonalds 303 / ...
  2. Take the ferry from Fort Myers Beach, FL to Key West, FL Fort Myers Beach

$144 - $186

Drive  •  7 h 30 min

  1. Drive from St. Petersburg to Key West 407.6 miles

$40 - $60

Questions & Answers

The cheapest way to get from St. Petersburg to Key West is to drive which costs $40 - $60 and takes 7 h 30 min.

More details

The quickest way to get from St. Petersburg to Key West is to line 79 bus and fly which costs $100 - $440 and takes 6 h 19 min.

More details

The distance between St. Petersburg and Key West is 230 miles. The road distance is 407.6 miles.

Get driving directions

The best way to get from St. Petersburg to Key West without a car is to bus and ferry which takes 8 h 18 min and costs $200 - $230.

More details

It takes approximately 8 h 18 min to get from St. Petersburg to Key West, including transfers.

More details

The quickest flight from Tampa Airport to Key West Airport is the direct flight which takes 1 h 25 min.

Search flights

Yes, the driving distance between St. Petersburg to Key West is 408 miles. It takes approximately 7 h 30 min to drive from St. Petersburg to Key West.

Get driving directions

Silver Airways and American Airlines offer flights from Tampa Airport to Key West Airport.

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There are 340+ hotels available in Key West. Prices start at $129 USD per night.

More details

Map of how to get from St. Petersburg to Key West.
Launch map view
  • Distance: 230.4 miles
  • Duration: 8 h 18 min

What companies run services between St. Petersburg, FL, USA and Key West, FL, USA?

There is no direct connection from St. Petersburg to Key West. However, you can take the bus to 13th St W/6th Ave W, take the line 3 bus to 67th St Cir E/6th Ave E, take the walk to Bradenton, FL, take the bus to Naples, FL, take the taxi to Marco Island, FL, then take the ferry to Key West, FL. Alternatively, you can take a vehicle from St. Petersburg to Key West via 13th St W/6th Ave W, 67th St Cir E/6th Ave E, Bradenton, FL - McDonalds, Fort Myers, FL - McDonalds, Daniels Parkway @ Danport Boulevard, Winkler Road @ Summerlin Road, and Fort Myers Beach, FL in around 9 h 45 min.

Airlines
American Airlines
Website
aa.com
Flights from Tampa to Key West via Miami
Ave. Duration
3 h 10 min
When
Every day
Estimated price
$250 - $1,100
Silver Airways
Website
silverairways.com
Flights from Tampa to Key West
Ave. Duration
1 h 25 min
When
Every day
Estimated price
$200 - $850
Bus operators
Javax Bus
Phone
407-299-6360
Email
info@floridatransportation.net
Website
javaxbus.com
Bus from Bradenton, FL to Naples, FL
Ave. Duration
1 h 45 min
Frequency
4 times a day
Estimated price
$49
Schedules at
javaxbus.com
Book at
gotobus.com
The Florida Express Bus
Phone
407-442-2810
Website
busticketreservations.com
Bus from Bradenton, FL - McDonalds to Fort Myers, FL - McDonalds
Ave. Duration
1 h 30 min
Frequency
Twice daily
Estimated price
$27 - $60
More information at
American Bus Tickets
Pinellas Suncoast Transit Authority
Phone
+1 727-540-1900
Email
ride@psta.net
Website
psta.net
Bus from 34Th St S + 2Nd Ave S to Ulmerton Rd + 60Th St N
Ave. Duration
1 h 3 min
Frequency
Hourly
Estimated price
$3
Schedules at
psta.net
Ferry operators
Key West Express
Phone
+1 239-463-5733
Website
keywestexpress.net
Ferry from Marco Island, FL to Key West, FL
Ave. Duration
2 h 30 min
Frequency
Once daily
Estimated price
$95
Book at
Key West Express
Ferry from Fort Myers Beach, FL to Key West, FL
Ave. Duration
3 h 30 min
Frequency
Once daily
Estimated price
$95
Book at
Key West Express

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