There are 7 ways to get from St. Louis to Zacatecas by plane, bus, train or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly to Zacatecas  •  8 h 12 min

  1. Fly from St. Louis (STL) to Zacatecas (ZCL) STL - ZCL

$362 - $1,216

Cheapest option

Bus  •  38 h 50 min

  1. Take the bus from St Louis, Mo to Oklahoma City, Ok
  2. Take the bus from Oklahoma City, Ok to Dallas, Tx
  3. Take the bus from Dallas, Tx to Nuevo Laredo, Mx
  4. Take the bus from Nuevo Laredo to Monterrey
  5. Take the bus from Monterrey to Zacatecas

$165 - $374

5 alternative options

Fly to Aguascalientes, bus  •  10 h 9 min

  1. Fly from St. Louis (STL) to Aguascalientes (AGU) STL - AGU
  2. Take the bus from Aguascalientes to Zacatecas

$292 - $1,636

Fly to San Luis Potosi, bus  •  11 h 6 min

  1. Fly from St. Louis (STL) to San Luis Potosi (SLP) STL - SLP
  2. Take the bus from San Luis Potosí to Zacatecas

$254 - $1,434

Train, bus  •  40 h 4 min

  1. Take the train from St. Louis Gateway Station to San Antonio Amtrak
  2. Take the bus from San Antonio, Tx to Laredo, Tx
  3. Take the bus from Nuevo Laredo to Zacatecas

$201 - $523

Train, bus via Monterrey  •  43 h 20 min

  1. Take the train from St. Louis Gateway Station to San Antonio Amtrak
  2. Take the bus from San Antonio to Nuevo Laredo
  3. Take the bus from Nuevo Laredo to Monterrey
  4. Take the bus from Monterrey to Zacatecas

$226 - $518

Drive  •  25 h 34 min

  1. Drive from St. Louis to Zacatecas 1503.9 miles

$200 - $300

Questions & Answers

The cheapest way to get from St. Louis to Zacatecas is to drive which costs $200 - $300 and takes 25 h 34 min.

More details

The quickest way to get from St. Louis to Zacatecas is to fly which costs $360 - $1,300 and takes 8 h 12 min.

More details

No, there is no direct bus from St. Louis to Zacatecas. However, there are services departing from St Louis, Mo and arriving at Zacatecas via Oklahoma City, Ok, Dallas, Tx, Nuevo Laredo and Monterrey. The journey, including transfers, takes approximately 38 h 50 min.

More details

The distance between St. Louis and Zacatecas is 1325 miles. The road distance is 1503.9 miles.

Get driving directions

The best way to get from St. Louis to Zacatecas without a car is to bus which takes 38 h 50 min and costs $160 - $380.

More details

It takes approximately 8 h 12 min to get from St. Louis to Zacatecas, including transfers.

More details

St. Louis to Zacatecas bus services, operated by Greyhound USA, depart from St Louis, Mo station.

More details

The best way to get from St. Louis to Zacatecas is to fly which takes 8 h 12 min and costs $360 - $1,300. Alternatively, you can bus, which costs $160 - $380 and takes 38 h 50 min.

Mode details

There is no direct flight from St. Louis Airport to Zacatecas Airport. The quickest flight takes 5 h 19 min and has one stopover.

Search flights

St. Louis to Zacatecas bus services, operated by Omnibus de Mexico, arrive at Zacatecas station.

More details

Yes, the driving distance between St. Louis to Zacatecas is 1504 miles. It takes approximately 25 h 34 min to drive from St. Louis to Zacatecas.

Get driving directions

Southwest Airlines, Volaris, American Airlines and two other airlines offer flights from St. Louis Airport to Zacatecas Airport.

Search flights

Map of how to get from St. Louis to Zacatecas.
Launch map view
  • Distance: 1324.6 miles
  • Duration: 8 h 12 min

What companies run services between St. Louis, MO, USA and Zacatecas, Mexico?

American Airlines, Southwest Airlines and three other airlines fly from St. Louis to Zacatecas 3 times a day. Alternatively, you can take a bus from St. Louis to Zacatecas via Oklahoma City, Ok, Dallas, Tx, Nuevo Laredo, Mx, Nuevo Laredo, and Monterrey in around 38 h 50 min.

Airlines
American Airlines
Website
aa.com
Flights from St. Louis to Zacatecas via Dallas/Ft.Worth
Ave. Duration
5 h 19 min
When
Saturday
Estimated price
$320 - $2,200
Flights from St. Louis to Aguascalientes via Dallas/Ft.Worth
Ave. Duration
7 h 6 min
When
Every day
Estimated price
$250 - $1,700
Flights from St. Louis to Aguascalientes via Chicago O'Hare, Dallas/Ft.Worth
Ave. Duration
8 h 11 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$310 - $1,900
Flights from St. Louis to Aguascalientes via Charlotte, Dallas/Ft.Worth
Ave. Duration
11 h 8 min
When
Every day
Estimated price
$370 - $2,100
Flights from St. Louis to San Luis Potosi via Dallas/Ft.Worth
Ave. Duration
5 h 32 min
When
Every day
Estimated price
$210 - $1,500
Flights from St. Louis to San Luis Potosi via Chicago O'Hare, Dallas/Ft.Worth
Ave. Duration
9 h
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$270 - $1,700
Flights from St. Louis to San Luis Potosi via Charlotte, Dallas/Ft.Worth
Ave. Duration
10 h 12 min
When
Monday, Wednesday, Thursday, Friday, Saturday and Sunday
Estimated price
$320 - $1,900
United Airlines
Website
united.com
Flights from St. Louis to Aguascalientes via Houston
Ave. Duration
5 h 20 min
When
Every day
Estimated price
$270 - $1,600
Flights from St. Louis to Aguascalientes via Chicago O'Hare, Houston
Ave. Duration
8 h 36 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$340 - $1,900
Flights from St. Louis to San Luis Potosi via Houston
Ave. Duration
5 h 20 min
When
Every day
Estimated price
$230 - $1,400
Flights from St. Louis to San Luis Potosi via Chicago O'Hare, Houston
Ave. Duration
8 h 16 min
When
Saturday
Estimated price
$300 - $1,600
Delta
Website
delta.com
Flights from St. Louis to Zacatecas via Atlanta, Mexico City
Ave. Duration
10 h 20 min
When
Every day
Estimated price
$500 - $3,100
Aeroméxico
Website
world.aeromexico.com
Flights from St. Louis to Zacatecas via Atlanta, Mexico City
Ave. Duration
10 h 20 min
When
Every day
Estimated price
$500 - $3,100
Volaris
Website
volaris.com
Flights from St. Louis to Zacatecas via Chicago Midway
Ave. Duration
5 h 53 min
When
Sunday
Estimated price
$350 - $1,200
Train operators
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from St. Louis Gateway Station to San Antonio Amtrak
Ave. Duration
26 h
Frequency
Once daily
Estimated price
$130 - $390
Website
amtrak.com
Coach Seat
$130 - $200
Flexi Coach Seat
$240 - $350
Business Coach Seat
$280 - $390
Room
$500 - $750
Bus operators
ETN
Website
etn.com.mx
Bus from Aguascalientes to Zacatecas
Ave. Duration
2 h
Frequency
Every 15 minutes
Estimated price
$11 - $23
Schedules at
venta.etn.com.mx
Web Advance
$15 - $23
Full Fare
$11 - $16
Regular Price
$14
Internet Discount
$12
Bus from Nuevo Laredo to Zacatecas
Ave. Duration
10 h
Frequency
Twice daily
Estimated price
$40 - $80
Schedules at
venta.etn.com.mx
Web Advance
$40 - $65
Full Fare
$55 - $80
Grupo Senda
Phone
US: (81) 8151 5253, México: 1 800 733 7330
Website
ticket.gruposenda.com
Bus from Aguascalientes to Zacatecas
Ave. Duration
1 h 50 min
Frequency
Every 3 hours
Estimated price
$14 - $21
Schedules at
ticket.gruposenda.com
Diamante
$15 - $21
Ejecutivo
$14 - $15
Bus from Nuevo Laredo to Monterrey
Ave. Duration
3 h 10 min
Frequency
Every 30 minutes
Estimated price
$18 - $26
Schedules at
ticket.gruposenda.com
Diamante
$18 - $26
Ejecutivo
$21 - $23
Omnibus de Mexico
Website
odm.com.mx
Bus from San Luis Potosí to Zacatecas
Ave. Duration
2 h 48 min
Frequency
Hourly
Estimated price
$11 - $17
Schedules at
odm.com.mx
Bus from Monterrey to Zacatecas
Ave. Duration
6 h
Frequency
Every 3 hours
Estimated price
$24 - $35
Schedules at
odm.com.mx
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from St Louis, Mo to Oklahoma City, Ok
Ave. Duration
10 h 50 min
Frequency
Hourly
Estimated price
$55 - $150
Website
greyhound.com
Economy
$55 - $95
Flexible
$110 - $150
Bus from Oklahoma City, Ok to Dallas, Tx
Ave. Duration
4 h 45 min
Frequency
Hourly
Estimated price
$26 - $65
Website
greyhound.com
Economy
$26 - $45
Flexible
$45 - $65
Bus from Dallas, Tx to Nuevo Laredo, Mx
Ave. Duration
11 h 35 min
Frequency
Hourly
Estimated price
$45 - $110
Website
greyhound.com
Economy
$45 - $75
Flexible
$85 - $110
Bus from San Antonio, Tx to Laredo, Tx
Ave. Duration
2 h 30 min
Frequency
Every 30 minutes
Estimated price
$21 - $50
Website
greyhound.com
Economy
$21 - $35
Flexible
$35 - $50
Estrella Blanca
Website
estrellablanca.com.mx
Bus from Nuevo Laredo to Monterrey
Ave. Duration
3 h
Frequency
Hourly
Estimated price
$12 - $22
Schedules at
estrellablanca.com.mx
Económico
$12 - $18
Primera Select
$16 - $22
Greyhound Mexico
Phone
01-800 890 6821
Website
greyhound.com.mx
Bus from San Antonio to Nuevo Laredo
Ave. Duration
5 h 30 min
Frequency
Twice daily
Estimated price
$45 - $65
Schedules at
greyhound.com.mx

Want to know more about travelling around Mexico

Rome2rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.